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LRQRTGADLQIVSGIAEHLRQASGLAREGAGTIGAAQRRVIYAVQDAHNAGFNVEEDLSVTDTRTSRTFA EQAARQAQAQALAGDIRQRATQLIGVEHEVAAKIATATAPLNTVGFHEPPIAPSLPTPVPHNEKPQIHAV DRSWKQDPPSPMPGDPKDMTAVQARAAWDAVNADIARYNARCGRTFVLPNEQAAYDACIADKGSLFERQA AIRARLGELGVPVEGEPPPAPDPAGPQPNEGLPPPGVSPPAESNLTVGPPSRPIQQARGGESLWDENGGE WRYFPGDNYRYPHWDYNPHDSPTARWQNIPIGDLPTHK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1949c | - | - | 100% (319) | hypothetical protein Rv1949c |
| M. tuberculosis H37Rv | Rv2077c | - | 8e-36 | 54.90% (153) | transmembrane protein |
| M. tuberculosis H37Rv | Rv0614 | - | 1e-12 | 39.44% (142) | hypothetical protein Rv0614 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1984c | - | 1e-180 | 99.67% (300) | hypothetical protein Mb1984c |
| M. gilvum PYR-GCK | Mflv_1972 | - | 7e-08 | 32.74% (113) | hypothetical protein Mflv_1972 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0016 | - | 2e-07 | 28.16% (103) | hypothetical protein MAB_0016 |
| M. marinum M | MMAR_0482 | - | 5e-69 | 47.38% (325) | hypothetical protein MMAR_0482 |
| M. avium 104 | MAV_3647 | - | 3e-37 | 67.83% (115) | hypothetical protein MAV_3647 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 6e-22 | 28.97% (290) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 6e-12 | 32.26% (124) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1133 | - | 6e-68 | 46.77% (325) | hypothetical protein MUL_1133 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 2e-08 | 29.66% (118) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1949c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1984c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0482|M.marinum_M -------MAASGIPDLSALLAWPTDHLTEAAAHWDNVGEHTYAVAHQLWR
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAV_3647|M.avium_104 -----------MPVTLSQVRAWTTEHLVNAASYWSKTADQWEDVFLQMRN
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGAQG
Rv1949c|M.tuberculosis_H37Rv ----------------WLRQRTGADLQIVSGIAEHLRQASGLAREGAGTI
Mb1984c|M.bovis_AF2122/97 -----------------------------------MRQASGLAREGAGTI
MMAR_0482|M.marinum_M DATS---IDWSGHAAGALRAATHADLQTTSAAVDQLQEAARVARNGASDL
MUL_1133|M.ulcerans_Agy99 -----------------MRAATHADLQTTSAAVDQLQEAARVARNGASDL
MAV_3647|M.avium_104 QSYS---ITWKGAGGDGLRQRTGADLSVVSGKADQLRKAAGIARNGASDI
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVTADTSVVRRQGDVHRVAADIAARGSEDI
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERATQNLNTVRAAGDIARSAADLAENSSADI
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTKRDRDTVELLAERLYFGASIAESGAAMV
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARADSDLAGVRMLADRLRTAARTAVDGGSAI
MAB_0016|M.abscessus_ATCC_1997 ---LLDGLRGSGQFVEAFRTRLKSYIDKTRPKVDKLKSAKQVAESSEQQL
. * . :
Rv1949c|M.tuberculosis_H37Rv GAAQRRVIYAVQDAHNAGFNVEEDLSVTDTRTSRTFAEQAARQAQAQALA
Mb1984c|M.bovis_AF2122/97 GAAQRRVIYAVQDAHNAGFNVEEDLSVTDTRTSRTFAEQAARQAQAQALA
MMAR_0482|M.marinum_M YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
