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MTLNVKGEGLGAQVTGIDPGNLDGITTEEIRELVYRHKLVVLKGVHPTPEQFIELGRLIGEIVPYYEPVY HHQDHPEIFVSSTEEGQGVPRTGAFWHVDYMFMPKPFAFSMVLPLAVPGHDRGTYFIDLSKVWESLPAKT KDAALGTFSTHTPRRYIKIRPSDVYRPIGEILAEIERTTPPQKWPTVIKHPKTGEEILYICEAGTETIED GAGRIQDAALLQQLLEASGQLDPDYASPFIHAQHYEVGDIVLWDNRSLVHRAKHGTASGTLTTYRLTMLD GLEAPGFAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0659 | - | - | 100% (289) | putative dioxygenase |
| M. abscessus ATCC 19977 | MAB_0086 | - | 2e-12 | 22.50% (280) | putative taurine dioxygenase |
| M. abscessus ATCC 19977 | MAB_3621c | - | 4e-08 | 23.05% (243) | taurine dioxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0100 | - | 1e-138 | 76.82% (289) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_3107 | - | 4e-10 | 22.93% (266) | taurine dioxygenase |
| M. tuberculosis H37Rv | Rv0097 | - | 1e-138 | 76.82% (289) | oxidoreductase |
| M. leprae Br4923 | MLBr_01992 | - | 1e-136 | 76.74% (288) | putative oxidoreductase |
| M. marinum M | MMAR_0260 | - | 1e-138 | 76.82% (289) | oxidoreductase |
| M. avium 104 | MAV_0235 | - | 1e-16 | 25.17% (302) | taurine catabolism dioxygenase TauD/TfdA |
| M. smegmatis MC2 155 | MSMEG_0181 | - | 7e-13 | 24.91% (269) | alpha-ketoglutarate-dependent taurine dioxygenase |
| M. thermoresistible (build 8) | TH_0024 | - | 4e-07 | 24.18% (273) | dioxygenase, TauD/TfdA family protein |
| M. ulcerans Agy99 | MUL_4854 | - | 1e-136 | 75.78% (289) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_4182 | - | 3e-12 | 25.17% (290) | taurine catabolism dioxygenase TauD/TfdA |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0100|M.bovis_AF2122/97 ------------------------------------------MTLKVKGE
Rv0097|M.tuberculosis_H37Rv ------------------------------------------MTLKVKGE
MMAR_0260|M.marinum_M ------------------------------------------MTLNVKGE
MUL_4854|M.ulcerans_Agy99 ------------------------------------------MTLNVKGE
MAB_0659|M.abscessus_ATCC_1997 ------------------------------------------MTLNVKGE
MLBr_01992|M.leprae_Br4923 ------------------------------------------MTLDVKGD
TH_0024|M.thermoresistible__bu ---------------------------------------MSRLTINRLTA
Mvan_4182|M.vanbaalenii_PYR-1 ---------------------------------------MTLLTINKLTS
MAV_0235|M.avium_104 ------------------------------------------MEIVASGP
MSMEG_0181|M.smegmatis_MC2_155 MTDTRHAPPPAPRPIPEYDVSAGPFSHLAAERDRLAALRWRHFDAEQVGT
Mflv_3107|M.gilvum_PYR-GCK ---------------------------------------MSSPDVVKLGA
Mb0100|M.bovis_AF2122/97 GLGAQVTGVDPK--NLDDITTDEIRDIVYTNKLVVLKDVH-PSPREFIKL
Rv0097|M.tuberculosis_H37Rv GLGAQVTGVDPK--NLDDITTDEIRDIVYTNKLVVLKDVH-PSPREFIKL
MMAR_0260|M.marinum_M GLGAQITGVDPK--NLDDITTDEIRDIVYANKLVILKDVN-PSPEEFLKL
MUL_4854|M.ulcerans_Agy99 GLGAQITGVDPK--ILDDITTDEIRDIVYANKLVILKDVN-PSPEEFLKL
