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MYVRIMSGGDLQARIAALRAAFDDVAAAEIDLLTRAELVAALDDLEELSCQLPAVGHRLLARLQVEATPQ QLGAKSWSEVLRVRWRISTTEANRRLTEAGLLAPRPSLTGPALPPQLAATAIAQARGLINAEHVAVIRKA VKKLPGWVDVATREQFEVNLVRTAVGNGPKELRDAAELTLFLLDQDGPEPDDTERARKRGLTKGKQRPDG MIDLAGTLTPEAWAVLEVIFAKYAAPGMCNPADPEPCTAGTPTQAQIDNDQRSLAQRQHDALVAVGRIAL MSGELGQLNGLPVSIIIRTTLQDLESRAGVGTTGGGTVVPIKDVIRMGGHANHYLAVFDRATGSALDLFR TRRVASPAQRVMLIARDGGCTKPCCTVGAYGCQVHHAETDYAHGGNTNIDELGLACGPDNRSVTEGGWTT RMNDRCEVEWIPPPGLDTGQARVNTYHRPERLLAPPEDPEPPDQTRSTATEPAAVQAIDDPEAQAPRPAD DPGEPGGPAPPEGEAA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_3477 | - | - | 100% (506) | hypothetical protein Mflv_3477 |
| M. gilvum PYR-GCK | Mflv_4397 | - | 0.0 | 91.02% (501) | hypothetical protein Mflv_4397 |
| M. gilvum PYR-GCK | Mflv_1835 | - | 0.0 | 83.99% (506) | hypothetical protein Mflv_1835 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1159c | - | 1e-113 | 49.67% (451) | hypothetical protein Mb1159c |
| M. tuberculosis H37Rv | Rv1128c | - | 1e-113 | 49.67% (451) | hypothetical protein Rv1128c |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0990c | - | 2e-94 | 46.21% (422) | hypothetical protein MAB_0990c |
| M. marinum M | MMAR_3121 | - | 1e-103 | 45.54% (448) | hypothetical protein MMAR_3121 |
| M. avium 104 | MAV_2999 | - | 1e-114 | 49.23% (453) | hypothetical protein MAV_2999 |
| M. smegmatis MC2 155 | MSMEG_2663 | - | 1e-115 | 45.49% (510) | hypothetical protein MSMEG_2663 |
| M. thermoresistible (build 8) | TH_3287 | - | 1e-60 | 35.06% (502) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2371 | - | 1e-103 | 45.09% (448) | hypothetical protein MUL_2371 |
| M. vanbaalenii PYR-1 | Mvan_4912 | - | 0.0 | 76.18% (508) | hypothetical protein Mvan_4912 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3477|M.gilvum_PYR-GCK ----MYVRIMSGGDLQARIAALRAAFDDVAAAEIDLLTRAELVAALDDLE
Mvan_4912|M.vanbaalenii_PYR-1 ----MYVRAMSGSDVQAAVTALRTAFDDMAACDVDLLTRPDLVAALDELE
MSMEG_2663|M.smegmatis_MC2_155 -MIRTSVRYMA-AEVGTALAALHAAMRDVLALPYTALSDADLLDVCAGIQ
Mb1159c|M.bovis_AF2122/97 -------MCSTREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCE
Rv1128c|M.tuberculosis_H37Rv -------MCSTREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCE
MAV_2999|M.avium_104 ----MRGMSSDREAVSAAFDAIDAALDDLLDCDYAALATREKLALLNRCE
MMAR_3121|M.marinum_M ---MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLE
MUL_2371|M.ulcerans_Agy99 ---MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLE
MAB_0990c|M.abscessus_ATCC_199 ---------------MSSIGVVEAAVDAFCAESIEDLTAGEALAMLARLK
TH_3287|M.thermoresistible__bu MGQQFVTAGAARARVGELLAAVDAAYAEMRALCLDEVGTGFRLELAERLE
. : * . : : :
Mflv_3477|M.gilvum_PYR-GCK ELSCQLPAVGHRLLARLQVEATPQQLGAKSWSEVLRVRWRISTTEANRRL
Mvan_4912|M.vanbaalenii_PYR-1 TLGCRLPSVSHRLLARLQAEATPPQMGAKSWKEVLAVRWRISTSEAHRRL
MSMEG_2663|M.smegmatis_MC2_155 DVRNLAPAVEHRAIAALSEQTTPAAIGAKSWPLVLATRLGISSKEARRRC
Mb1159c|M.bovis_AF2122/97 TARRQLPSVEHTLINQIGEQSTEEELGGK-LGLTLADRLRITRSEAKRRV
Rv1128c|M.tuberculosis_H37Rv TARRQLPSVEHTLINQIGEQSTEEELGGK-LGLTLADRLRITRSEAKRRV
MAV_2999|M.avium_104 RLRRRLPAIEHPLINALARDATPAELGGR-LSHAIAEATLISRAEAARRV
MMAR_3121|M.marinum_M VVARRLPVAQYALLNQLDEQAGEAELGGR-LAAVVASRLRITRSEAGRRV
MUL_2371|M.ulcerans_Agy99 VVARRLPAAQYALVNQLDEQPGEAELGGR-LAAVVASRLRITRSEAGRRV
MAB_0990c|M.abscessus_ATCC_199 VVQRRLASRGLGLVSAVTGQASPMQLGGTSYAEVLSRRMHMGKRAARRRI
TH_3287|M.thermoresistible__bu TQCRINRGLMYRVFAQLADPPDEPAMVPA-VRDRLWARLRITPGEVKRRL
. : . : : : . **
Mflv_3477|M.gilvum_PYR-GCK TEAGLLAPRPSLTGPALPPQLAATAIAQARGLINAEHVAVIRKAVKKLPG
Mvan_4912|M.vanbaalenii_PYR-1 TEAAVLAPRQAMTGESLPPALPATATAQAHGLINAEHVEVIRKAMAKLPG
MSMEG_2663|M.smegmatis_MC2_155 ADAAELGPRVSLTGEALAPKREHIAAAQADGALTPDHVTELFKFFTKCPD
Mb1159c|M.bovis_AF2122/97 AEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPS
Rv1128c|M.tuberculosis_H37Rv AEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPS
MAV_2999|M.avium_104 HTAADLGPRVGLTGEPLPPLLAATAAAQREGSLGLEQVAVIRKFCHQLPG
MMAR_3121|M.marinum_M AEAADVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRRLPA
MUL_2371|M.ulcerans_Agy99 AEAAEVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRQLPA
MAB_0990c|M.abscessus_ATCC_199 ADAELLAPRRAITGEQLAPQLPHTAQALGRGDIGEEHLRIIRHFFDRLPV
TH_3287|M.thermoresistible__bu RVAALLRPRRRLSGPPLPPVLARVAGAVESGLLGEEHLRVITTVMAALPS
* : * ::* : * * * * : :: : *
Mflv_3477|M.gilvum_PYR-GCK WVDVATREQFEVNLVRTAVGNGPKELRDAAELTLFLLDQDGPEPDDTERA
Mvan_4912|M.vanbaalenii_PYR-1 FVDTATRERIEVDLVRTAVGNGPKELKDSADRTLFLLDQDGPEPDERERA
MSMEG_2663|M.smegmatis_MC2_155 WVTYAEQCRLEEKLVTGAIGADPETVRQAVDHAVFLLDQDGPAPTDNPPT
