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MTLDVKGDGLGAQVTGVDPKNLDSISTAEIRKIVYVNKLVVLKDVHPTPEEFIKLGRIIGEIVPYYEPIY RHKDYPEIFVSSTEEGQGVPNTGAFWHVDYIFMPEPFAFSMTLPLAMPGHDRGTHFIDLSQVWESLPNAM KDSVRGTYSNHSPRRYIKIRPSDVYRPVGEVLAEIEEVTPPQKWPTVIKHPKTGQEILYICEAATVSVED KNGNLLDPMVLQELLTASGQLDPDCKSLLIHTQHYEVGDVVLWDNRALVHRAKHGTVSGTLITYRLTLLD GLKTPGYAV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01992 | - | - | 100% (289) | putative oxidoreductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0100 | - | 1e-136 | 76.39% (288) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_2472 | - | 1e-08 | 24.91% (273) | taurine catabolism dioxygenase TauD/TfdA |
| M. tuberculosis H37Rv | Rv0097 | - | 1e-136 | 76.39% (288) | oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0659 | - | 1e-136 | 76.74% (288) | putative dioxygenase |
| M. marinum M | MMAR_0260 | - | 1e-134 | 74.91% (287) | oxidoreductase |
| M. avium 104 | MAV_0235 | - | 3e-15 | 24.35% (308) | taurine catabolism dioxygenase TauD/TfdA |
| M. smegmatis MC2 155 | MSMEG_0181 | - | 4e-11 | 23.84% (281) | alpha-ketoglutarate-dependent taurine dioxygenase |
| M. thermoresistible (build 8) | TH_0024 | - | 9e-06 | 23.64% (275) | dioxygenase, TauD/TfdA family protein |
| M. ulcerans Agy99 | MUL_4854 | - | 1e-133 | 74.22% (287) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4182 | - | 3e-11 | 26.45% (276) | taurine catabolism dioxygenase TauD/TfdA |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0100|M.bovis_AF2122/97 ------------------------------------------MTLKVKGE
Rv0097|M.tuberculosis_H37Rv ------------------------------------------MTLKVKGE
MMAR_0260|M.marinum_M ------------------------------------------MTLNVKGE
MUL_4854|M.ulcerans_Agy99 ------------------------------------------MTLNVKGE
MAB_0659|M.abscessus_ATCC_1997 ------------------------------------------MTLNVKGE
MLBr_01992|M.leprae_Br4923 ------------------------------------------MTLDVKGD
Mflv_2472|M.gilvum_PYR-GCK ---------------------------------------MSLLTINKLTP
TH_0024|M.thermoresistible__bu ---------------------------------------MSRLTINRLTA
Mvan_4182|M.vanbaalenii_PYR-1 ---------------------------------------MTLLTINKLTS
MAV_0235|M.avium_104 ------------------------------------------MEIVASGP
MSMEG_0181|M.smegmatis_MC2_155 MTDTRHAPPPAPRPIPEYDVSAGPFSHLAAERDRLAALRWRHFDAEQVGT
:
Mb0100|M.bovis_AF2122/97 GLGAQVTGVDPKNLDDIT--TDEIRDIVYTNKLVVLKDVHPSPREFIKLG
Rv0097|M.tuberculosis_H37Rv GLGAQVTGVDPKNLDDIT--TDEIRDIVYTNKLVVLKDVHPSPREFIKLG
MMAR_0260|M.marinum_M GLGAQITGVDPKNLDDIT--TDEIRDIVYANKLVILKDVNPSPEEFLKLG
MUL_4854|M.ulcerans_Agy99 GLGAQITGVDPKILDDIT--TDEIRDIVYANKLVILKDVNPSPEEFLKLG
MAB_0659|M.abscessus_ATCC_1997 GLGAQVTGIDPGNLDGIT--TEEIRELVYRHKLVVLKGVHPTPEQFIELG
MLBr_01992|M.leprae_Br4923 GLGAQVTGVDPKNLDSIS--TAEIRKIVYVNKLVVLKDVHPTPEEFIKLG
Mflv_2472|M.gilvum_PYR-GCK SVGAEVLGVDPVRLASDESLAAAVLDALEDNGVLVFPDLHLAPEAQVAFS
TH_0024|M.thermoresistible__bu SVGAEVTGTTADELAADAALGAAVLDALEEHGVLVFRGLRIDPQTQVKFC
