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MAEARRRLSPDDRRNELLALGAEVFGQRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVRAESER LFDATNTPAQPGQTLFTQVRAGVLAYLRYDELHPHGAWAAYMGMSRSDPVLRGIDDHDNDRQANRIIDRV TAGVEPLDAKVERDLRAAVYGWLAFTFEMCRQRLMDASLDADYLGDLCAHALMDALARVPGIPADLAEAV APDRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4802 | - | - | 100% (215) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4672 | - | 5e-11 | 36.19% (105) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1947 | - | 5e-08 | 30.30% (99) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3323 | - | 7e-80 | 65.45% (220) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3295 | - | 7e-80 | 65.45% (220) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 8e-78 | 65.45% (220) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3650 | - | 6e-48 | 45.83% (216) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1239 | - | 1e-78 | 64.55% (220) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4266 | - | 1e-74 | 61.93% (218) | hypothetical protein MAV_4266 |
| M. smegmatis MC2 155 | MSMEG_5424 | - | 5e-10 | 32.35% (102) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0452 | - | 4e-11 | 35.79% (95) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2648 | - | 7e-79 | 64.55% (220) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1640 | - | 1e-102 | 83.80% (216) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4802|M.gilvum_PYR-GCK -------------------------MAEARR--RLSPDDRRNELLALGAE
Mvan_1640|M.vanbaalenii_PYR-1 -------------------------MAGPRR--RLSPDERRSELLTLGAE
MMAR_1239|M.marinum_M -------------------------MATARR--RLSPEDRRAELLALGAE
MUL_2648|M.ulcerans_Agy99 -------------------------MATARR--RLSPEDRRAELLALGAE
Mb3323|M.bovis_AF2122/97 -------------------------MATARR--RLSPQDRRAELLALGAE
Rv3295|M.tuberculosis_H37Rv -------------------------MATARR--RLSPQDRRAELLALGAE
MLBr_00717|M.leprae_Br4923 -------------------------MTTARR--RLSPEDRRAELLALGAE
MAV_4266|M.avium_104 -------------------------MATARR--RLSPEDRRAELLALGAE
MAB_3650|M.abscessus_ATCC_1997 --------------MTDDSDAVRPSGASPRR--RLTPEDRRAELLDFGTQ
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
MSMEG_5424|M.smegmatis_MC2_155 -------------------------MRAPRA--RMTGSERRQQLIEIAKS
* *:. .:** :*: . .
Mflv_4802|M.gilvum_PYR-GCK VFGQRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVRAESERLFD
Mvan_1640|M.vanbaalenii_PYR-1 VFGQRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVRAETERLFH
MMAR_1239|M.marinum_M VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYE
MUL_2648|M.ulcerans_Agy99 VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYE
Mb3323|M.bovis_AF2122/97 VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYA
Rv3295|M.tuberculosis_H37Rv VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYA
MLBr_00717|M.leprae_Br4923 VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYA
MAV_4266|M.avium_104 VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYE
MAB_3650|M.abscessus_ATCC_1997 LFGERHYDDVRMDEVAEQAGVSRALLYRYFPDKRAFYTAVMQAEYDRLYD
TH_0452|M.thermoresistible__bu VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
MSMEG_5424|M.smegmatis_MC2_155 LFAERGYDGTSIEEVAQRANVSKPVVYEHFGGKEGLYAVVVDREMSALLQ
:* .* *. . ::*:*::*.**:.::*.:* .* :: .*: . . *
Mflv_4802|M.gilvum_PYR-GCK ATN-TPAQPGQTLFTQVRAGVLAYLRYDELHPHGAWAAYMGMSRSDPVLR
Mvan_1640|M.vanbaalenii_PYR-1 ATN-TPPQPGQTLFAQVRAGVLAYLQYDEHHPHGAWAAYLGMGRSDPLLR
MMAR_1239|M.marinum_M ATS-IESPVGMTMFEEIRLGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL
MUL_2648|M.ulcerans_Agy99 ATS-IESPVGMTMFEEIRLGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL
Mb3323|M.bovis_AF2122/97 ATN-KAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL
Rv3295|M.tuberculosis_H37Rv ATN-KAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL
MLBr_00717|M.leprae_Br4923 ATN-IPPPAGLTMFEEVRVGVLAYMAYHKQNPEAAWAAYVGLGRSDPVLL
MAV_4266|M.avium_104 NTN-MDDVTGLTMYEEIRVGVLAYMAYHEQNPEAAWAAYVGLGRSDPVLL
MAB_3650|M.abscessus_ATCC_1997 ATISLDMDQTLSGFERLRRTLLVYLHYQEEHPFAPVTVFRMIDSADPTVM
TH_0452|M.thermoresistible__bu GVR-QALRTTTDNRQRLRAAVQAFFDFIEHDGQGYRLIFENDYVTEPQVA
MSMEG_5424|M.smegmatis_MC2_155 GIT--SSLTNNRSRVRVERVALALLTYVEEHTDGFRILIR--DSPAAITS
.:. . : : : . . . .
Mflv_4802|M.gilvum_PYR-GCK GIDDHDNDRQANRIIDRVTAGVEP------LDAKVERD-LRAAVYGWLAF
Mvan_1640|M.vanbaalenii_PYR-1 GIEDIDNDRQANRIIDRITTAVGGG-----IDSKLERD-LRATVYGWLAF
MMAR_1239|M.marinum_M GIDDEAKNRQMEHIMTRIGQVVSGIPGSTALDQHVERD-LRVIIYGWLAF
MUL_2648|M.ulcerans_Agy99 GIDDEAKNRQMEHIMTRIGQVVSGIPGSTALDQHVERD-LRVIIYGWLAF
Mb3323|M.bovis_AF2122/97 GIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERD-LRVIIHGWLAF
Rv3295|M.tuberculosis_H37Rv GIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERD-LRVIIHGWLAF
MLBr_00717|M.leprae_Br4923 GIDDEAKNRQMEHIMSRIGDVVSVVP-ESKLHPDIERD-LRVIVHGWLAF
MAV_4266|M.avium_104 GVEDDAKNRQMEHIMSRINQLLAEVP--ATLEPDVERH-LRVILHGWLAF
MAB_3650|M.abscessus_ATCC_1997 AIEQQEYDKQTDRIMAVVDHVAGD-----EMTPALVTD-LKVVIRAWLAF
TH_0452|M.thermoresistible__bu AQVKVATEACTDAVFDLISQ-----------DSGLEAHRARMIAVGLVAI
MSMEG_5424|M.smegmatis_MC2_155 GTYATLLNDAVNQVSSILAGDFS--------RRGLDPDLAPLYAQALVGS
. : : : : : . . :.
Mflv_4802|M.gilvum_PYR-GCK TFEMCRQRLMDASLDADYLGDLCAHALMDALARVPGIPADLAEAVAPDRR
Mvan_1640|M.vanbaalenii_PYR-1 TFEMCRQRLMDASLDADFIAGLCAHGLMDAVGRVPGIPAALAEAVAVDRR
MMAR_1239|M.marinum_M TFEICRQRIMDPGTDADRLADACAHTLLDSIARVPEIPGELAEAMATARH
MUL_2648|M.ulcerans_Agy99 TFEICRQRIMDPGTDADRLADACAHTLLDSIARVPEIPGELAEAMATARH
Mb3323|M.bovis_AF2122/97 TFELCRQRIMDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM
Rv3295|M.tuberculosis_H37Rv TFELCRQRIMDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM
MLBr_00717|M.leprae_Br4923 TFEVCRQRIMDPSTDADRLADSCAHALLDAIARVPEISKELADAMAIARQ
MAV_4266|M.avium_104 TFEICRQRIIDPTTDADKLADACAHALLDAIGRVPEIPEELGEAMANSRL
MAB_3650|M.abscessus_ATCC_1997 NQELARQRALNPELDVDWLADTSAHAMIDAVRRMPNIPQAVVDLMGAD--
TH_0452|M.thermoresistible__bu SVDCARYWLHADRPISK--EDAVEGTVQFAWGGLSHVPLTRS--------
MSMEG_5424|M.smegmatis_MC2_155 VSMTAQWWLDVREPSKEVVAAHVVNLAWNGLTHLESNPVLHEE-------
.: . . : .
Mflv_4802|M.gilvum_PYR-GCK ---
Mvan_1640|M.vanbaalenii_PYR-1 ---
MMAR_1239|M.marinum_M TPQ
MUL_2648|M.ulcerans_Agy99 TPQ
Mb3323|M.bovis_AF2122/97 ---
Rv3295|M.tuberculosis_H37Rv ---
MLBr_00717|M.leprae_Br4923 PPQ
MAV_4266|M.avium_104 ---
MAB_3650|M.abscessus_ATCC_1997 ---
TH_0452|M.thermoresistible__bu ---
MSMEG_5424|M.smegmatis_MC2_155 ---