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VAGLHGKVAVVTGAARGTGRAHCERLADAGADVIAIDIGDLDELAATAESVTDRGRRCITGAADVRDFDG LAATVAASAAELGGLDIVVANAGIHTAGAPTWKLSAQAWRDTLDVNLTGVWHTVKASVPHLGAAGGSIVI ISSTNGIRGTANTAHYTATKHAVVGLARTLANELGPRSIRVNTVHPGAVATPTVRNEATYRRLCPDIENP TESDAARVLAARNLLPVPWVEPVDVANAVCFLASDQARYITGTQLVVDAGLTQKA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_2895 | - | - | 100% (265) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_5168 | - | 6e-69 | 50.92% (271) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4222 | - | 9e-68 | 50.74% (270) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2771 | - | 9e-56 | 47.12% (278) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_2430 | - | 2e-68 | 51.11% (270) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv2750 | - | 9e-56 | 47.12% (278) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-24 | 33.59% (256) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0073c | - | 9e-95 | 66.03% (262) | putative short chain dehydrogenase/reductase |
| M. marinum M | MMAR_4754 | - | 3e-70 | 51.30% (269) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_3019 | - | 1e-98 | 67.16% (268) | carveol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6031 | - | 3e-71 | 52.03% (271) | carveol dehydrogenase |
| M. thermoresistible (build 8) | TH_3237 | - | 2e-70 | 52.22% (270) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3392 | fabG | 1e-53 | 46.40% (278) | 3-ketoacyl-(acyl-carrier-protein) reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2771|M.bovis_AF2122/97 ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS-
Rv2750|M.tuberculosis_H37Rv ---MIDRPLEGKVAFITGAARGLGRAHAVRLAADGANIIAVDICEQIAS-
MUL_3392|M.ulcerans_Agy99 MSRPLDGPLSGRVAFITGAARGQGRAHALRLARDGADVIAVDLCDQIAS-
MAB_0073c|M.abscessus_ATCC_199 ----MTR-LGGRVAVVTGAGKGMGRTHCERLAEEGSDVIAIDLP------
MAV_3019|M.avium_104 ----MSG-LRGRVVLVTGAGRGIGRSHCQRFAEEGADVIAVDVP------
Mvan_2895|M.vanbaalenii_PYR-1 ----MAG-LHGKVAVVTGAARGTGRAHCERLADAGADVIAIDIG------
Mflv_2430|M.gilvum_PYR-GCK ----MAGRVEGKVAFITGAARGQGRAHAVRLAEEGADIIAVDICKQIDS-
TH_3237|M.thermoresistible__bu ----MAGRLEGKVAFITGAARGQGRAHAVRMAQEGADIIAVDICRQIDS-
MSMEG_6031|M.smegmatis_MC2_155 ----MAGRVEGKVAFITGAARGQGRSHAVRLAEEGADIIAVDVCRRISSN
MMAR_4754|M.marinum_M MTEQLGGRVAGKVAFITGAARGQGRSHAVRLAQEGADIIAVDVCKPIVEN
