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MTKNAATQRQRTSGRLNRSLDIAILEAAFVTLAEQGYDAMSMDNIAARAGVGKAAIYRRWSSKAALTADA ILHGRPSLGKLDEVPDTGSLRGDLHSLYEARDFGDDQVLTGNLLAGIIAEAVNDPTLAAALDDLLVSQTH KRMELVFARAVERGEITQGRDLSLVYDIPLGLSLTAALKRTVIDETYMHRMVEEVILPLVQAPTTHT
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3151 | - | - | 100% (207) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1497c | - | 2e-16 | 32.96% (179) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0989 | - | 1e-14 | 31.35% (185) | putative HTH-type transcriptional regulator TetR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1581 | - | 3e-15 | 28.80% (184) | regulatory protein |
| M. gilvum PYR-GCK | Mflv_4384 | - | 1e-17 | 34.08% (179) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1556 | - | 3e-15 | 28.80% (184) | regulatory protein |
| M. leprae Br4923 | MLBr_00815 | - | 4e-05 | 40.30% (67) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_1695 | - | 5e-15 | 31.32% (182) | regulatory protein |
| M. avium 104 | MAV_4754 | - | 4e-46 | 48.45% (194) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0465 | - | 3e-44 | 46.91% (194) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4110 | - | 4e-15 | 34.29% (175) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_1934 | - | 3e-15 | 31.32% (182) | regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_1961 | - | 2e-19 | 32.57% (175) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4754|M.avium_104 --------------MGQPQSQMEPESKLRQRTEGRLDRSRDPAILDAALA
MSMEG_0465|M.smegmatis_MC2_155 --------------------MKATDSKLRQRTDGRLDRTRDPAILDAALA
MAB_3151|M.abscessus_ATCC_1997 --------------------MTKNAATQRQRTSGRLNRSLDIAILEAAFV
Mflv_4384|M.gilvum_PYR-GCK ----------MPSVVSVTESYVTLSIVMTTDIGRPRNRAIADAVLRATVE
Mvan_1961|M.vanbaalenii_PYR-1 -------------------------------MGRPRNRAIDDAVLRATVE
Mb1581|M.bovis_AF2122/97 -------------------MVGAVTQIADRPTDPSPWSPRETELLAVTLR
Rv1556|M.tuberculosis_H37Rv -------------------MVGAVTQIADRPTDPSPWSPRETELLAVTLR
MMAR_1695|M.marinum_M -----------------------MTQTADRSAQVSPWSPREAELLAVTLQ
MUL_1934|M.ulcerans_Agy99 --------------------MGAMTQTADRSAQVSPWSPREAELLAVTLQ
TH_4110|M.thermoresistible__bu -----------------VTATDAAATGRAAARGRPRDPALDSAILDAALE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
:* .:
MAV_4754|M.avium_104 ALAEHGYDATNMNDIAARAGVGKAAIYRRWSSKAALMTDALIYWRPEL-L
MSMEG_0465|M.smegmatis_MC2_155 ALAENGYAGTNMDDIASRAGVGKAAIYRRWSSKAALITDALVYWKPAL-L
MAB_3151|M.abscessus_ATCC_1997 TLAEQGYDAMSMDNIAARAGVGKAAIYRRWSSKAALTADAILHGRPSLGK
Mflv_4384|M.gilvum_PYR-GCK LLAESSYAELSLDAVAARAGTSKPAIYRRWRGKAHLVHEAVFPLGADT--
Mvan_1961|M.vanbaalenii_PYR-1 LISESSYAELSLDAIAARAGTSKPAIYRRWRGKAHLVHEAVFPVDATI--
Mb1581|M.bovis_AF2122/97 LLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQV--
Rv1556|M.tuberculosis_H37Rv LLQEHGYDRLTVDAVAASARASKATVYRRWPSKAELVLAAFIEGIRQV--
MMAR_1695|M.marinum_M LLQEHGYDRLTIDAVANTARASKATVYRRWPSKAELVLAAFIEGVRQV--
MUL_1934|M.ulcerans_Agy99 LLQEHGYDRLTIDAVANTARASKATVYRRWPSKAELVLAAFIEGVRQV--
TH_4110|M.thermoresistible__bu IFVEQGISALSIEQVARRAGVGKPTIYRRWSDKEQLVADAIEHRVSAELA
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
: : . :: :* * ..*..:*::: .* * ..
