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RFTVYLPNCMHVAAITQPWEHQLSGADIARVAQHAEQLGYSMVFLPEHFLTPTAHLELSGDHYFDATTAQ AFVAGATSTITVGSMVTILPLHNPIIAAKQIATFDWLSGGRAQTTVGVGWLKEEYDAIGVPFTKRGRMAD EYLEAMFELWHSDSPSYDGEFVKFDDVAFGPKPISTPHPTVWMGGDADAVLRRAARFGDGWAPWLTKPDE LPAKLDYLRSQPGFDDRPFSVFYSLAVLSVGQEHAIVDDPNAQFGQSAQQVIDNCNMLAERGVTDTWVNP PALDGLSAYLDHMQWVAEEIIPKVG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2659 | - | - | 100% (306) | hypothetical protein MAV_2659 |
| M. avium 104 | MAV_1954 | - | e-158 | 83.66% (306) | hypothetical protein MAV_1954 |
| M. avium 104 | MAV_3045 | - | 5e-94 | 51.80% (305) | hypothetical protein MAV_3045 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3106c | - | 2e-27 | 32.86% (210) | hypothetical protein Mb3106c |
| M. gilvum PYR-GCK | Mflv_1590 | - | 4e-95 | 50.82% (305) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3079c | - | 2e-27 | 32.86% (210) | hypothetical protein Rv3079c |
| M. leprae Br4923 | MLBr_00131 | - | 6e-11 | 25.50% (200) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 7e-32 | 37.38% (206) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_1586 | - | 2e-35 | 34.28% (283) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_0654 | - | 1e-93 | 49.84% (305) | hypothetical protein MSMEG_0654 |
| M. thermoresistible (build 8) | TH_2945 | - | 5e-95 | 52.46% (305) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_3448 | - | 8e-35 | 33.92% (283) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5167 | - | 3e-93 | 49.84% (305) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3106c|M.bovis_AF2122/97 ---------MQFGVLTFVTDEGIGPAELGAALEHRGFESLFLAEHT-HIP
Rv3079c|M.tuberculosis_H37Rv ---------MQFGVLTFVTDEGIGPAELGAALEHRGFESLFLAEHT-HIP
Mflv_1590|M.gilvum_PYR-GCK -----MQLVFPLPHMLRLPAMSQPWEGSVTGADQTRMAKCADAWGY-DMI
Mvan_5167|M.vanbaalenii_PYR-1 -----MRLVFALPHMLRLPAMSQPWEASVTGADQTRMARCADQWGY-DMI
MSMEG_0654|M.smegmatis_MC2_155 MKEFGMKLVFNLPHMLRLKAMMQPWEAEVTGADQTRMVKCADRWGY-DMI
TH_2945|M.thermoresistible__bu -----MKFTFALPHMMELDAMMQPWEMAVTGADQTRMARRAEELGF-DMI
MAV_2659|M.avium_104 -----MRFTVYLPNCMHVAAITQPWEHQLSGADIARVAQHAEQLGY-SMV
MMAR_1586|M.marinum_M -----MQLGLHA-LGIGAGADRSMIDAVACAADDAGFATLWAGEHV-VMV
MUL_3448|M.ulcerans_Agy99 -----MQLGLHA-LEIGAGADRSMIDAVACAADDAGFATLWAGEHV-VMV
MAB_0366|M.abscessus_ATCC_1997 -----MKIGVVAPVELGVTAEPDKILEFARAAERLGFSEISVVEHA-VVI
MLBr_00131|M.leprae_Br4923 --MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNALV
. . :
Mb3106c|M.bovis_AF2122/97 VNTQSPYPGGGPIPEKYY---RTLDPFVALAAAAATT--QSLVLGTGIAL
Rv3079c|M.tuberculosis_H37Rv VNTQSPYPGGGPIPEKYY---RTLDPFVALAAAAATT--QSLVLGTGIAL