MUL_1133|M.ulcerans_Agy99 YAARSRVRYAVTDAQAAGFQVEEDLSVTDRMTGGSAAQRAARQAQAQAFA
MAV_3647|M.avium_104 GAAQRRVLYAVEDAQNAGFTVGEDLSVTDTRSSTTPADHAARQARAEAFA
Mflv_1972|M.gilvum_PYR-GCK QGARSRVLEAIAEAEQDDFTVGEDLSVTDNR-AYDLETAAARMTAATEHA
MSMEG_5600|M.smegmatis_MC2_155 SAAKRDALQSISDAEADGFEVNEDLSVRDTS-RVDVSTMAARYTAAREHA
TH_3926|M.thermoresistible__bu DQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVLA
Mvan_5711|M.vanbaalenii_PYR-1 EAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELLG
MAB_0016|M.abscessus_ATCC_1997 KGAKDKAVYAVHDPEDEDFNVNEDLSVTERR-SHSGLDRLKRAIRRRWLQ
*: . : . * * :**:: : *
Rv1949c|M.tuberculosis_H37Rv GDIRQRATQLIGVEHEVAAKIATATAPLNTVGFHEPPIAPSLPTPVPHNE
Mb1984c|M.bovis_AF2122/97 GDIRQRATQLIGVEHEVAAKIATATAPLNTVGFHEPPIAPSLPTPVPHNE
MMAR_0482|M.marinum_M GDLRQRAAQLVGLDAQVATKVTAAVAGIGSS-------FPQIPAPAAPPM
MUL_1133|M.ulcerans_Agy99 GDLPQRAAQLVGLDAQVATKVTAAVAGIGSS-------FPQIPAPAAPPM
MAV_3647|M.avium_104 GDIRARAEQLEGVDRKVARELTTTTADLGTVG------------TVASSG
Mflv_1972|M.gilvum_PYR-GCK EFIRWRVEQLVATDALIGQQLQANAAELEGIRFEGDRDGNGTDPTIRLVD
MSMEG_5600|M.smegmatis_MC2_155 ENIQWNANQLLATDTLIGRRLTAKAAELNGVRFDDEPEG-----------
TH_3926|M.thermoresistible__bu ATVRVGAAQLVSTDHAVAQRLREATDDFDSFD------------------
Mvan_5711|M.vanbaalenii_PYR-1 ISVRTGAAQLAAVDHAVATELDSVTAGFDALN------------------
MAB_0016|M.abscessus_ATCC_1997 GILHTRAQELVATDNAIARKLHEIAQDLSNFHLEGPDGNTDFSGDPNHPK
: . :* . : :. .: . :
Rv1949c|M.tuberculosis_H37Rv K----------------------------------PQIHAVD-RSWKQDP
Mb1984c|M.bovis_AF2122/97 K----------------------------------PQIHAVD-RSWKQDP
MMAR_0482|M.marinum_M G----------------------------------NPVRAVDNRTFKQNP
MUL_1133|M.ulcerans_Agy99 G----------------------------------NPVRAVDNRTFKQNP
MAV_3647|M.avium_104 R----------------------------------DDVQPVD---AVAGL
Mflv_1972|M.gilvum_PYR-GCK NKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAESAEGADTAES
MSMEG_5600|M.smegmatis_MC2_155 ------------------------------------TIRAASFGDGFKQS
TH_3926|M.thermoresistible__bu ----------------------------------------------FARN
Mvan_5711|M.vanbaalenii_PYR-1 ----------------------------------------------IGEG
MAB_0016|M.abscessus_ATCC_1997 IMGPAKPLG--------------------PIEQEDYDLGYTFLDENGNPL
Rv1949c|M.tuberculosis_H37Rv PSPMPGDPKDMTAVQARAAWDAVNADIARYNARCGRTFVL----------
Mb1984c|M.bovis_AF2122/97 PSPMPGDPKDMTAVQARAAWDAVNADIARYNARCGRTFVL----------
MMAR_0482|M.marinum_M P-PAPVDPKDMTAEEARAAWADINSEIGKYNARCGRTFVL----------
MUL_1133|M.ulcerans_Agy99 P-PAPVDPKDMTAEEARAAWADINSEIGKYNARCGRTFVL----------
MAV_3647|M.avium_104 PPDIPDRIHVVCIEHARGMPWEFECLVAYPDGTTDIYHTD----------
Mflv_1972|M.gilvum_PYR-GCK PLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALERILSQHTGTG
MSMEG_5600|M.smegmatis_MC2_155 PFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG----------
TH_3926|M.thermoresistible__bu PIIQPLSTDSDEHHFGTCFAESFKEDVGKNMVQG--VFVG----------
Mvan_5711|M.vanbaalenii_PYR-1 PVIAPIAAGDDGQSFGQCFADRFKDDIGENMVQG--VFVG----------
MAB_0016|M.abscessus_ATCC_1997 PMLDENGNVVIDPKTGRPVPDSVWGDPADNNADGSPRVPHP---------
* .
