For questions or suggestions e-mail us at: ioerger@cs.tamu.edu

M. bovis AF2122 / 97 Mb0100 (-)

annotation: oxidoreductase
coordinates: 106770 - 107639
length: 289

MTLKVKGEGLGAQVTGVDPKNLDDITTDEIRDIVYTNKLVVLKDVHPSPREFIKLGRIIGQIVPYYEPMY
HHEDHPEIFVSSTEEGQGVPKTGAFWHIDYMFMPEPFAFSMVLPLAVPGHDRGTYFIDLARVWQSLPAAK
RDPARGTVSTHDPRRHIKIRPSDVYRPIGEVWDEINRTTPPIKWPTVIRHPKTGQEILYICATGTTKIED
KDGNPVDPEVLQELMAATGQLDPEYQSPFIHTQHYQVGDIILWDNRVLMHRAKHGSAAGTLTTYRLTMLD
GLKTPGYAA
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0100--100% (289)oxidoreductase
M. bovis AF2122 / 97Mb3440-3e-0923.97% (267) dioxygenase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCK-----
M. tuberculosis H37RvRv0097-1e-174100.00% (289) oxidoreductase
M. leprae Br4923MLBr_01992-1e-13676.39% (288) putative oxidoreductase
M. abscessus ATCC 19977MAB_0659-1e-13876.82% (289) putative dioxygenase
M. marinum MMMAR_0260-1e-16190.66% (289) oxidoreductase
M. avium 104MAV_0235-2e-1624.17% (302) taurine catabolism dioxygenase TauD/TfdA
M. smegmatis MC2 155MSMEG_0181-9e-1325.75% (268) alpha-ketoglutarate-dependent taurine dioxygenase
M. thermoresistible (build 8)-----
M. ulcerans Agy99MUL_4854-1e-15989.62% (289) oxidoreductase
M. vanbaalenii PYR-1-----

CLUSTAL 2.0.9 multiple sequence alignment


Mb0100|M.bovis_AF2122/97            ------------------------------------------MTLKVKGE
Rv0097|M.tuberculosis_H37Rv         ------------------------------------------MTLKVKGE
MMAR_0260|M.marinum_M               ------------------------------------------MTLNVKGE
MUL_4854|M.ulcerans_Agy99           ------------------------------------------MTLNVKGE
MAB_0659|M.abscessus_ATCC_1997      ------------------------------------------MTLNVKGE
MLBr_01992|M.leprae_Br4923          ------------------------------------------MTLDVKGD
MAV_0235|M.avium_104                ------------------------------------------MEIVASGP
MSMEG_0181|M.smegmatis_MC2_155      MTDTRHAPPPAPRPIPEYDVSAGPFSHLAAERDRLAALRWRHFDAEQVGT
                                                                              :     * 

Mb0100|M.bovis_AF2122/97            GLGAQVTGVDPKNLDDIT--TDEIRDIVYTNKLVVLKDVHPSPREFIKLG
Rv0097|M.tuberculosis_H37Rv         GLGAQVTGVDPKNLDDIT--TDEIRDIVYTNKLVVLKDVHPSPREFIKLG
MMAR_0260|M.marinum_M               GLGAQITGVDPKNLDDIT--TDEIRDIVYANKLVILKDVNPSPEEFLKLG
MUL_4854|M.ulcerans_Agy99           GLGAQITGVDPKILDDIT--TDEIRDIVYANKLVILKDVNPSPEEFLKLG
MAB_0659|M.abscessus_ATCC_1997      GLGAQVTGIDPGNLDGIT--TEEIRELVYRHKLVVLKGVHPTPEQFIELG
MLBr_01992|M.leprae_Br4923          GLGAQVTGVDPKNLDSIS--TAEIRKIVYVNKLVVLKDVHPTPEEFIKLG
MAV_0235|M.avium_104                GFAAELRGVTIADVAASPDVYAQVRAAFEEHSVLVFRDQHVSDEAQLAFS
MSMEG_0181|M.smegmatis_MC2_155      TLGAQISGVDLTRPLAGA-VFDELRTALHEYKVLFFRDQPMSADAHAALA
                                     :.*:: *:        .    ::*  .   .::.::.   :      :.

Mb0100|M.bovis_AF2122/97            RIIGQIVPYYEPMYHHEDHPEIFVSSTEEGQGVP---------KTGAFWH
Rv0097|M.tuberculosis_H37Rv         RIIGQIVPYYEPMYHHEDHPEIFVSSTEEGQGVP---------KTGAFWH
MMAR_0260|M.marinum_M               KIVGQIVPYYEPMYHHEDHPEIFVSSTEEGQGVP---------KTGAFWH
MUL_4854|M.ulcerans_Agy99           KIVGQIVPYYEPMYHHEDHPEIFVSSTVEGQGVP---------KTGAFWH
MAB_0659|M.abscessus_ATCC_1997      RLIGEIVPYYEPVYHHQDHPEIFVSSTEEGQGVP---------RTGAFWH
MLBr_01992|M.leprae_Br4923          RIIGEIVPYYEPIYRHKDYPEIFVSSTEEGQGVP---------NTGAFWH
MAV_0235|M.avium_104                RRFGPLGVTKVGAVGHGSHLVVLKTLDDDGNVVPADHRLALENKANQLWH
MSMEG_0181|M.smegmatis_MC2_155      RQFGPLEVH--PLLPANSAESALARFQKDANVSG----------YENAWH
                                    : .* :           .    :     :.:                 **

Mb0100|M.bovis_AF2122/97            IDYMFMPEPFAFSMVLPLAVPGHDRGTYFIDLARVWQSLPAAKRDPARGT
Rv0097|M.tuberculosis_H37Rv         IDYMFMPEPFAFSMVLPLAVPGHDRGTYFIDLARVWQSLPAAKRDPARGT
MMAR_0260|M.marinum_M               IDYMFMPEPFAFSMVLPLAVPGHDRGTYFIDLAKVWQSLPAAQQAPARGT
MUL_4854|M.ulcerans_Agy99           IDYMFMPEPFAFSMVLPLAVPGHDRGTYFIDLAKVWQSLPSAQQAPARGT
MAB_0659|M.abscessus_ATCC_1997      VDYMFMPKPFAFSMVLPLAVPGHDRGTYFIDLSKVWESLPAKTKDAALGT
MLBr_01992|M.leprae_Br4923          VDYIFMPEPFAFSMTLPLAMPGHDRGTHFIDLSQVWESLPNAMKDSVRGT
MAV_0235|M.avium_104                TDSSFKRVPALASVLSSRIVPGRGGETEYVSTRIAFERLDPGLRERVENS
MSMEG_0181|M.smegmatis_MC2_155      HDVTWRPEPSILAILHAIEVPPIGGDTLFADMYAAYDSLDDETKAEIDRL
                                     *  :   *   ::  .  :*  .  * : .   .:: *    :      

Mb0100|M.bovis_AF2122/97            VSTHDPRRHIKIRPSDVYRPIGEVWDEINRTTPPIKWPTVIRHPKTGQEI
Rv0097|M.tuberculosis_H37Rv         VSTHDPRRHIKIRPSDVYRPIGEVWDEINRTTPPIKWPTVIRHPKTGQEI
MMAR_0260|M.marinum_M               LSTHDPRRHIKIRPSDVYRPIGEVWDEISRATPPIKWPTVIRHPKTGEEI
MUL_4854|M.ulcerans_Agy99           LSTHDPRRHIKIRPSDVYRPIGEVWDEISRATPPIKWPTVIRHPKTGEEI
MAB_0659|M.abscessus_ATCC_1997      FSTHTPRRYIKIRPSDVYRPIGEILAEIERTTPPQKWPTVIKHPKTGEEI
MLBr_01992|M.leprae_Br4923          YSNHSPRRYIKIRPSDVYRPVGEVLAEIEEVTPPQKWPTVIKHPKTGQEI
MAV_0235|M.avium_104                FAWHEYAYSRGKIAPDLARPE------ERAALPPQCWRLVWRNPVNGRKA
MSMEG_0181|M.smegmatis_MC2_155      DAAHDFTYYLRGLVPDE------KIAELQAAHPPVTHPVVCTHPITGRRH
                                     : *          .*              . **     *  :* .*.. 

Mb0100|M.bovis_AF2122/97            LYICATGTTKIEDKDGNPVDPEVLQELMAATGQLDPEYQSPFIHTQHYQV
Rv0097|M.tuberculosis_H37Rv         LYICATGTTKIEDKDGNPVDPEVLQELMAATGQLDPEYQSPFIHTQHYQV
MMAR_0260|M.marinum_M               LYICATGTTKIEDKDGNLVDPAVLAELLAATGQLDPEYNSPFIHTQHYEV
MUL_4854|M.ulcerans_Agy99           LYICATGTTKIEDKDGNLVDPAVLAELLAATGQLDPEYNSPFIHTQHYEV
MAB_0659|M.abscessus_ATCC_1997      LYICEAGTETIEDGAGRIQDAALLQQLLEASGQLDPDYASPFIHAQHYEV
MLBr_01992|M.leprae_Br4923          LYICEAATVSVEDKNGNLLDPMVLQELLTASGQLDPDCKSLLIHTQHYEV
MAV_0235|M.avium_104                LYLASHAYG-IEG-----MEPAAARELLAALTEAATAPGASYLHS--WRA
MSMEG_0181|M.smegmatis_MC2_155      LYVNRMFVSHIAG-----YPHDTGRALLDRLCRTADAPEHQVRFR--WAP
                                    **:       : .             *:    .          .   :  

Mb0100|M.bovis_AF2122/97            GDIILWDNRVLMHRAKHGSAAG-------TLTTYRLTMLDGLKTPGYAA-
Rv0097|M.tuberculosis_H37Rv         GDIILWDNRVLMHRAKHGSAAG-------TLTTYRLTMLDGLKTPGYAA-
MMAR_0260|M.marinum_M               GDIILWDNRVLMHRAKHGTASG-------TLTTYRLTMLDGLETPGYPA-
MUL_4854|M.ulcerans_Agy99           GDIILWDNRVLMHRAKHGTASG-------TLTTYRLTMLDGLETPGYPA-
MAB_0659|M.abscessus_ATCC_1997      GDIVLWDNRSLVHRAKHGTASG-------TLTTYRLTMLDGLEAPGFAA-
MLBr_01992|M.leprae_Br4923          GDVVLWDNRALVHRAKHGTVSG-------TLITYRLTLLDGLKTPGYAV-
MAV_0235|M.avium_104                GDVVMWDNRATMHRGRPWPAHQPRCMVRSTIAATAADGLEAMYPPWHAVA
MSMEG_0181|M.smegmatis_MC2_155      DSVAIWDNRAVQHYAASG-----------YWPHTRIMERASVTGPVPCR-
                                    ..: :****   * .                         .:  *     

Mb0100|M.bovis_AF2122/97            -
Rv0097|M.tuberculosis_H37Rv         -
MMAR_0260|M.marinum_M               -
MUL_4854|M.ulcerans_Agy99           -
MAB_0659|M.abscessus_ATCC_1997      -
MLBr_01992|M.leprae_Br4923          -
MAV_0235|M.avium_104                R
MSMEG_0181|M.smegmatis_MC2_155      -