MLBr_01807|M.leprae_Br4923 -----MTDAAAKVSAAPGRGK-PAFVSRSILVTGGNRGIGLAVARR----
.:* .* .: . :. * *.: :
Mb2771|M.bovis_AF2122/97 VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDEFG
Rv2750|M.tuberculosis_H37Rv VPYPLSTADDLAATVELVEDAGGGIVARQGDVRDRASLSVALQAGLDEFG
MUL_3392|M.ulcerans_Agy99 VPYPLGTAEELATTVKLVEDTGARIVASQADVRDREALAAALQAGIDELG
MAB_0073c|M.abscessus_ATCC_199 -----GSD-DLAQTAAAVEEHGRRCVWAFADVRDAAALTEAIDTGVRMLG
MAV_3019|M.avium_104 -----AAAPDLAQTAAAVQQRGVRAATALADVSDFAALAAAVDEAVGRLG
Mvan_2895|M.vanbaalenii_PYR-1 -----DLD-ELAATAESVTDRGRRCITGAADVRDFDGLAATVAASAAELG
Mflv_2430|M.gilvum_PYR-GCK VLIPLSTPEDLAETADLVKNAGGRIHTAEVDVRDYDALKAAVDAGVEEFG
TH_3237|M.thermoresistible__bu VQIPLASPEDLAETADLVKGLNRRIYTAEVDVRDFDALKAAVDTGVEQLG
MSMEG_6031|M.smegmatis_MC2_155 EDIPASTPEDLAETVELVKGLNRRIVAEEVDVRDYDALKAVVDSGVEQLG
MMAR_4754|M.marinum_M TTIPASTPEDLAETADLVKGHNRRIFTAEADVRDYDALKAAVDAGVDELG
MLBr_01807|M.leprae_Br4923 ----LVADGHRVAVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQG
. . .. . ** * .: .. *
Mb2771|M.bovis_AF2122/97 RLDIVVANAGIAMMQA-----GDDGWRDVIDVNLTGVFHTVQVAIPTLIE
Rv2750|M.tuberculosis_H37Rv RLDIVVANAGIAMMQA-----GDDGWRDVIDVNLTGVFHTVQVAIPTLIE
MUL_3392|M.ulcerans_Agy99 QVDIVVANAGIAPMQS-----GDDGWRDVIDVNLSGAYYTVEVAIPTMIE
MAB_0073c|M.abscessus_ATCC_199 RLDIVVANAGVYDGLAPSCELTEDSWRRALDVNLTGAWHTVKAGAAHLLD
MAV_3019|M.avium_104 RLDVLVGNAGIHPAAAPAWEITPQNWQQTLDVNLTGVWHTVKAGVPHMSR
Mvan_2895|M.vanbaalenii_PYR-1 GLDIVVANAGIHTAGAPTWKLSAQAWRDTLDVNLTGVWHTVKASVPHLGA
Mflv_2430|M.gilvum_PYR-GCK RLDIIVANAGIGNGGQTLDKTDEPDWDDMIGVNLSGVWKTVKAGVPHILA
TH_3237|M.thermoresistible__bu RLDIIVANAGIGNGGETLDKTSEGDWTDMIDVNLAGVWKTVKAGVPHILA
MSMEG_6031|M.smegmatis_MC2_155 GLDIVVANAGIGNGGATLDKTSEADWDDMIGVNLSGVWKTVKAAVPHLIS
MMAR_4754|M.marinum_M RLDIIVANAGIGNGGATLDKTSEHDWQEMIDVNLSGVWKSVKAAVPHLIA
MLBr_01807|M.leprae_Br4923 PVEVLVANAGIT-SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIK
::::*.***: : :.***:*.: .: . :
Mb2771|M.bovis_AF2122/97 QGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLAPQ
Rv2750|M.tuberculosis_H37Rv QGTGGSIVLISSAAGLVGIGSSDPGSLGYAAAKHGVVGLMRAYANHLAPQ
MUL_3392|M.ulcerans_Agy99 QGRGGSIVLISSAAGLVGISSADAGAIGYVASKHALVGLMRVYANLLAPH
MAB_0073c|M.abscessus_ATCC_199 ---GGSVIIISSTNGLKGTANTAH----YTASKHAVVGLARTAANELGPQ
