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VCVVSDPRSDPPSAPLKSRRTAREAQLLTITLQQLQQHGYDRLTVEAVATQAKASKATLYRRWPSKSDLV LAAFVEGTRLAAVPPRTGSLRDDLLRVGASVCQQACEHASTMRAVLNEMSHNPDLRKAMQDEFVHQHKLV IDEVLAEAVQRGEIDATAISDEIYDLLPGYLVFRALVSARPPTLKSVRTLVDKVLLPSLGHRGLSKPDGQ
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_3021 | - | - | 100% (210) | TetR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_3683 | - | 3e-17 | 29.67% (182) | TetR family transcriptional regulator |
M. gilvum PYR-GCK | Mflv_5054 | - | 2e-12 | 36.80% (125) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1581 | - | 7e-61 | 58.64% (191) | regulatory protein |
M. tuberculosis H37Rv | Rv1556 | - | 7e-61 | 58.64% (191) | regulatory protein |
M. leprae Br4923 | MLBr_02568 | - | 2e-05 | 38.00% (50) | putative TetR-family transcriptional regulator |
M. abscessus ATCC 19977 | MAB_0989 | - | 6e-56 | 57.14% (182) | putative HTH-type transcriptional regulator TetR |
M. marinum M | MMAR_1695 | - | 2e-58 | 59.89% (177) | regulatory protein |
M. avium 104 | MAV_3866 | - | 4e-58 | 58.89% (180) | transcriptional regulator, TetR family protein |
M. smegmatis MC2 155 | MSMEG_3319 | - | 1e-17 | 30.60% (183) | repressor protein |
M. thermoresistible (build 8) | TH_2910 | - | 2e-13 | 28.28% (198) | PUTATIVE transcriptional regulator, TetR family |
M. ulcerans Agy99 | MUL_1934 | - | 1e-58 | 59.89% (177) | regulatory protein |
M. vanbaalenii PYR-1 | Mvan_2727 | - | 2e-18 | 31.69% (183) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment Mb1581|M.bovis_AF2122/97 --------MVGAVTQ---IADRPTDPSPWSPRETELLAVTLRLLQEHGYD Rv1556|M.tuberculosis_H37Rv --------MVGAVTQ---IADRPTDPSPWSPRETELLAVTLRLLQEHGYD MMAR_1695|M.marinum_M ------------MTQ---TADRSAQVSPWSPREAELLAVTLQLLQEHGYD MUL_1934|M.ulcerans_Agy99 ---------MGAMTQ---TADRSAQVSPWSPREAELLAVTLQLLQEHGYD MAV_3866|M.avium_104 ------------MTQ---TADRCEQASPWSPREAEILAVTLRLLQEHGYD MAB_0989|M.abscessus_ATCC_1997 --------MASDVSTGLTKAARGRQVSQWTPREVELLKVTLRLLQEHGYD Mflv_3021|M.gilvum_PYR-GCK ---------MCVVSDPRSDPPSAPLKSRRTAREAQLLTITLQQLQQHGYD Mvan_2727|M.vanbaalenii_PYR-1 -----------------------MGRRRGAELDAAIRAAVLELLAEHGPD MSMEG_3319|M.smegmatis_MC2_155 -----------------------MQRRRGSALESAILDAGWDQLIEAGYD TH_2910|M.thermoresistible__bu MAAVDPAEPSARGSDDAVDDDDVDVDPRKLRSRARLLDAATSLLTSGGVE MLBr_02568|M.leprae_Br4923 -------------------MAGGAKRIPRAVREQQMLDAAVQMFSVNGYH : : * . Mb1581|M.bovis_AF2122/97 RLTVDAVAASARASKATVYRRWPSKAELVLAAFIEG-IRQVAVPPNTGNL Rv1556|M.tuberculosis_H37Rv RLTVDAVAASARASKATVYRRWPSKAELVLAAFIEG-IRQVAVPPNTGNL MMAR_1695|M.marinum_M RLTIDAVANTARASKATVYRRWPSKAELVLAAFIEG-VRQVAVAPNTGSL MUL_1934|M.ulcerans_Agy99 RLTIDAVANTARASKATVYRRWPSKAELVLAAFIEG-VRQVAVAPNTGSL MAV_3866|M.avium_104 QLTVDAVAGAAHASKATVYRRWPSKAELVLAAFIEG-VRQVAVPPNTGTL MAB_0989|M.abscessus_ATCC_1997 RLSVDEVAAESKASKATIYRRWPSKAELVLAAFIEG-MRAQLVRPNTGSL