MAB_0659|M.abscessus_ATCC_1997 GLGAQVTGIDPG--NLDGITTEEIRELVYRHKLVVLKGVH-PTPEQFIEL
MLBr_01992|M.leprae_Br4923 GLGAQVTGVDPK--NLDSISTAEIRKIVYVNKLVVLKDVH-PTPEEFIKL
TH_0024|M.thermoresistible__bu SVGAEVTGTTADELAADAALGAAVLDALEEHGVLVFRGLR-IDPQTQVKF
Mvan_4182|M.vanbaalenii_PYR-1 SVGAEVTGLDPGRLAGDDALGTAVLDALEDNGVLVFPGLH-LEPEVQVEF
MAV_0235|M.avium_104 GFAAELRGVTIADVAASPDVYAQVRAAFEEHSVLVFRDQH-VSDEAQLAF
MSMEG_0181|M.smegmatis_MC2_155 TLGAQISGVDLTR-PLAGAVFDELRTALHEYKVLFFRDQP-MSADAHAAL
Mflv_3107|M.gilvum_PYR-GCK AIGARIDGVDLAR-GIDAGTAAQINAALLEHKVIFFRGQHDLDDDGQLEF
..*.: * : . ::.: . :
Mb0100|M.bovis_AF2122/97 GRIIGQIVPYYEPMYHHEDHPEIFVSSTEEGQGVPKTG---------AFW
Rv0097|M.tuberculosis_H37Rv GRIIGQIVPYYEPMYHHEDHPEIFVSSTEEGQGVPKTG---------AFW
MMAR_0260|M.marinum_M GKIVGQIVPYYEPMYHHEDHPEIFVSSTEEGQGVPKTG---------AFW
MUL_4854|M.ulcerans_Agy99 GKIVGQIVPYYEPMYHHEDHPEIFVSSTVEGQGVPKTG---------AFW
MAB_0659|M.abscessus_ATCC_1997 GRLIGEIVPYYEPVYHHQDHPEIFVSSTEEGQGVPRTG---------AFW
MLBr_01992|M.leprae_Br4923 GRIIGEIVPYYEPIYRHKDYPEIFVSSTEEGQGVPNTG---------AFW
TH_0024|M.thermoresistible__bu CRHLGEVDHSSDG--HHPVAGIYPVTLDKSKNSSAAYLRATFDWHIDGCT
Mvan_4182|M.vanbaalenii_PYR-1 CRRLGEIDFSSDG--HHRVAGIYPVTLDKSKNSSAAYLRATFDWHIDGCT
MAV_0235|M.avium_104 SRRFGPLGVTKVGAVGHGSHLVVLKTLDDDGNVVPADHRLALENKANQLW
MSMEG_0181|M.smegmatis_MC2_155 ARQFGPLEV--HPLLPANSAESALARFQKDANVSGYEN----------AW
Mflv_3107|M.gilvum_PYR-GCK ARALGTPTTAHPTVTSRGAKVLPIDSRYDKADS----------------W
: .* . :
Mb0100|M.bovis_AF2122/97 HIDYMFMPEPFAFSMVLPLAVPGHDRGTYFIDLARVWQSLPAAKRDPARG
Rv0097|M.tuberculosis_H37Rv HIDYMFMPEPFAFSMVLPLAVPGHDRGTYFIDLARVWQSLPAAKRDPARG
MMAR_0260|M.marinum_M HIDYMFMPEPFAFSMVLPLAVPGHDRGTYFIDLAKVWQSLPAAQQAPARG
MUL_4854|M.ulcerans_Agy99 HIDYMFMPEPFAFSMVLPLAVPGHDRGTYFIDLAKVWQSLPSAQQAPARG
MAB_0659|M.abscessus_ATCC_1997 HVDYMFMPKPFAFSMVLPLAVPGHDRGTYFIDLSKVWESLPAKTKDAALG
MLBr_01992|M.leprae_Br4923 HVDYIFMPEPFAFSMTLPLAMPGHDRGTHFIDLSQVWESLPNAMKDSVRG
TH_0024|M.thermoresistible__bu PTG---DEYPQKATVLSAVQVADRGGETEFASSYGAYEALSEEEKRHVET
Mvan_4182|M.vanbaalenii_PYR-1 PTG---DDYPQMATVLSAKQVAESGGETEFASSYAAYDALTDAEKQRFAS
MAV_0235|M.avium_104 HTDSSFKRVPALASVLSSRIVPGRGGETEYVSTRIAFERLDPGLRERVEN
MSMEG_0181|M.smegmatis_MC2_155 HHDVTWRPEPSILAILHAIEVPPIGGDTLFADMYAAYDSLDDETKAEIDR
Mflv_3107|M.gilvum_PYR-GCK HTDVTFVDRIPKASLLRAVTLPAYGGTTAWASTEAAYDRLPAPLRALTEN
. :: . :. . * : . .:: * :
Mb0100|M.bovis_AF2122/97 TVSTHD----PRRHIKIRPSDVYRPIGEVWDEINRTTPPIKWPTVIRHPK
Rv0097|M.tuberculosis_H37Rv TVSTHD----PRRHIKIRPSDVYRPIGEVWDEINRTTPPIKWPTVIRHPK
MMAR_0260|M.marinum_M TLSTHD----PRRHIKIRPSDVYRPIGEVWDEISRATPPIKWPTVIRHPK
MUL_4854|M.ulcerans_Agy99 TLSTHD----PRRHIKIRPSDVYRPIGEVWDEISRATPPIKWPTVIRHPK
MAB_0659|M.abscessus_ATCC_1997 TFSTHT----PRRYIKIRPSDVYRPIGEILAEIERTTPPQKWPTVIKHPK
MLBr_01992|M.leprae_Br4923 TYSNHS----PRRYIKIRPSDVYRPVGEVLAEIEEVTPPQKWPTVIKHPK
TH_0024|M.thermoresistible__bu LRVVHS----LEASQRRVTPDPTPEQLARW----RARPTHEHPLVWTHRN
Mvan_4182|M.vanbaalenii_PYR-1 LRVVHS----LEASQRRVNPDPSPEELARW----RARPTHEHPLVWTHRT
MAV_0235|M.avium_104 SFAWHE----YAYSRGKIAPDLARPEER------AALPPQCWRLVWRNPV
MSMEG_0181|M.smegmatis_MC2_155 LDAAHD----FTYYLRGLVPDEKIAELQ------AAHPPVTHPVVCTHPI
Mflv_3107|M.gilvum_PYR-GCK LWAVHTNTYDYAADADARLVPLADTERQYREEFVSDYYETEHPVVRVHPE
* * :
Mb0100|M.bovis_AF2122/97 TGQEILYICATGTTKIEDKDGNPVDPEVLQELMAATGQLDPEYQSPFIHT
Rv0097|M.tuberculosis_H37Rv TGQEILYICATGTTKIEDKDGNPVDPEVLQELMAATGQLDPEYQSPFIHT
MMAR_0260|M.marinum_M TGEEILYICATGTTKIEDKDGNLVDPAVLAELLAATGQLDPEYNSPFIHT
MUL_4854|M.ulcerans_Agy99 TGEEILYICATGTTKIEDKDGNLVDPAVLAELLAATGQLDPEYNSPFIHT
MAB_0659|M.abscessus_ATCC_1997 TGEEILYICEAGTETIEDGAGRIQDAALLQQLLEASGQLDPDYASPFIHA
MLBr_01992|M.leprae_Br4923 TGQEILYICEAATVSVEDKNGNLLDPMVLQELLTASGQLDPDCKSLLIHT
TH_0024|M.thermoresistible__bu -GRKSLVLGASADYVVG------MDLDEGRALLADL--LDRATTEDRVYR
Mvan_4182|M.vanbaalenii_PYR-1 -GRKSLVLGASADYIVG------MDPEEGRALLSEL--LDRATTADKVYS
MAV_0235|M.avium_104 NGRKALYLASHAYGIEG------MEPAAARELLAAL--TEAATAPGASYL
MSMEG_0181|M.smegmatis_MC2_155 TGRRHLYVNRMFVSHIAG-----YPHDTGRALLDRL--CRTADAPEHQVR
Mflv_3107|M.gilvum_PYR-GCK TGRKVLLLGHFVKHFVG------LGQAESTALLQLL--QNRVTKLENTIR
*.. * : *:
Mb0100|M.bovis_AF2122/97 QHYQVGDIILWDNRVLMHRAKHGSAAGTLTTYRLTMLDGLKTPGYAA---
Rv0097|M.tuberculosis_H37Rv QHYQVGDIILWDNRVLMHRAKHGSAAGTLTTYRLTMLDGLKTPGYAA---
MMAR_0260|M.marinum_M QHYEVGDIILWDNRVLMHRAKHGTASGTLTTYRLTMLDGLETPGYPA---
MUL_4854|M.ulcerans_Agy99 QHYEVGDIILWDNRVLMHRAKHGTASGTLTTYRLTMLDGLETPGYPA---
MAB_0659|M.abscessus_ATCC_1997 QHYEVGDIVLWDNRSLVHRAKHGTASGTLTTYRLTMLDGLEAPGFAA---
MLBr_01992|M.leprae_Br4923 QHYEVGDVVLWDNRALVHRAKHGTVSGTLITYRLTLLDGLKTPGYAV---
TH_0024|M.thermoresistible__bu HRWSVGDTVIWDNRGVLHRAAPYPEDSPREMLRTTVLGDEPIQ-------
Mvan_4182|M.vanbaalenii_PYR-1 HHWAVGDTVIWDNRGVLHRAARYDENSPREMLRTTVLGDEPIQ-------
MAV_0235|M.avium_104 HSWRAGDVVMWDNRATMHRGRPWPAHQPRCMVRSTIAATAADGLEAMYPP
MSMEG_0181|M.smegmatis_MC2_155 FRWAPDSVAIWDNRAVQHYAASGYWPHTRIMERASVTGPVPCR-------
Mflv_3107|M.gilvum_PYR-GCK WSWELGDIAVWDNRATQHYAVSDYDDQFRRLSRVTLAGDIPVDVYGRRSR
: .. :**** * . * ::
Mb0100|M.bovis_AF2122/97 -----------------------
Rv0097|M.tuberculosis_H37Rv -----------------------
MMAR_0260|M.marinum_M -----------------------
MUL_4854|M.ulcerans_Agy99 -----------------------
MAB_0659|M.abscessus_ATCC_1997 -----------------------
MLBr_01992|M.leprae_Br4923 -----------------------
TH_0024|M.thermoresistible__bu -----------------------
Mvan_4182|M.vanbaalenii_PYR-1 -----------------------
MAV_0235|M.avium_104 WHAVAR-----------------
MSMEG_0181|M.smegmatis_MC2_155 -----------------------
Mflv_3107|M.gilvum_PYR-GCK VIAGDASTYSQVVVPLKLAGLAS