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SSIADSDAAEVLAGLCGAVDALSELDTSALTRHDRLTILRDVETLLRRIPTATHGIVNELVAGHVPGQFG GASLGDVLADTLRITRADARRRIRDAAELAPTVALTGTSIEPVLAATSAAQRAGTAGGDHIAVIRRFWDR VPRTVDVQTRMTAERQLARLTQTLRPDELGKAAQRLLAHLDPDGSLTSDTDRARRRGFRMGRQGADLMTA GAFDLDPELRSYLDAIFAKYAAPGVCHPDDENPCVDGDPDSDAARHDVRSVAQRQHDALKAVCRSILCSG ELGHHRGLPVTTIVTTTLRELESGAGHAATGGGSLLPMPDPIRMASHAHHYLAVFDDDGRALYLGRAKRI ATADQRIVLTAKERGCTYPGCDRPAYHCQAHHMDEWAAGGNTDIASLTLGCERHHKLLGTDHQCWQTIRG PDGRTWWIPPAHVDPYRTPRSNWFHHPDGYLRE*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2374c | - | - | 100% (454) | hypothetical protein MAB_2374c |
| M. abscessus ATCC 19977 | MAB_0394c | - | e-119 | 51.50% (433) | hypothetical protein MAB_0394c |
| M. abscessus ATCC 19977 | MAB_0990c | - | e-115 | 52.06% (413) | hypothetical protein MAB_0990c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1159c | - | 1e-111 | 46.76% (447) | hypothetical protein Mb1159c |
| M. gilvum PYR-GCK | Mflv_1835 | - | 1e-93 | 44.25% (452) | hypothetical protein Mflv_1835 |
| M. tuberculosis H37Rv | Rv1128c | - | 1e-111 | 46.76% (447) | hypothetical protein Rv1128c |
| M. leprae Br4923 | - | - | - | - | - |
| M. marinum M | MMAR_1523 | - | 1e-118 | 49.12% (454) | hypothetical protein MMAR_1523 |
| M. avium 104 | MAV_3664 | - | 1e-113 | 50.11% (447) | hypothetical protein MAV_3664 |
| M. smegmatis MC2 155 | MSMEG_6573 | - | 2e-78 | 37.92% (451) | hypothetical protein MSMEG_6573 |
| M. thermoresistible (build 8) | TH_3287 | - | 3e-65 | 39.09% (417) | PUTATIVE conserved hypothetical protein |
| M. ulcerans Agy99 | MUL_2371 | - | 1e-118 | 50.98% (457) | hypothetical protein MUL_2371 |
| M. vanbaalenii PYR-1 | Mvan_3050 | - | 5e-98 | 44.58% (480) | hypothetical protein Mvan_3050 |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_1835|M.gilvum_PYR-GCK -MYVRV---MSGGDLQTRIAVLRAAFDEVAACEIELLTRPDLVAALDELE
MSMEG_6573|M.smegmatis_MC2_155 ---------MDDG-VQDAVAALDAALNTLLTLPHSALTDAELLTICAGLQ
Mvan_3050|M.vanbaalenii_PYR-1 ----MG---CSREDVLGAFDALDAVVESILALDYDALSAAERVRLEARLE
MAB_2374c|M.abscessus_ATCC_199 ---MSS---IADSDAAEVLAGLCGAVDALSELDTSALTRHDRLTILRDVE
Mb1159c|M.bovis_AF2122/97 ---MCS----TREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCE
Rv1128c|M.tuberculosis_H37Rv ---MCS----TREEITEAFASLATALSRVLGLTFDALTTPERLALLEHCE
MMAR_1523|M.marinum_M ---MSS---MSREEVVAAFDALDAVMARLQDLCFDGLTTPERLALLQRCE
MUL_2371|M.ulcerans_Agy99 ---MHSNGCSDRESVVATLDRLDRAVDALVEVSFEALTTPERLRVLERLE
MAV_3664|M.avium_104 ---MHS--IEVPAEVRAALDALDTADAAIRALDFDALHPVVRLRALERME
