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YSSSREEAVAAFDNLDTALNRVLKVSPDDLTIPECLAMLQRCEKIRRRLPAAEHPFINKLADQTDQTELG GKLPFALAERLHISRGEASRRIHEAADLGPRRTLTGQPLPPLLTATAAAQRAGHLGPAHVQVIRCFLHQL PHHVDLPTREKAEAELATLGGRFRPDQLHKLATKLADCLNPDGNYNDTDRARRRSIILGNQGPDGMSAIS GYLTPEARATVDAVLAKLAAPGMANPADDTPCLAGTPSQAAIEADTRSAGQRHHDGLLAALRALLCSGEL GQHNGLPAAIIVSTSLTELQSRAGHALTGGGTLLPMSDVIRLASHANHYLRIFDHGRELALYHTKRLASP GQRIVLYAKDRGCSFPNCDVPGYLTEVHHVTDFAQCQETDINELTQGCGPHHQLATTGGWITRKRKDGTT EWLPPAHLDHGQPRTNSYFHPEKLLHDSDEDDP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. tuberculosis H37Rv | Rv1702c | - | - | 100% (454) | hypothetical protein Rv1702c |
| M. tuberculosis H37Rv | Rv1128c | - | e-168 | 64.30% (451) | hypothetical protein Rv1128c |
| M. tuberculosis H37Rv | Rv1945 | - | e-153 | 60.79% (454) | hypothetical protein Rv1945 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1728c | - | 0.0 | 100.00% (454) | hypothetical protein Mb1728c |
| M. gilvum PYR-GCK | Mflv_4397 | - | 1e-106 | 47.52% (444) | hypothetical protein Mflv_4397 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0394c | - | 1e-125 | 52.73% (440) | hypothetical protein MAB_0394c |
| M. marinum M | MMAR_1523 | - | 1e-167 | 64.68% (453) | hypothetical protein MMAR_1523 |
| M. avium 104 | MAV_4180 | - | 1e-172 | 66.23% (453) | hypothetical protein MAV_4180 |
| M. smegmatis MC2 155 | MSMEG_6573 | - | 2e-88 | 42.16% (453) | hypothetical protein MSMEG_6573 |
| M. thermoresistible (build 8) | TH_3287 | - | 3e-73 | 39.22% (436) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2371 | - | 1e-158 | 62.00% (450) | hypothetical protein MUL_2371 |
| M. vanbaalenii PYR-1 | Mvan_3231 | - | 1e-101 | 44.96% (456) | hypothetical protein Mvan_3231 |
CLUSTAL 2.0.9 multiple sequence alignment
Rv1702c|M.tuberculosis_H37Rv ---MYS---SSREEAVAAFDNLDTALNRVLKVSPDDLTIPECLAMLQRCE
Mb1728c|M.bovis_AF2122/97 ---MYS---SSREEAVAAFDNLDTALNRVLKVSPDDLTIPECLAMLQRCE
MAV_4180|M.avium_104 ----MS---SDREAVSAAFDVIDAALDDLLDCDYAVLATREKLALLNRCE
MMAR_1523|M.marinum_M ---MSS---MSREEVVAAFDALDAVMARLQDLCFDGLTTPERLALLQRCE
MUL_2371|M.ulcerans_Agy99 ---MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLE
Mflv_4397|M.gilvum_PYR-GCK ---------MSGGDLQTSIAALRAAFEEVAAADVDLLTRPDLVAALDELE
