For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
ARSPAARRPPGGNQERAERTRRTVIDETVRYILDEGFAAPSVRRITERAGLTWGVVQYHFGDLGGLLMAV VDQGIAELTGALERLRTETANLPAEHRTEVVVDALWQAFSSPTSMAALEILISTRAARDSDVNAQLVDTM RQFTELGRHLGEDLDAPQATEIGNLIWATLRGIVLAQMVSPQPLDTSRDRRTLVDVLNTYMRAKGR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_0925 | - | - | 100% (207) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2752 | - | 1e-09 | 24.75% (198) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4816 | - | 5e-08 | 22.70% (163) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 9e-10 | 26.63% (199) | TetR/ACRR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 7e-10 | 26.63% (199) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2952c | - | 8e-12 | 29.35% (184) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1934 | - | 2e-11 | 25.93% (216) | hypothetical protein MMAR_1934 |
| M. avium 104 | MAV_4851 | - | 4e-44 | 47.09% (189) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0735 | - | 1e-11 | 26.39% (216) | putative transcriptional regulator |
| M. thermoresistible (build 8) | TH_2354 | - | 7e-13 | 25.57% (219) | putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2160 | - | 5e-11 | 25.35% (213) | hypothetical protein MUL_2160 |
| M. vanbaalenii PYR-1 | Mvan_3785 | - | 2e-09 | 24.52% (208) | hypothetical protein Mvan_3785 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0925|M.gilvum_PYR-GCK ----------------MARSPAARRPPG------GNQERAERTRRTVIDE
MAV_4851|M.avium_104 --------------MSIAAGQQPGRPAGPTRRTTAPRKRGDDTRARIIDE
MMAR_1934|M.marinum_M ----------------MTRAGVAGRRP---------NRRGNATRESMLEA
MUL_2160|M.ulcerans_Agy99 ----------------MTRAGVAGRRP---------NRRGNATRESMIEA
Mvan_3785|M.vanbaalenii_PYR-1 ----------------MTEAAAPARRP---------NRRGQATRANMLEA
MSMEG_0735|M.smegmatis_MC2_155 ----------------MTDAAQPGSGPR-AERPNRPNRRGLATRENMLEA
TH_2354|M.thermoresistible__bu ---------MPGVSVLKSPGGPPGARP--AEVPRRANRRGQATRENMLEA
Mb0310|M.bovis_AF2122/97 -------------------MGVPAKKK---------QQQGERSRESILDA
Rv0302|M.tuberculosis_H37Rv -------------------MGVPAKKK---------QQQGERSRESILDA
MAB_2952c|M.abscessus_ATCC_199 MYARKNAKVIALGGWSVVVANLEGRASR-----RTQAQRSAEMRTRLLDA
.:. * :::
Mflv_0925|M.gilvum_PYR-GCK TVRYILDEGFAAPSVRRITERAGLTWGVVQYHFGDLGGLLMAVVDQGIAE
MAV_4851|M.avium_104 TVRCIIEEGFAAATAKHVAERAGVTWGVIQYHFGDRNGLLMAVVDDGVAR
MMAR_1934|M.marinum_M ALTSLASGDPGSVSANRIAKEIGATWGAVQYQFGDVDGFWAAVLHRTAER
MUL_2160|M.ulcerans_Agy99 ALTSLASGDPGSVSANRIAKAIGATWGAVQYQFGDADGFWAAVLHRTAER
Mvan_3785|M.vanbaalenii_PYR-1 ALKSLASGDPGSVSANRIAKDIGATWGAVQYQFGDADGFWAAVLHRTAER
MSMEG_0735|M.smegmatis_MC2_155 ALQALATGDPGAVSANRIAKQIGATWGAVKYQFGDIDGLWAAVLHRTAER
TH_2354|M.thermoresistible__bu ALAALATGDPGAVSANRIAKQIGVTWGAVKYQFGDIDGLWAAVLRRTAER
Mb0310|M.bovis_AF2122/97 TERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQR
Rv0302|M.tuberculosis_H37Rv TERLMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQR
MAB_2952c|M.abscessus_ATCC_199 TVECLVAHGYAGTTTPRIAEMAGVTRGAQAYHFQSKEDLVVAAIEHLAQQ
: : . .. : : . * : . ::* . .. * : .
Mflv_0925|M.gilvum_PYR-GCK LT-GALERLRTETANLPAEHRTEVVVDALWQAFSSPTSMAALEILISTRA
MAV_4851|M.avium_104 LV-ESLS--SADVSELPLRQRVEVVIDTAWSCYSSPTSMAAFEILHATRG
MMAR_1934|M.marinum_M RAGSMLALSKPLQSGRPLQERVAAVIETLFHGLASADSR-AIENLRAALP
MUL_2160|M.ulcerans_Agy99 RAGSMLALSKPLQSGRPLQERVAAVIETLFHGLASADSR-AIENLRAALP
Mvan_3785|M.vanbaalenii_PYR-1 RA-DVFASVDPDAS---LRDRVASIIDTLYDGLAEPDSR-AIENLRAALP
MSMEG_0735|M.smegmatis_MC2_155 RA-GVLGRHDPGAP---LRQRVAGIIDMLYDGLTASDSR-AIENLRAALP
TH_2354|M.thermoresistible__bu RA-GVIGRHDAGAP---LRERVAGIIDMLYDGLTASDSR-AIENLRAALP
Mb0310|M.bovis_AF2122/97 FFAAIPTWDEAHGP---VEQRSERQLTELVSLQSQHPDFLRLFYLLSMER
Rv0302|M.tuberculosis_H37Rv FFAAIPTWDEAHGP---VEQRSERQLTELVSLQSQHPDFLRLFYLLSMER
MAB_2952c|M.abscessus_ATCC_199 RTQAAIREIARLQG---NPDPVSAVLDFMWEIHQGPIFVATMELWIASR-
. : : :
Mflv_0925|M.gilvum_PYR-GCK ARDSDVNAQLVDTMRQFTELGR---------HLGEDLDAPQATEIGNLIW
MAV_4851|M.avium_104 ALGDSSRRHLLDMNAAIGQLGR---------LITTD---PANAGVAEVIW
MMAR_1934|M.marinum_M RDPGELERLYPRTAAELFSWGRSWLETCQNAFADLDVDPNRVREVAALIP
MUL_2160|M.ulcerans_Agy99 RDPGELERLYPRTAAELFSWGRSWLETCQNAFANLDVDPNRVREVAALIP
Mvan_3785|M.vanbaalenii_PYR-1 RDPAELERLYPQTAAELFSWGQSWLQICHNAFAGLGVDPDRVREVATLIP
MSMEG_0735|M.smegmatis_MC2_155 RDRAELERLYPRTAAELSSWGQGWLATCQQAFADLDVDPERVREVASFIP
TH_2354|M.thermoresistible__bu RDRAELERLYPRTAAELSSWGEGWLQTCQQAFADLDVDPERVAEVASFIP
Mb0310|M.bovis_AF2122/97 SQDPVVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAV
Rv0302|M.tuberculosis_H37Rv SQDPAVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAV
MAB_2952c|M.abscessus_ATCC_199 -----TDKVLAQQIQRMEPFVNSALAAAIVQLLPEHPAPAELAKIVYTAM
. :
Mflv_0925|M.gilvum_PYR-GCK ATLRGIVLAQMVSPQPLDTSRDRRTLVDVLNTYMRAKGR------
MAV_4851|M.avium_104 ATLRGVVLAQMVIGTTVDWSLERRALIDMVTRVLQ----------
MMAR_1934|M.marinum_M GAMRGLVSERQLG-SYADLELARRALTNALAGYLKNSRTP-----
MUL_2160|M.ulcerans_Agy99 GAMRGLVSERQLG-SYADLELARRALTNALAGYLKNSRTP-----
Mvan_3785|M.vanbaalenii_PYR-1 GAMRGLVSERQLG-SYADLDVARRGLTNALVAYLQAAD-------
MSMEG_0735|M.smegmatis_MC2_155 GAMRGITSERQLG-TYTDLDVARRGLTNAIVSYLEDNGSGRRE--
TH_2354|M.thermoresistible__bu GAMRGITSERQLG-TYIDLELARRGLTNAIVSYLEDRGPGEKSNQ
Mb0310|M.bovis_AF2122/97 ALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET----
Rv0302|M.tuberculosis_H37Rv ALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET----
MAB_2952c|M.abscessus_ATCC_199 DTLRGILIASFVDGDVERARRRWARASAHLRAVAVAAFPSLG---
*: : :