Rv1949c|M.tuberculosis_H37Rv ----------PNEQAAYDACIADKGSLFER----------------QAAI
Mb1984c|M.bovis_AF2122/97 ----------PNEQAAYDACIADKGSLLER----------------QAAI
MMAR_0482|M.marinum_M ----------PTEQGAYDACIADKGPLLDR----------------QAAI
MUL_1133|M.ulcerans_Agy99 ----------PTEQGAYDACIADKGPLLDR----------------QAVI
MAV_3647|M.avium_104 ----------EDESGIFP--------------------------------
Mflv_1972|M.gilvum_PYR-GCK RGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESAQGALDDALA
MSMEG_5600|M.smegmatis_MC2_155 ----------PLPPPQYAACQQELAFLQG----------------QEAAL
TH_3926|M.thermoresistible__bu --------------GAIGAARG----------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------GALGALRG----------------------------
MAB_0016|M.abscessus_ATCC_1997 --------PRDHHFADMDANDPYRTLPTG---------------TTVGPN
Rv1949c|M.tuberculosis_H37Rv RARLGELGVPVE---------------GEPPPAP---DPAGPQPN--EG-
Mb1984c|M.bovis_AF2122/97 RARLGELGVPVE---------------GEPPPAP---DPAGPQPN--EG-
MMAR_0482|M.marinum_M RARLGQLGIPVE---------------GEDPTHPGTAEPPFPPPTRING-
MUL_1133|M.ulcerans_Agy99 RARLGQLGIPVE---------------GEDPTHPGTAEPPFPPPTRING-
MAV_3647|M.avium_104 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK QSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLNAAADEVGQG
MSMEG_5600|M.smegmatis_MC2_155 RARLADFGIHPG----------------EAPSSTSSGGDLTATATQIG--
TH_3926|M.thermoresistible__bu -ALMGILGGPIG--------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 -AVLGVLGGPLG--------------------------------------
MAB_0016|M.abscessus_ATCC_1997 GERIALVSRPPD-------------DPAWAENQTKNGKSVYVTQTEAYD-
Rv1949c|M.tuberculosis_H37Rv --------------LPPPGVSPPAESNLTVGPPSRPIQQARGG-----ES
Mb1984c|M.bovis_AF2122/97 --------------LPPPGVSPPAESNLTVGPPSRPIQQARGG-----ES
MMAR_0482|M.marinum_M --------------LTEHGAQR-VEGRDGHGVNDNAMQDAVAHPIEPPQF
MUL_1133|M.ulcerans_Agy99 --------------LTEHGAQR-VEGRDGHGVNDNAMQDAVAHPIEPPQF
MAV_3647|M.avium_104 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK RVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDVAHDIDVFRN
MSMEG_5600|M.smegmatis_MC2_155 ----------AEIATFPPGTRADALAERMTGLHLNQADAARATDIAAARI
TH_3926|M.thermoresistible__bu --------------VFGGGVLGFVGGAAGGALISGPARTAVTSAWDCL--
Mvan_5711|M.vanbaalenii_PYR-1 --------------MLGGSVAGFVGGAAGGAMISGPARTAVTSAWDCL--
MAB_0016|M.abscessus_ATCC_1997 ------------VTRQPPQSLGKLQGVDGSKVYQGSIVYDKASGRMYVVG
Rv1949c|M.tuberculosis_H37Rv LWDENG------------------GEWRYFPGDNYRYPHWDYNPHDSPTA
Mb1984c|M.bovis_AF2122/97 LWDENG------------------GEWRYFPGDNYRYPHWDYNPHDSPTA
MMAR_0482|M.marinum_M MPDQYG------------------GTWRYIGKD----ATVSLNENGQVTT
MUL_1133|M.ulcerans_Agy99 MPDQYG------------------GTWRYIGKD----ATVSLNENGQVTT
MAV_3647|M.avium_104 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK WSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVNAGRHVDDAL
MSMEG_5600|M.smegmatis_MC2_155 WGETG------------GTSKMPDGSIIVLPANIRQTDVMKVFPDGSVTV
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 NHGDGSGDTARGMWRSDPVDPNHPNDWVKTLRYQGDVPSLPGSRESSLVA
Rv1949c|M.tuberculosis_H37Rv RWQNIPIGDLPTHK------------------------------------
Mb1984c|M.bovis_AF2122/97 RWQNIPIGDLPTHK------------------------------------
MMAR_0482|M.marinum_M AWANSRNGWRNP--------------------------------------
MUL_1133|M.ulcerans_Agy99 AWANSRNGWRNP--------------------------------------
MAV_3647|M.avium_104 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK DAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGNFGFEDANAL
MSMEG_5600|M.smegmatis_MC2_155 LRGVDVTQYLPR--------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 LPHGGVALFGADDYAPAEGRNMAVG------AISAATPEGLLQARPVTDL
Rv1949c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1984c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAV_3647|M.avium_104 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK LQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATADEAASAVST
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 LPAGKTPWPGGAPYAALPTGVHWDPALRADVVDTRVSIWRDVPGVRGAYP
Rv1949c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1984c|M.bovis_AF2122/97 --------------------------------------------------
MMAR_0482|M.marinum_M --------------------------------------------------
MUL_1133|M.ulcerans_Agy99 --------------------------------------------------
MAV_3647|M.avium_104 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK ALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGSTVRVVL
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 PVTYQTSVPIFQPNS-----------------------------------
Rv1949c|M.tuberculosis_H37Rv -----------------
Mb1984c|M.bovis_AF2122/97 -----------------
MMAR_0482|M.marinum_M -----------------
MUL_1133|M.ulcerans_Agy99 -----------------
MAV_3647|M.avium_104 -----------------
Mflv_1972|M.gilvum_PYR-GCK KGDGNGGWYVLTGFPKP
MSMEG_5600|M.smegmatis_MC2_155 -----------------
TH_3926|M.thermoresistible__bu -----------------
Mvan_5711|M.vanbaalenii_PYR-1 -----------------
MAB_0016|M.abscessus_ATCC_1997 -----------------