Mb1159c|M.bovis_AF2122/97 WVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDGDYTDE-DRA
Rv1128c|M.tuberculosis_H37Rv WVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDGDYTDE-DRA
MAV_2999|M.avium_104 WIDQATRERAEADLANQGTRYRPEQLAALAGTLADCLNPDGLYRDE-DRA
MMAR_3121|M.marinum_M GVDVGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPDGRHSDE-DRA
MUL_2371|M.ulcerans_Agy99 GVDVGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPDGRHSDE-DRA
MAB_0990c|M.abscessus_ATCC_199 VVDAATREAAEAQLAVMATQFRPEALRVGADRMMALLNPDGQFSDA-DRA
TH_3287|M.thermoresistible__bu AVSVTDREAVEASLIAEAARSDAGIVRQVGRRIEEIFNPDGHYDDQ-DRA
: * * . . : :: ** :
Mflv_3477|M.gilvum_PYR-GCK RKRGLTKGKQRPDGMIDLAGTLTPEAWAVLEVIFAKYAAP----------
Mvan_4912|M.vanbaalenii_PYR-1 RKRAVTKHKQREDGMVDVSATLTPEAWAVWEAIFAKFAAP----------
MSMEG_2663|M.smegmatis_MC2_155 KPFGITFGPQQPDGSYHLRGKVSAEFKATFDPIDEKLAAP----------
Mb1159c|M.bovis_AF2122/97 RRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAP----------
Rv1128c|M.tuberculosis_H37Rv RRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAP----------
MAV_2999|M.avium_104 RRRSLTLGNQHADGMSELRGLLTPELRATLEAVLAKLAAP----------
MMAR_3121|M.marinum_M RRRGLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAP----------
MUL_2371|M.ulcerans_Agy99 RRRGLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAP----------
MAB_0990c|M.abscessus_ATCC_199 RRRGITIGPQGFDGMSAISGLLDPETRAYLDAVFAKLAAP----------
TH_3287|M.thermoresistible__bu RRRGIHLGDQQRDGMSAISGWIDPQLRAYLEAVTAAVRPGRHLPHTTTDT
: .: * ** : . : .: * : : .
Mflv_3477|M.gilvum_PYR-GCK ----------GMCNPADPEPCTAGTPTQAQIDNDQ-----RSLAQRQHDA
Mvan_4912|M.vanbaalenii_PYR-1 ----------GMCNPDDPEPCTSGTPSQAQIDHDQ-----RSLAQRQHDA
MSMEG_2663|M.smegmatis_MC2_155 ----------GMCNPTDQTPCISGTPSQQQIDHDE-----RGAPERRHDA
Mb1159c|M.bovis_AF2122/97 ----------GMCNPEQKAPCVNGAPSKEQARRDT-----RSCPQRNHDA
Rv1128c|M.tuberculosis_H37Rv ----------GMCNPEQKAPCVNGAPSKEQARRDT-----RSCPQRNHDA
MAV_2999|M.avium_104 ----------GMCNPLDESPCVDGTPTEQAIEGDT-----RSAAQRNHDG
MMAR_3121|M.marinum_M ----------GMCNPEDEAAVVDGPVSPDAADRDS-----RSVGQRQHDG
MUL_2371|M.ulcerans_Agy99 ----------GMCNPEDEAAVVDGPVSRDAADRDS-----RSVSQRQHDG
MAB_0990c|M.abscessus_ATCC_199 ----------GMCNPNDQSPLVDGQPADDAAERDT-----RTVAQRHHDA
TH_3287|M.thermoresistible__bu TGTTGTTETTGTAGTAGTAATAADTAADGVGDIDTGGVDLRSAAQRRHDG
* ... . . : * * :*.**.
Mflv_3477|M.gilvum_PYR-GCK LVAVGRIALMSGELGQLNGLPVSIIIRTTLQDLESRA-----------GV
Mvan_4912|M.vanbaalenii_PYR-1 LLAGGRIALMSGELGKLNGLPVSVIIRTTLQDLESRA-----------GV
MSMEG_2663|M.smegmatis_MC2_155 MLTAMRLLLAHKDLGQINGLPATLLITTTLQELEKAA-----------GV
Mb1159c|M.bovis_AF2122/97 LNAGLRSLLTSGNLGQHNGLPASIIVTTTLKDLEAAA-----------GA
Rv1128c|M.tuberculosis_H37Rv LNAELRSLLTSGNLGQHNGLPASIIVTTTLKDLEAAA-----------GA
MAV_2999|M.avium_104 LLAGLRALLASGNLGQHNGLPASIIVTTTLADLETAA-----------GK
MMAR_3121|M.marinum_M FNAALRAVLASGELGQHNGLPASIIVSTTLKELEAAA-----------GR
MUL_2371|M.ulcerans_Agy99 FNAALRAVLASGELGQHNGLPASIIVSTTLKELEAAA-----------GR
MAB_0990c|M.abscessus_ATCC_199 LRAALRSTLVSTELGSHHGLPVTVVVTTTLKELEDAA-----------GI
TH_3287|M.thermoresistible__bu LTLGLKIAVASGRLGSHRGHPVTVIVRTTLGELNQAAHAVADPRVSMPGP
: : : **. .* *.:::: *** :*: * *
Mflv_3477|M.gilvum_PYR-GCK GTTGGGTVVPIKDVIRMGGHANHYLAVFDRATGSALDLFRTRRVASPAQR
Mvan_4912|M.vanbaalenii_PYR-1 GVTGGGTVMPIAEVIRMAGHANHYLAVFDRATGSALDLFRTKRVASAAQR
MSMEG_2663|M.smegmatis_MC2_155 AITAGGTKLSIPDLIRLASQALHYLAVYDEHTGVPLYLGRARRTASAGQR
Mb1159c|M.bovis_AF2122/97 GLTGGGTILPISDVIRLARHANHYLAIFDR--GKALALYHTKRLASPAQR
Rv1128c|M.tuberculosis_H37Rv GLTGGGTILPISDVIRLARHANHYLAIFDR--GKALALYHTKRLASPAQR
MAV_2999|M.avium_104 GLTGGGTLLPMSDVIRLSRHAHHYLAIFDK--GKALALYHTKRLASPGQR
MMAR_3121|M.marinum_M GLTGGGTLLPMSDVIRLARHAHHYLAVFDR--GEAIGLYHAKRLATPGQR
MUL_2371|M.ulcerans_Agy99 GLTGGGTLLPMSDVIRLARHAHHYLAVFDR--GEAIGLYHAKRLATPGQR
MAB_0990c|M.abscessus_ATCC_199 AITGAGTRLPMRDLIRMATHAHHYLAIFDDH-GRALYLGRSQRIASPDQR
TH_3287|M.thermoresistible__bu ARTGGTGVLPMRELIRMAADAIHYLAVFDDHTERPLYLGRQKRIATADQR
. *.. :.: ::**:. .* ****::* .: * : :* *:. **
Mflv_3477|M.gilvum_PYR-GCK VMLIARDGGCTKPCCTVGAYGCQVHHAETDYAHGGNTNIDELGLACGPDN
Mvan_4912|M.vanbaalenii_PYR-1 IMLIARDGGCTKPGCTVGAYGCQGHHVEADFAKGGNTNVDELGLACGPDN
MSMEG_2663|M.smegmatis_MC2_155 LAIWARDRGCTRPGCTANGYRCQAHHATTDYAKGGLTDADALALACGCDN
Mb1159c|M.bovis_AF2122/97 IMLYAKDSGCSAPGCDVPGYYCEVHHVT-PYAQCRNTDVNDLTLGCGGHH
Rv1128c|M.tuberculosis_H37Rv IMLYAKDSGCSAPGCDVPGYYCEVHHVT-PYAQCRNTDVNDLTLGCGGHH
MAV_2999|M.avium_104 IVLYAKDRGCTAPGCTVPGYYAEVHHCT-DYATCHTTDINDLTFACGPHH
MMAR_3121|M.marinum_M IVLYAKDRGCTRPGCDVAGYQCEVHHVA-AWAISGRTDINQLTLACGPDH
MUL_2371|M.ulcerans_Agy99 IVLYAKDRGCTRPGCDVAGYQCEVHHVA-AWAISGRTDINQLTLACGPDH
MAB_0990c|M.abscessus_ATCC_199 LVLHARDRGCTHPDCHVPGYLCQAHHIT-EWVHDGPTDIDNLTFACAPHH
TH_3287|M.thermoresistible__bu LICYARDGGCTAPGCGEPGYHAETHHQP-AWEDGGLTDADHLFFACGPHH
: *:* **: * * .* .: ** : *: : * :.*. .:
Mflv_3477|M.gilvum_PYR-GCK RSVT--EGGWTTRMNDRCEVEWIPPPGLDT-GQARVNTYHRPERLLAPPE
Mvan_4912|M.vanbaalenii_PYR-1 RSVDN-NGGWTTQMNERCEVEWIPPPPLDT-GQARINNYHRPERLLRPPE
MSMEG_2663|M.smegmatis_MC2_155 RLVGEAPNKWTTRINNHGQCEWIPPQLLDR-GQHRTNTYHHPETLLADIK
Mb1159c|M.bovis_AF2122/97 PLAERG---WTTRKNAHGDTEWLPPPHLDH-GQPRVNTFHHPEKLL----
Rv1128c|M.tuberculosis_H37Rv PLAERG---WTTRKNAHGDTEWLPPPHLDH-GQPRVNTFHHPEKLL----
MAV_2999|M.avium_104 RLLQPGA--WTTHKNARGETQWLPPPHLDR-NQPRTNTFHHPEKLLRGED
MMAR_3121|M.marinum_M KLLEQG---WRTRKNAHGDTEWLPPPHLDH-GQPRTNTYHHPEKLLR---
MUL_2371|M.ulcerans_Agy99 KLLEQG---WRTRKNAHGDTEWLPPPHLDH-GQPRTNSYHHPEKLLR---
MAB_0990c|M.abscessus_ATCC_199 RLLGHG---WTTRKRKDGTTEWIPPPQLALPGETRHDDIVD---------
TH_3287|M.thermoresistible__bu SGLTEGR--WQATITPTGRLAWTNDHHPPT-----VNHAHHPEELLR---
* : * :
Mflv_3477|M.gilvum_PYR-GCK ------------------------------DPEPP-DQTRSTATEPAAVQ
Mvan_4912|M.vanbaalenii_PYR-1 ------------------------------EPDPHSDNDTAASAKPAEGN
MSMEG_2663|M.smegmatis_MC2_155 SGFTDDTADSRSQTSKTTGSETHAKQAADTEPDTAIARGNDLSDRPAIPP
Mb1159c|M.bovis_AF2122/97 --------------------------------------------------
Rv1128c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2999|M.avium_104 --------------------------------------------------
MMAR_3121|M.marinum_M --------------------------------------------------
MUL_2371|M.ulcerans_Agy99 --------------------------------------------------
MAB_0990c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3287|M.thermoresistible__bu --------------------------------------------------
Mflv_3477|M.gilvum_PYR-GCK AIDDPEAQAPRPADDPGEPGGPAPPEGEAA--------------------
Mvan_4912|M.vanbaalenii_PYR-1 EIGDAQPGAPQPADNPSEPGGPAPPDNQAA--------------------
MSMEG_2663|M.smegmatis_MC2_155 ELLGQNHQQPNTNHHPDTERGDARNSGATGHNQDHSRKNGDRNSGDASKG
Mb1159c|M.bovis_AF2122/97 ------------ADDEGDP-------------------------------
Rv1128c|M.tuberculosis_H37Rv ------------ADDEGDP-------------------------------
MAV_2999|M.avium_104 ----------GGEDDDGDDDEAA---------------------------
MMAR_3121|M.marinum_M ----------DSADDDDEGHGAA---------------------------
MUL_2371|M.ulcerans_Agy99 ----------DSADDDDEGHGAA---------------------------
MAB_0990c|M.abscessus_ATCC_199 ----------QCPHGVGSR-------------------------------
TH_3287|M.thermoresistible__bu ----------AHTDPPEDPG------------------------------
.
Mflv_3477|M.gilvum_PYR-GCK -----------------
Mvan_4912|M.vanbaalenii_PYR-1 -----------------
MSMEG_2663|M.smegmatis_MC2_155 NNGNADGDDGESDCHPA
Mb1159c|M.bovis_AF2122/97 -----------------
Rv1128c|M.tuberculosis_H37Rv -----------------
MAV_2999|M.avium_104 -----------------
MMAR_3121|M.marinum_M -----------------
MUL_2371|M.ulcerans_Agy99 -----------------
MAB_0990c|M.abscessus_ATCC_199 -----------------
TH_3287|M.thermoresistible__bu -----------------