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SVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIADGVRSPHGTQWEGAAQAAAQARADSDL AGVRMLADRLRTAARTAVDGGSAIEAAKHEALTVIAATNAMGFEVADDLTVWNRMGAALRRNDAELLGIS VRTGAAQLAAVDHAVATELDSVTAGFDALNIGEGPVIAPIAAGDDGQSFGQCFADRFKDDIGENMVQGVF VGGALGALRGAVLGVLGGPLGMLGGSVAGFVGGAAGGAMISGPARTAVTSAWDCL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | - | 100% (266) | hypothetical protein Mvan_5711 |
| M. vanbaalenii PYR-1 | Mvan_3447 | - | 2e-06 | 33.94% (109) | hypothetical protein Mvan_3447 |
| M. vanbaalenii PYR-1 | Mvan_5126 | - | 2e-05 | 25.93% (162) | hypothetical protein Mvan_5126 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2102c | - | 1e-18 | 31.46% (178) | transmembrane protein |
| M. gilvum PYR-GCK | Mflv_1972 | - | 4e-18 | 33.33% (168) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv2077c | - | 1e-18 | 31.46% (178) | transmembrane protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0376 | - | 1e-12 | 25.73% (241) | hypothetical protein MAB_0376 |
| M. marinum M | MMAR_4061 | - | 2e-22 | 35.20% (179) | hypothetical protein MMAR_4061 |
| M. avium 104 | MAV_0692 | - | 8e-22 | 30.89% (246) | hypothetical protein MAV_0692 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 4e-20 | 34.95% (186) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 9e-75 | 51.12% (268) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1136 | - | 1e-14 | 37.17% (113) | hypothetical protein MUL_1136 |
CLUSTAL 2.0.9 multiple sequence alignment
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mb2102c|M.bovis_AF2122/97 -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
Rv2077c|M.tuberculosis_H37Rv -----------MLATLSQIRAWSTEHLIDAAGYWTETADRWEDVFLQMRN
MAV_0692|M.avium_104 -----------MPATLSQIQAWSTEHLIDAAAYWTQTADRWEDAFLTMRN
MMAR_4061|M.marinum_M -----------MPATLSQIRAWSTEHLIDSAGYWTKTADRWEDTFFQIRN
MUL_1136|M.ulcerans_Agy99 -----------MVLTLSQVQAWRTEHLIEAATYWSKTADQWEDVFLQMRN
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
MAB_0376|M.abscessus_ATCC_1997 -----------MRPTISQLRAWDVANLDAAAKAIEDASKNLDLSIDGVVR
: *.:. * . .* :: :.
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV
Mb2102c|M.bovis_AF2122/97 ---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
Rv2077c|M.tuberculosis_H37Rv ---QAHAIAWNGAGGDGLRQRTRADFSTVSGIADQLRRAATIARNGAGTI
MAV_0692|M.avium_104 ---QAQSITWHGAGGDALRQRTGADVSVVSGKADQLRQAAGIARNGASEI
MMAR_4061|M.marinum_M ---QSYALDWNGAGGAALRERTSADLPLVSAKADVLRQAAGIARDGASGI
MUL_1136|M.ulcerans_Agy99 ---QSHTLVWEGAGGDALRQRTGADLAIVSTKADELRQASKIARDGAGTI
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI
MAB_0376|M.abscessus_ATCC_1997 -DLDSAESFWKGKAFQSAYDQASNEQSSTNRLSFAISNVAEAVRGGHSAL
*.* . . :. : . . : . . :
Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELLG
TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVLA
Mb2102c|M.bovis_AF2122/97 DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
Rv2077c|M.tuberculosis_H37Rv DAAQRRVMYAVEDAQDAGFNVGEDLSVTDTKTTQPAAVQAARLAQAQALA
MAV_0692|M.avium_104 SAAQRRVLYGVEDAQNAGFTVGEDLSVTDTRSTSP-AERAARQAQAEAFA
MMAR_4061|M.marinum_M SAAQRRVLYAIEDAQNVGFTVGEDLSVTDTRSSGTAAEQVARHAQAQAFA
MUL_1136|M.ulcerans_Agy99 GIAQRRVLHAVEDAHNAGFTVGEDFSVTDIRTSRRSAEQAARQAQAQAQA
Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNR-AYDLETAAARMTAATEHA
MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTS-RVDVSTMAARYTAAREHA
MAB_0376|M.abscessus_ATCC_1997 TAARDKVMLLVDEATSKGLHVADDGTVTAPEGNRELQAEARRLTDAIRQA
*: .: : : : * :* :: . * : .
Mvan_5711|M.vanbaalenii_PYR-1 ISVRTGAAQLAAVDHAVATELDSVT-AGFDALNIGEGPVIAPIAAG----
TH_3926|M.thermoresistible__bu ATVRVGAAQLVSTDHAVAQRLREAT-DDFDSFDFARNPIIQPLSTD----
Mb2102c|M.bovis_AF2122/97 GDIRLRVGQLVAAENEVSGQLAATT-GDVGNVRFAGAPVVAHSA------
Rv2077c|M.tuberculosis_H37Rv GDIRLRVGQLVAAENEVSGQLAATT-GDVGNVRFAGAPVVAHSA------
MAV_0692|M.avium_104 ADLRLRAEQLEAADTKAAGQITATA-GDVGNATFT--PAHNGNG------
MMAR_4061|M.marinum_M GDIRLRAEQLDAAEVKVAGQLSAIR-AGLSGIGFAENPIFNPVAH-----
MUL_1136|M.ulcerans_Agy99 QATDIRQRAVEPVPPPAPGRLPPLTPGEMATPRLPAPPPQPPIR------
Mflv_1972|M.gilvum_PYR-GCK EFIRWRVEQLVATDALIGQQLQANA-AELEGIRFEGDRDGNGTDPTIRLV
MSMEG_5600|M.smegmatis_MC2_155 ENIQWNANQLLATDTLIGRRLTAKA-AELNGVRFDDEPEG----------
MAB_0376|M.abscessus_ATCC_1997 LKSLEEADRTSSNDLRKASASVDAEHNSASTQPAAFMPASSGGAASG---
.
Mvan_5711|M.vanbaalenii_PYR-1 ----------------------------------DDGQSFGQCFADRFKD
TH_3926|M.thermoresistible__bu ----------------------------------SDEHHFGTCFAESFKE
Mb2102c|M.bovis_AF2122/97 -----------------------------------------VQLVDFFKQ
Rv2077c|M.tuberculosis_H37Rv -----------------------------------------VQLVDFFKQ
MAV_0692|M.avium_104 -----------------------------------------VQLVD-FKQ
MMAR_4061|M.marinum_M ----------------------------------APANRIGIQPVD-FKQ
MUL_1136|M.ulcerans_Agy99 ------------------------------------------GGADLAPA
Mflv_1972|M.gilvum_PYR-GCK DNKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAESAEGADTAE
MSMEG_5600|M.smegmatis_MC2_155 -------------------------------------TIRAASFGDGFKQ
MAB_0376|M.abscessus_ATCC_1997 ----------------------------------SMKAGSGGFSGGGFGG
Mvan_5711|M.vanbaalenii_PYR-1 DIG-----------------------------------------------
TH_3926|M.thermoresistible__bu DVG-----------------------------------------------
Mb2102c|M.bovis_AF2122/97 DGPTPPPPG----APHPSGGADGPYSDPITSMMLPPAGTEA---------
Rv2077c|M.tuberculosis_H37Rv DGPTPPPPG----APHPSGGADGPYSDPITSMMLPPAGTEA---------
MAV_0692|M.avium_104 DG--------------------GPVCD-----------------------
MMAR_4061|M.marinum_M DSGAPPPFAPWDTADETPPPGKGPFNRMLLPSSTPPLEPDD---------
MUL_1136|M.ulcerans_Agy99 EP------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK SPLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALERILSQHTGT
MSMEG_5600|M.smegmatis_MC2_155 SPFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG---------
MAB_0376|M.abscessus_ATCC_1997 GSGGGHGGGFGGGHGGGGGGGHSVPDGSYSNTGAPSLRPSG---------
Mvan_5711|M.vanbaalenii_PYR-1 -------------ENMVQGVFVG---------------------------
TH_3926|M.thermoresistible__bu -------------KNMVQGVFVG---------------------------
Mb2102c|M.bovis_AF2122/97 -----------PVSDATKRWVDN-------------------------MV
Rv2077c|M.tuberculosis_H37Rv -----------PVSDATKRWVDN-------------------------MV
MAV_0692|M.avium_104 ------------DPDYNDRFFRK-------------------------FM
MMAR_4061|M.marinum_M -----------PLNDALRRITNSPAR----------------------PA
MUL_1136|M.ulcerans_Agy99 -------------PPVVRTPMEP---------------------------
Mflv_1972|M.gilvum_PYR-GCK GRGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESAQGALDDAL
MSMEG_5600|M.smegmatis_MC2_155 -----------PLPPPQYAACQQELAFLQG----------------QEAA
MAB_0376|M.abscessus_ATCC_1997 -------------PSVFMNLDAG--------------------------Q
Mvan_5711|M.vanbaalenii_PYR-1 ----------------------------------GALGALRGAVLGVLGG
TH_3926|M.thermoresistible__bu ----------------------------------GAIGAARGALMGILGG
Mb2102c|M.bovis_AF2122/97 NELAARPPDDPIAVEARRLAFQALHRPCNSAEWTAAVAGFAGSSAGVVGT
