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MSLLTINKLTPSVGAEVLGVDPVRLASDESLAAAVLDALEDNGVLVFPDLHLAPEAQVAFSRRLGAVDHS ADGHHPVAGIYPVTLDKSKNASAAYLRATFDWHIDGCTPIGDECPQRATVLSAVQVADRGGETEFANSYA AYEAFSDEEKERYAALRVVHSLEASQSRVNPDPSPEELARWRSRPTHEHPLVWTHRSGRKSLVLGASAHY VVGMDYDEGRALLAELLDRATQPELVYSHSWSVGDTVIWDNNGVLHRAAPYDPDSQREMLRTTVLGDEPI Q
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2472 | - | - | 100% (281) | taurine catabolism dioxygenase TauD/TfdA |
| M. gilvum PYR-GCK | Mflv_3107 | - | 2e-21 | 30.27% (294) | taurine dioxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3440 | - | 2e-20 | 31.12% (286) | dioxygenase |
| M. tuberculosis H37Rv | Rv3406 | - | 2e-20 | 31.12% (286) | dioxygenase |
| M. leprae Br4923 | MLBr_01992 | - | 4e-09 | 24.91% (273) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_3621c | - | 3e-21 | 27.70% (296) | taurine dioxygenase |
| M. marinum M | MMAR_1141 | tauD | 4e-19 | 30.03% (293) | taurine catabolism dioxygenase, TauD |
| M. avium 104 | MAV_3959 | - | 1e-134 | 81.85% (281) | taurine catabolism dioxygenase TauD, TfdA family protein |
| M. smegmatis MC2 155 | MSMEG_0291 | - | 1e-126 | 76.16% (281) | dioxygenase, TauD/TfdA family protein |
| M. thermoresistible (build 8) | TH_0024 | - | 1e-127 | 79.00% (281) | dioxygenase, TauD/TfdA family protein |
| M. ulcerans Agy99 | MUL_0904 | tauD | 3e-19 | 30.03% (293) | taurine catabolism dioxygenase, TauD |
| M. vanbaalenii PYR-1 | Mvan_4182 | - | 1e-131 | 80.43% (281) | taurine catabolism dioxygenase TauD/TfdA |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3440|M.bovis_AF2122/97 -----MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVV
Rv3406|M.tuberculosis_H37Rv -----MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVV
MMAR_1141|M.marinum_M -----MTDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVI
MUL_0904|M.ulcerans_Agy99 -----MTDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVI
Mflv_2472|M.gilvum_PYR-GCK ------MSLLTINKLTPSVGAEVLGVDPVRLASDESLAAAVLDALEDNGV
MAV_3959|M.avium_104 ------MSLLTITKLTDSVGAEVTGLDPAALAHDDSVGEAVLDALEDNGV
Mvan_4182|M.vanbaalenii_PYR-1 ------MTLLTINKLTSSVGAEVTGLDPGRLAGDDALGTAVLDALEDNGV
TH_0024|M.thermoresistible__bu ------MSRLTINRLTASVGAEVTGTTADELAADAALGAAVLDALEEHGV
MSMEG_0291|M.smegmatis_MC2_155 ------MSVLTINKLTASVGAEVVGIDSERLATDDGIAAAVLDALEDNGV
MAB_3621c|M.abscessus_ATCC_199 MNGVAPLSKIRVQPLTCTIGAELFDVDLAEASRSDELFGEIRTLLLEHKV
MLBr_01992|M.leprae_Br4923 ---------MTLDVKGDGLGAQVTGVDPKNLDSIS--TAEIRKIVYVNKL
: : :**:: . : : :
Mb3440|M.bovis_AF2122/97 FFRGQHQLDDAEQLAFAGLLGTPIGHPAAIALADDAPIITPINSEFGKAN
Rv3406|M.tuberculosis_H37Rv FFRGQHQLDDAEQLAFAGLLGTPIGHPAAIALADDAPIITPINSEFGKAN
MMAR_1141|M.marinum_M FFRNQHHLDDQQQLQFAGLLGTPIGHPAAAAALPDAPIITPINSEWGKAN
MUL_0904|M.ulcerans_Agy99 FFRNQHHLDDQQQLQFAGLLGTPIGHPAAAAALPDAPIITPINSEWGKAN
Mflv_2472|M.gilvum_PYR-GCK LVFPDLHLAPEAQVAFSRRLGAVDHSADGHHPVAGIYPVTLDKSKNASAA
MAV_3959|M.avium_104 LVFRGLYLDPAAQVAFCGRLGEVDHSSDGHHPVPGIYPITLDKSKNASAA
Mvan_4182|M.vanbaalenii_PYR-1 LVFPGLHLEPEVQVEFCRRLGEIDFSSDGHHRVAGIYPVTLDKSKNSSAA
TH_0024|M.thermoresistible__bu LVFRGLRIDPQTQVKFCRHLGEVDHSSDGHHPVAGIYPVTLDKSKNSSAA
MSMEG_0291|M.smegmatis_MC2_155 LVFRGLYLEPEAQVAFSQRLGEVDRSADGHHPVSGIYPITLDQTKNKAAE
MAB_3621c|M.abscessus_ATCC_199 LFLRDQNITRGEHVALARRFGPLEDHPVAGSDPDHPGLVRIYKEIDSAPE
MLBr_01992|M.leprae_Br4923 VVLKDVHPTPEEFIKLGRIIGEIVPYYEPIYRHKDYPEIFVSSTEEG-QG
.. : : :* : .
Mb3440|M.bovis_AF2122/97 RWHTDVTFAAN---------YPAASVLRAVSLPSYGGSTLWANTAAAYAE
Rv3406|M.tuberculosis_H37Rv RWHTDVTFAAN---------YPAASVLRAVSLPSYGGSTLWANTAAAYAE
MMAR_1141|M.marinum_M RWHTDVTFAAN---------YPAASILRAVTLPNYGGSTLWANTATAYAE
MUL_0904|M.ulcerans_Agy99 RWHTDVTFAAN---------YPAASILRAVTLPNYGGSTLWANTATAYAE
Mflv_2472|M.gilvum_PYR-GCK YLRATFDWHIDGCTPIGDECPQRATVLSAVQVADRGGETEFANSYAAYEA
MAV_3959|M.avium_104 YLKATFDWHIDGCTPLGDECPQKATVLSAVRVAERGGETEFANSYGAYDA
Mvan_4182|M.vanbaalenii_PYR-1 YLRATFDWHIDGCTPTGDDYPQMATVLSAKQVAESGGETEFASSYAAYDA
TH_0024|M.thermoresistible__bu YLRATFDWHIDGCTPTGDEYPQKATVLSAVQVADRGGETEFASSYGAYEA
MSMEG_0291|M.smegmatis_MC2_155 YLKATFDWHIDGCTPLNDECPQKATVLSAIEVAARGGETEFANAYAAYES
MAB_3621c|M.abscessus_ATCC_199 HYENSYHCDATWR-----ESPPMGAVLRCVETPPVGGDTIWVNMVEAYRR
MLBr_01992|M.leprae_Br4923 VPNTGAFWHVDYIFMP---EPFAFSMTLPLAMPGHDRGTHFIDLSQVWES
. :: . . * : . .:
Mb3440|M.bovis_AF2122/97 LPEPLKCLTENLWALHTNRYDYVT---TKPLTAAQRAFRQVFEKPDFRTE
Rv3406|M.tuberculosis_H37Rv LPEPLKCLTENLWALHTNRYDYVT---TKPLTAAQRAFRQVFEKPDFRTE
MMAR_1141|M.marinum_M LPEPLKCLVENLWALHTNRYDYVANEAVQALTDTQQAFRQAFQKPDFRTE
MUL_0904|M.ulcerans_Agy99 LPEPLKCLVENLWALHTNRYDYVANEAVQALTDTQQAFRQAFQKPDFRTE
Mflv_2472|M.gilvum_PYR-GCK FSDEEKERYAALRVVHSLEASQSR------VNPDPSPEELARWRSRPTHE
MAV_3959|M.avium_104 LTDDEKQRFGALRVVHSLEASQRR------VYPDPSPELVARWRSRRTHE
Mvan_4182|M.vanbaalenii_PYR-1 LTDAEKQRFASLRVVHSLEASQRR------VNPDPSPEELARWRARPTHE
TH_0024|M.thermoresistible__bu LSEEEKRHVETLRVVHSLEASQRR------VTPDPTPEQLARWRARPTHE
MSMEG_0291|M.smegmatis_MC2_155 LDADEKQRYARLRVVHSLEASQRR------VYPDPTAEQRRRWAARPTHE
MAB_3621c|M.abscessus_ATCC_199 LPAAVRDRIRDLRARHSIEASFGA--------AMSMRQRHELHERYPDAE
MLBr_01992|M.leprae_Br4923 LPNAMKDSVRGTYSNHSPRRYIKIR--PSDVYRPVGEVLAEIEEVTPPQK
: : *: . :
Mb3440|M.bovis_AF2122/97 HPVVRVHPETGERTLLAGDFVRSFVGLDSHE-----------SRVLFEVL
Rv3406|M.tuberculosis_H37Rv HPVVRVHPETGERTLLAGDFVRSFVGLDSHE-----------SRVLFEVL
MMAR_1141|M.marinum_M HPVVRVHPETGERTLLAGDFVRGFVGLDSQE-----------SSALFELL
MUL_0904|M.ulcerans_Agy99 HPVVRVHPETGERTLLAGDFVRGFVGLDSQE-----------SSALFELL
Mflv_2472|M.gilvum_PYR-GCK HPLVWTH-RSGRKSLVLGASAHYVVGMDYDE-----------GRALLAEL
MAV_3959|M.avium_104 HPLVWTH-RSGRKSLVLGASADYVVGMDVDE-----------GRALLEEL
Mvan_4182|M.vanbaalenii_PYR-1 HPLVWTH-RTGRKSLVLGASADYIVGMDPEE-----------GRALLSEL
TH_0024|M.thermoresistible__bu HPLVWTH-RNGRKSLVLGASADYVVGMDLDE-----------GRALLADL
MSMEG_0291|M.smegmatis_MC2_155 NPLVWTH-RNGRKSLVLGASADHIVGMDRDE-----------GRALLDGL
MAB_3621c|M.abscessus_ATCC_199 HPVVRTHPETGEEILFVNSFTTHLVNYHRPENVRFGIDYAPGASELLQYL
MLBr_01992|M.leprae_Br4923 WPTVIKHPKTGQEILYICEAATVSVEDKNGN---------LLDPMVLQEL
* * * ..*.. * . * . : :: *
Mb3440|M.bovis_AF2122/97 QRRITMPE------NTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMH
Rv3406|M.tuberculosis_H37Rv QRRITMPE------NTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMH
MMAR_1141|M.marinum_M QRRITSPE------NTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLH
MUL_0904|M.ulcerans_Agy99 QRRITSPE------NTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLH
Mflv_2472|M.gilvum_PYR-GCK LDRATQPE------LVYSHSWSVGDTVIWDNNGVLHRAAPYDPDSQREML
MAV_3959|M.avium_104 LQRATVPE------RVYRHGWSIGDTVIWDNRGVLHRAAPYDPDSSREML
Mvan_4182|M.vanbaalenii_PYR-1 LDRATTAD------KVYSHHWAVGDTVIWDNRGVLHRAARYDENSPREML
TH_0024|M.thermoresistible__bu LDRATTED------RVYRHRWSVGDTVIWDNRGVLHRAAPYPEDSPREML
MSMEG_0291|M.smegmatis_MC2_155 LARTTTPD------KVYSHKWSVGDTVIWDNQGVLHRAAPYEPDSPRHML
MAB_3621c|M.abscessus_ATCC_199 MRQATVPE------FQVRWRWTPNSVAIWDNRSTQHYAVQDYWPAVRKME
MLBr_01992|M.leprae_Br4923 LTASGQLDPDCKSLLIHTQHYEVGDVVLWDNRALVHRAKHGTVSGTLITY
: : ....:***.. * *
Mb3440|M.bovis_AF2122/97 RVTLMGDVPVDVYGQASRVISGAPMEIAG
Rv3406|M.tuberculosis_H37Rv RVTLMGDVPVDVYGQASRVISGAPMEIAG
MMAR_1141|M.marinum_M RVTLMGDVPVDVHGQRSRVISGAPLALAG
MUL_0904|M.ulcerans_Agy99 RVTLMGDVPVDVHGQRSRVISGAPLALAG
Mflv_2472|M.gilvum_PYR-GCK RTTVLGDEPIQ------------------
MAV_3959|M.avium_104 RTTVLGDEPIQ------------------
Mvan_4182|M.vanbaalenii_PYR-1 RTTVLGDEPIQ------------------
TH_0024|M.thermoresistible__bu RTTVLGDEPIQ------------------
MSMEG_0291|M.smegmatis_MC2_155 RTTVLGDEPIR------------------
MAB_3621c|M.abscessus_ATCC_199 RAGICGDIPFS------------------
MLBr_01992|M.leprae_Br4923 RLTLLDGLKTPGYAV--------------
* : ..