Mvan_3231|M.vanbaalenii_PYR-1 ----MYVRAMSGSDVQATVTALRTAFDDMAACDVDLLTRPDLVAALDELE
MSMEG_6573|M.smegmatis_MC2_155 ---------MDDG-VQDAVAALDAALNTLLTLPHSALTDAELLTICAGLQ
MAB_0394c|M.abscessus_ATCC_199 ---------------MSPIDDLLTTATAVVESSFDELNNPELLSALRQLE
TH_3287|M.thermoresistible__bu MGQQFVTAGAARARVGELLAAVDAAYAEMRALCLDEVGTGFRLELAERLE
. : . : : : :
Rv1702c|M.tuberculosis_H37Rv KIRRRLPAAEHPFINKLADQTDQTELGGK-LPFALAERLHISRGEASRRI
Mb1728c|M.bovis_AF2122/97 KIRRRLPAAEHPFINKLADQTDQTELGGK-LPFALAERLHISRGEASRRI
MAV_4180|M.avium_104 KLRRRLPAVEHPLINALARDASPAELGGR-LSHAIAEATLISRAEAARRV
MMAR_1523|M.marinum_M VARRRLPSIEHPLINQLVEQAGEQELGGK-LAAVLAGRLRVSRGEASRRL
MUL_2371|M.ulcerans_Agy99 VVARRLPAAQYALVNQLDEQPGEAELGGR-LAAVVASRLRITRSEAGRRV
Mflv_4397|M.gilvum_PYR-GCK ELSCQLPAVGHRLLARLQVETSAREMGAKSWNQVLAVRWRISTGEAHRRL
Mvan_3231|M.vanbaalenii_PYR-1 TLGCRLPSVSHRLLARLQAEATPPQMGAKSWKEVLAVRWRISTSEAHRRL
MSMEG_6573|M.smegmatis_MC2_155 DARNRIPAVEHRAIAALSQQTTPAAIGAKSWPLVLATRLGISSKEARRRC
MAB_0394c|M.abscessus_ATCC_199 IAQRKITAASHTLTARLVQRGSPVALGGTSFAEVLARYLSITTATARRRL
TH_3287|M.thermoresistible__bu TQCRINRGLMYRVFAQLADPPDEPAMVPA-VRDRLWARLRITPGEVKRRL
. : * : : :: . **
Rv1702c|M.tuberculosis_H37Rv HEAADLGPRRTLTGQPLPPLLTATAAAQRAGHLGPAHVQVIRCFLHQLPH
Mb1728c|M.bovis_AF2122/97 HEAADLGPRRTLTGQPLPPLLTATAAAQRAGHLGPAHVQVIRCFLHQLPH
MAV_4180|M.avium_104 HTAADLGPRVGLTGEPLPPVLAATAAAQRAGSLGPEQVAVIRKFCHQLPG
MMAR_1523|M.marinum_M REAADLGPRRALTGEQLAPLLSATASAVRQGRIGAGHVRVIREFCGQVPA
MUL_2371|M.ulcerans_Agy99 AEAAEVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRQLPA
Mflv_4397|M.gilvum_PYR-GCK TEAALLAPRQSLTGTPLPPALPATAVAQSRGLINAEHVEVIRKAVKKLPG
Mvan_3231|M.vanbaalenii_PYR-1 TEAAVLAPRQAMTGEALAPVLPATAAAQAHGLINAEHVEVIRKTMAKVPG
MSMEG_6573|M.smegmatis_MC2_155 TDAAELGPRVSMTGEALAPKREHIAAAQADGTLTPDHVAELFKFFTKCPD
MAB_0394c|M.abscessus_ATCC_199 ADAAHLGPRRALTGEPLRPALPYVAHALREGRLGDEHVRIIRRFFDVLPD
TH_3287|M.thermoresistible__bu RVAALLRPRRRLSGPPLPPVLARVAGAVESGLLGEEHLRVITTVMAALPS
** : ** ::* : * * * * : :: : *
Rv1702c|M.tuberculosis_H37Rv HVDLPTREKAEAELATLGGRFRPDQLHKLATKLADCLNPDG-NYNDTDRA
Mb1728c|M.bovis_AF2122/97 HVDLPTREKAEAELATLGGRFRPDQLHKLATKLADCLNPDG-NYNDTDRA
MAV_4180|M.avium_104 WIDQATRERAETDLAREGTRYRPEQLAALAGTLADCLNPDG-LYRDEDRA
