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M. gilvum PYR-GCK Mflv_3021 (-)

annotation: TetR family transcriptional regulator
coordinates: 3201636 - 3202268
length: 210

VCVVSDPRSDPPSAPLKSRRTAREAQLLTITLQQLQQHGYDRLTVEAVATQAKASKATLYRRWPSKSDLV
LAAFVEGTRLAAVPPRTGSLRDDLLRVGASVCQQACEHASTMRAVLNEMSHNPDLRKAMQDEFVHQHKLV
IDEVLAEAVQRGEIDATAISDEIYDLLPGYLVFRALVSARPPTLKSVRTLVDKVLLPSLGHRGLSKPDGQ
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. gilvum PYR-GCKMflv_3021--100% (210)TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_3683-3e-1729.67% (182) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_5054-2e-1236.80% (125) TetR family transcriptional regulator

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1581-7e-6158.64% (191) regulatory protein
M. tuberculosis H37RvRv1556-7e-6158.64% (191) regulatory protein
M. leprae Br4923MLBr_02568-2e-0538.00% (50) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_0989-6e-5657.14% (182) putative HTH-type transcriptional regulator TetR
M. marinum MMMAR_1695-2e-5859.89% (177) regulatory protein
M. avium 104MAV_3866-4e-5858.89% (180) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_3319-1e-1730.60% (183) repressor protein
M. thermoresistible (build 8)TH_2910-2e-1328.28% (198) PUTATIVE transcriptional regulator, TetR family
M. ulcerans Agy99MUL_1934-1e-5859.89% (177) regulatory protein
M. vanbaalenii PYR-1Mvan_2727-2e-1831.69% (183) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb1581|M.bovis_AF2122/97            --------MVGAVTQ---IADRPTDPSPWSPRETELLAVTLRLLQEHGYD
Rv1556|M.tuberculosis_H37Rv         --------MVGAVTQ---IADRPTDPSPWSPRETELLAVTLRLLQEHGYD
MMAR_1695|M.marinum_M               ------------MTQ---TADRSAQVSPWSPREAELLAVTLQLLQEHGYD
MUL_1934|M.ulcerans_Agy99           ---------MGAMTQ---TADRSAQVSPWSPREAELLAVTLQLLQEHGYD
MAV_3866|M.avium_104                ------------MTQ---TADRCEQASPWSPREAEILAVTLRLLQEHGYD
MAB_0989|M.abscessus_ATCC_1997      --------MASDVSTGLTKAARGRQVSQWTPREVELLKVTLRLLQEHGYD
Mflv_3021|M.gilvum_PYR-GCK          ---------MCVVSDPRSDPPSAPLKSRRTAREAQLLTITLQQLQQHGYD
Mvan_2727|M.vanbaalenii_PYR-1       -----------------------MGRRRGAELDAAIRAAVLELLAEHGPD
MSMEG_3319|M.smegmatis_MC2_155      -----------------------MQRRRGSALESAILDAGWDQLIEAGYD
TH_2910|M.thermoresistible__bu      MAAVDPAEPSARGSDDAVDDDDVDVDPRKLRSRARLLDAATSLLTSGGVE
MLBr_02568|M.leprae_Br4923          -------------------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYH
                                                                       :       :   * .

Mb1581|M.bovis_AF2122/97            RLTVDAVAASARASKATVYRRWPSKAELVLAAFIEG-IRQVAVPPNTGNL
Rv1556|M.tuberculosis_H37Rv         RLTVDAVAASARASKATVYRRWPSKAELVLAAFIEG-IRQVAVPPNTGNL
MMAR_1695|M.marinum_M               RLTIDAVANTARASKATVYRRWPSKAELVLAAFIEG-VRQVAVAPNTGSL
MUL_1934|M.ulcerans_Agy99           RLTIDAVANTARASKATVYRRWPSKAELVLAAFIEG-VRQVAVAPNTGSL
MAV_3866|M.avium_104                QLTVDAVAGAAHASKATVYRRWPSKAELVLAAFIEG-VRQVAVPPNTGTL
MAB_0989|M.abscessus_ATCC_1997      RLSVDEVAAESKASKATIYRRWPSKAELVLAAFIEG-MRAQLVRPNTGSL
Mflv_3021|M.gilvum_PYR-GCK          RLTVEAVATQAKASKATLYRRWPSKSDLVLAAFVEG-TRLAAVPPRTGSL
Mvan_2727|M.vanbaalenii_PYR-1       GVTMDAVAVTAQTSKPVLYRRWPDRRALLRDTLLGI-ATSAFPTVDTGGF
MSMEG_3319|M.smegmatis_MC2_155      GFTIEAVATRSGSARSVLYRRWPSRLDLLKAVIRHRGEIDRIPVPDTGTL
TH_2910|M.thermoresistible__bu      AVTVDAVTRLSKVARTTLYRHFESTTHLLAEAFERL-LPQVTSPPATGDL
MLBr_02568|M.leprae_Br4923          KTSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDF
                                      ::: ::  :  ::. :*  : .   *.   :                :

Mb1581|M.bovis_AF2122/97            RDDLLRLG-ELICREVGQHASTIRAVLVEVSRNPALND-----VLQHQFV
Rv1556|M.tuberculosis_H37Rv         RDDLLRLG-ELICREVGQHASTIRAVLVEVSRNPALND-----VLQHQFV
MMAR_1695|M.marinum_M               RDDLVKIG-EGICGQAHQQASTIRAVLVEVSRHPALSD-----ALQRQFV
MUL_1934|M.ulcerans_Agy99           RDDLVKIG-EGICGQAHQQASTIRAVLVEVSRHPALSD-----ALQRQFV
MAV_3866|M.avium_104                RGDLLALG-ETVCEQVGHHASTIRAVMFEVSRHPALND-----ALQHQFL
MAB_0989|M.abscessus_ATCC_1997      REDLLRIG-TNALADVRRNTPVMRGLLIEIERNPALTK-----AFRTKFV
Mflv_3021|M.gilvum_PYR-GCK          RDDLLRVG-ASVCQQACEHASTMRAVLNEMSHNPDLRK-----AMQDEFV
Mvan_2727|M.vanbaalenii_PYR-1       RGDMLAVLRAWAALFTGDSAALMRSAIGAVTADPELAA-----TFRTDVI
MSMEG_3319|M.smegmatis_MC2_155      RDDVVAVLTEFNDRRSRIIGIIAARLGAYFDEPDGSPK-----QLRDLFL
TH_2910|M.thermoresistible__bu      RDQLIELVHRQAALIDEAPLHLTALAWLALGPDPNSDARQPLAGLSARVI
MLBr_02568|M.leprae_Br4923          TQSPKDLLRNTIVSFLRYIDANRASWIVMYIQAMSLPA----FAQTVREA
                                      .   :                                           

Mb1581|M.bovis_AF2122/97            DHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQ
Rv1556|M.tuberculosis_H37Rv         DHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQ
MMAR_1695|M.marinum_M               DQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTP
MUL_1934|M.ulcerans_Agy99           DQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTP
MAV_3866|M.avium_104                DQRRALIEHVLHQAVDRGEISADAISDELWDLLPGYLIFRSIVPTRPPSR
MAB_0989|M.abscessus_ATCC_1997      DERKALIDDVLFAAVQRGEIDADAVNEELWDLLPGYLVFRSLLPVRSPTA
Mflv_3021|M.gilvum_PYR-GCK          HQHKLVIDEVLAEAVQRGEIDATAISDEIYDLLPGYLVFRALVSARPPTL
Mvan_2727|M.vanbaalenii_PYR-1       GARKQEMDAIITRGVQRGEVRADVPVDLVRELGQSVLWHRLLISGDPIDD
MSMEG_3319|M.smegmatis_MC2_155      SDGPTAMETIVERAVQRGELAAVPP-ARIVSLPADLVRHELLMTMTAVPA
TH_2910|M.thermoresistible__bu      EQYRQPFDELLAGAAARDELDDFDTTLAIIQLLG-PIVFAKLTGMKTLTP
MLBr_02568|M.leprae_Br4923          RDQITELVAGLMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAV
                                          :   :     *..            *                  

Mb1581|M.bovis_AF2122/97            DTVQALVDDVILP-----SLTRSTG------
Rv1556|M.tuberculosis_H37Rv         DTVQALVDDVILP-----SLTRSTG------
MMAR_1695|M.marinum_M               HTVQLLVDDFIMP-----GLTQATG------
MUL_1934|M.ulcerans_Agy99           HTVQLLVDDFIMP-----GLTQATG------
MAV_3866|M.avium_104                RTVQALVDGFLIP-----GLTAR--------
MAB_0989|M.abscessus_ATCC_1997      DTVRTLVDDVIMP-----SLTRER-------
Mflv_3021|M.gilvum_PYR-GCK          KSVRTLVDKVLLPSLGHRGLSKPDGQ-----
Mvan_2727|M.vanbaalenii_PYR-1       EVVTRLVDEVLIP------VTRPYYEV----
MSMEG_3319|M.smegmatis_MC2_155      DTIREIVDDIFLP-----LATRSGQER----
TH_2910|M.thermoresistible__bu      ADRVRIVDDFLVAHR---PPTPETA------
MLBr_02568|M.leprae_Br4923          DEAAELMINLFWHGLKGAPADRDFGPSIVAG
                                         ::  .: