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MGCSSREEIVKVFDALDAALDRLGELSFDALTTRECLSLLQRCEMVRRRLPVPEHQLINHVARQASPAEL GGRLSHAIAEATLISRAEAARRVHTAADLGPRVGLTGEPLPPVLAATAARQREGLLGLEQVGACLIDCVS GWA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2972 | - | - | 100% (143) | REP13E12 repeat-containing protein |
| M. avium 104 | MAV_1426 | - | 9e-53 | 75.52% (143) | hypothetical protein MAV_1426 |
| M. avium 104 | MAV_2999 | - | 2e-49 | 71.63% (141) | hypothetical protein MAV_2999 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1728c | - | 8e-37 | 60.63% (127) | hypothetical protein Mb1728c |
| M. gilvum PYR-GCK | Mflv_3477 | - | 3e-14 | 36.64% (131) | hypothetical protein Mflv_3477 |
| M. tuberculosis H37Rv | Rv1702c | - | 8e-37 | 60.63% (127) | hypothetical protein Rv1702c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2374c | - | 4e-19 | 37.12% (132) | hypothetical protein MAB_2374c |
| M. marinum M | MMAR_1523 | - | 3e-34 | 55.73% (131) | hypothetical protein MMAR_1523 |
| M. smegmatis MC2 155 | MSMEG_6573 | - | 2e-15 | 40.68% (118) | hypothetical protein MSMEG_6573 |
| M. thermoresistible (build 8) | TH_3287 | - | 1e-07 | 29.69% (128) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2416 | - | 7e-33 | 56.00% (125) | hypothetical protein MUL_2416 |
| M. vanbaalenii PYR-1 | Mvan_3050 | - | 1e-24 | 46.97% (132) | hypothetical protein Mvan_3050 |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_1523|M.marinum_M ------MSSMSREEVVAAFDALDAVMARLQDLCFDGLTTPERLALLQRCE
MUL_2416|M.ulcerans_Agy99 ------MSSINWEEVVAAFDALDAVMTRLQDLCFDGLTTPERLALLQRCE
MAV_2972|M.avium_104 ------MGCSSREEIVKVFDALDAALDRLGELSFDALTTRECLSLLQRCE
Mb1728c|M.bovis_AF2122/97 ------MYSSSREEAVAAFDNLDTALNRVLKVSPDDLTIPECLAMLQRCE
Rv1702c|M.tuberculosis_H37Rv ------MYSSSREEAVAAFDNLDTALNRVLKVSPDDLTIPECLAMLQRCE
Mflv_3477|M.gilvum_PYR-GCK ----MYVRIMSGGDLQARIAALRAAFDDVAAAEIDLLTRAELVAALDDLE
MSMEG_6573|M.smegmatis_MC2_155 ---------MDDG-VQDAVAALDAALNTLLTLPHSALTDAELLTICAGLQ
Mvan_3050|M.vanbaalenii_PYR-1 -------MGCSREDVLGAFDALDAVVESILALDYDALSAAERVRLEARLE
MAB_2374c|M.abscessus_ATCC_199 ------MSSIADSDAAEVLAGLCGAVDALSELDTSALTRHDRLTILRDVE
TH_3287|M.thermoresistible__bu MGQQFVTAGAARARVGELLAAVDAAYAEMRALCLDEVGTGFRLELAERLE
. : . : . : : :
MMAR_1523|M.marinum_M VARRRLPSIEHPLINQLVEQAGEQELGG-KLAAVLAGRLRVSRGEASRRL
MUL_2416|M.ulcerans_Agy99 VARRRLPSIEHPLINQLGEQAGEQELGG-KLAAVLAGRLRVSRGEASRRL
MAV_2972|M.avium_104 MVRRRLPVPEHQLINHVARQASPAELGG-RLSHAIAEATLISRAEAARRV
Mb1728c|M.bovis_AF2122/97 KIRRRLPAAEHPFINKLADQTDQTELGG-KLPFALAERLHISRGEASRRI
Rv1702c|M.tuberculosis_H37Rv KIRRRLPAAEHPFINKLADQTDQTELGG-KLPFALAERLHISRGEASRRI
Mflv_3477|M.gilvum_PYR-GCK ELSCQLPAVGHRLLARLQVEATPQQLGAKSWSEVLRVRWRISTTEANRRL
MSMEG_6573|M.smegmatis_MC2_155 DARNRIPAVEHRAIAALSQQTTPAAIGAKSWPLVLATRLGISSKEARRRC
Mvan_3050|M.vanbaalenii_PYR-1 RNLRRIPTVEHELLASVIAETEPARLGEGSWKKVLTTALRISGAEAGRRL
MAB_2374c|M.abscessus_ATCC_199 TLLRRIPTATHGIVNELVAGHVPGQFGGASLGDVLADTLRITRADARRRI
TH_3287|M.thermoresistible__bu TQCRINRGLMYRVFAQLADPPDEPAMVP-AVRDRLWARLRITPGEVKRRL
: . : : : :: :. **
MMAR_1523|M.marinum_M REAADLGPRRALTGEQLAPLLSATASAVRQGRIGAGHVRVIREFCGQVPA
MUL_2416|M.ulcerans_Agy99 GEAADLGPRRALTGEQLAPLLSATASAVRQGRIGAGHVRVIREFCGQVPA
MAV_2972|M.avium_104 HTAADLGPRVGLTGEPLPPVLAATAARQREGLLG----------------
Mb1728c|M.bovis_AF2122/97 HEAADLGPRRTLTGQPLPPLLTATAAAQRAGHLGPAHVQVIRCFLHQLPH
Rv1702c|M.tuberculosis_H37Rv HEAADLGPRRTLTGQPLPPLLTATAAAQRAGHLGPAHVQVIRCFLHQLPH
Mflv_3477|M.gilvum_PYR-GCK TEAGLLAPRPSLTGPALPPQLAATAIAQARGLINAEHVAVIRKAVKKLPG
MSMEG_6573|M.smegmatis_MC2_155 TDAAELGPRVSMTGEALAPKREHIAAAQADGTLTPDHVAELFKFFTKCPD
Mvan_3050|M.vanbaalenii_PYR-1 KRAKTLGPRRGLTGTPLPPLWESTAAAQAQGLLSEEHVAVIAAFHKRLPA
MAB_2374c|M.abscessus_ATCC_199 RDAAELAPTVALTGTSIEPVLAATSAAQRAGTAGGDHIAVIRRFWDRVPR
TH_3287|M.thermoresistible__bu RVAALLRPRRRLSGPPLPPVLARVAGAVESGLLGEEHLRVITTVMAALPS
* * * ::* : * : *
MMAR_1523|M.marinum_M EVDLETRERAEAHLARLAGQFRPDQLAKLAQRLMDCVNPDGRY-SDEDRA
MUL_2416|M.ulcerans_Agy99 EVDLETRERAEAHLARLAGQFRPDQLAKLAQRLMDCVNPDGRY-SDEDRA
MAV_2972|M.avium_104 -------------------------LEQVGACLIDCVS------------
Mb1728c|M.bovis_AF2122/97 HVDLPTREKAEAELATLGGRFRPDQLHKLATKLADCLNPDGNY-NDTDRA
Rv1702c|M.tuberculosis_H37Rv HVDLPTREKAEAELATLGGRFRPDQLHKLATKLADCLNPDGNY-NDTDRA
Mflv_3477|M.gilvum_PYR-GCK WVDVATREQFEVNLVRTAVGNGPKELRDAAELTLFLLDQDGPEPDDTERA
MSMEG_6573|M.smegmatis_MC2_155 WVTYAEQCRLEEKLVTGAIGADPETVRQAVDHAVFLLDQDGPAPTDNPPT
Mvan_3050|M.vanbaalenii_PYR-1 WVDIETRAEADRQLAHAGSGLDPEGLDEAAGVLLAMINPDGAQPCDKERA
MAB_2374c|M.abscessus_ATCC_199 TVDVQTRMTAERQLARLTQTLRPDELGKAAQRLLAHLDPDGSLTSDTDRA
TH_3287|M.thermoresistible__bu AVSVTDREAVEASLIAEAARSDAGIVRQVGRRIEEIFNPDGHY-DDQDRA
: . ..
MMAR_1523|M.marinum_M RRRGLTLGRQGRDGMSRISGWLTPEARAGLDAVLAKLAAPGMCNPDD--E
MUL_2416|M.ulcerans_Agy99 RRRGLTLGRQGRDGMSRISGWLTPEARAGLDAVLAKLAAPGMCNPDD--E
MAV_2972|M.avium_104 -------------------GWA----------------------------
Mb1728c|M.bovis_AF2122/97 RRRSIILGNQGPDGMSAISGYLTPEARATVDAVLAKLAAPGMANPAD--D
Rv1702c|M.tuberculosis_H37Rv RRRSIILGNQGPDGMSAISGYLTPEARATVDAVLAKLAAPGMANPAD--D
Mflv_3477|M.gilvum_PYR-GCK RKRGLTKGKQRPDGMIDLAGTLTPEAWAVLEVIFAKYAAPGMCNPAD--P
MSMEG_6573|M.smegmatis_MC2_155 KPFGITFGPQQPDGSYHLRGKVSAEFKATFDPIDEKLAAPGMCNPTD--Q
Mvan_3050|M.vanbaalenii_PYR-1 RKRGIRISKQHPDGTATISGTLTPEALAIWQAIFAKEAAPGANNPESEHT
MAB_2374c|M.abscessus_ATCC_199 RRRGFRMGRQGADLMTAGAFDLDPELRSYLDAIFAKYAAPGVCHPDD--E
TH_3287|M.thermoresistible__bu RRRGIHLGDQQRDGMSAISGWIDPQLRAYLEAVTAAVR-PGRHLPHTTTD
MMAR_1523|M.marinum_M SPVVQA------------------------------PAGADAVSRDRRSV
MUL_2416|M.ulcerans_Agy99 SPVVQA------------------------------PAGADAVSRDRRSV
MAV_2972|M.avium_104 --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 TPCLAG------------------------------TPSQAAIEADTRSA
Rv1702c|M.tuberculosis_H37Rv TPCLAG------------------------------TPSQAAIEADTRSA
Mflv_3477|M.gilvum_PYR-GCK EPCTAG------------------------------TPTQAQIDNDQRSL
MSMEG_6573|M.smegmatis_MC2_155 TPCISG------------------------------TPSQQQIDSDQRGA
Mvan_3050|M.vanbaalenii_PYR-1 EDSTSGGAADDASDAPGDHAGAASSAASGASDAAEHDPQPERCGSDTRTQ
MAB_2374c|M.abscessus_ATCC_199 NPCVDG------------------------------DPDSDAARHDVRSV
TH_3287|M.thermoresistible__bu TTGTTG------TTETTGTAGTAGTAATAADTAADGVGDIDTGGVDLRSA
MMAR_1523|M.marinum_M GQRHHDGLNAAVRALLASGDLGQHNGLPASIIVTTTLGELQRAC------
MUL_2416|M.ulcerans_Agy99 GQRHHDGLNAAVRALLASGDLGQHNGLPASIIVTTTRGELQRAC------
MAV_2972|M.avium_104 --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 GQRHHDGLLAALRALLCSGELGQHNGLPAAIIVSTSLTELQSRA------
Rv1702c|M.tuberculosis_H37Rv GQRHHDGLLAALRALLCSGELGQHNGLPAAIIVSTSLTELQSRA------
Mflv_3477|M.gilvum_PYR-GCK AQRQHDALVAVGRIALMSGELGQLNGLPVSIIIRTTLQDLESRA------
MSMEG_6573|M.smegmatis_MC2_155 PERRHDAMLTAMRLLLAHKDLGQINGLPATLLVTTTLQELEKAA------
Mvan_3050|M.vanbaalenii_PYR-1 AQRNHDAFLAVGRRLLESGELGTHNGLPVTVIVSTTLQELEKGA------
MAB_2374c|M.abscessus_ATCC_199 AQRQHDALKAVCRSILCSGELGHHRGLPVTTIVTTTLRELESGA------
TH_3287|M.thermoresistible__bu AQRRHDGLTLGLKIAVASGRLGSHRGHPVTVIVRTTLGELNQAAHAVADP
MMAR_1523|M.marinum_M -----GRGLTGGGTVLPISDVIRLARHAHHYLAVFDRGKAVGLYH--AKR
MUL_2416|M.ulcerans_Agy99 -----GRGLTGGGTVLPISDVIRLARHAHHYLAVFDRGKAVGLYH--AKR
MAV_2972|M.avium_104 --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 -----GHALTGGGTLLPMSDVIRLASHANHYLRIFDHGRELALYH--TKR
Rv1702c|M.tuberculosis_H37Rv -----GHALTGGGTLLPMSDVIRLASHANHYLRIFDHGRELALYH--TKR
Mflv_3477|M.gilvum_PYR-GCK -----GVGTTGGGTVVPIKDVIRMGGHANHYLAVFDRATGSALDLFRTRR
MSMEG_6573|M.smegmatis_MC2_155 -----GVAITAGGTKLSIPDLIRLASQALHYLAVYDEHTGIPLYLGRARR
Mvan_3050|M.vanbaalenii_PYR-1 -----GVAVTGGGSLLPMPDLIRLAARAHHYLYVYDQHSGKSLYLGRAKR
MAB_2374c|M.abscessus_ATCC_199 -----GHAATGGGSLLPMPDPIRMASHAHHYLAVFDDD-GRALYLGRAKR
TH_3287|M.thermoresistible__bu RVSMPGPARTGGTGVLPMRELIRMAADAIHYLAVFDDHTERPLYLGRQKR
MMAR_1523|M.marinum_M LATAGQRLVLYAK---------------DRGCTRPGCDVPGYQC-EVHHV
MUL_2416|M.ulcerans_Agy99 LATAGHAWCCMPKTVVAPVRAVMCRAINARCIMSPRGPPAGAPT-SIN--
MAV_2972|M.avium_104 --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 LASPGQRIVLYAK---------------DRGCSFPNCDVPGYLT-EVHHV
Rv1702c|M.tuberculosis_H37Rv LASPGQRIVLYAK---------------DRGCSFPNCDVPGYLT-EVHHV
Mflv_3477|M.gilvum_PYR-GCK VASPAQRVMLIAR---------------DGGCTKPCCTVGAYGCQVHHAE
MSMEG_6573|M.smegmatis_MC2_155 TASAGQRLAIWAR---------------DRGCTRPGCTANGYRCQAHHAT
Mvan_3050|M.vanbaalenii_PYR-1 LANAAQRIVLHAR---------------DRGCTRPGCTAPGYWCQAHHAS
MAB_2374c|M.abscessus_ATCC_199 IATADQRIVLTAK---------------ERGCTYPGCDRPAYHCQAHHMD
TH_3287|M.thermoresistible__bu IATADQRLICYAR---------------DGGCTAPGCGEPGYHAETHHQP
MMAR_1523|M.marinum_M AAWATSGRTDIDQLTLACGPDHKLLEQG---WRTRKNAHGDTEWLP----
MUL_2416|M.ulcerans_Agy99 SLWPAGLTTNCSSRVGALARTPTVIPNG---CHRRTSTMDSQEPTPTTTP
MAV_2972|M.avium_104 --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 TDFAQCQETDINELTQGCGPHHQLATTGG--WITRKRKDGTTEWLP----
Rv1702c|M.tuberculosis_H37Rv TDFAQCQETDINELTQGCGPHHQLATTGG--WITRKRKDGTTEWLP----
Mflv_3477|M.gilvum_PYR-GCK TDYAHGGNTNIDELGLACGPDNRSVTEGG--WTTRMNDRCEVEWIP----
MSMEG_6573|M.smegmatis_MC2_155 TDYAKGGLTDADALALACGCDNRLVGEAPNKWTTRINNHGQCEWIP----
Mvan_3050|M.vanbaalenii_PYR-1 ADFVDGGLTNIDDLTLACPCDHRMLDNTG--WRTRKNGKNQTEWLP----
MAB_2374c|M.abscessus_ATCC_199 -EWAAGGNTDIASLTLGCERHHKLLGTDHQCWQTIRGPDGRTWWIP----
TH_3287|M.thermoresistible__bu -AWEDGGLTDADHLFFACGPHHSGLTEGR--WQATITPTGRLAWTN----
MMAR_1523|M.marinum_M --------PPHLD-HGQPRTNTYHHP-------EKLLRDSAAD-------
MUL_2416|M.ulcerans_Agy99 KNCSATAQPTKAK-RGVDRAVVWHAEPMAGKEIDRVRATSALA-------
MAV_2972|M.avium_104 --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 --------PAHLD-HGQPRTNSYFHP-------EKLLHDSDED-------
Rv1702c|M.tuberculosis_H37Rv --------PAHLD-HGQPRTNSYFHP-------EKLLHDSDED-------
Mflv_3477|M.gilvum_PYR-GCK --------PPGLD-TGQARVNTYHRP-------ERLLAPP----------
MSMEG_6573|M.smegmatis_MC2_155 --------PDLLD-RGQHRTNTYHHP-------ETLLADINRDQKTDGDN
Mvan_3050|M.vanbaalenii_PYR-1 --------PPDLD-TGQHRVNGHHHP-------ERYLLPE----------
MAB_2374c|M.abscessus_ATCC_199 --------PAHVDPYRTPRSNWFHHP-------DGYLRE-----------
TH_3287|M.thermoresistible__bu -------------DHHPPTVNHAHHP-------EELLRAHTDP-------
MMAR_1523|M.marinum_M ---------------------EGEEGG-----------------------
MUL_2416|M.ulcerans_Agy99 ---------------------VIKQHPAMVLFVLSPALALLAVIWWLAGA
MAV_2972|M.avium_104 --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 ---------------------DP---------------------------
Rv1702c|M.tuberculosis_H37Rv ---------------------DP---------------------------
Mflv_3477|M.gilvum_PYR-GCK ---------------------EDPEPP------DQTRSTATEPAAVQAID
MSMEG_6573|M.smegmatis_MC2_155 REQHHTDTGADTGTVHVNGHGEKPAIPPELLDQGQQRTAPYHQAEVPPVN
Mvan_3050|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2374c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3287|M.thermoresistible__bu --------------------------------------------------
MMAR_1523|M.marinum_M -------------------------------------------
MUL_2416|M.ulcerans_Agy99 GWAIAAALAVLVVGVAVVVRKR---------------------
MAV_2972|M.avium_104 -------------------------------------------
Mb1728c|M.bovis_AF2122/97 -------------------------------------------
Rv1702c|M.tuberculosis_H37Rv -------------------------------------------
Mflv_3477|M.gilvum_PYR-GCK DPEAQAPRPADDPGEPGGPAP---------PEGEAA-------
MSMEG_6573|M.smegmatis_MC2_155 TRDTRSSTTTRDANRHNGNGDRNSAENRNGPSKNAAGDDDEPR
Mvan_3050|M.vanbaalenii_PYR-1 -----DDLPEDDQGP----------------------------
MAB_2374c|M.abscessus_ATCC_199 -------------------------------------------
TH_3287|M.thermoresistible__bu ---------PEDPG-----------------------------