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PATLSQVRAWSTEHLIDTAGYWTKTADQWENAFFQMRNQSYALGWSGAGGDALRERTSADLPIVGAKADM LRQAAGIAGNGASDISAAQRRVLYAVEDAHNAGFTVGEDLSVTDTHRSGTPAEQAARQAQAQAFAGDIRL HARQLDGADAKVAGQLTAATADLSSVGFAQNPIPATQAPTTHRNGVQLVDFKQNGGEPPPFAPWDTPDGT PPPGAPGLSPELQQMILGGDPANLTGQGLLDNLQQLVQSLPENDPRTAWLRGQVADLQAHMSDIDYARTH CTTSDWFDRTTLFASGLVSTGILTLTAETGVGGVAAVASGFGTLVAGKNLLGCLVGSK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0116 | - | - | 100% (339) | hypothetical protein MMAR_0116 |
| M. marinum M | MMAR_4061 | - | 7e-92 | 76.50% (217) | hypothetical protein MMAR_4061 |
| M. marinum M | MMAR_0484 | - | 1e-52 | 56.72% (201) | hypothetical protein MMAR_0484 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0631 | - | 5e-76 | 63.79% (232) | hypothetical protein Mb0631 |
| M. gilvum PYR-GCK | Mflv_1972 | - | 3e-23 | 30.66% (274) | hypothetical protein Mflv_1972 |
| M. tuberculosis H37Rv | Rv0614 | - | 5e-76 | 63.79% (232) | hypothetical protein Rv0614 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0016 | - | 9e-13 | 28.83% (163) | hypothetical protein MAB_0016 |
| M. avium 104 | MAV_2254 | - | 3e-85 | 65.75% (254) | hypothetical protein MAV_2254 |
| M. smegmatis MC2 155 | MSMEG_5600 | - | 5e-25 | 39.18% (171) | hypothetical protein MSMEG_5600 |
| M. thermoresistible (build 8) | TH_3926 | - | 2e-24 | 33.61% (244) | PUTATIVE putative hypothetical protein Mvan_5711 |
| M. ulcerans Agy99 | MUL_1136 | - | 8e-53 | 53.85% (221) | hypothetical protein MUL_1136 |
| M. vanbaalenii PYR-1 | Mvan_5711 | - | 1e-18 | 33.52% (176) | hypothetical protein Mvan_5711 |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3926|M.thermoresistible__bu ---MIDALPASGLPTLSQIQGWQTAHLRSAARRWRVTADTWTSIYDDIAA
Mvan_5711|M.vanbaalenii_PYR-1 -----MSVVAHGLPTLSQIENWETAHLACAARRWTAAAEHWESSFGLIAD
Mflv_1972|M.gilvum_PYR-GCK ------------MPSRSEVESWETADLDAAASRWRTAGDVLESAFEQHRQ
MSMEG_5600|M.smegmatis_MC2_155 MSPTATPAEGGEGLSRSRIESWDTTHLENATARWRATATELEGHFEQLRQ
Mb0631|M.bovis_AF2122/97 -----------MPAIPFQGEAR--------AGRRPGRPRRCPAGVVRCRP
Rv0614|M.tuberculosis_H37Rv -----------MPAIPFQGEAR--------AGRRPGRPRRCPAGVVRCRP
MMAR_0116|M.marinum_M -----------MPATLSQVRAWSTEHLIDTAGYWTKTADQWENAFFQMRN
MAV_2254|M.avium_104 -----------MPATLSQIEAWSTEHLIDAAAYWTQTADRWEDAFLTMRN
MUL_1136|M.ulcerans_Agy99 -----------MVLTLSQVQAWRTEHLIEAATYWSKTADQWEDVFLQMRN
MAB_0016|M.abscessus_ATCC_1997 ------------MPTKSEILNWRTDHLGAAAKTWGDQATQLDTAVNGAQG
. :
TH_3926|M.thermoresistible__bu DLSAKSEIVWEGDASTAAQARTK-RDRDTVELLAERLYFGASIAESGAAM
Mvan_5711|M.vanbaalenii_PYR-1 GVRSPHGTQWEGAAQAAAQARAD-SDLAGVRMLADRLRTAARTAVDGGSA
Mflv_1972|M.gilvum_PYR-GCK NILTPGGTAWEGDAKDAALDRVT-ADTSVVRRQGDVHRVAADIAARGSED
MSMEG_5600|M.smegmatis_MC2_155 HVLAPGGTEWEGDAKDAALERAT-QNLNTVRAAGDIARSAADLAENSSAD
Mb0631|M.bovis_AF2122/97 ---RSMGHVRPGFSPRLGSHRTLRPRWPPYAAASRGLTSGTSRWGWPRLG
Rv0614|M.tuberculosis_H37Rv ---RSMGHVRPGFSPRLGSHRTLRPRWPPYAAASRGLTSGTSRWGWPRLG
MMAR_0116|M.marinum_M ---QSYALGWSGAGGDALRERTS-ADLPIVGAKADMLRQAAGIAGNGASD
MAV_2254|M.avium_104 ---QAQSITWHGAGGDALRQRTG-ADLSVVSGKADLLRQAAGIARNGASD
MUL_1136|M.ulcerans_Agy99 ---QSHTLVWEGAGGDALRQRTG-ADLAIVSTKADELRQASKIARDGAGT
MAB_0016|M.abscessus_ATCC_1997 ---LLDGLRGSGQFVEAFRTRLK-SYIDKTRPKVDKLKSAKQVAESSEQQ
* * .