MAV_3019|M.avium_104 TARGGSIVIISSTSGIRGTPGAAP----YSASKHAVVGLARTLANELGPQ
Mvan_2895|M.vanbaalenii_PYR-1 A--GGSIVIISSTNGIRGTANTAH----YTATKHAVVGLARTLANELGPR
Mflv_2430|M.gilvum_PYR-GCK GGNGGSIILTSSVGGLKAYPHTGH----YVAAKHGVVGLMRTFAVELGAQ
TH_3237|M.thermoresistible__bu GGRGGSIILTSSVGGLKAYPHTGH----YVAAKHGVVGLMRTFAVELGQH
MSMEG_6031|M.smegmatis_MC2_155 GGNGGSIILTSSVGGLKAYPHTGH----YIAAKHGVVGLMRTFAVELGQH
MMAR_4754|M.marinum_M GGNGGSIVLTSSVGGMKAYPHCGN----YVAAKHGVVGLMRSFAVELGQH
MLBr_01807|M.leprae_Br4923 QRFGRYIFMG-SVVGLSGVPGQAN----YAASKSGLIGMARSLARELGSR
* :.: *. *: . * *:* .::*: * * *. :
Mb2771|M.bovis_AF2122/97 NIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNLGNALPV
Rv2750|M.tuberculosis_H37Rv NIRVNSVHPCGVDTPMINNEFFQQWLT-------TADMDAPHNLGNALPV
MUL_3392|M.ulcerans_Agy99 SIRVNSLHPSGVDPPMINNEFIRHWLAD-----LVAETGSGPGAGNALPV
MAB_0073c|M.abscessus_ATCC_199 GIRVNTVHPGAVSTGMILNPAVIARLRPDLEHPTVEDAAEALAARTLLPV
MAV_3019|M.avium_104 GIRVNTVHPGAVATAMVLNEATFRRLRPDLDNPTADDAAEALSARHLLPV
Mvan_2895|M.vanbaalenii_PYR-1 SIRVNTVHPGAVATPTVRNEATYRRLCPDIENPTESDAARVLAARNLLPV
Mflv_2430|M.gilvum_PYR-GCK NIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPDDMKVVGQLMHTLPI
TH_3237|M.thermoresistible__bu NIRVNSVHPTNVNTPLFMNEPTMKLFRPDLENPGPEDLKVVAQMMHTLPI
MSMEG_6031|M.smegmatis_MC2_155 SIRVNSVHPTNVNTPLFMNEGTMKLFRPDLENPGPDDMAVVAQMMHVLPV
MMAR_4754|M.marinum_M MIRVNSVHPTHVRTPMLHNEGTFKMFRPDLENPGPDDMAPICQLFHTLPI
MLBr_01807|M.leprae_Br4923 SITANVVAPGFIDTEMTR----------------AMDSKYQEAALQAIPL
* .* : * : . : :*:
Mb2771|M.bovis_AF2122/97 ELVQP-TDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
Rv2750|M.tuberculosis_H37Rv ELVQP-TDIANAVAWLASEEARYVTGVTLPVDAGFVNKR
MUL_3392|M.ulcerans_Agy99 QILQA-DDIAGALAWLVSDEARYITGVALPVDAGCVNKR
MAB_0073c|M.abscessus_ATCC_199 PWVEA-VDISNAVVFLASDEARYITGTQLVVDAGLTQKA
MAV_3019|M.avium_104 PWVEP-VDVSNAVVFLASDQARYITGTQIVVDAGLLAKA
Mvan_2895|M.vanbaalenii_PYR-1 PWVEP-VDVANAVCFLASDQARYITGTQLVVDAGLTQKA
Mflv_2430|M.gilvum_PYR-GCK GWVEP-EDIANAVLFLASDEARFITGVTLPVDGGSCLK-
TH_3237|M.thermoresistible__bu GWVEP-EDIANAVLFLASDEARYITGVTLPVDGGSCLK-
MSMEG_6031|M.smegmatis_MC2_155 GWVEP-RDISNAVLFLASDEARYVTGLPMTVDAGSMLK-
MMAR_4754|M.marinum_M PWVEA-EDISNAVLFLASDESRYITGVTLPVDAGGCLK-
MLBr_01807|M.leprae_Br4923 GRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH
: . :::.*: :*.*::: :::* : **.*