MMAR_1523|M.marinum_M EVDLETRERAEAHLARLAGQFRPDQLAKLAQRLMDCVNPDG-RYSDEDRA
MUL_2371|M.ulcerans_Agy99 GVDVGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPDG-RHSDEDRA
Mflv_4397|M.gilvum_PYR-GCK WVDVATREQFEVNLVRTAVGNGPKELRDAAELTLFLLDQDGPEPDDTERA
Mvan_3231|M.vanbaalenii_PYR-1 FVDTATRERIEVDLVRTAVGNGPKELKDSADRTLFLLDQDGPEPDERERA
MSMEG_6573|M.smegmatis_MC2_155 WVTYAEQCRLEEKLVTGAIGADPETVRQAVDHAVFLLDQDGPAPTDNPPT
MAB_0394c|M.abscessus_ATCC_199 AVDADTREAAEKQLASMGTEFGPEQLRAGADRIAALVNPDG-RFSDIDRA
TH_3287|M.thermoresistible__bu AVSVTDREAVEASLIAEAARSDAGIVRQVGRRIEEIFNPDG-HYDDQDRA
: : * * . . : .: ** : :
Rv1702c|M.tuberculosis_H37Rv RRRSIILGNQGPDGMSAISGYLTPEARATVDAVLAKLAAP----------
Mb1728c|M.bovis_AF2122/97 RRRSIILGNQGPDGMSAISGYLTPEARATVDAVLAKLAAP----------
MAV_4180|M.avium_104 RRRSLTLGNQHADGMSELRGLLTPELRATLEAVLAKLAAP----------
MMAR_1523|M.marinum_M RRRGLTLGRQGRDGMSRISGWLTPEARAGLDAVLAKLAAP----------
MUL_2371|M.ulcerans_Agy99 RRRGLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAP----------
Mflv_4397|M.gilvum_PYR-GCK RKRGLTKGKQRPDGMIDLAGTLTPEAWAVLEVIFAKYAAP----------
Mvan_3231|M.vanbaalenii_PYR-1 RKRAVTKHKQREDGMVDVSATLTPEAWAVWEAIFAKFAAP----------
MSMEG_6573|M.smegmatis_MC2_155 KPFGITFGPQQPDGSYHLRGKVSAEFKATFDPIDEKLAAP----------
MAB_0394c|M.abscessus_ATCC_199 RRRGISIGRQGADGMSALSGLLDPETRAYFDAVLSKLAAP----------
TH_3287|M.thermoresistible__bu RRRGIHLGDQQRDGMSAISGWIDPQLRAYLEAVTAAVRPGRHLPHTTTDT
: .: * ** : . : .: * : : .
Rv1702c|M.tuberculosis_H37Rv -GMANPADDT--PCLAGTPSQAA---------IEA---DTRSAGQRHHDG
Mb1728c|M.bovis_AF2122/97 -GMANPADDT--PCLAGTPSQAA---------IEA---DTRSAGQRHHDG
MAV_4180|M.avium_104 -GMCNPLDES--PCVDGTPTEQA---------IEG---DTRSAAQRNHDG
MMAR_1523|M.marinum_M -GMCNPDDES--PVVQAPAGADA---------VSR---DRRSVGQRHHDG
MUL_2371|M.ulcerans_Agy99 -GMCNPEDEA--AVVDGPVSRDA---------ADR---DSRSVSQRQHDG
Mflv_4397|M.gilvum_PYR-GCK -GMCNPADPE--PCTYGTPTQAQ---------IDN---DQRSLAQRQHDA
Mvan_3231|M.vanbaalenii_PYR-1 -GMCNPDDPE--PCTSGTPSQAQ---------IDH---DQRSLAQRQHDA
MSMEG_6573|M.smegmatis_MC2_155 -GMCNPTDQT--PCISGTPSQQQ---------IDS---DQRGAPERRHDA
MAB_0394c|M.abscessus_ATCC_199 -GMCDPRDES--PMTEGEPDSAA---------AER---DTRTSAQRNHDG
TH_3287|M.thermoresistible__bu TGTTGTTETTGTAGTAGTAATAADTAADGVGDIDTGGVDLRSAAQRRHDG
* .. : . . . * * :*.**.