TH_3287|M.thermoresistible__bu MGQQFVTAGAARARVGELLAAVDAAYAEMRALCLDEVGTGFRLELAERLE
. : . : . : : :
Mflv_1835|M.gilvum_PYR-GCK ELSCQLPAVGHRLLARLQAEGTPQQMGAKNWSEVLRVRWRISGSEAHRRL
MSMEG_6573|M.smegmatis_MC2_155 DARNRIPAVEHRAIAALSQQTTPAAIGAKSWPLVLATRLGISSKEARRRC
Mvan_3050|M.vanbaalenii_PYR-1 RNLRRIPTVEHELLASVIAETEPARLGEGSWKKVLTTALRISGAEAGRRL
MAB_2374c|M.abscessus_ATCC_199 TLLRRIPTATHGIVNELVAGHVPGQFGGASLGDVLADTLRITRADARRRI
Mb1159c|M.bovis_AF2122/97 TARRQLPSVEHTLINQIGEQSTEEELGG-KLGLTLADRLRITRSEAKRRV
Rv1128c|M.tuberculosis_H37Rv TARRQLPSVEHTLINQIGEQSTEEELGG-KLGLTLADRLRITRSEAKRRV
MMAR_1523|M.marinum_M VARRRLPSIEHPLINQLVEQAGEQELGG-KLAAVLAGRLRVSRGEASRRL
MUL_2371|M.ulcerans_Agy99 VVARRLPAAQYALVNQLDEQPGEAELGG-RLAAVVASRLRITRSEAGRRV
MAV_3664|M.avium_104 ASRRRQIAVSHDVIAGLAGEG-PANVGG-PVHKVIADRLRISYAEACRRL
TH_3287|M.thermoresistible__bu TQCRINRGLMYRVFAQLADPPDEPAMVP-AVRDRLWARLRITPGEVKRRL
: . : . : :: :. **
Mflv_1835|M.gilvum_PYR-GCK TEAALLAPRPSLTGPALPPQLAATAIAQARGLINAEHVAVIRKAVKKLPG
MSMEG_6573|M.smegmatis_MC2_155 TDAAELGPRVSMTGEALAPKREHIAAAQADGTLTPDHVAELFKFFTKCPD
Mvan_3050|M.vanbaalenii_PYR-1 KRAKTLGPRRGLTGTPLPPLWESTAAAQAQGLLSEEHVAVIAAFHKRLPA
MAB_2374c|M.abscessus_ATCC_199 RDAAELAPTVALTGTSIEPVLAATSAAQRAGTAGGDHIAVIRRFWDRVPR
Mb1159c|M.bovis_AF2122/97 AEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPS
Rv1128c|M.tuberculosis_H37Rv AEAADLGQRRALTGEPLPPLLTATAKAQRHGLIGDGHVEVIRAFVHRLPS
MMAR_1523|M.marinum_M REAADLGPRRALTGEQLAPLLSATASAVRQGRIGAGHVRVIREFCGQVPA
MUL_2371|M.ulcerans_Agy99 AEAAEVGPRRALSGQPVGPVLTATAAALRQGVVGEGHVRVIRDFFRQLPA
MAV_3664|M.avium_104 REAKQLSPRLTLTGQELPPELPATAGVWREGMLDGQHLRVIEKFVRDLPE
TH_3287|M.thermoresistible__bu RVAALLRPRRRLSGPPLPPVLARVAGAVESGLLGEEHLRVITTVMAALPS
* : ::* : * : . * *: : *
Mflv_1835|M.gilvum_PYR-GCK WVDVATREQFEVNLVRTAVGHGPKELNDAADRMLFLLDQDGPEPDDAERG
MSMEG_6573|M.smegmatis_MC2_155 WVTYAEQCRLEEKLVTGAIGADPETVRQAVDHAVFLLDQDGPAPTDNPPT
Mvan_3050|M.vanbaalenii_PYR-1 WVDIETRAEADRQLAHAGSGLDPEGLDEAAGVLLAMINPDGAQPCDKERA
MAB_2374c|M.abscessus_ATCC_199 TVDVQTRMTAERQLARLTQTLRPDELGKAAQRLLAHLDPDGSLTSDTDRA
Mb1159c|M.bovis_AF2122/97 WVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDG-DYTDEDRA
Rv1128c|M.tuberculosis_H37Rv WVDLKTLEKAERDLAKQATQYRPDQLAKLAARIMDCLNPDG-DYTDEDRA
MMAR_1523|M.marinum_M EVDLETRERAEAHLARLAGQFRPDQLAKLAQRLMDCVNPDG-RYSDEDRA
MUL_2371|M.ulcerans_Agy99 GVDVGTRDRAEAHLAKLATQFRPDQLARLAGRLMDCLNPDG-RHSDEDRA
MAV_3664|M.avium_104 TTPVRALEEAERFLAHQATLLRPDQLEKVAHQCALRINPDG-KFSDADRA
TH_3287|M.thermoresistible__bu AVSVTDREAVEASLIAEAARSDAGIVRQVGRRIEEIFNPDG-HYDDQDRA
. : * . : .: ** *
Mflv_1835|M.gilvum_PYR-GCK RKRGVSIGRQGAEAMSALTGQLTPEARAVWEAIFAKYAAPGMCNPDDEQ-
MSMEG_6573|M.smegmatis_MC2_155 KPFGITFGPQQPDGSYHLRGKVSAEFKATFDPIDEKLAAPGMCNPTDQT-
Mvan_3050|M.vanbaalenii_PYR-1 RKRGIRISKQHPDGTATISGTLTPEALAIWQAIFAKEAAPGANNPESEHT
MAB_2374c|M.abscessus_ATCC_199 RRRGFRMGRQGADLMTAGAFDLDPELRSYLDAIFAKYAAPGVCHPDDEN-
Mb1159c|M.bovis_AF2122/97 RRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQKA-
Rv1128c|M.tuberculosis_H37Rv RRRGLTLGKQDVDGMSRLSGYVTPELRATIEAVWAKLAAPGMCNPEQKA-
MMAR_1523|M.marinum_M RRRGLTLGRQGRDGMSRISGWLTPEARAGLDAVLAKLAAPGMCNPDDES-
MUL_2371|M.ulcerans_Agy99 RRRGLSLGRQGLDGMSRISGWLTPEARAGLEAVWAKLAAPGMCNPEDEA-
MAV_3664|M.avium_104 RQRGFTWCGQRADEMSLGKLWASPELRANLDAWLARFAAPGMCNPDDEV-
TH_3287|M.thermoresistible__bu RRRGIHLGDQQRDGMSAISGWIDPQLRAYLEAVTAAVR-PGRHLPHTTTD
: *. * : .: : :. ** *
Mflv_1835|M.gilvum_PYR-GCK -PCTSG------------------------------TPSQAQIDGDHRSL
MSMEG_6573|M.smegmatis_MC2_155 -PCISG------------------------------TPSQQQIDSDQRGA
Mvan_3050|M.vanbaalenii_PYR-1 EDSTSGGAADDASDAPGDHAGAASSAASGASDAAEHDPQPERCGSDTRTQ
MAB_2374c|M.abscessus_ATCC_199 -PCVDG------------------------------DPDSDAARHDVRSV
Mb1159c|M.bovis_AF2122/97 -PCVNG------------------------------APSKEQARRDTRSC
Rv1128c|M.tuberculosis_H37Rv -PCVNG------------------------------APSKEQARRDTRSC
MMAR_1523|M.marinum_M -PVVQA------------------------------PAGADAVSRDRRSV
MUL_2371|M.ulcerans_Agy99 -AVVDG------------------------------PVSRDAADRDSRSV
MAV_3664|M.avium_104 -PCVAG------------------------------EPDEESATKDSRTP
TH_3287|M.thermoresistible__bu TTGTTG------TTETTGTAGTAGTAATAADTAADGVGDIDTGGVDLRSA
. * *
Mflv_1835|M.gilvum_PYR-GCK AQRQHDALLAVGRIALMSGELGQLNGLPVSVIIRTTLQDLESRA------
MSMEG_6573|M.smegmatis_MC2_155 PERRHDAMLTAMRLLLAHKDLGQINGLPATLLVTTTLQELEKAA------
Mvan_3050|M.vanbaalenii_PYR-1 AQRNHDAFLAVGRRLLESGELGTHNGLPVTVIVSTTLQELEKGA------
MAB_2374c|M.abscessus_ATCC_199 AQRQHDALKAVCRSILCSGELGHHRGLPVTTIVTTTLRELESGA------
Mb1159c|M.bovis_AF2122/97 PQRNHDALNAGLRSLLTSGNLGQHNGLPASIIVTTTLKDLEAAA------
Rv1128c|M.tuberculosis_H37Rv PQRNHDALNAELRSLLTSGNLGQHNGLPASIIVTTTLKDLEAAA------
MMAR_1523|M.marinum_M GQRHHDGLNAAVRALLASGDLGQHNGLPASIIVTTTLGELQRAC------
MUL_2371|M.ulcerans_Agy99 SQRQHDGFNAALRAVLASGELGQHNGLPASIIVSTTLKELEAAA------
MAV_3664|M.avium_104 AQRQHDALNALVRGRLGDPKLGLHNGLPVTVIVSTTLRELTTGA------
TH_3287|M.thermoresistible__bu AQRRHDGLTLGLKIAVASGRLGSHRGHPVTVIVRTTLGELNQAAHAVADP
:*.**.: : : ** .* *.: :: *** :* .