Mvan_4182|M.vanbaalenii_PYR-1 SVGAEVTGLDPGRLAGDDALGTAVLDALEDNGVLVFPGLHLEPEVQVEFC
MAV_0235|M.avium_104 GFAAELRGVTIADVAASPDVYAQVRAAFEEHSVLVFRDQHVSDEAQLAFS
MSMEG_0181|M.smegmatis_MC2_155 TLGAQISGVDLTRPLAGA-VFDELRTALHEYKVLFFRDQPMSADAHAALA
..*:: * : . ::.: . :
Mb0100|M.bovis_AF2122/97 RIIGQIVPYYEPMYHHEDHPEIFVSSTEEGQ---GVPKTGAFWHIDYMFM
Rv0097|M.tuberculosis_H37Rv RIIGQIVPYYEPMYHHEDHPEIFVSSTEEGQ---GVPKTGAFWHIDYMFM
MMAR_0260|M.marinum_M KIVGQIVPYYEPMYHHEDHPEIFVSSTEEGQ---GVPKTGAFWHIDYMFM
MUL_4854|M.ulcerans_Agy99 KIVGQIVPYYEPMYHHEDHPEIFVSSTVEGQ---GVPKTGAFWHIDYMFM
MAB_0659|M.abscessus_ATCC_1997 RLIGEIVPYYEPVYHHQDHPEIFVSSTEEGQ---GVPRTGAFWHVDYMFM
MLBr_01992|M.leprae_Br4923 RIIGEIVPYYEPIYRHKDYPEIFVSSTEEGQ---GVPNTGAFWHVDYIFM
Mflv_2472|M.gilvum_PYR-GCK RRLGAVDHSADG--HHPVAGIYPVTLDKSKNASAAYLRATFDWHIDGCTP
TH_0024|M.thermoresistible__bu RHLGEVDHSSDG--HHPVAGIYPVTLDKSKNSSAAYLRATFDWHIDGCTP
Mvan_4182|M.vanbaalenii_PYR-1 RRLGEIDFSSDG--HHRVAGIYPVTLDKSKNSSAAYLRATFDWHIDGCTP
MAV_0235|M.avium_104 RRFGPLGVTKVGAVGHGSHLVVLKTLDDDGNVVPADHRLALENKANQLWH
MSMEG_0181|M.smegmatis_MC2_155 RQFGPLEVHPLLPANSAES--ALARFQKDAN----VSGYENAWHHDVTWR
: .* : . : : :
Mb0100|M.bovis_AF2122/97 PE------PFAFSMVLPLAVPGHDRGTYFIDLARVWQSLPAAKRDPARGT
Rv0097|M.tuberculosis_H37Rv PE------PFAFSMVLPLAVPGHDRGTYFIDLARVWQSLPAAKRDPARGT
MMAR_0260|M.marinum_M PE------PFAFSMVLPLAVPGHDRGTYFIDLAKVWQSLPAAQQAPARGT
MUL_4854|M.ulcerans_Agy99 PE------PFAFSMVLPLAVPGHDRGTYFIDLAKVWQSLPSAQQAPARGT
MAB_0659|M.abscessus_ATCC_1997 PK------PFAFSMVLPLAVPGHDRGTYFIDLSKVWESLPAKTKDAALGT
MLBr_01992|M.leprae_Br4923 PE------PFAFSMTLPLAMPGHDRGTHFIDLSQVWESLPNAMKDSVRGT
Mflv_2472|M.gilvum_PYR-GCK IG---DECPQRATVLSAVQVADRGGETEFANSYAAYEAFSDEEKERYAAL
TH_0024|M.thermoresistible__bu TG---DEYPQKATVLSAVQVADRGGETEFASSYGAYEALSEEEKRHVETL
Mvan_4182|M.vanbaalenii_PYR-1 TG---DDYPQMATVLSAKQVAESGGETEFASSYAAYDALTDAEKQRFASL
MAV_0235|M.avium_104 TDSSFKRVPALASVLSSRIVPGRGGETEYVSTRIAFERLDPGLRERVENS
MSMEG_0181|M.smegmatis_MC2_155 PE------PSILAILHAIEVPPIGGDTLFADMYAAYDSLDDETKAEIDRL
* :: . :. . * : . .:: : :
Mb0100|M.bovis_AF2122/97 VSTHDPRRHIKIRPSDVYRPIGEVWDEINRTTPPIKWPTVIRHPKTGQEI
Rv0097|M.tuberculosis_H37Rv VSTHDPRRHIKIRPSDVYRPIGEVWDEINRTTPPIKWPTVIRHPKTGQEI
MMAR_0260|M.marinum_M LSTHDPRRHIKIRPSDVYRPIGEVWDEISRATPPIKWPTVIRHPKTGEEI
MUL_4854|M.ulcerans_Agy99 LSTHDPRRHIKIRPSDVYRPIGEVWDEISRATPPIKWPTVIRHPKTGEEI
MAB_0659|M.abscessus_ATCC_1997 FSTHTPRRYIKIRPSDVYRPIGEILAEIERTTPPQKWPTVIKHPKTGEEI
MLBr_01992|M.leprae_Br4923 YSNHSPRRYIKIRPSDVYRPVGEVLAEIEEVTPPQKWPTVIKHPKTGQEI
Mflv_2472|M.gilvum_PYR-GCK RVVHS----LEASQSRVNPDPSPEELARWRSRPTHEHPLVWTHRS-GRKS
TH_0024|M.thermoresistible__bu RVVHS----LEASQRRVTPDPTPEQLARWRARPTHEHPLVWTHRN-GRKS
Mvan_4182|M.vanbaalenii_PYR-1 RVVHS----LEASQRRVNPDPSPEELARWRARPTHEHPLVWTHRT-GRKS
MAV_0235|M.avium_104 FAWHE----YAYSRGKIAPDLARPEER--AALPPQCWRLVWRNPVNGRKA
MSMEG_0181|M.smegmatis_MC2_155 DAAHD----FTYYLRGLVPD--EKIAELQAAHPPVTHPVVCTHPITGRRH
* : *. * : *..
Mb0100|M.bovis_AF2122/97 LYICATGTTKIEDKDGNPVDPEVLQELMAATGQLDPEYQSPFIHTQHYQV
Rv0097|M.tuberculosis_H37Rv LYICATGTTKIEDKDGNPVDPEVLQELMAATGQLDPEYQSPFIHTQHYQV
MMAR_0260|M.marinum_M LYICATGTTKIEDKDGNLVDPAVLAELLAATGQLDPEYNSPFIHTQHYEV
MUL_4854|M.ulcerans_Agy99 LYICATGTTKIEDKDGNLVDPAVLAELLAATGQLDPEYNSPFIHTQHYEV
MAB_0659|M.abscessus_ATCC_1997 LYICEAGTETIEDGAGRIQDAALLQQLLEASGQLDPDYASPFIHAQHYEV
MLBr_01992|M.leprae_Br4923 LYICEAATVSVEDKNGNLLDPMVLQELLTASGQLDPDCKSLLIHTQHYEV
Mflv_2472|M.gilvum_PYR-GCK LVLGASAHYVVG------MDYDEGRALLAEL--LDRATQPELVYSHSWSV
TH_0024|M.thermoresistible__bu LVLGASADYVVG------MDLDEGRALLADL--LDRATTEDRVYRHRWSV
Mvan_4182|M.vanbaalenii_PYR-1 LVLGASADYIVG------MDPEEGRALLSEL--LDRATTADKVYSHHWAV
MAV_0235|M.avium_104 LYLASHAYGIEG------MEPAAARELLAAL--TEAATAPGASYLHSWRA
MSMEG_0181|M.smegmatis_MC2_155 LYVNRMFVSHIAG-----YPHDTGRALLDRL--CRTADAPEHQVRFRWAP
* : *: :
Mb0100|M.bovis_AF2122/97 GDIILWDNRVLMHRAKHGSAAGTLTTYRLTMLDGLKTPGYAA--------
Rv0097|M.tuberculosis_H37Rv GDIILWDNRVLMHRAKHGSAAGTLTTYRLTMLDGLKTPGYAA--------
MMAR_0260|M.marinum_M GDIILWDNRVLMHRAKHGTASGTLTTYRLTMLDGLETPGYPA--------
MUL_4854|M.ulcerans_Agy99 GDIILWDNRVLMHRAKHGTASGTLTTYRLTMLDGLETPGYPA--------
MAB_0659|M.abscessus_ATCC_1997 GDIVLWDNRSLVHRAKHGTASGTLTTYRLTMLDGLEAPGFAA--------
MLBr_01992|M.leprae_Br4923 GDVVLWDNRALVHRAKHGTVSGTLITYRLTLLDGLKTPGYAV--------
Mflv_2472|M.gilvum_PYR-GCK GDTVIWDNNGVLHRAAPYDPDSQREMLRTTVLGDEPIQ------------
TH_0024|M.thermoresistible__bu GDTVIWDNRGVLHRAAPYPEDSPREMLRTTVLGDEPIQ------------
Mvan_4182|M.vanbaalenii_PYR-1 GDTVIWDNRGVLHRAARYDENSPREMLRTTVLGDEPIQ------------
MAV_0235|M.avium_104 GDVVMWDNRATMHRGRPWPAHQPRCMVRSTIAATAADGLEAMYPPWHAVA
MSMEG_0181|M.smegmatis_MC2_155 DSVAIWDNRAVQHYAASGYWPHTRIMERASVTGPVPCR------------
.. :***. * . * ::
Mb0100|M.bovis_AF2122/97 -
Rv0097|M.tuberculosis_H37Rv -
MMAR_0260|M.marinum_M -
MUL_4854|M.ulcerans_Agy99 -
MAB_0659|M.abscessus_ATCC_1997 -
MLBr_01992|M.leprae_Br4923 -
Mflv_2472|M.gilvum_PYR-GCK -
TH_0024|M.thermoresistible__bu -
Mvan_4182|M.vanbaalenii_PYR-1 -
MAV_0235|M.avium_104 R
MSMEG_0181|M.smegmatis_MC2_155 -