Rv2077c|M.tuberculosis_H37Rv NELAARPPDDPIAVEARRLAFQALHRPCNSAEWTAAVAGFAGSSAGVVGT
MAV_0692|M.avium_104 GRVGAG----------------------------AAIGGLAGAPEAGVG-
MMAR_4061|M.marinum_M GPLTQDQIKALVDAEVNDKLSQAEKFSLRTLLSKTFEGCGAGGIAAGVGG
MUL_1136|M.ulcerans_Agy99 ---------------------------------PARLGGPIAGGPVPPGS
Mflv_1972|M.gilvum_PYR-GCK AQSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLNAAADEVGQ
MSMEG_5600|M.smegmatis_MC2_155 LRARLADFGIHPG----------------EAPSSTSSGGDLTATATQIG-
MAB_0376|M.abscessus_ATCC_1997 MEVARKIIEEGLRRG----------------LSPEAIQIALATALTESGL
*
Mvan_5711|M.vanbaalenii_PYR-1 P------------LGMLGGSVAGFVGGAAGGAMISGPARTAVTSAWDCL-
TH_3926|M.thermoresistible__bu P------------IGVFGGGVLGFVGGAAGGALISGPARTAVTSAWDCL-
Mb2102c|M.bovis_AF2122/97 A-------------LAIPAGPADWALLGAALLGVGGSGAAVVNCATK---
Rv2077c|M.tuberculosis_H37Rv A-------------LAIPAGPADWALLGAALLGVGGSGAAVVNCATK---
MAV_0692|M.avium_104 ---------------AIPGAIIGGAAGGIEAFIEGATESEPPKCGK----
MMAR_4061|M.marinum_M L-------------ITGPLEPLDIAG-GCAAGAIGDGGKYLFEYGGK---
MUL_1136|M.ulcerans_Agy99 --------------IPHPVQPPHSHHGPPVLGKDELPDLGEFNPG-----
Mflv_1972|M.gilvum_PYR-GCK GRVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDVAHDIDVFR
MSMEG_5600|M.smegmatis_MC2_155 -----------AEIATFPPGTRADALAERMTGLHLNQADAARATDIAAAR
MAB_0376|M.abscessus_ATCC_1997 RSLAN---------SSVPDSMMFPNDGVGHDHDSVGPFQQRQSWGATADL
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0692|M.avium_104 --------------------------------------------------
MMAR_4061|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK NWSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVNAGRHVDDA
MSMEG_5600|M.smegmatis_MC2_155 IWGETG------------GTSKMPDGSIIVLPANIRQTDVMKVFPDGSVT
MAB_0376|M.abscessus_ATCC_1997 MDPTKSAGKFYDQLVKVSGWQDMSVAQAAQSVQRSAFPDAYAKYEAQAAQ
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0692|M.avium_104 --------------------------------------------------
MMAR_4061|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK LDAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGNFGFEDANA
MSMEG_5600|M.smegmatis_MC2_155 VLRGVDVTQYLPR-------------------------------------
MAB_0376|M.abscessus_ATCC_1997 IFHQVTGR------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0692|M.avium_104 --------------------------------------------------
MMAR_4061|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK LLQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATADEAASAVS
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0376|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mb2102c|M.bovis_AF2122/97 --------------------------------------------------
Rv2077c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_0692|M.avium_104 --------------------------------------------------
MMAR_4061|M.marinum_M --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK TALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGSTVRVV
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
MAB_0376|M.abscessus_ATCC_1997 --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 ------------------
TH_3926|M.thermoresistible__bu ------------------
Mb2102c|M.bovis_AF2122/97 ------------------
Rv2077c|M.tuberculosis_H37Rv ------------------
MAV_0692|M.avium_104 ------------------
MMAR_4061|M.marinum_M ------------------
MUL_1136|M.ulcerans_Agy99 ------------------
Mflv_1972|M.gilvum_PYR-GCK LKGDGNGGWYVLTGFPKP
MSMEG_5600|M.smegmatis_MC2_155 ------------------
MAB_0376|M.abscessus_ATCC_1997 ------------------