Mflv_1835|M.gilvum_PYR-GCK -----GIGVSGGGTKLPIRDVIRMAGHANHYLAVFDRATGSALDLFRTRR
MSMEG_6573|M.smegmatis_MC2_155 -----GVAITAGGTKLSIPDLIRLASQALHYLAVYDEHTGIPLYLGRARR
Mvan_3050|M.vanbaalenii_PYR-1 -----GVAVTGGGSLLPMPDLIRLAARAHHYLYVYDQHSGKSLYLGRAKR
MAB_2374c|M.abscessus_ATCC_199 -----GHAATGGGSLLPMPDPIRMASHAHHYLAVFDDD-GRALYLGRAKR
Mb1159c|M.bovis_AF2122/97 -----GAGLTGGGTILPISDVIRLARHANHYLAIFDRG--KALALYHTKR
Rv1128c|M.tuberculosis_H37Rv -----GAGLTGGGTILPISDVIRLARHANHYLAIFDRG--KALALYHTKR
MMAR_1523|M.marinum_M -----GRGLTGGGTVLPISDVIRLARHAHHYLAVFDRG--KAVGLYHAKR
MUL_2371|M.ulcerans_Agy99 -----GRGLTGGGTLLPMSDVIRLARHAHHYLAVFDRG--EAIGLYHAKR
MAV_3664|M.avium_104 -----GRAVTGGGTLLPMRDVIRMARHAYHYLAVFDEHSSRPLYLGRSRR
TH_3287|M.thermoresistible__bu RVSMPGPARTGGTGVLPMRELIRMAADAIHYLAVFDDHTERPLYLGRQKR
* . :.* *.: : **:* * *** ::* .: * : :*
Mflv_1835|M.gilvum_PYR-GCK VASPAQRVMLIARDGGCTKPCCTVGAYGCQVHHAEADYAHGGNTNIDELG
MSMEG_6573|M.smegmatis_MC2_155 TASAGQRLAIWARDRGCTRPGCTANGYRCQAHHATTDYAKGGLTDADALA
Mvan_3050|M.vanbaalenii_PYR-1 LANAAQRIVLHARDRGCTRPGCTAPGYWCQAHHASADFVDGGLTNIDDLT
MAB_2374c|M.abscessus_ATCC_199 IATADQRIVLTAKERGCTYPGCDRPAYHCQAHHMD-EWAAGGNTDIASLT
Mb1159c|M.bovis_AF2122/97 LASPAQRIMLYAKDSGCSAPGCDVPGYYCEVHHVT-PYAQCRNTDVNDLT
Rv1128c|M.tuberculosis_H37Rv LASPAQRIMLYAKDSGCSAPGCDVPGYYCEVHHVT-PYAQCRNTDVNDLT
MMAR_1523|M.marinum_M LATAGQRLVLYAKDRGCTRPGCDVPGYQCEVHHVA-AWATSGRTDIDQLT
MUL_2371|M.ulcerans_Agy99 LATPGQRIVLYAKDRGCTRPGCDVAGYQCEVHHVA-AWAISGRTDINQLT
MAV_3664|M.avium_104 VASPDQRVVLYAKDRGCTHPGCDAPGYWCEVHHLD-EWATGGLTDVDNLT
TH_3287|M.thermoresistible__bu IATADQRLICYARDGGCTAPGCGEPGYHAETHHQP-AWEDGGLTDADHLF
*.. **: *:: **: * * .* .:.** : *: *
Mflv_1835|M.gilvum_PYR-GCK LACGPDNRSVTDGG--WTTRMNDRCEVEWIPPPGLD-TGQARVNTYHRPE
MSMEG_6573|M.smegmatis_MC2_155 LACGCDNRLVGEAPNKWTTRINNHGQCEWIPPDLLD-RGQHRTNTYHHPE
Mvan_3050|M.vanbaalenii_PYR-1 LACPCDHRMLDNTG--WRTRKNGKNQTEWLPPPDLD-TGQHRVNGHHHPE
MAB_2374c|M.abscessus_ATCC_199 LGCERHHKLLGTDHQCWQTIRGPDGRTWWIPPAHVDPYRTPRSNWFHHPD
Mb1159c|M.bovis_AF2122/97 LGCGGHHPLA-ERG--WTTRKNAHGDTEWLPPPHLD-HGQPRVNTFHHPE
Rv1128c|M.tuberculosis_H37Rv LGCGGHHPLA-ERG--WTTRKNAHGDTEWLPPPHLD-HGQPRVNTFHHPE
MMAR_1523|M.marinum_M LACGPDHKLL-EQG--WRTRKNAHGDTEWLPPPHLD-HGQPRTNTYHHPE