Mflv_3021|M.gilvum_PYR-GCK RLTVEAVATQAKASKATLYRRWPSKSDLVLAAFVEG-TRLAAVPPRTGSL Mvan_2727|M.vanbaalenii_PYR-1 GVTMDAVAVTAQTSKPVLYRRWPDRRALLRDTLLGI-ATSAFPTVDTGGF MSMEG_3319|M.smegmatis_MC2_155 GFTIEAVATRSGSARSVLYRRWPSRLDLLKAVIRHRGEIDRIPVPDTGTL TH_2910|M.thermoresistible__bu AVTVDAVTRLSKVARTTLYRHFESTTHLLAEAFERL-LPQVTSPPATGDL MLBr_02568|M.leprae_Br4923 KTSMDAIAAEAQISKPMLYLYYGSKEDLFGACLNREMSRFIAMVRADIDF ::: :: : ::. :* : . *. : : Mb1581|M.bovis_AF2122/97 RDDLLRLG-ELICREVGQHASTIRAVLVEVSRNPALND-----VLQHQFV Rv1556|M.tuberculosis_H37Rv RDDLLRLG-ELICREVGQHASTIRAVLVEVSRNPALND-----VLQHQFV MMAR_1695|M.marinum_M RDDLVKIG-EGICGQAHQQASTIRAVLVEVSRHPALSD-----ALQRQFV MUL_1934|M.ulcerans_Agy99 RDDLVKIG-EGICGQAHQQASTIRAVLVEVSRHPALSD-----ALQRQFV MAV_3866|M.avium_104 RGDLLALG-ETVCEQVGHHASTIRAVMFEVSRHPALND-----ALQHQFL MAB_0989|M.abscessus_ATCC_1997 REDLLRIG-TNALADVRRNTPVMRGLLIEIERNPALTK-----AFRTKFV Mflv_3021|M.gilvum_PYR-GCK RDDLLRVG-ASVCQQACEHASTMRAVLNEMSHNPDLRK-----AMQDEFV Mvan_2727|M.vanbaalenii_PYR-1 RGDMLAVLRAWAALFTGDSAALMRSAIGAVTADPELAA-----TFRTDVI MSMEG_3319|M.smegmatis_MC2_155 RDDVVAVLTEFNDRRSRIIGIIAARLGAYFDEPDGSPK-----QLRDLFL TH_2910|M.thermoresistible__bu RDQLIELVHRQAALIDEAPLHLTALAWLALGPDPNSDARQPLAGLSARVI MLBr_02568|M.leprae_Br4923 TQSPKDLLRNTIVSFLRYIDANRASWIVMYIQAMSLPA----FAQTVREA . : Mb1581|M.bovis_AF2122/97 DHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQ Rv1556|M.tuberculosis_H37Rv DHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSIIPNRPPTQ MMAR_1695|M.marinum_M DQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTP MUL_1934|M.ulcerans_Agy99 DQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSIIPNRPPTP MAV_3866|M.avium_104 DQRRALIEHVLHQAVDRGEISADAISDELWDLLPGYLIFRSIVPTRPPSR MAB_0989|M.abscessus_ATCC_1997 DERKALIDDVLFAAVQRGEIDADAVNEELWDLLPGYLVFRSLLPVRSPTA Mflv_3021|M.gilvum_PYR-GCK HQHKLVIDEVLAEAVQRGEIDATAISDEIYDLLPGYLVFRALVSARPPTL Mvan_2727|M.vanbaalenii_PYR-1 GARKQEMDAIITRGVQRGEVRADVPVDLVRELGQSVLWHRLLISGDPIDD MSMEG_3319|M.smegmatis_MC2_155 SDGPTAMETIVERAVQRGELAAVPP-ARIVSLPADLVRHELLMTMTAVPA TH_2910|M.thermoresistible__bu EQYRQPFDELLAGAAARDELDDFDTTLAIIQLLG-PIVFAKLTGMKTLTP MLBr_02568|M.leprae_Br4923 RDQITELVAGLMRVGTRSSRPDHEYEIMAGALVGAGEAMATRLTTGDIAV : : *.. * Mb1581|M.bovis_AF2122/97 DTVQALVDDVILP-----SLTRSTG------ Rv1556|M.tuberculosis_H37Rv DTVQALVDDVILP-----SLTRSTG------ MMAR_1695|M.marinum_M HTVQLLVDDFIMP-----GLTQATG------ MUL_1934|M.ulcerans_Agy99 HTVQLLVDDFIMP-----GLTQATG------ MAV_3866|M.avium_104 RTVQALVDGFLIP-----GLTAR-------- MAB_0989|M.abscessus_ATCC_1997 DTVRTLVDDVIMP-----SLTRER------- Mflv_3021|M.gilvum_PYR-GCK KSVRTLVDKVLLPSLGHRGLSKPDGQ----- Mvan_2727|M.vanbaalenii_PYR-1 EVVTRLVDEVLIP------VTRPYYEV---- MSMEG_3319|M.smegmatis_MC2_155 DTIREIVDDIFLP-----LATRSGQER---- TH_2910|M.thermoresistible__bu ADRVRIVDDFLVAHR---PPTPETA------ MLBr_02568|M.leprae_Br4923 DEAAELMINLFWHGLKGAPADRDFGPSIVAG :: .: