For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TDPRLTLESIVGKAIEIADSDGLSGVSMRKIADALGVGAMSLYRHVADKDALLVEMTAEVTRRFAYPDEM MGVPDWRARVRVAVEHDFDLYSTHPWVLLAYAVPRNGMQPETLVCFDWLLEAFSHLGVAAPEAAELTFQV WSYSQGVGLGAVGGQLVSPGARTDFSGLSELIAGNAEVPESPRLAALLGLGDLPEVTNPREVIAKGVEIL CDGIARRYHKL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2957c | - | - | 100% (222) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4687 | - | 7e-09 | 24.74% (194) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1508c | - | 6e-08 | 23.81% (147) | putative HTH-type transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1388c | - | 2e-06 | 25.82% (213) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_2560 | - | 2e-13 | 34.92% (126) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1353c | - | 2e-06 | 25.82% (213) | transcriptional regulatory protein |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_3679 | - | 5e-13 | 27.49% (211) | putative regulatory protein |
| M. avium 104 | MAV_5055 | - | 2e-10 | 30.43% (184) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3332 | - | 2e-12 | 28.76% (226) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1116 | - | 3e-07 | 33.78% (74) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN |
| M. ulcerans Agy99 | MUL_3622 | - | 3e-13 | 27.49% (211) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1315 | - | 2e-15 | 38.89% (126) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3679|M.marinum_M ---------------------------MFTLRTMYLSTVWEGDVRA---R
MUL_3622|M.ulcerans_Agy99 -------------------MISIRTSYVFTLRTMYLSTVWEGDVRA---R
Mb1388c|M.bovis_AF2122/97 --------------------------------MQTTPGKRQRRQRG---S
Rv1353c|M.tuberculosis_H37Rv --------------------------------MQTTPGKRQRRQRG---S
TH_1116|M.thermoresistible__bu ------------------------------VAKQATADKRRRRERG---S
Mflv_2560|M.gilvum_PYR-GCK MTSLPPATIGRMDNPGSGSARSSAGDPVRTLELLWRVPAEARSGRGPKQR
MSMEG_3332|M.smegmatis_MC2_155 ----------------------MTQPPAGPSGPGDSAPSADATENGQNRP
MAV_5055|M.avium_104 -----------------------------------------MRRAG----
Mvan_1315|M.vanbaalenii_PYR-1 -----MSYAHGCTAVRLDRMTNEEERGTPPLPRALEVLWHDRAGGGRARR
MAB_2957c|M.abscessus_ATCC_199 ----------------------------------------MTDPR-----
MMAR_3679|M.marinum_M FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEA
MUL_3622|M.ulcerans_Agy99 FTVSDIASAALAIVDQDGLSGLSMRSLAAALGTGPMTLYNYVRDRRELEA
Mb1388c|M.bovis_AF2122/97 INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLN
Rv1353c|M.tuberculosis_H37Rv INPEDIISGAFELAQQVSIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLN
TH_1116|M.thermoresistible__bu INPDDIVAGAFELAEEVGIDNLSMPLLGKHLGVGVTSIYWYFRKKDDLLN
Mflv_2560|M.gilvum_PYR-GCK TSVDAVVAAAVGIADTQGLSAVTIRAVAGVLGLAPMAIYTYVPGKAELLD
MSMEG_3332|M.smegmatis_MC2_155 ITREAVLAGALDIIDRDGVDALSMRRLGEALGRDPMALYRHVPNKAAVLD
MAV_5055|M.avium_104 LKREAVVRAAVKIADAEGIEAISMRRVSQALGVTPMALYRYLPDKDALID
Mvan_1315|M.vanbaalenii_PYR-1 LSRQRIVEAAIELADRDGLGALSMARLAERLGCGTMSLYRHVANKDELVT
MAB_2957c|M.abscessus_ATCC_199 LTLESIVGKAIEIADSDGLSGVSMRKIADALGVGAMSLYRHVADKDALLV
. . : *. : : .: ::: :. ** ::* :. : :
MMAR_3679|M.marinum_M LVADAVVADVKVPAP---TDDWRADVHAIATAMWETMRQHPNAIPLVLTR
MUL_3622|M.ulcerans_Agy99 LVADAVVADVKVPAP---IDDWRADVHAIATAMWETMRQHPNAIPLVLTR
Mb1388c|M.bovis_AF2122/97 AMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR
Rv1353c|M.tuberculosis_H37Rv AMTDRALSKYVFATPYIEAGDWRETLRNHARSMRKTFADNPVLCDLILIR
TH_1116|M.thermoresistible__bu EMTNRALRQYVFETPYVEAGNWRESLRNHARNMRKTFLSSPILTDLVLIR
Mflv_2560|M.gilvum_PYR-GCK LMLDSVYGQMSRGDLS--GLPWRHRVTAIADENRALLDEHPWVTQLATTR
MSMEG_3332|M.smegmatis_MC2_155 GVVEMIFEQLSLDTT---TPDWIAALRRLGHDFRNLARAHPNVVPLLVTR
MAV_5055|M.avium_104 VVVDESLAVVPVPDP---SGSVTAELLRCFGGLYDLLLDHPGLARAAGER
Mvan_1315|M.vanbaalenii_PYR-1 FMVSAAPGHPPGTTDR---ADWRDALTDWAVGLWDVYHRHPWILHATVIG
MAB_2957c|M.abscessus_ATCC_199 EMTAEVTRRFAYPDEMMGVPDWRARVRVAVEHDFDLYSTHPWVLLAYAVP
: : *
MMAR_3679|M.marinum_M RTVSASSYMV------ADRLIAALGRSGVGDADLLASFRGVLGLVMGSAQ
MUL_3622|M.ulcerans_Agy99 RTVWASSYMV------ADRLIAALGRSGVGDADLLASFRGVLGLVMGSAQ
Mb1388c|M.bovis_AF2122/97 AALSPKTARLG--AQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVV
Rv1353c|M.tuberculosis_H37Rv AALSPKTARLG--AQEMEKAIANLVTAGLSLEDAFDIYSAVSVHVRGSVV
TH_1116|M.thermoresistible__bu GALNTKIRKLG--LQQMEAAIDSLVQAGLSPEDAFDTYSAVSVHVRGSVV
Mflv_2560|M.gilvum_PYR-GCK PPLGPGTAAK------YDHELRAFDGLGLSDLDMDSALTYVLGFVTSVAR
MSMEG_3332|M.smegmatis_MC2_155 PLATPLGMRPPGILRHLEQILALLTRCGFTGPDALHVYRTLFGFLYGHVL
MAV_5055|M.avium_104 PLEGPFATRLG------NNVLTLLQHNKIDEADAANLLVSAFSLTLGCAL
Mvan_1315|M.vanbaalenii_PYR-1 PPADPGQLAWL------DAGLAALSGTGLSERDKLAAVMALLHFVRGASA
MAB_2957c|M.abscessus_ATCC_199 RNGMQPETLVC-----FDWLLEAFSHLGVAAPEAAELTFQVWSYSQGVGL
: : : . : .
MMAR_3679|M.marinum_M AELAGPLAGTGREKEQVAVAARIGGLAGAEHP--------HIAALAQASQ
MUL_3622|M.ulcerans_Agy99 AELAGPLAGTGREKEQVAVAARIGGLAGAEHP--------HIAALAQASQ
Mb1388c|M.bovis_AF2122/97 LDRLS--RKSQSAGSGPSAIEHPVAIDPATTP--------LLAHATGRGH
Rv1353c|M.tuberculosis_H37Rv LDRLS--RKSQSAGSGPSAIEHPVAIDPATTP--------LLAHATGRGH
TH_1116|M.thermoresistible__bu LERLH--EKTQDLFNGG---DEPSAVDPASTP--------IIAELLAKGH
Mflv_2560|M.gilvum_PYR-GCK IADDAREARRDSGVSDQAWWDRAGPLLAEVFDDEKFPLAARIGAAAGQAF
MSMEG_3332|M.smegmatis_MC2_155 TELQEIVERPEE--TDHVMRLGLHRLPIGEFP--------HVRDLAPT--
MAV_5055|M.avium_104 YRTSRSGRTASSRLSQVGDEAPAVRRLRGRLT------------------
Mvan_1315|M.vanbaalenii_PYR-1 LDIEAADHHDTAPDYPALLRRLVTGERFPALA----------AALQAEAF
MAB_2957c|M.abscessus_ATCC_199 GAVGGQLVSPGARTDFSGLSELIAGNAEVPES------PRLAALLGLGDL
MMAR_3679|M.marinum_M RSTPAAD--FERALDILLAGIESFERRRDRR-------------------
MUL_3622|M.ulcerans_Agy99 RSTPAAD--FERALDILLAGIESFERRRDRR-------------------
Mb1388c|M.bovis_AF2122/97 RIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPG
Rv1353c|M.tuberculosis_H37Rv RIGAPDETNFEYGLECILDHAGRLIEQSSKAAGEVAVRRPTATADAPTPG
TH_1116|M.thermoresistible__bu RLAEADERNFEYTLECILDHAERLIEER--AAG----------------G
Mflv_2560|M.gilvum_PYR-GCK GSAYDADHAYRFGLARVLDGLEPVINRTAR--------------------
MSMEG_3332|M.smegmatis_MC2_155 WAAYDGLAELDRGLDILLTGLATRLDMPGGMPTRAPEPG-----------
MAV_5055|M.avium_104 -VASADDTVFRDALTRLIAGYVTTAAKTGGRRR-----------------
Mvan_1315|M.vanbaalenii_PYR-1 DADGDRLADFRSGLDQFLDGIDSRVRRSR---------------------
MAB_2957c|M.abscessus_ATCC_199 PEVTNPREVIAKGVEILCDGIARRYHKL----------------------
: .
MMAR_3679|M.marinum_M --------
MUL_3622|M.ulcerans_Agy99 --------
Mb1388c|M.bovis_AF2122/97 ARAKAVAR
Rv1353c|M.tuberculosis_H37Rv ARAKAVAR
TH_1116|M.thermoresistible__bu TRK-----
Mflv_2560|M.gilvum_PYR-GCK --------
MSMEG_3332|M.smegmatis_MC2_155 --------
MAV_5055|M.avium_104 --------
Mvan_1315|M.vanbaalenii_PYR-1 --------
MAB_2957c|M.abscessus_ATCC_199 --------