TH_3926|M.thermoresistible__bu VDQAKEEALLVVRVAGALAFDVREDLSLVDRLATGSPAATAVRLQQSNVL
Mvan_5711|M.vanbaalenii_PYR-1 IEAAKHEALTVIAATNAMGFEVADDLTVWNRMG------AALRRNDAELL
Mflv_1972|M.gilvum_PYR-GCK IQGARSRVLEAIAEAEQDDFTVGEDLSVTDNRAYDLET-AAARMTAATEH
MSMEG_5600|M.smegmatis_MC2_155 ISAAKRDALQSISDAEADGFEVNEDLSVRDTSRVDVST-MAARYTAAREH
Mb0631|M.bovis_AF2122/97 FGVVTAPTRWTLADGRELLF-----FSLPGPRTSGTAAERVARHAQAQTF
Rv0614|M.tuberculosis_H37Rv FGVVTAPTRWTLADGRELLF-----FSLPGPRTSGTAAERVARHAQAQTF
MMAR_0116|M.marinum_M ISAAQRRVLYAVEDAHNAGFTVGEDLSVTDTHRSGTPAEQAARQAQAQAF
MAV_2254|M.avium_104 ISAAQRRVLYGVEDALNAGFTVGEDLSVTDTRSTS-PAERAARQAQAEAF
MUL_1136|M.ulcerans_Agy99 IGIAQRRVLHAVEDAHNAGFTVGEDFSVTDIRTSRRSAEQAARQAQAQAQ
MAB_0016|M.abscessus_ATCC_1997 LKGAKDKAVYAVHDPEDEDFNVNEDLSVTERRSHS-GLDRLKRAIRRRWL
. . . : * ::: *
TH_3926|M.thermoresistible__bu AATVRVGAAQLVSTDHAVAQRLREATDDFDSFDFAR--------------
Mvan_5711|M.vanbaalenii_PYR-1 GISVRTGAAQLAAVDHAVATELDSVTAGFDALNIGE--------------
Mflv_1972|M.gilvum_PYR-GCK AEFIRWRVEQLVATDALIGQQLQANAAELEGIRFEGDRDGNGTDPTIRLV
MSMEG_5600|M.smegmatis_MC2_155 AENIQWNANQLLATDTLIGRRLTAKAAELNGVRFDDEPEG----------
Mb0631|M.bovis_AF2122/97 AGDIRQRAIQLVVSEQEVASKITAATAGIAT-------------------
Rv0614|M.tuberculosis_H37Rv AGDIRQRAIQLVVSEQEVASKITAATAGIAT-------------------
MMAR_0116|M.marinum_M AGDIRLHARQLDGADAKVAGQLTAATADLSS-------------------
MAV_2254|M.avium_104 AADIRLRAEQLDGADTKVSGQLTAATAGLSGGGFAQNSTSNRGG------
MUL_1136|M.ulcerans_Agy99 AQATDIRQRAVEPVPPPAPGRLPPLTP-----------------------
MAB_0016|M.abscessus_ATCC_1997 QGILHTRAQELVATDNAIARKLHEIAQDLSNFHLEGPDGN----------
: .: :
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK DNKTEDKGSQAESSEQRGAGSLSEESTGTWQDMLAPEESAESAEGADTAE
MSMEG_5600|M.smegmatis_MC2_155 -------------------------------------TIRAASFGDGFKQ
Mb0631|M.bovis_AF2122/97 ---------------------------------------------TTFPE
Rv0614|M.tuberculosis_H37Rv ---------------------------------------------TTFPE
MMAR_0116|M.marinum_M ---------------------------------------------VGFAQ
MAV_2254|M.avium_104 -------------------------------------RAQNSSGNGGQPQ
MUL_1136|M.ulcerans_Agy99 ---------------------------------------------GEMAT
MAB_0016|M.abscessus_ATCC_1997 -------------------------------------TDFSGDPNHPKIM
TH_3926|M.thermoresistible__bu NPIIQPLSTDSDEHHFGTCFAESFKEDVG---------------------
