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MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADR LYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRI AEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPSTDAERLADACAHALLDAISRLPQIPA ELADAMATARM
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3323 | - | - | 100% (221) | TetR family transcriptional regulator |
| M. bovis AF2122 / 97 | Mb3233 | - | 2e-09 | 26.71% (161) | TetR family transcriptional regulator |
| M. bovis AF2122 / 97 | Mb0163 | - | 6e-09 | 25.39% (193) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4802 | - | 9e-80 | 65.45% (220) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3295 | - | 1e-125 | 100.00% (221) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 1e-107 | 85.45% (220) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3650 | - | 2e-49 | 43.98% (216) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1239 | - | 1e-107 | 86.36% (220) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4266 | - | 1e-102 | 80.09% (221) | hypothetical protein MAV_4266 |
| M. smegmatis MC2 155 | MSMEG_1935 | - | 7e-10 | 31.31% (99) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0452 | - | 3e-10 | 34.41% (93) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2648 | - | 1e-107 | 86.36% (220) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1640 | - | 5e-78 | 62.73% (220) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4802|M.gilvum_PYR-GCK -------------------------MAEARR--RLSPDDRRNELLALGAE
Mvan_1640|M.vanbaalenii_PYR-1 -------------------------MAGPRR--RLSPDERRSELLTLGAE
Mb3323|M.bovis_AF2122/97 -------------------------MATARR--RLSPQDRRAELLALGAE
Rv3295|M.tuberculosis_H37Rv -------------------------MATARR--RLSPQDRRAELLALGAE
MMAR_1239|M.marinum_M -------------------------MATARR--RLSPEDRRAELLALGAE
MUL_2648|M.ulcerans_Agy99 -------------------------MATARR--RLSPEDRRAELLALGAE
MLBr_00717|M.leprae_Br4923 -------------------------MTTARR--RLSPEDRRAELLALGAE
MAV_4266|M.avium_104 -------------------------MATARR--RLSPEDRRAELLALGAE
MAB_3650|M.abscessus_ATCC_1997 --------------MTDDSDAVRPSGASPRR--RLTPEDRRAELLDFGTQ
MSMEG_1935|M.smegmatis_MC2_155 MSDLANTAERRGEKRP---------AGGNRRGNRLPRDERRGQLLIAASE
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
** **. ::** :** .::
Mflv_4802|M.gilvum_PYR-GCK VFGQRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVRAESERLFD
Mvan_1640|M.vanbaalenii_PYR-1 VFGQRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVRAETERLFH
Mb3323|M.bovis_AF2122/97 VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYA
Rv3295|M.tuberculosis_H37Rv VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYA
MMAR_1239|M.marinum_M VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYE
MUL_2648|M.ulcerans_Agy99 VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYE
MLBr_00717|M.leprae_Br4923 VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYA
MAV_4266|M.avium_104 VFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYE
MAB_3650|M.abscessus_ATCC_1997 LFGERHYDDVRMDEVAEQAGVSRALLYRYFPDKRAFYTAVMQAEYDRLYD
MSMEG_1935|M.smegmatis_MC2_155 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
TH_0452|M.thermoresistible__bu VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
:* .* *. . :**:*::****:.::*::*..* :: **:: . :.*
Mflv_4802|M.gilvum_PYR-GCK ATN-TPAQPGQTLFTQVRAGVLAYLRYDELHPHGAWAAYMGMSRSDPVLR
Mvan_1640|M.vanbaalenii_PYR-1 ATN-TPPQPGQTLFAQVRAGVLAYLQYDEHHPHGAWAAYLGMGRSDPLLR
Mb3323|M.bovis_AF2122/97 ATN-KAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL
Rv3295|M.tuberculosis_H37Rv ATN-KAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL
MMAR_1239|M.marinum_M ATS-IESPVGMTMFEEIRLGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL
MUL_2648|M.ulcerans_Agy99 ATS-IESPVGMTMFEEIRLGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLL
MLBr_00717|M.leprae_Br4923 ATN-IPPPAGLTMFEEVRVGVLAYMAYHKQNPEAAWAAYVGLGRSDPVLL
MAV_4266|M.avium_104 NTN-MDDVTGLTMYEEIRVGVLAYMAYHEQNPEAAWAAYVGLGRSDPVLL
MAB_3650|M.abscessus_ATCC_1997 ATISLDMDQTLSGFERLRRTLLVYLHYQEEHPFAPVTVFRMIDSADPTVM
MSMEG_1935|M.smegmatis_MC2_155 GVR-QALRTTTDNRQRLRAAVEAFFDFIEHDSQGYRLIFENDYVTEPQVA
TH_0452|M.thermoresistible__bu GVR-QALRTTTDNRQRLRAAVQAFFDFIEHDGQGYRLIFENDYVTEPQVA
. .:* : .:: : : . . : ::* :
Mflv_4802|M.gilvum_PYR-GCK GIDDHDNDRQANRIIDRVTAGVEP------LDAKVERD-LRAAVYGWLAF
Mvan_1640|M.vanbaalenii_PYR-1 GIEDIDNDRQANRIIDRITTAVGGG-----IDSKLERD-LRATVYGWLAF
Mb3323|M.bovis_AF2122/97 GIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERD-LRVIIHGWLAF
Rv3295|M.tuberculosis_H37Rv GIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERD-LRVIIHGWLAF
MMAR_1239|M.marinum_M GIDDEAKNRQMEHIMTRIGQVVSGIPGSTALDQHVERD-LRVIIYGWLAF
MUL_2648|M.ulcerans_Agy99 GIDDEAKNRQMEHIMTRIGQVVSGIPGSTALDQHVERD-LRVIIYGWLAF
MLBr_00717|M.leprae_Br4923 GIDDEAKNRQMEHIMSRIGDVVSVVP-ESKLHPDIERD-LRVIVHGWLAF
MAV_4266|M.avium_104 GVEDDAKNRQMEHIMSRINQLLAEVP--ATLEPDVERH-LRVILHGWLAF
MAB_3650|M.abscessus_ATCC_1997 AIEQQEYDKQTDRIMAVVDHVAGD-----EMTPALVTD-LKVVIRAWLAF
MSMEG_1935|M.smegmatis_MC2_155 AQVKVATEACTDAVFDLISR-----------DSGLEAHRARMIAVGLVAI
TH_0452|M.thermoresistible__bu AQVKVATEACTDAVFDLISQ-----------DSGLEAHRARMIAVGLVAI
. . : : :: : : . : . :*:
Mflv_4802|M.gilvum_PYR-GCK TFEMCRQRLMDAS-LDADYLGDLCAHALMDALARVPGIPADLAEAVAPDR
Mvan_1640|M.vanbaalenii_PYR-1 TFEMCRQRLMDAS-LDADFIAGLCAHGLMDAVGRVPGIPAALAEAVAVDR
Mb3323|M.bovis_AF2122/97 TFELCRQRIMDPS-TDAERLADACAHALLDAISRLPQIPAELADAMATAR
Rv3295|M.tuberculosis_H37Rv TFELCRQRIMDPS-TDAERLADACAHALLDAISRLPQIPAELADAMATAR
MMAR_1239|M.marinum_M TFEICRQRIMDPG-TDADRLADACAHTLLDSIARVPEIPGELAEAMATAR
MUL_2648|M.ulcerans_Agy99 TFEICRQRIMDPG-TDADRLADACAHTLLDSIARVPEIPGELAEAMATAR
MLBr_00717|M.leprae_Br4923 TFEVCRQRIMDPS-TDADRLADSCAHALLDAIARVPEISKELADAMAIAR
MAV_4266|M.avium_104 TFEICRQRIIDPT-TDADKLADACAHALLDAIGRVPEIPEELGEAMANSR
MAB_3650|M.abscessus_ATCC_1997 NQELARQRALNPE-LDVDWLADTSAHAMIDAVRRMPNIPQAVVDLMGAD-
MSMEG_1935|M.smegmatis_MC2_155 SVDSARYWLNNDRPIDKDSAVEGTVQFAWGGLSHVPLTRS----------
TH_0452|M.thermoresistible__bu SVDCARYWLHADRPISKEDAVEGTVQFAWGGLSHVPLTRS----------
. : .* . : .: ..: ::*
Mflv_4802|M.gilvum_PYR-GCK R---
Mvan_1640|M.vanbaalenii_PYR-1 R---
Mb3323|M.bovis_AF2122/97 M---
Rv3295|M.tuberculosis_H37Rv M---
MMAR_1239|M.marinum_M HTPQ
MUL_2648|M.ulcerans_Agy99 HTPQ
MLBr_00717|M.leprae_Br4923 QPPQ
MAV_4266|M.avium_104 L---
MAB_3650|M.abscessus_ATCC_1997 ----
MSMEG_1935|M.smegmatis_MC2_155 ----
TH_0452|M.thermoresistible__bu ----