MAV_4754|M.avium_104 NDDAPDT--GSLAGDLDAIVKRAKRNDNALISNDLVLRVALEAAHDPELA
MSMEG_0465|M.smegmatis_MC2_155 IDDIPDT--GSLEGDLNEIAERAARNADERITYDLILRVAVEAMNDSQLA
MAB_3151|M.abscessus_ATCC_1997 LDEVPDT--GSLRGDLHSLYEARDFGDDQVLTGNLLAGIIAEAVNDPTLA
Mflv_4384|M.gilvum_PYR-GCK --AIPGS--GSLEADVREMTRRTLAVLSTPAALAALPGLVGEMASDPTLH
Mvan_1961|M.vanbaalenii_PYR-1 --EIPRT--GSLHGDVREMLRRTLAVLSTPAARAALPGLVGEMASDPTLH
Mb1581|M.bovis_AF2122/97 -AVPPNT--GNLRDDLLRLGELICREVGQHAS--TIRAVLVEVSRNPALN
Rv1556|M.tuberculosis_H37Rv -AVPPNT--GNLRDDLLRLGELICREVGQHAS--TIRAVLVEVSRNPALN
MMAR_1695|M.marinum_M -AVAPNT--GSLRDDLVKIGEGICGQAHQQAS--TIRAVLVEVSRHPALS
MUL_1934|M.ulcerans_Agy99 -AVAPNT--GSLRDDLVKIGEGICGQAHQQAS--TIRAVLVEVSRHPALS
TH_4110|M.thermoresistible__bu WPTPAEASVSDPYELVRRNISAAARTAADPAFRGLIAAIYGSAVTHPALL
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQ--GYRLIFENDNITEPRV
. . : : .
MAV_4754|M.avium_104 TALNDLILFKGRRVLSAVLAQAADRGEIDPNRDWSLVADVLTAMGLLRAI
MSMEG_0465|M.smegmatis_MC2_155 SALDDLTLLRGRRTMTAILKNATARGEIAPDTDWSLVPDVLTAMLLMRAI
MAB_3151|M.abscessus_ATCC_1997 AALDDLLVSQTHKRMELVFARAVERGEITQGRDLSLVYDIPLGLSLTAAL
Mflv_4384|M.gilvum_PYR-GCK TALLERFGDILVRGLTEFLESAVRRGDVRPDVTASDLAEAVAGMTLLALL
Mvan_1961|M.vanbaalenii_PYR-1 AALLERFADVLVRDLNNYLDSAVRRGEVRRGVTAVELAEAVTGMTLLALI
Mb1581|M.bovis_AF2122/97 DVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSI
Rv1556|M.tuberculosis_H37Rv DVLQHQFVDHRKALIQYILQQAVDRGEISSAAISDELWDLLPGYLIFRSI
MMAR_1695|M.marinum_M DALQRQFVDQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSI
MUL_1934|M.ulcerans_Agy99 DALQRQFVDQRKALIQQVLQQAVDRGEITQAAITDELWDLLPGYLIFRSI
TH_4110|M.thermoresistible__bu RTYWEHYILPRRTAAIALLRRARDLGTVAADADLDVLVDMLAGAVTYRVL
MLBr_00815|M.leprae_Br4923 AAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLD
. : . :
MAV_4754|M.avium_104 S-GQRVDGKFVRRVIDTLILPAVRAAPE--
MSMEG_0465|M.smegmatis_MC2_155 R-GERVDANYVRKVIDTVIVPAVRATAY--
MAB_3151|M.abscessus_ATCC_1997 K-RTVIDETYMHRMVEEVILPLVQAPTTHT
Mflv_4384|M.gilvum_PYR-GCK TRGTAVDEVWLDRTARLITKGISA------
Mvan_1961|M.vanbaalenii_PYR-1 TRGANVDDAWIERTAHLITKGISS------
Mb1581|M.bovis_AF2122/97 IPNRPPTQDTVQALVDDVILPSLTRSTG--
Rv1556|M.tuberculosis_H37Rv IPNRPPTQDTVQALVDDVILPSLTRSTG--
MMAR_1695|M.marinum_M IPNRPPTPHTVQLLVDDFIMPGLTQATG--
MUL_1934|M.ulcerans_Agy99 IPNRPPTPHTVQLLVDDFIMPGLTQATG--
TH_4110|M.thermoresistible__bu Q-PEPPSARQLRCYLEVAYRQVGLLP----
MLBr_00815|M.leprae_Br4923 TNRPISKSDAVEGTVQFAWGGLSHVPLTRL
: