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TLLTINKLTSSVGAEVTGLDPGRLAGDDALGTAVLDALEDNGVLVFPGLHLEPEVQVEFCRRLGEIDFSS DGHHRVAGIYPVTLDKSKNSSAAYLRATFDWHIDGCTPTGDDYPQMATVLSAKQVAESGGETEFASSYAA YDALTDAEKQRFASLRVVHSLEASQRRVNPDPSPEELARWRARPTHEHPLVWTHRTGRKSLVLGASADYI VGMDPEEGRALLSELLDRATTADKVYSHHWAVGDTVIWDNRGVLHRAARYDENSPREMLRTTVLGDEPIQ *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4182 | - | - | 100% (281) | taurine catabolism dioxygenase TauD/TfdA |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3440 | - | 3e-21 | 30.14% (292) | dioxygenase |
| M. gilvum PYR-GCK | Mflv_2472 | - | 1e-131 | 80.43% (281) | taurine catabolism dioxygenase TauD/TfdA |
| M. tuberculosis H37Rv | Rv3406 | - | 3e-21 | 30.14% (292) | dioxygenase |
| M. leprae Br4923 | MLBr_01992 | - | 8e-12 | 26.45% (276) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0086 | - | 3e-22 | 28.28% (290) | putative taurine dioxygenase |
| M. marinum M | MMAR_1141 | tauD | 1e-19 | 28.97% (290) | taurine catabolism dioxygenase, TauD |
| M. avium 104 | MAV_3959 | - | 1e-130 | 79.36% (281) | taurine catabolism dioxygenase TauD, TfdA family protein |
| M. smegmatis MC2 155 | MSMEG_0291 | - | 1e-120 | 73.67% (281) | dioxygenase, TauD/TfdA family protein |
| M. thermoresistible (build 8) | TH_0024 | - | 1e-132 | 79.72% (281) | dioxygenase, TauD/TfdA family protein |
| M. ulcerans Agy99 | MUL_0904 | tauD | 7e-20 | 28.97% (290) | taurine catabolism dioxygenase, TauD |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3440|M.bovis_AF2122/97 MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQ
Rv3406|M.tuberculosis_H37Rv MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQ
MMAR_1141|M.marinum_M MTDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVIFFRNQ
MUL_0904|M.ulcerans_Agy99 MTDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVIFFRNQ
MAB_0086|M.abscessus_ATCC_1997 MSSDLRVVKLGENIGARIDGVRLG-EVDTATASAINEAMLEHKVVFFRGQ
Mflv_2472|M.gilvum_PYR-GCK -MSLLTINKLTPSVGAEVLGVDPVRLASDESLAAAVLDALEDNGVLVFPD
MAV_3959|M.avium_104 -MSLLTITKLTDSVGAEVTGLDPAALAHDDSVGEAVLDALEDNGVLVFRG
Mvan_4182|M.vanbaalenii_PYR-1 -MTLLTINKLTSSVGAEVTGLDPGRLAGDDALGTAVLDALEDNGVLVFPG
TH_0024|M.thermoresistible__bu -MSRLTINRLTASVGAEVTGTTADELAADAALGAAVLDALEEHGVLVFRG
MSMEG_0291|M.smegmatis_MC2_155 -MSVLTINKLTASVGAEVVGIDSERLATDDGIAAAVLDALEDNGVLVFRG
MLBr_01992|M.leprae_Br4923 ----MTLDVKGDGLGAQVTGVDPKNLDSISTAEIRKIVYVN--KLVVLKD
: : :**.: * : :..
Mb3440|M.bovis_AF2122/97 HQLDDAEQLAFAGLLGTPIGHPAAIALADDAPIITPINSEFGK-----AN
Rv3406|M.tuberculosis_H37Rv HQLDDAEQLAFAGLLGTPIGHPAAIALADDAPIITPINSEFGK-----AN
MMAR_1141|M.marinum_M HHLDDQQQLQFAGLLGTPIGHPAAAAALPDAPIITPINSEWGK-----AN
MUL_0904|M.ulcerans_Agy99 HHLDDQQQLQFAGLLGTPIGHPAAAAALPDAPIITPINSEWGK-----AN
MAB_0086|M.abscessus_ATCC_1997 HHVDDEVQFAFAKSMGIPT-TPHPTLTSSDVKVLPIDSEEGGR-----AN
Mflv_2472|M.gilvum_PYR-GCK LHLAPEAQVAFSRRLGAVDHSADGHHPVAGIYPVTLDKSKNAS-----AA
MAV_3959|M.avium_104 LYLDPAAQVAFCGRLGEVDHSSDGHHPVPGIYPITLDKSKNAS-----AA
Mvan_4182|M.vanbaalenii_PYR-1 LHLEPEVQVEFCRRLGEIDFSSDGHHRVAGIYPVTLDKSKNSS-----AA
TH_0024|M.thermoresistible__bu LRIDPQTQVKFCRHLGEVDHSSDGHHPVAGIYPVTLDKSKNSS-----AA
MSMEG_0291|M.smegmatis_MC2_155 LYLEPEAQVAFSQRLGEVDRSADGHHPVSGIYPITLDQTKNKA-----AE
MLBr_01992|M.leprae_Br4923 VHPTPEEFIKLGRIIGEIVPYYEPIYRHKDYPEIFVSSTEEGQGVPNTGA
. : :* . : . : .
Mb3440|M.bovis_AF2122/97 RWHTDVTFAAN---------YPAASVLRAVSLPSYGGSTLWANTAAAYAE
Rv3406|M.tuberculosis_H37Rv RWHTDVTFAAN---------YPAASVLRAVSLPSYGGSTLWANTAAAYAE
MMAR_1141|M.marinum_M RWHTDVTFAAN---------YPAASILRAVTLPNYGGSTLWANTATAYAE
MUL_0904|M.ulcerans_Agy99 RWHTDVTFAAN---------YPAASILRAVTLPNYGGSTLWANTATAYAE
MAB_0086|M.abscessus_ATCC_1997 QWHTDVTFVDR---------IPKASILRAVELPPYGGTTTWTSTVAAYRQ
Mflv_2472|M.gilvum_PYR-GCK YLRATFDWHIDGCTPIGDECPQRATVLSAVQVADRGGETEFANSYAAYEA
MAV_3959|M.avium_104 YLKATFDWHIDGCTPLGDECPQKATVLSAVRVAERGGETEFANSYGAYDA
Mvan_4182|M.vanbaalenii_PYR-1 YLRATFDWHIDGCTPTGDDYPQMATVLSAKQVAESGGETEFASSYAAYDA
TH_0024|M.thermoresistible__bu YLRATFDWHIDGCTPTGDEYPQKATVLSAVQVADRGGETEFASSYGAYEA
MSMEG_0291|M.smegmatis_MC2_155 YLKATFDWHIDGCTPLNDECPQKATVLSAIEVAARGGETEFANAYAAYES
MLBr_01992|M.leprae_Br4923 FWHVDYIFMPE---------PFAFSMTLPLAMPGHDRGTHFIDLSQVWES
:. : :: . :. . * : . .:
Mb3440|M.bovis_AF2122/97 LPEPLKCLTENLWALHTNRYDYVT---TKPLTAAQRA-----FRQVFEKP
Rv3406|M.tuberculosis_H37Rv LPEPLKCLTENLWALHTNRYDYVT---TKPLTAAQRA-----FRQVFEKP
MMAR_1141|M.marinum_M LPEPLKCLVENLWALHTNRYDYVANEAVQALTDTQQA-----FRQAFQKP
MUL_0904|M.ulcerans_Agy99 LPEPLKCLVENLWALHTNRYDYVANEAVQALTDTQQA-----FRQAFQKP
MAB_0086|M.abscessus_ATCC_1997 LPKPLQDLADNLWAMHNNQFDYTQVDPAKVAELLAKAGSGSKYVREFGAT
Mflv_2472|M.gilvum_PYR-GCK FSDEEKERYAALRVVHSLEASQSRVNPDPSPEELARWR-----------S
MAV_3959|M.avium_104 LTDDEKQRFGALRVVHSLEASQRRVYPDPSPELVARWR-----------S
Mvan_4182|M.vanbaalenii_PYR-1 LTDAEKQRFASLRVVHSLEASQRRVNPDPSPEELARWR-----------A
TH_0024|M.thermoresistible__bu LSEEEKRHVETLRVVHSLEASQRRVTPDPTPEQLARWR-----------A
MSMEG_0291|M.smegmatis_MC2_155 LDADEKQRYARLRVVHSLEASQRRVYPDPTAEQRRRWA-----------A
MLBr_01992|M.leprae_Br4923 LPNAMKDSVRGTYSNHSPRR-YIKIRPSDVYRPVGEVL------AEIEEV
: : *. . .
Mb3440|M.bovis_AF2122/97 DFRTEHPVVRVHPETGERTLLAGDFVRSFVGLDSH--ESRVLFEVLQRRI
Rv3406|M.tuberculosis_H37Rv DFRTEHPVVRVHPETGERTLLAGDFVRSFVGLDSH--ESRVLFEVLQRRI
MMAR_1141|M.marinum_M DFRTEHPVVRVHPETGERTLLAGDFVRGFVGLDSQ--ESSALFELLQRRI
MUL_0904|M.ulcerans_Agy99 DFRTEHPVVRVHPETGERTLLAGDFVRGFVGLDSQ--ESSALFELLQRRI
MAB_0086|M.abscessus_ATCC_1997 HFETHHPVVRVHPETGEKALLLGNFVKRILDVSAS--ESQALFRMFQDRV
Mflv_2472|M.gilvum_PYR-GCK RPTHEHPLVWTH-RSGRKSLVLGASAHYVVGMDYD--EGRALLAELLDRA
MAV_3959|M.avium_104 RRTHEHPLVWTH-RSGRKSLVLGASADYVVGMDVD--EGRALLEELLQRA
Mvan_4182|M.vanbaalenii_PYR-1 RPTHEHPLVWTH-RTGRKSLVLGASADYIVGMDPE--EGRALLSELLDRA
TH_0024|M.thermoresistible__bu RPTHEHPLVWTH-RNGRKSLVLGASADYVVGMDLD--EGRALLADLLDRA
MSMEG_0291|M.smegmatis_MC2_155 RPTHENPLVWTH-RNGRKSLVLGASADHIVGMDRD--EGRALLDGLLART
MLBr_01992|M.leprae_Br4923 TPPQKWPTVIKHPKTGQEILYICEAATVSVEDKNGNLLDPMVLQELLTAS
. * * * ..*.. * . : . . :: :
Mb3440|M.bovis_AF2122/97 TMPE------NTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTL
Rv3406|M.tuberculosis_H37Rv TMPE------NTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTL
MMAR_1141|M.marinum_M TSPE------NTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRVTL
MUL_0904|M.ulcerans_Agy99 TSPE------NTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRVTL
MAB_0086|M.abscessus_ATCC_1997 TWLE------NTIRWSWELGDVAMWDNRATQHYAISDYGDQPRRMHRVTL
Mflv_2472|M.gilvum_PYR-GCK TQPE------LVYSHSWSVGDTVIWDNNGVLHRAAPYDPDSQREMLRTTV
MAV_3959|M.avium_104 TVPE------RVYRHGWSIGDTVIWDNRGVLHRAAPYDPDSSREMLRTTV
Mvan_4182|M.vanbaalenii_PYR-1 TTAD------KVYSHHWAVGDTVIWDNRGVLHRAARYDENSPREMLRTTV
TH_0024|M.thermoresistible__bu TTED------RVYRHRWSVGDTVIWDNRGVLHRAAPYPEDSPREMLRTTV
MSMEG_0291|M.smegmatis_MC2_155 TTPD------KVYSHKWSVGDTVIWDNQGVLHRAAPYEPDSPRHMLRTTV
MLBr_01992|M.leprae_Br4923 GQLDPDCKSLLIHTQHYEVGDVVLWDNRALVHRAKHGTVSGTLITYRLTL
: : **..:***.. * * . * *:
Mb3440|M.bovis_AF2122/97 MGDVPVDVYGQASRVISG---------APMEIAG
Rv3406|M.tuberculosis_H37Rv MGDVPVDVYGQASRVISG---------APMEIAG
MMAR_1141|M.marinum_M MGDVPVDVHGQRSRVISG---------APLALAG
MUL_0904|M.ulcerans_Agy99 MGDVPVDVHGQRSRVISG---------APLALAG
MAB_0086|M.abscessus_ATCC_1997 AGDVPVGVNGESSRVIAGDASDYSVIDNPKRLVA
Mflv_2472|M.gilvum_PYR-GCK LGDEPIQ---------------------------
MAV_3959|M.avium_104 LGDEPIQ---------------------------
Mvan_4182|M.vanbaalenii_PYR-1 LGDEPIQ---------------------------
TH_0024|M.thermoresistible__bu LGDEPIQ---------------------------
MSMEG_0291|M.smegmatis_MC2_155 LGDEPIR---------------------------
MLBr_01992|M.leprae_Br4923 LDGLKTPGYAV-----------------------
..