Mvan_5711|M.vanbaalenii_PYR-1 GPVIAPIAAGDDGQSFGQCFADRFKDDIG---------------------
Mflv_1972|M.gilvum_PYR-GCK SPLEALLGEGETAEGQQRSSLDEALTEVAGKPVDAPPTALERILSQHTGT
MSMEG_5600|M.smegmatis_MC2_155 SPFDDLLT-----KEQALAAWEKLQTDIASYNSRCAVNIVG---------
Mb0631|M.bovis_AF2122/97 TPSIDDTIIGNDNRDTGVRLVDVKQDGGTSP-PPPFAP------------
Rv0614|M.tuberculosis_H37Rv TPSIDDTIIGNDNRDTGVRLVDVKQDGGTSP-PPPFAP------------
MMAR_0116|M.marinum_M NP-IPATQAPTTHRN-GVQLVDFKQNGGE---PPPFAP------------
MAV_2254|M.avium_104 PGHNAGQPQPATTNHNGVRLVDFTQDNASGPNPPPFAP------------
MUL_1136|M.ulcerans_Agy99 PRLPAPPPQPPIRGG-----ADLAPAEPPPVVRTPMEP------------
MAB_0016|M.abscessus_ATCC_1997 GPAKPLGPIEQEDYDLGYTFLDENGNPLPMLDENGNVVIDPKTG------
:
TH_3926|M.thermoresistible__bu -----------------------------------------------KNM
Mvan_5711|M.vanbaalenii_PYR-1 -----------------------------------------------ENM
Mflv_1972|M.gilvum_PYR-GCK GRGEDRRYTQHPLEAPIVGADSSVIGDQQARVDAAHESVESAQGALDDAL
MSMEG_5600|M.smegmatis_MC2_155 -----------PLPPPQYAACQQELAFLQG----------------QEAA
Mb0631|M.bovis_AF2122/97 ----------------------------------------------WDTP
Rv0614|M.tuberculosis_H37Rv ----------------------------------------------WDTP
MMAR_0116|M.marinum_M ----------------------------------------------WDTP
MAV_2254|M.avium_104 ----------------------------------------------WDNP
MUL_1136|M.ulcerans_Agy99 ----------------------------------------------PAR-
MAB_0016|M.abscessus_ATCC_1997 -------------------------------------------RPVPDSV
TH_3926|M.thermoresistible__bu VQGVFVGGAIGAAR--------------------GALMGILGGPIGVFG-
Mvan_5711|M.vanbaalenii_PYR-1 VQGVFVGGALGALR--------------------GAVLGVLGGPLGMLG-
Mflv_1972|M.gilvum_PYR-GCK AQSTVAGAGAGPGRDQLDALGHVLFEARGEVTSQTEVLEKLNAAADEVGQ
MSMEG_5600|M.smegmatis_MC2_155 LRARLADFGIHPG----------------EAPSSTSSGGDLTATATQIG-
Mb0631|M.bovis_AF2122/97 DGTPPPGT-GLSPT------------------LQQMILGGDPANLTGQGL
Rv0614|M.tuberculosis_H37Rv DGTPPPGT-GLSPT------------------LQQMILGGDPANLTGQGL
MMAR_0116|M.marinum_M DGTPPPGAPGLSPE------------------LQQMILGGDPANLTGQGL
MAV_2254|M.avium_104 DGAPPAPAPVQPGV------------------IPQLEQSMTAPPAPKPGP
MUL_1136|M.ulcerans_Agy99 LGGPIAGGPVPPGS------------------IPHPVQ----PPHSHHGP
MAB_0016|M.abscessus_ATCC_1997 WGDPADNNADGSPR------------------VPHPPRDHHFADMDANDP
. .
