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M. thermoresistible (build 8) TH_0024 (-)

annotation: dioxygenase, TauD/TfdA family protein
coordinates: 65673 - 66518
length: 282

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0024--100% (282)dioxygenase, TauD/TfdA family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3440-3e-2130.63% (284) dioxygenase
M. gilvum PYR-GCKMflv_2472-1e-12779.00% (281) taurine catabolism dioxygenase TauD/TfdA
M. tuberculosis H37RvRv3406-4e-2130.63% (284) dioxygenase
M. leprae Br4923MLBr_01992-4e-0623.64% (275) putative oxidoreductase
M. abscessus ATCC 19977MAB_0086-6e-2528.81% (295) putative taurine dioxygenase
M. marinum MMMAR_1141tauD3e-2332.08% (293) taurine catabolism dioxygenase, TauD
M. avium 104MAV_3959-1e-12878.65% (281) taurine catabolism dioxygenase TauD, TfdA family protein
M. smegmatis MC2 155MSMEG_0291-1e-12173.67% (281) dioxygenase, TauD/TfdA family protein
M. ulcerans Agy99MUL_0904tauD2e-2332.08% (293) taurine catabolism dioxygenase, TauD
M. vanbaalenii PYR-1Mvan_4182-1e-13179.72% (281) taurine catabolism dioxygenase TauD/TfdA

CLUSTAL 2.0.9 multiple sequence alignment


Mb3440|M.bovis_AF2122/97            MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQ
Rv3406|M.tuberculosis_H37Rv         MTDLITVKKLGSRIGAQIDGVRLGGDLDPAAVNEIRAALLAHKVVFFRGQ
MMAR_1141|M.marinum_M               MTDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVIFFRNQ
MUL_0904|M.ulcerans_Agy99           MTDLITVKKLGSRIGAQVDGVSLGADLDAAAVDQIRAALLEHKVIFFRNQ
MAB_0086|M.abscessus_ATCC_1997      MSSDLRVVKLGENIGARIDGVRLG-EVDTATASAINEAMLEHKVVFFRGQ
Mflv_2472|M.gilvum_PYR-GCK          -MSLLTINKLTPSVGAEVLGVDPVRLASDESLAAAVLDALEDNGVLVFPD
MAV_3959|M.avium_104                -MSLLTITKLTDSVGAEVTGLDPAALAHDDSVGEAVLDALEDNGVLVFRG
Mvan_4182|M.vanbaalenii_PYR-1       -MTLLTINKLTSSVGAEVTGLDPGRLAGDDALGTAVLDALEDNGVLVFPG
TH_0024|M.thermoresistible__bu      -MSRLTINRLTASVGAEVTGTTADELAADAALGAAVLDALEEHGVLVFRG
MSMEG_0291|M.smegmatis_MC2_155      -MSVLTINKLTASVGAEVVGIDSERLATDDGIAAAVLDALEDNGVLVFRG
MLBr_01992|M.leprae_Br4923          ----MTLDVKGDGLGAQVTGVDPKNLDSISTAEIRKIVYVN--KLVVLKD
                                        : :      :**.: *                   :    :..   

Mb3440|M.bovis_AF2122/97            HQLDDAEQLAFAGLLGTPIGHPAAIALADDAPIITPINSEFGK-----AN
Rv3406|M.tuberculosis_H37Rv         HQLDDAEQLAFAGLLGTPIGHPAAIALADDAPIITPINSEFGK-----AN
MMAR_1141|M.marinum_M               HHLDDQQQLQFAGLLGTPIGHPAAAAALPDAPIITPINSEWGK-----AN
MUL_0904|M.ulcerans_Agy99           HHLDDQQQLQFAGLLGTPIGHPAAAAALPDAPIITPINSEWGK-----AN
MAB_0086|M.abscessus_ATCC_1997      HHVDDEVQFAFAKSMGIPT-TPHPTLTSSDVKVLPIDSEEGGR-----AN
Mflv_2472|M.gilvum_PYR-GCK          LHLAPEAQVAFSRRLGAVDHSADGHHPVAGIYPVTLDKSKNAS-----AA
MAV_3959|M.avium_104                LYLDPAAQVAFCGRLGEVDHSSDGHHPVPGIYPITLDKSKNAS-----AA
Mvan_4182|M.vanbaalenii_PYR-1       LHLEPEVQVEFCRRLGEIDFSSDGHHRVAGIYPVTLDKSKNSS-----AA
TH_0024|M.thermoresistible__bu      LRIDPQTQVKFCRHLGEVDHSSDGHHPVAGIYPVTLDKSKNSS-----AA
MSMEG_0291|M.smegmatis_MC2_155      LYLEPEAQVAFSQRLGEVDRSADGHHPVSGIYPITLDQTKNKA-----AE
MLBr_01992|M.leprae_Br4923          VHPTPEEFIKLGRIIGEIVPYYEPIYRHKDYPEIFVSSTEEGQGVPNTGA
                                            . :   :*             .   :   . :        . 

Mb3440|M.bovis_AF2122/97            RWHTDVTFAAN---------YPAASVLRAVSLPSYGGSTLWANTAAAYAE
Rv3406|M.tuberculosis_H37Rv         RWHTDVTFAAN---------YPAASVLRAVSLPSYGGSTLWANTAAAYAE
MMAR_1141|M.marinum_M               RWHTDVTFAAN---------YPAASILRAVTLPNYGGSTLWANTATAYAE
MUL_0904|M.ulcerans_Agy99           RWHTDVTFAAN---------YPAASILRAVTLPNYGGSTLWANTATAYAE
MAB_0086|M.abscessus_ATCC_1997      QWHTDVTFVDR---------IPKASILRAVELPPYGGTTTWTSTVAAYRQ
Mflv_2472|M.gilvum_PYR-GCK          YLRATFDWHIDGCTPIGDECPQRATVLSAVQVADRGGETEFANSYAAYEA
MAV_3959|M.avium_104                YLKATFDWHIDGCTPLGDECPQKATVLSAVRVAERGGETEFANSYGAYDA
Mvan_4182|M.vanbaalenii_PYR-1       YLRATFDWHIDGCTPTGDDYPQMATVLSAKQVAESGGETEFASSYAAYDA
TH_0024|M.thermoresistible__bu      YLRATFDWHIDGCTPTGDEYPQKATVLSAVQVADRGGETEFASSYGAYEA
MSMEG_0291|M.smegmatis_MC2_155      YLKATFDWHIDGCTPLNDECPQKATVLSAIEVAARGGETEFANAYAAYES
MLBr_01992|M.leprae_Br4923          FWHVDYIFMPE---------PFAFSMTLPLAMPGHDRGTHFIDLSQVWES
                                      :.   :                ::  .  :.  .  * : .   .:  

Mb3440|M.bovis_AF2122/97            LPEPLKCLTENLWALHTNRYDYVT---TKPLTAAQRA-----FRQVFEKP
Rv3406|M.tuberculosis_H37Rv         LPEPLKCLTENLWALHTNRYDYVT---TKPLTAAQRA-----FRQVFEKP
MMAR_1141|M.marinum_M               LPEPLKCLVENLWALHTNRYDYVANEAVQALTDTQQA-----FRQAFQKP
MUL_0904|M.ulcerans_Agy99           LPEPLKCLVENLWALHTNRYDYVANEAVQALTDTQQA-----FRQAFQKP
MAB_0086|M.abscessus_ATCC_1997      LPKPLQDLADNLWAMHNNQFDYTQVDPAKVAELLAKAGSGSKYVREFGAT
Mflv_2472|M.gilvum_PYR-GCK          FSDEEKERYAALRVVHSLEASQSRVNPDPSPEELARWR-----------S
MAV_3959|M.avium_104                LTDDEKQRFGALRVVHSLEASQRRVYPDPSPELVARWR-----------S
Mvan_4182|M.vanbaalenii_PYR-1       LTDAEKQRFASLRVVHSLEASQRRVNPDPSPEELARWR-----------A
TH_0024|M.thermoresistible__bu      LSEEEKRHVETLRVVHSLEASQRRVTPDPTPEQLARWR-----------A
MSMEG_0291|M.smegmatis_MC2_155      LDADEKQRYARLRVVHSLEASQRRVYPDPTAEQRRRWA-----------A
MLBr_01992|M.leprae_Br4923          LPNAMKDSVRGTYSNHSPRR-YIKIRPSDVYRPVGEVL------AEIEEV
                                    :    :         *. .                .              

Mb3440|M.bovis_AF2122/97            DFRTEHPVVRVHPETGERTLLAGDFVRSFVGLDSH--ESRVLFEVLQRRI
Rv3406|M.tuberculosis_H37Rv         DFRTEHPVVRVHPETGERTLLAGDFVRSFVGLDSH--ESRVLFEVLQRRI
MMAR_1141|M.marinum_M               DFRTEHPVVRVHPETGERTLLAGDFVRGFVGLDSQ--ESSALFELLQRRI
MUL_0904|M.ulcerans_Agy99           DFRTEHPVVRVHPETGERTLLAGDFVRGFVGLDSQ--ESSALFELLQRRI
MAB_0086|M.abscessus_ATCC_1997      HFETHHPVVRVHPETGEKALLLGNFVKRILDVSAS--ESQALFRMFQDRV
Mflv_2472|M.gilvum_PYR-GCK          RPTHEHPLVWTH-RSGRKSLVLGASAHYVVGMDYD--EGRALLAELLDRA
MAV_3959|M.avium_104                RRTHEHPLVWTH-RSGRKSLVLGASADYVVGMDVD--EGRALLEELLQRA
Mvan_4182|M.vanbaalenii_PYR-1       RPTHEHPLVWTH-RTGRKSLVLGASADYIVGMDPE--EGRALLSELLDRA
TH_0024|M.thermoresistible__bu      RPTHEHPLVWTH-RNGRKSLVLGASADYVVGMDLD--EGRALLADLLDRA
MSMEG_0291|M.smegmatis_MC2_155      RPTHENPLVWTH-RNGRKSLVLGASADHIVGMDRD--EGRALLDGLLART
MLBr_01992|M.leprae_Br4923          TPPQKWPTVIKHPKTGQEILYICEAATVSVEDKNGNLLDPMVLQELLTAS
                                        . * *  * ..*.. *     .   :  .     .  ::  :    

Mb3440|M.bovis_AF2122/97            TMPE------NTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTL
Rv3406|M.tuberculosis_H37Rv         TMPE------NTIRWNWAPGDVAIWDNRATQHRAIDDYDDQHRLMHRVTL
MMAR_1141|M.marinum_M               TSPE------NTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRVTL
MUL_0904|M.ulcerans_Agy99           TSPE------NTIRWNWESGDVAIWDNRATQHRAIDDYDDQHRLLHRVTL
MAB_0086|M.abscessus_ATCC_1997      TWLE------NTIRWSWELGDVAMWDNRATQHYAISDYGDQPRRMHRVTL
Mflv_2472|M.gilvum_PYR-GCK          TQPE------LVYSHSWSVGDTVIWDNNGVLHRAAPYDPDSQREMLRTTV
MAV_3959|M.avium_104                TVPE------RVYRHGWSIGDTVIWDNRGVLHRAAPYDPDSSREMLRTTV
Mvan_4182|M.vanbaalenii_PYR-1       TTAD------KVYSHHWAVGDTVIWDNRGVLHRAARYDENSPREMLRTTV
TH_0024|M.thermoresistible__bu      TTED------RVYRHRWSVGDTVIWDNRGVLHRAAPYPEDSPREMLRTTV
MSMEG_0291|M.smegmatis_MC2_155      TTPD------KVYSHKWSVGDTVIWDNQGVLHRAAPYEPDSPRHMLRTTV
MLBr_01992|M.leprae_Br4923          GQLDPDCKSLLIHTQHYEVGDVVLWDNRALVHRAKHGTVSGTLITYRLTL
                                       :            :  **..:***..  * *     .      * *:

Mb3440|M.bovis_AF2122/97            MGDVPVDVYGQASRVISG---------APMEIAG
Rv3406|M.tuberculosis_H37Rv         MGDVPVDVYGQASRVISG---------APMEIAG
MMAR_1141|M.marinum_M               MGDVPVDVHGQRSRVISG---------APLALAG
MUL_0904|M.ulcerans_Agy99           MGDVPVDVHGQRSRVISG---------APLALAG
MAB_0086|M.abscessus_ATCC_1997      AGDVPVGVNGESSRVIAGDASDYSVIDNPKRLVA
Mflv_2472|M.gilvum_PYR-GCK          LGDEPIQ---------------------------
MAV_3959|M.avium_104                LGDEPIQ---------------------------
Mvan_4182|M.vanbaalenii_PYR-1       LGDEPIQ---------------------------
TH_0024|M.thermoresistible__bu      LGDEPIQ---------------------------
MSMEG_0291|M.smegmatis_MC2_155      LGDEPIR---------------------------
MLBr_01992|M.leprae_Br4923          LDGLKTPGYAV-----------------------
                                     ..