Mflv_1590|M.gilvum_PYR-GCK AVPEHFVIPAEHVELSGP---HYLQSTVAQAYLAGAT--ERIRLNSCITV
Mvan_5167|M.vanbaalenii_PYR-1 AVPEHFVIPAEHVELSGP---HYLQSTVAQAYLAGAT--ERIRLNSCITV
MSMEG_0654|M.smegmatis_MC2_155 AVPEHFVIPNEHVELSGP---HYLQSTVAQAYIAGAT--ERIMLNSCITV
TH_2945|M.thermoresistible__bu AVPEHIVMPREHVDLSGG---HWLHSTIAQAYFAGAT--ERITLNSCVTI
MAV_2659|M.avium_104 FLPEHFLTPTAHLELSGD---HYFDATTAQAFVAGAT--STITVGSMVTI
MMAR_1586|M.marinum_M DRHTSRYPYSEDGVIAIPPQADWLDPMIALSFAAAAS--SRITVATGVLL
MUL_3448|M.ulcerans_Agy99 DRHTSRYPYSEDGVIAIPPQADWLDPMIALSFAAASS--SRITVATGVLL
MAB_0366|M.abscessus_ATCC_1997 GDTQSTYPYSPTGQSHLPDDIDIPDPLELLSFVAAAT--TTLGLSTGVLV
MLBr_00131|M.leprae_Br4923 PRSVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCVTD
.. . *. . : : :
Mb3106c|M.bovis_AF2122/97 IPERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGRV
Rv3079c|M.tuberculosis_H37Rv IPERDPIVTAKEVASLDLVSQGRFRFGVGVGWLREEVANHGVDPAVRGRV
Mflv_1590|M.gilvum_PYR-GCK LPLQHPIVLAKALATADWMSGGRMMVTFGVGWLKGEFDALGVPFRERGRI
Mvan_5167|M.vanbaalenii_PYR-1 LPLQHPVVLAKALATADWMSGGRMMVTFGVGWLQGEFEALGVPFRERGRM
MSMEG_0654|M.smegmatis_MC2_155 LPLQHPIVLAKALATADWMSSGRMMVTFGVGWLQREFELLGVPFHERGRM
TH_2945|M.thermoresistible__bu LPLQHPLVTAKALATADWLSGGRMMVTFGVGWLQREFELLGVPFRKRGRI
MAV_2659|M.avium_104 LPLHNPIIAAKQIATFDWLSGGRAQTTVGVGWLKEEYDAIGVPFTKRGRM
MMAR_1586|M.marinum_M LPEHNPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRAGR
MUL_3448|M.ulcerans_Agy99 LPEHNPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRVGR
MAB_0366|M.abscessus_ATCC_1997 LPDHHPVVLAKRLATLDRLSRGRLRICAGVGWMREEIEACGGDFDRRGRA
MLBr_00131|M.leprae_Br4923 AGRRNPAVTAQAAATLHLLTRGKAMLGIGVGE-REGNEPYGVEWTKPVAR
:.* : *: *: . :: *: *** : *
Mb3106c|M.bovis_AF2122/97 IDERLRAIIEIWTQE--QAEFHGTYVDFDPIYCWPKPVTKPYPPLYVGGG
Rv3079c|M.tuberculosis_H37Rv IDERLRAIIEIWTQE--QAEFHGTYVDFDPIYCWPKPVTKPYPPLYVGGG
Mflv_1590|M.gilvum_PYR-GCK ADEYLAAIVELWTSD--SPSFDGRYVSFDEIAFEPKPVQRPHLPIWIGGD
Mvan_5167|M.vanbaalenii_PYR-1 ADEYLAVIKELWTSD--APSFEGKYVSFREVAFEPKPVQKPHLPIWIGGD
MSMEG_0654|M.smegmatis_MC2_155 ADEYLAAIVELWTSD--SPKFEGRYVSFGDIAFEPKPVQKPHLPIFIGGD
TH_2945|M.thermoresistible__bu ADEYLAAIIELWTQD--EPSFAGQFVSFEDVVFEPKPIQQPHPPIWIGGD
MAV_2659|M.avium_104 ADEYLEAMFELWHSD--SPSYDGEFVKFDDVAFGPKPISTPHPTVWMGGD
MMAR_1586|M.marinum_M TAEYVAAMRTLWRDD--LASFTGEFVRFDSVRVNPKPVRDRRVPVMVGGN
MUL_3448|M.ulcerans_Agy99 TAEYVAAMRTLWRDD--LASFTGEFVRFDSVRVNPKPVRDRRVPVMVGGN
MAB_0366|M.abscessus_ATCC_1997 ADEAIAVMRALWSTDG-PTSHDGEFYSFRNAYSYPKPVRPQGVPLYIGGH
MLBr_00131|M.leprae_Br4923 FQEALATIRALWDSNGELVSRESQFFPLHNALFDLPPYRGKWPEIWVAAH
* : .: :* : . . : : * : :..