Rv1702c|M.tuberculosis_H37Rv LLAALRALLCSGELGQHNGLPAAIIVSTSLTELQSRA-----------GH
Mb1728c|M.bovis_AF2122/97 LLAALRALLCSGELGQHNGLPAAIIVSTSLTELQSRA-----------GH
MAV_4180|M.avium_104 LLAGLRALLASGNLGQHNGLPASIIVTTTLADLQAAA-----------GK
MMAR_1523|M.marinum_M LNAAVRALLASGDLGQHNGLPASIIVTTTLGELQRAC-----------GR
MUL_2371|M.ulcerans_Agy99 FNAALRAVLASGELGQHNGLPASIIVSTTLKELEAAA-----------GR
Mflv_4397|M.gilvum_PYR-GCK LVAVGRIALMSGELGQLNGLPVSIIIRTTLQDLESRA-----------GV
Mvan_3231|M.vanbaalenii_PYR-1 LLAAGRIALMSGELGKLNGLPVSVIIRTTLQDLESRA-----------GV
MSMEG_6573|M.smegmatis_MC2_155 MLTAMRLLLAHKDLGQINGLPATLLVTTTLQELEKAA-----------GV
MAB_0394c|M.abscessus_ATCC_199 LRACLRSTLASGKLGAHRGLPVTVVVSTTLRELQSAA-----------GR
TH_3287|M.thermoresistible__bu LTLGLKIAVASGRLGSHRGHPVTVIVRTTLGELNQAAHAVADPRVSMPGP
: : : ** .* *.:::: *:* :*: . *
Rv1702c|M.tuberculosis_H37Rv ALTGGGTLLPMSDVIRLASHANHYLRIFD--HGRELALYHTKRLASPGQR
Mb1728c|M.bovis_AF2122/97 ALTGGGTLLPMSDVIRLASHANHYLRIFD--HGRELALYHTKRLASPGQR
MAV_4180|M.avium_104 GLTGGGTLLPMSDVIRLSRHAHHYLAIFD--HGKALALYHTKRLASPAQR
MMAR_1523|M.marinum_M GLTGGGTVLPISDVIRLARHAHHYLAVFD--RGKAVGLYHAKRLATAGQR
MUL_2371|M.ulcerans_Agy99 GLTGGGTLLPMSDVIRLARHAHHYLAVFD--RGEAIGLYHAKRLATPGQR
Mflv_4397|M.gilvum_PYR-GCK GTTGGGTVVPIKDVIRMAGHANHYLAVFDRATGSALDLFRTRRVASPAQR
Mvan_3231|M.vanbaalenii_PYR-1 GVTGGGTVMPIAEVIRMAGHANHYLAVFDRATGSALDLFRTRRIASPAQR
MSMEG_6573|M.smegmatis_MC2_155 AITAGGTKLSIPDLIRLASQALHYLAVYDEHTGIPLYLGRARRTASAGQR
MAB_0394c|M.abscessus_ATCC_199 AISGSGNLVPIPDLIRMATHAFHYLTIFGD-DGRPLHLGRSKRIATPDQR
TH_3287|M.thermoresistible__bu ARTGGTGVLPMRELIRMAADAIHYLAVFDDHTERPLYLGRQKRIATADQR
. :.. :.: ::**:: .* *** ::. : * : :* *:. **
Rv1702c|M.tuberculosis_H37Rv IVLYAKDRGCSFPNCDVPGYLTEVHHVT-DFAQCQETDINELTQGCGPHH
Mb1728c|M.bovis_AF2122/97 IVLYAKDRGCSFPNCDVPGYLTEVHHVT-DFAQCQETDINELTQGCGPHH
MAV_4180|M.avium_104 IVLYAKDRGCTAPGCTVPGYYAEVHHCT-DYATCHTTDINDLTFACGPHH
MMAR_1523|M.marinum_M LVLYAKDRGCTRPGCDVPGYQCEVHHVA-AWATSGRTDIDQLTLACGPDH
MUL_2371|M.ulcerans_Agy99 IVLYAKDRGCTRPGCDVAGYQCEVHHVA-AWAISGRTDINQLTLACGPDH
Mflv_4397|M.gilvum_PYR-GCK VMLIARDGGCTKPCCTVGAYGCQVHHAETDYAHGGNTNIDELGLACGPDN
Mvan_3231|M.vanbaalenii_PYR-1 IMLIARDGGCTKPGCTVGAYGCQGHHVEADFAKGGNTNVDELGLACGPDN
MSMEG_6573|M.smegmatis_MC2_155 LAIWARDRGCTRPGCTANGYRCQAHHATTDYAKGGLTDADALALACGCDN
MAB_0394c|M.abscessus_ATCC_199 IVLHAKDRGCSAPGCTVPGYLCQVHHVD-DWRDDGPTDIDNLTFACGPHH
TH_3287|M.thermoresistible__bu LICYARDGGCTAPGCGEPGYHAETHHQP-AWEDGGLTDADHLFFACGPHH
: *:* **: * * .* : ** : *: : * .** .:
Rv1702c|M.tuberculosis_H37Rv QLATT--GGWITRKR-KDGTTEWLPPAHLDHGQPRTNSYFHPEKLLHDSD
Mb1728c|M.bovis_AF2122/97 QLATT--GGWITRKR-KDGTTEWLPPAHLDHGQPRTNSYFHPEKLLHDSD
MAV_4180|M.avium_104 RLLQP--GAWTTHKN-ARGETQWLPPPHLDRNQPRTNTFHHPEKLLRGED
MMAR_1523|M.marinum_M KLLEQ--G-WRTRKN-AHGDTEWLPPPHLDHGQPRTNTYHHPEKLLRDSA
MUL_2371|M.ulcerans_Agy99 KLLEQ--G-WRTRKN-AHGDTEWLPPPHLDHGQPRTNSYHHPEKLLRDSA
Mflv_4397|M.gilvum_PYR-GCK RSVT--EGGWTTRIN-DRCEVEWIPPPGLDTGQARVNTYHRPERLLAPPD
Mvan_3231|M.vanbaalenii_PYR-1 RSVDN-NGGWTTRMN-ERCEVEWIPPPSLDTGQARINNYHRPERLLHPPD
MSMEG_6573|M.smegmatis_MC2_155 RLVGEAPNKWTTRIN-NHGQCEWIPPDLLDRGQHRTNTYHHPETLLADIN
MAB_0394c|M.abscessus_ATCC_199 RLLQQ---GWTTRKRRSDGITEWIPPPHLDTGQSRTNDHHHPERFIRRF-
TH_3287|M.thermoresistible__bu SGLTE--GRWQATIT-PTGRLAWTN----DHHPPTVNHAHHPEELLRAHT
* : * * * .:** ::
Rv1702c|M.tuberculosis_H37Rv -------EDDP---------------------------------------
Mb1728c|M.bovis_AF2122/97 -------EDDP---------------------------------------
MAV_4180|M.avium_104 GG-----EDDDGDDDEAA--------------------------------
MMAR_1523|M.marinum_M AD-----EGEEGG-------------------------------------
MUL_2371|M.ulcerans_Agy99 DD-----DDEGHGAA-----------------------------------
Mflv_4397|M.gilvum_PYR-GCK -------DPEPPNQTRT---------------------------TATEPV
Mvan_3231|M.vanbaalenii_PYR-1 -------EPEPQGHNDT---------------------------EAEIES
MSMEG_6573|M.smegmatis_MC2_155 RDQKTDGDNREQHHTDTGADTGTVHVNGHGEKPAIPPELLDQGQQRTAPY
MAB_0394c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3287|M.thermoresistible__bu DP------PEDPG-------------------------------------
Rv1702c|M.tuberculosis_H37Rv --------------------------------------------------
Mb1728c|M.bovis_AF2122/97 --------------------------------------------------
MAV_4180|M.avium_104 --------------------------------------------------
MMAR_1523|M.marinum_M --------------------------------------------------
MUL_2371|M.ulcerans_Agy99 --------------------------------------------------
Mflv_4397|M.gilvum_PYR-GCK EDQAIDDP---ETDAPPPLDDPGEPGGPAP---------PDNRAA-----
Mvan_3231|M.vanbaalenii_PYR-1 AGSAQGNPRGDETNGPRPTDDAGKPGGPAP---------PGDQAA-----
MSMEG_6573|M.smegmatis_MC2_155 HQAEVPPVNTRDTRSSTTTRDANRHNGNGDRNSAENRNGPSKNAAGDDDE
MAB_0394c|M.abscessus_ATCC_199 --------------------------------------------------
TH_3287|M.thermoresistible__bu --------------------------------------------------
Rv1702c|M.tuberculosis_H37Rv --
Mb1728c|M.bovis_AF2122/97 --
MAV_4180|M.avium_104 --
MMAR_1523|M.marinum_M --
MUL_2371|M.ulcerans_Agy99 --
Mflv_4397|M.gilvum_PYR-GCK --
Mvan_3231|M.vanbaalenii_PYR-1 --
MSMEG_6573|M.smegmatis_MC2_155 PR
MAB_0394c|M.abscessus_ATCC_199 --
TH_3287|M.thermoresistible__bu --