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EIVASGPGFAAELRGVTIADVAASPDVYAQVRAAFEEHSVLVFRDQHVSDEAQLAFSRRFGPLGVTKVGA VGHGSHLVVLKTLDDDGNVVPADHRLALENKANQLWHTDSSFKRVPALASVLSSRIVPGRGGETEYVSTR IAFERLDPGLRERVENSFAWHEYAYSRGKIAPDLARPEERAALPPQCWRLVWRNPVNGRKALYLASHAYG IEGMEPAAARELLAALTEAATAPGASYLHSWRAGDVVMWDNRATMHRGRPWPAHQPRCMVRSTIAATAAD GLEAMYPPWHAVAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0235 | - | - | 100% (295) | taurine catabolism dioxygenase TauD/TfdA |
| M. avium 104 | MAV_3959 | - | 8e-26 | 32.36% (275) | taurine catabolism dioxygenase TauD, TfdA family protein |
| M. avium 104 | MAV_4353 | - | 4e-25 | 33.73% (252) | alpha-ketoglutarate-dependent taurine dioxygenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3440 | - | 2e-21 | 29.29% (280) | dioxygenase |
| M. gilvum PYR-GCK | Mflv_2472 | - | 1e-33 | 36.00% (275) | taurine catabolism dioxygenase TauD/TfdA |
| M. tuberculosis H37Rv | Rv3406 | - | 2e-21 | 29.29% (280) | dioxygenase |
| M. leprae Br4923 | MLBr_01992 | - | 1e-15 | 24.35% (308) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0086 | - | 1e-21 | 30.20% (298) | putative taurine dioxygenase |
| M. marinum M | MMAR_1141 | tauD | 4e-22 | 29.75% (279) | taurine catabolism dioxygenase, TauD |
| M. smegmatis MC2 155 | MSMEG_0291 | - | 3e-32 | 34.94% (269) | dioxygenase, TauD/TfdA family protein |
| M. thermoresistible (build 8) | TH_0024 | - | 2e-33 | 35.93% (270) | dioxygenase, TauD/TfdA family protein |
| M. ulcerans Agy99 | MUL_0904 | tauD | 3e-22 | 29.75% (279) | taurine catabolism dioxygenase, TauD |
| M. vanbaalenii PYR-1 | Mvan_4182 | - | 6e-30 | 33.33% (270) | taurine catabolism dioxygenase TauD/TfdA |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3440|M.bovis_AF2122/97 MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQ
Rv3406|M.tuberculosis_H37Rv MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQ
MMAR_1141|M.marinum_M MTDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVIFFRNQ
MUL_0904|M.ulcerans_Agy99 MTDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVIFFRNQ
MAB_0086|M.abscessus_ATCC_1997 MSSDLRVVKLGENIGARIDGVRLG-EVDTATASAINEAMLEHKVVFFRGQ
Mflv_2472|M.gilvum_PYR-GCK -MSLLTINKLTPSVGAEVLGVDPVRLASDESLAAAVLDALEDNGVLVFPD
Mvan_4182|M.vanbaalenii_PYR-1 -MTLLTINKLTSSVGAEVTGLDPGRLAGDDALGTAVLDALEDNGVLVFPG
TH_0024|M.thermoresistible__bu -MSRLTINRLTASVGAEVTGTTADELAADAALGAAVLDALEEHGVLVFRG
MSMEG_0291|M.smegmatis_MC2_155 -MSVLTINKLTASVGAEVVGIDSERLATDDGIAAAVLDALEDNGVLVFRG
MAV_0235|M.avium_104 ----MEIVASGPGFAAELRGVTIADVAASPDVYAQVRAAFEEHSVLVFRD
MLBr_01992|M.leprae_Br4923 ----MTLDVKGDGLGAQVTGVDPKNLDSIS--TAEIRKIVYVNKLVVLKD
: : ..*.: * . : :..
Mb3440|M.bovis_AF2122/97 HQLDDAEQLAFAGLLGTPIGHPAAIALADDAPIITPINSEFGKANRWHTD
Rv3406|M.tuberculosis_H37Rv HQLDDAEQLAFAGLLGTPIGHPAAIALADDAPIITPINSEFGKANRWHTD
MMAR_1141|M.marinum_M HHLDDQQQLQFAGLLGTPIGHPAAAAALPDAPIITPINSEWGKANRWHTD
MUL_0904|M.ulcerans_Agy99 HHLDDQQQLQFAGLLGTPIGHPAAAAALPDAPIITPINSEWGKANRWHTD
MAB_0086|M.abscessus_ATCC_1997 HHVDDEVQFAFAKSMGIPT-TPHPTLTSSDVKVLPIDSEEGGRANQWHTD
Mflv_2472|M.gilvum_PYR-GCK LHLAPEAQVAFSRRLG--AVDHSADGHHPVAGIYPVTLDKSKNASAAYLR
Mvan_4182|M.vanbaalenii_PYR-1 LHLEPEVQVEFCRRLG--EIDFSSDGHHRVAGIYPVTLDKSKNSSAAYLR
TH_0024|M.thermoresistible__bu LRIDPQTQVKFCRHLG--EVDHSSDGHHPVAGIYPVTLDKSKNSSAAYLR
MSMEG_0291|M.smegmatis_MC2_155 LYLEPEAQVAFSQRLG--EVDRSADGHHPVSGIYPITLDQTKNKAAEYLK
MAV_0235|M.avium_104 QHVSDEAQLAFSRRFGPLGVTKVGAVGHGSHLVVLKTLDDDGNVVPADHR
MLBr_01992|M.leprae_Br4923 VHPTPEEFIKLGRIIGEIVPYYEPIYRHKDYPEIFVSSTEEGQGVPNTGA
. : :* . .
Mb3440|M.bovis_AF2122/97 VTFAANYP--------------AASVLRAVSLPSYGGSTLWANTAAAYAE
Rv3406|M.tuberculosis_H37Rv VTFAANYP--------------AASVLRAVSLPSYGGSTLWANTAAAYAE
MMAR_1141|M.marinum_M VTFAANYP--------------AASILRAVTLPNYGGSTLWANTATAYAE
MUL_0904|M.ulcerans_Agy99 VTFAANYP--------------AASILRAVTLPNYGGSTLWANTATAYAE
MAB_0086|M.abscessus_ATCC_1997 VTFVDRIP--------------KASILRAVELPPYGGTTTWTSTVAAYRQ
Mflv_2472|M.gilvum_PYR-GCK ATFDWHIDGCTPIG---DECPQRATVLSAVQVADRGGETEFANSYAAYEA
Mvan_4182|M.vanbaalenii_PYR-1 ATFDWHIDGCTPTG---DDYPQMATVLSAKQVAESGGETEFASSYAAYDA
TH_0024|M.thermoresistible__bu ATFDWHIDGCTPTG---DEYPQKATVLSAVQVADRGGETEFASSYGAYEA
MSMEG_0291|M.smegmatis_MC2_155 ATFDWHIDGCTPLN---DECPQKATVLSAIEVAARGGETEFANAYAAYES
MAV_0235|M.avium_104 LALENKANQLWHTDSSFKRVPALASVLSSRIVPGRGGETEYVSTRIAFER
MLBr_01992|M.leprae_Br4923 FWHVDYIFMP---------EPFAFSMTLPLAMPGHDRGTHFIDLSQVWES
:: . :. . * : . .:
Mb3440|M.bovis_AF2122/97 LPEPLKCLTENLWALHTNRYDYVT---TKPLTAAQRA-----FRQVFEKP
Rv3406|M.tuberculosis_H37Rv LPEPLKCLTENLWALHTNRYDYVT---TKPLTAAQRA-----FRQVFEKP
MMAR_1141|M.marinum_M LPEPLKCLVENLWALHTNRYDYVANEAVQALTDTQQA-----FRQAFQKP
MUL_0904|M.ulcerans_Agy99 LPEPLKCLVENLWALHTNRYDYVANEAVQALTDTQQA-----FRQAFQKP
MAB_0086|M.abscessus_ATCC_1997 LPKPLQDLADNLWAMHNNQFDYTQVDPAKVAELLAKAGSGSKYVREFGAT
Mflv_2472|M.gilvum_PYR-GCK FSDEEKERYAALRVVHSLEASQSRVNPDPSPEELARW-----------RS
Mvan_4182|M.vanbaalenii_PYR-1 LTDAEKQRFASLRVVHSLEASQRRVNPDPSPEELARW-----------RA
TH_0024|M.thermoresistible__bu LSEEEKRHVETLRVVHSLEASQRRVTPDPTPEQLARW-----------RA
MSMEG_0291|M.smegmatis_MC2_155 LDADEKQRYARLRVVHSLEASQRRVYPDPTAEQRRRW-----------AA
MAV_0235|M.avium_104 LDPGLRERVENSFAWHEYAYSRGKIAPDLARPEER-------------AA
MLBr_01992|M.leprae_Br4923 LPNAMKDSVRGTYSNHSPRR-YIKIRPSDVYRPVGEV------LAEIEEV
: : *
Mb3440|M.bovis_AF2122/97 DFRTEHPVVRVHPETGERTLLAGDFVRSFVG------LDSHESRVLFEVL
Rv3406|M.tuberculosis_H37Rv DFRTEHPVVRVHPETGERTLLAGDFVRSFVG------LDSHESRVLFEVL
MMAR_1141|M.marinum_M DFRTEHPVVRVHPETGERTLLAGDFVRGFVG------LDSQESSALFELL
MUL_0904|M.ulcerans_Agy99 DFRTEHPVVRVHPETGERTLLAGDFVRGFVG------LDSQESSALFELL
MAB_0086|M.abscessus_ATCC_1997 HFETHHPVVRVHPETGEKALLLGNFVKRILD------VSASESQALFRMF
Mflv_2472|M.gilvum_PYR-GCK RPTHEHPLVWTHRS-GRKSLVLGASAHYVVG------MDYDEGRALLAEL
Mvan_4182|M.vanbaalenii_PYR-1 RPTHEHPLVWTHRT-GRKSLVLGASADYIVG------MDPEEGRALLSEL
TH_0024|M.thermoresistible__bu RPTHEHPLVWTHRN-GRKSLVLGASADYVVG------MDLDEGRALLADL
MSMEG_0291|M.smegmatis_MC2_155 RPTHENPLVWTHRN-GRKSLVLGASADHIVG------MDRDEGRALLDGL
MAV_0235|M.avium_104 LPPQCWRLVWRNPVNGRKALYLASHAYGIEG------MEPAAARELLAAL
MLBr_01992|M.leprae_Br4923 TPPQKWPTVIKHPKTGQEILYICEAATVSVEDKNGNLLDPMVLQELLTAS
* : *.. * . :. *:
Mb3440|M.bovis_AF2122/97 --QRRITMPENTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTL
Rv3406|M.tuberculosis_H37Rv --QRRITMPENTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTL
MMAR_1141|M.marinum_M --QRRITSPENTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRVTL
MUL_0904|M.ulcerans_Agy99 --QRRITSPENTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRVTL
MAB_0086|M.abscessus_ATCC_1997 --QDRVTWLENTIRWSWELGDVAMWDNRATQHYAISDYGDQPRRMHRVTL
Mflv_2472|M.gilvum_PYR-GCK --LDRATQPELVYSHSWSVGDTVIWDNNGVLHRAAPYDPDSQREMLRTTV
Mvan_4182|M.vanbaalenii_PYR-1 --LDRATTADKVYSHHWAVGDTVIWDNRGVLHRAARYDENSPREMLRTTV
TH_0024|M.thermoresistible__bu --LDRATTEDRVYRHRWSVGDTVIWDNRGVLHRAAPYPEDSPREMLRTTV
MSMEG_0291|M.smegmatis_MC2_155 --LARTTTPDKVYSHKWSVGDTVIWDNQGVLHRAAPYEPDSPRHMLRTTV
MAV_0235|M.avium_104 --TEAATAPGASYLHSWRAGDVVMWDNRATMHRGRPWPAHQPRCMVRSTI
MLBr_01992|M.leprae_Br4923 GQLDPDCKSLLIHTQHYEVGDVVLWDNRALVHRAKHGTVSGTLITYRLTL
: **..:***.. * . * *:
Mb3440|M.bovis_AF2122/97 MGDVPVDVYGQASRVISG---------APMEIAG
Rv3406|M.tuberculosis_H37Rv MGDVPVDVYGQASRVISG---------APMEIAG
MMAR_1141|M.marinum_M MGDVPVDVHGQRSRVISG---------APLALAG
MUL_0904|M.ulcerans_Agy99 MGDVPVDVHGQRSRVISG---------APLALAG
MAB_0086|M.abscessus_ATCC_1997 AGDVPVGVNGESSRVIAGDASDYSVIDNPKRLVA
Mflv_2472|M.gilvum_PYR-GCK LGDEPIQ---------------------------
Mvan_4182|M.vanbaalenii_PYR-1 LGDEPIQ---------------------------
TH_0024|M.thermoresistible__bu LGDEPIQ---------------------------
MSMEG_0291|M.smegmatis_MC2_155 LGDEPIR---------------------------
MAV_0235|M.avium_104 AATAADGLEAMYPPWHAVAR--------------
MLBr_01992|M.leprae_Br4923 LDGLKTPGYAV-----------------------