TH_3926|M.thermoresistible__bu -----------GGVLGFVGGAAGGALIS-------------GPARTAVTS
Mvan_5711|M.vanbaalenii_PYR-1 -----------GSVAGFVGGAAGGAMIS-------------GPARTAVTS
Mflv_1972|M.gilvum_PYR-GCK GRVPIPALPENADVQAFPAEPSAFTEGSRALSEGSFGLIPDVAHDIDVFR
MSMEG_5600|M.smegmatis_MC2_155 -----------AEIATFPPGTRADALAERMTGLHLNQADAARATDIAAAR
Mb0631|M.bovis_AF2122/97 A----------DNVQRFVQSLPANDPNTAWLRGQVADLQAHVADIEYART
Rv0614|M.tuberculosis_H37Rv A----------DNVQRFVQSLPANDPNTAWLRGQVADLQAHVADIEYART
MMAR_0116|M.marinum_M L----------DNLQQLVQSLPENDPRTAWLRGQVADLQAHMSDIDYART
MAV_2254|M.avium_104 P----------ASPLPSPSVTPLPNPAAVGPAAAAPAKPPCSPYDATKAI
MUL_1136|M.ulcerans_Agy99 ---------------PVLGKDELPDLGEFNPG------------------
MAB_0016|M.abscessus_ATCC_1997 YRTLPTG----TTVGPNGERIALVSRPPDDPAWAENQTKNGKSVYVTQTE
TH_3926|M.thermoresistible__bu AWDCL---------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 AWDCL---------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK NWSEASSDDRAGAVLDVAGAAPIP-GGKLVTEGLEHAVDAVNAGRHVDDA
MSMEG_5600|M.smegmatis_MC2_155 IWGETG------------GTSKMPDGSIIVLPANIRQTDVMKVFPDGSVT
Mb0631|M.bovis_AF2122/97 HCSTNDWIDRTAQFASGAIVFSIGVLTAETGAGVVAAAAGGVGAATAGVS
Rv0614|M.tuberculosis_H37Rv HCSTNDWIDRTAQFASGAIVFSIGVLTAETGAGVVAAAAGGVGAATAGVS
MMAR_0116|M.marinum_M HCTTSDWFDRTTLFASGLVSTGILTLTAETGVGGVAAVASGFGTLVAGKN
MAV_2254|M.avium_104 LEPPIGMVGILTAVPESLTIAGIPAALTQIGVGTVAVADGLDAADKCLP-
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 AYDVTRQPPQSLGKLQGVDGSKVYQGSIVYDKASGRMYVVGNHGDGSGDT
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK LDAGSAGAHHLPDVPSAPHVDQTPDVGGPHGGGGADAGPVGNFGFEDANA
MSMEG_5600|M.smegmatis_MC2_155 VLRGVDVTQYLPR-------------------------------------
Mb0631|M.bovis_AF2122/97 LLQCLVGSK-----------------------------------------
Rv0614|M.tuberculosis_H37Rv LLQCLVGSK-----------------------------------------
MMAR_0116|M.marinum_M LLGCLVGSK-----------------------------------------
MAV_2254|M.avium_104 --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 ARGMWRSDPVDPNHPN-DWVKTLRYQGDVPSLPGSRESSLVALPHGGVAL
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK LLQSSEANGGHLIERHVGMTSDDLAARMESSGLQTVSTFATADEAASAVS
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
Mb0631|M.bovis_AF2122/97 --------------------------------------------------
Rv0614|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
MAV_2254|M.avium_104 --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 FGADDYAPAEGRNMAVGAISAATPEGLLQARPVTDLLPAGKTPWPGGAPY
TH_3926|M.thermoresistible__bu --------------------------------------------------
Mvan_5711|M.vanbaalenii_PYR-1 --------------------------------------------------
Mflv_1972|M.gilvum_PYR-GCK TALRENQDVLNSWIAEGAPRKLELEAPFDGGAVLVQGATEAVTGSTVRVV
MSMEG_5600|M.smegmatis_MC2_155 --------------------------------------------------
Mb0631|M.bovis_AF2122/97 --------------------------------------------------
Rv0614|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0116|M.marinum_M --------------------------------------------------
MAV_2254|M.avium_104 --------------------------------------------------
MUL_1136|M.ulcerans_Agy99 --------------------------------------------------
MAB_0016|M.abscessus_ATCC_1997 AALPTGVHWDPALRADVVDTRVSIWRDVPG----VRGAYPPVTYQTSVPI
TH_3926|M.thermoresistible__bu ------------------
Mvan_5711|M.vanbaalenii_PYR-1 ------------------
Mflv_1972|M.gilvum_PYR-GCK LKGDGNGGWYVLTGFPKP
MSMEG_5600|M.smegmatis_MC2_155 ------------------
Mb0631|M.bovis_AF2122/97 ------------------
Rv0614|M.tuberculosis_H37Rv ------------------
MMAR_0116|M.marinum_M ------------------
MAV_2254|M.avium_104 ------------------
MUL_1136|M.ulcerans_Agy99 ------------------
MAB_0016|M.abscessus_ATCC_1997 FQPNS-------------