MUL_2371|M.ulcerans_Agy99 LACGPDHKLL-EQG--WRTRKNAHGDTEWLPPPHLD-HGQPRTNSYHHPE
MAV_3664|M.avium_104 FACGTHHKLI-ENG--WRTNKLADGRTAWIPPPQWD--RGARTNEFHHPE
TH_3287|M.thermoresistible__bu FACGPHHSGLTEGR--WQATITPTGRLAWTN----D-HHPPTVNHAHHPE
:.* .: * : * * * *:*:
Mflv_1835|M.gilvum_PYR-GCK RLLRPEDPEPLGDNDSQASRPADDPGEPG---------GPAPP-----EG
MSMEG_6573|M.smegmatis_MC2_155 TLLADINRDQKTDGDNREQHHTDTGADTGTVHVNGHGEKPAIPPELLDQG
Mvan_3050|M.vanbaalenii_PYR-1 RYLLPEDDLPEDDQGP----------------------------------
MAB_2374c|M.abscessus_ATCC_199 GYLRE---------------------------------------------
Mb1159c|M.bovis_AF2122/97 KLLADDEGDP----------------------------------------
Rv1128c|M.tuberculosis_H37Rv KLLADDEGDP----------------------------------------
MMAR_1523|M.marinum_M KLLRDSAADEGEEGG-----------------------------------
MUL_2371|M.ulcerans_Agy99 KLLRDSADDDDEGHGAA---------------------------------
MAV_3664|M.avium_104 RAFDGEDP------------------------------------------
TH_3287|M.thermoresistible__bu ELLRAHTDPPEDPG------------------------------------
:
Mflv_1835|M.gilvum_PYR-GCK EAA-----------------------------------------------
MSMEG_6573|M.smegmatis_MC2_155 QQRTAPYHQAEVPPVNTRDTRSSTTTRDANRHNGNGDRNSAENRNGPSKN
Mvan_3050|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_2374c|M.abscessus_ATCC_199 --------------------------------------------------
Mb1159c|M.bovis_AF2122/97 --------------------------------------------------
Rv1128c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_1523|M.marinum_M --------------------------------------------------
MUL_2371|M.ulcerans_Agy99 --------------------------------------------------
MAV_3664|M.avium_104 --------------------------------------------------
TH_3287|M.thermoresistible__bu --------------------------------------------------
Mflv_1835|M.gilvum_PYR-GCK ---------
MSMEG_6573|M.smegmatis_MC2_155 AAGDDDEPR
Mvan_3050|M.vanbaalenii_PYR-1 ---------
MAB_2374c|M.abscessus_ATCC_199 ---------
Mb1159c|M.bovis_AF2122/97 ---------
Rv1128c|M.tuberculosis_H37Rv ---------
MMAR_1523|M.marinum_M ---------
MUL_2371|M.ulcerans_Agy99 ---------
MAV_3664|M.avium_104 ---------
TH_3287|M.thermoresistible__bu ---------