Mb3106c|M.bovis_AF2122/97 P-ANFPRIARLNAGWIAI-SPSPQRLSGPLQRLRAMAG------------
Rv3079c|M.tuberculosis_H37Rv P-ANFPRIARLNAGWIAI-SPSPQRLSGPLQRLRAMAG------------
Mflv_1590|M.gilvum_PYR-GCK ADAALRRAAKYASGWWSF-LTPPDKIAERVEFIKSQDGYDGRPFDVVHGL
Mvan_5167|M.vanbaalenii_PYR-1 ADAALRRAAKYASGWWSF-LTPPEKLAERLDFIKSQPDYDGRPFDVVHGL
MSMEG_0654|M.smegmatis_MC2_155 ADAALRRAARYASGWWSF-LTPPEKLAERIDFIKSQPEYDGRAFDVVHGM
TH_2945|M.thermoresistible__bu SDAALRRAARFASGWFTF-LTKPEDIAARVDIITSQPEYDGRPFDVMHGL
MAV_2659|M.avium_104 ADAVLRRAARFGDGWAPW-LTKPDELPAKLDYLRSQPGFDDRPFSVFYSL
MMAR_1586|M.marinum_M SDAALRRVAAWADGWYGFNLDGVGAVRERVGTLDRLCAESGR------NR
MUL_3448|M.ulcerans_Agy99 SDAALRRVAAWADGWYGFNLDGVGAVRERVGTLDRLCAESGR------NR
MAB_0366|M.abscessus_ATCC_1997 SKAAARRAGRLGSGFQPLGLVGD-DLTAAVGVMRAAAVDAGR------DP
MLBr_00131|M.leprae_Br4923 GPRMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDPMSITPA
. .: : :
Mb3106c|M.bovis_AF2122/97 --------------------------------------GDVPVTVCQWG-
Rv3079c|M.tuberculosis_H37Rv --------------------------------------GDVPVTVCQWG-
Mflv_1590|M.gilvum_PYR-GCK GTN-----------------------------RVGEGHVAQKDPHARPG-
Mvan_5167|M.vanbaalenii_PYR-1 GTN-----------------------------RVGEGHVAQHDPDARPG-
MSMEG_0654|M.smegmatis_MC2_155 ATT-----------------------------RVGEGHTVRDDPNARPG-
TH_2945|M.thermoresistible__bu GTN-----------------------------RVGEGHVPTGDRGAWPG-
MAV_2659|M.avium_104 AVL-----------------------------SVGQEHAIVDDPNAQFG-
MMAR_1586|M.marinum_M D-------------------------------ELRLSVALRCPQPCDVD-
MUL_3448|M.ulcerans_Agy99 D-------------------------------ELRLSVALRCPQPCDVD-
MAB_0366|M.abscessus_ATCC_1997 RGL-----------------------------DLVLGHGLHRVDQAALD-
MLBr_00131|M.leprae_Br4923 AVRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHPMGADFAG
.
Mb3106c|M.bovis_AF2122/97 -----------EAAAKDLEGYRHLG-VERVLLELPTEPRDPTLRYLDKLQ
Rv3079c|M.tuberculosis_H37Rv -----------EAAAKDLEGYRHLG-VERVLLELPTEPRDPTLRYLDKLQ
Mflv_1590|M.gilvum_PYR-GCK -----------MSAAEIADKLNWLGEQGVTVSAVPIPKVSGVEEYLDYAQ
Mvan_5167|M.vanbaalenii_PYR-1 -----------MSAAEIVDRLSWLGAQGVTVSAVPIPKVRGVEEYLDYAQ
MSMEG_0654|M.smegmatis_MC2_155 -----------MSAQEIIDRLSWLGEQGVTVSAVPLPPVRGVDEYLDYAQ
TH_2945|M.thermoresistible__bu -----------MSAAELIDRIGALHEHGVTYTSVPIPPVRGVEEYLDYSQ
MAV_2659|M.avium_104 -----------QSAQQVIDNCNMLAERGVTDTWVNPPALDGLSAYLDHMQ
MMAR_1586|M.marinum_M -----------ALAELGIDELVLVETPPEAADAAQNWVSALAERWLSTVW
MUL_3448|M.ulcerans_Agy99 -----------ALAELGIDELVLVETPPEAADAAQNWVSALAERWLSTVW
MAB_0366|M.abscessus_ATCC_1997 -----------QAAHAGAGRMLLSASRRATTLEAVLEEMAGCATRLELGG
MLBr_00131|M.leprae_Br4923 VQDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVAEWRDHGL
. .
Mb3106c|M.bovis_AF2122/97 AELARLA----------------------------
Rv3079c|M.tuberculosis_H37Rv AELARLA----------------------------
Mflv_1590|M.gilvum_PYR-GCK WVIEEIRPQVR------------------------
Mvan_5167|M.vanbaalenii_PYR-1 WVIEEIKPQVP------------------------
MSMEG_0654|M.smegmatis_MC2_155 WVIEEIKPQVP------------------------
TH_2945|M.thermoresistible__bu WVMEEIAPNVP------------------------
MAV_2659|M.avium_104 WVAEEIIPKVG------------------------
MMAR_1586|M.marinum_M VR---------------------------------
MUL_3448|M.ulcerans_Agy99 VR---------------------------------
MAB_0366|M.abscessus_ATCC_1997 PR---------------------------------
MLBr_00131|M.leprae_Br4923 KYLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL