For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSGLRGRVVLVTGAGRGIGRSHCQRFAEEGADVIAVDVPAAAPDLAQTAAAVQQRGVRAATALADVSDFA ALAAAVDEAVGRLGRLDVLVGNAGIHPAAAPAWEITPQNWQQTLDVNLTGVWHTVKAGVPHMSRTARGGS IVIISSTSGIRGTPGAAPYSASKHAVVGLARTLANELGPQGIRVNTVHPGAVATAMVLNEATFRRLRPDL DNPTADDAAEALSARHLLPVPWVEPVDVSNAVVFLASDQARYITGTQIVVDAGLLAKA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_3019 | - | - | 100% (268) | carveol dehydrogenase |
| M. avium 104 | MAV_2983 | - | 2e-73 | 51.84% (272) | carveol dehydrogenase |
| M. avium 104 | MAV_0896 | - | 3e-73 | 50.72% (278) | carveol dehydrogenase ((+)-trans-carveol dehydrogenase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 7e-53 | 43.37% (279) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_1589 | - | 6e-71 | 49.82% (275) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2750 | - | 7e-53 | 43.37% (279) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-27 | 33.59% (259) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0073c | - | 2e-99 | 66.42% (268) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 6e-72 | 52.79% (269) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_4849 | - | 5e-74 | 51.96% (281) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_3237 | - | 5e-70 | 50.36% (274) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3392 | fabG | 1e-50 | 42.81% (278) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_2895 | - | 1e-98 | 67.16% (268) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2771|M.bovis_AF2122/97 ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS-
Rv2750|M.tuberculosis_H37Rv ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS-
MUL_3392|M.ulcerans_Agy99 MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIAS-
MAV_3019|M.avium_104 ----MSG-LRGRVVLVTGAGRGIGRSHCQRFAEEGADVIAVDVP------
Mvan_2895|M.vanbaalenii_PYR-1 ----MAG-LHGKVAVVTGAARGTGRAHCERLADAGADVIAIDIG------
MAB_0073c|M.abscessus_ATCC_199 ----MTR-LGGRVAVVTGAGKGMGRTHCERLAEEGSDVIAIDLP------
Mflv_1589|M.gilvum_PYR-GCK ----MGGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAIDVCGPISTH
TH_3237|M.thermoresistible__bu ----MAGRLEGKVAFITGAARGQGRAHAVRMAQEGADIIAVDICRQIDS-
MMAR_4754|M.marinum_M MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVEN
MSMEG_4849|M.smegmatis_MC2_155 ----MSGRVEGKVAFVTGAARGQGRSHALRLAQEGADIIAIDICGPIRPG
MLBr_01807|M.leprae_Br4923 -----MTDAAAKVSAAPGRGKPAFVSRSILVTG-GNRGIGLAVARR----
.:* .* .: ::. .: * *.: :
Mb2771|M.bovis_AF2122/97 --VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDE
Rv2750|M.tuberculosis_H37Rv --VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDE
MUL_3392|M.ulcerans_Agy99 --VPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQAGIDE
MAV_3019|M.avium_104 -------AAAPDLAQTAAAVQQRGVRAATALADVSDFAALAAAVDEAVGR
Mvan_2895|M.vanbaalenii_PYR-1 -------DLD-ELAATAESVTDRGRRCITGAADVRDFDGLAATVAASAAE
MAB_0073c|M.abscessus_ATCC_199 -------GSD-DLAQTAAAVEEHGRRCVWAFADVRDAAALTEAIDTGVRM
Mflv_1589|M.gilvum_PYR-GCK --TDIPPATPDDLAQTVDLVKGTGRRIVSEQVDVRDFAAVKAAVDSGVEQ
TH_3237|M.thermoresistible__bu --VQIPLASPEDLAETADLVKGLNRRIYTAEVDVRDFDALKAAVDTGVEQ
MMAR_4754|M.marinum_M --TTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVDAGVDE
MSMEG_4849|M.smegmatis_MC2_155 AETAIPASTSDDLAETANLVKGLDRRVVTAEVDVRDAAAIKAAVDSGVEQ
MLBr_01807|M.leprae_Br4923 ------LVADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEH
. . .. . ** * .: :.
Mb2771|M.bovis_AF2122/97 FGRLDIVVANAGIAMMQA-----GDDGWRDVIDVNLTGVFHTVQVAIPTL
Rv2750|M.tuberculosis_H37Rv FGRLDIVVANAGIAMMQA-----GDDGWRDVIDVNLTGVFHTVQVAIPTL
MUL_3392|M.ulcerans_Agy99 LGQVDIVVANAGIAPMQS-----GDDGWRDVIDVNLSGAYYTVEVAIPTM
MAV_3019|M.avium_104 LGRLDVLVGNAGIHPAAAPAWEITPQNWQQTLDVNLTGVWHTVKAGVPHM
Mvan_2895|M.vanbaalenii_PYR-1 LGGLDIVVANAGIHTAGAPTWKLSAQAWRDTLDVNLTGVWHTVKASVPHL
MAB_0073c|M.abscessus_ATCC_199 LGRLDIVVANAGVYDGLAPSCELTEDSWRRALDVNLTGAWHTVKAGAAHL
Mflv_1589|M.gilvum_PYR-GCK LGRLDIVVANAGIGNGGQTLDHTSEEDWNDMIDVNLSGVWKSVKAAVPHL
TH_3237|M.thermoresistible__bu LGRLDIIVANAGIGNGGETLDKTSEGDWTDMIDVNLAGVWKTVKAGVPHI
MMAR_4754|M.marinum_M LGRLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHL
MSMEG_4849|M.smegmatis_MC2_155 LGRLDIIVANAGIGNGGDTLDQTSEEDWDEMIDINLSGVWKSVKAGVPHI
MLBr_01807|M.leprae_Br4923 QGPVEVLVANAGIT-SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNM
* ::::*.***: : :*:**:*.: .: . :
Mb2771|M.bovis_AF2122/97 IEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLA
Rv2750|M.tuberculosis_H37Rv IEQGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLA
MUL_3392|M.ulcerans_Agy99 IEQGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLA
MAV_3019|M.avium_104 SRTARGGSIVIISSTSGIRGTPGAAP----YSASKHAVVGLARTLANELG
Mvan_2895|M.vanbaalenii_PYR-1 G--AAGGSIVIISSTNGIRGTANTAH----YTATKHAVVGLARTLANELG
MAB_0073c|M.abscessus_ATCC_199 LD---GGSVIIISSTNGLKGTANTAH----YTASKHAVVGLARTAANELG
Mflv_1589|M.gilvum_PYR-GCK LAGGNGGSIILTSSVGGLKPYPHTGH----YIAAKHGVIGLMRTFAVELG
TH_3237|M.thermoresistible__bu LAGGRGGSIILTSSVGGLKAYPHTGH----YVAAKHGVVGLMRTFAVELG
MMAR_4754|M.marinum_M IAGGNGGSIVLTSSVGGMKAYPHCGN----YVAAKHGVVGLMRSFAVELG
MSMEG_4849|M.smegmatis_MC2_155 VAGGRGGSIVLTSSVGGLKAYPHCGN----YVAAKHGVVGLMRGFAVELG
MLBr_01807|M.leprae_Br4923 IKQRFGRYIFMG-SVVGLSGVPGQAN----YAASKSGLIGMARSLARELG
* :.: *. *: * *:* .::*: * * *.
Mb2771|M.bovis_AF2122/97 PQNIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNLGNAL
Rv2750|M.tuberculosis_H37Rv PQNIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNLGNAL
MUL_3392|M.ulcerans_Agy99 PHSIRVNSLHPSGVDPPMINNEFIRHWLAD-----LVAETGSGPGAGNAL
MAV_3019|M.avium_104 PQGIRVNTVHPGAVATAMVLNEATFRRLRPDLDNPTADDAAEALSARHLL
Mvan_2895|M.vanbaalenii_PYR-1 PRSIRVNTVHPGAVATPTVRNEATYRRLCPDIENPTESDAARVLAARNLL
MAB_0073c|M.abscessus_ATCC_199 PQGIRVNTVHPGAVSTGMILNPAVIARLRPDLEHPTVEDAAEALAARTLL
Mflv_1589|M.gilvum_PYR-GCK QHSIRVNAVCPTNVNTPLFMNEGTMKLFRPDLENPGPDDLAVAAQFMHVL
TH_3237|M.thermoresistible__bu QHNIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPEDLKVVAQMMHTL
MMAR_4754|M.marinum_M QHMIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQLFHTL
MSMEG_4849|M.smegmatis_MC2_155 QHNIRVNTVHPTHVATPMLHNEGTFKMFRPDLENPGPDDMAPICQMFHTL
MLBr_01807|M.leprae_Br4923 SRSITANVVAPGFIDTEMTR----------------AMDSKYQEAALQAI
: * .* : * : . : :
Mb2771|M.bovis_AF2122/97 PVELVQPTD-IANAVAWLASEEARYVTGVTLPVDAGFVNKR
Rv2750|M.tuberculosis_H37Rv PVELVQPTD-IANAVAWLASEEARYVTGVTLPVDAGFVNKR
MUL_3392|M.ulcerans_Agy99 PVQILQADD-IAGALAWLVSDEARYITGVALPVDAGCVNKR
MAV_3019|M.avium_104 PVPWVEPVD-VSNAVVFLASDQARYITGTQIVVDAGLLAKA
Mvan_2895|M.vanbaalenii_PYR-1 PVPWVEPVD-VANAVCFLASDQARYITGTQLVVDAGLTQKA
MAB_0073c|M.abscessus_ATCC_199 PVPWVEAVD-ISNAVVFLASDEARYITGTQLVVDAGLTQKA
Mflv_1589|M.gilvum_PYR-GCK PVGWVEPRD-ISNAVLFLASDEARYVTGLPVTVDAGSMLK-
TH_3237|M.thermoresistible__bu PIGWVEPED-IANAVLFLASDEARYITGVTLPVDGGSCLK-
MMAR_4754|M.marinum_M PIPWVEAED-ISNAVLFLASDESRYITGVTLPVDAGGCLK-
MSMEG_4849|M.smegmatis_MC2_155 PIPWVEPID-ISNAVLFLASDEARYITGVTLPVDAGSCLK-
MLBr_01807|M.leprae_Br4923 PLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH
*: : . : ::.*: :*.*::: *::* : **.*