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STPVVVQTPAMASPWEGGADIEDVARIAEVADSLGFDYLTCSEHVAVPVDEAGLRGAVYWDPLATLGFLA ARTSRIRLATSVLVLGYHHPLEIAKRYGTLDRVSGGRLVLGVGVGSLRAEFEMLSAPWEDRGVRADDAIR ALRSSLSVSAPSYHGEFHRYQAMMVEPHAVQPRVPIWVGGRTARSLRRAVGLADGWMPFGLTPARIAEML AAVDIPDDFDIVLAVGPLDPRARDECLNRLRALRDVGATAVTCSLSASSAEHYCDQLASLRDLVDEL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_3368 | - | - | 100% (278) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_5167 | - | 1e-39 | 36.53% (219) | luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_2248 | - | 2e-25 | 34.39% (189) | luciferase family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0965c | - | 2e-19 | 29.65% (199) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_4544 | - | 1e-128 | 79.86% (278) | luciferase family protein |
| M. tuberculosis H37Rv | Rv0940c | - | 2e-19 | 29.65% (199) | oxidoreductase |
| M. leprae Br4923 | MLBr_00348 | - | 4e-11 | 28.14% (199) | putative coenzyme F420-dependent oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 2e-29 | 33.94% (274) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_3440 | - | 8e-88 | 57.97% (276) | hypothetical protein MMAR_3440 |
| M. avium 104 | MAV_3045 | - | 8e-36 | 34.93% (209) | hypothetical protein MAV_3045 |
| M. smegmatis MC2 155 | MSMEG_2896 | - | 7e-93 | 60.87% (276) | hypothetical protein MSMEG_2896 |
| M. thermoresistible (build 8) | TH_3565 | - | 1e-102 | 64.73% (275) | PUTATIVE luciferase family protein |
| M. ulcerans Agy99 | MUL_2716 | - | 1e-86 | 57.25% (276) | hypothetical protein MUL_2716 |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0965c|M.bovis_AF2122/97 -------------MRFSYAEAMTDFTFYIPLAKAAEAAGYSSMTIP-DSI
Rv0940c|M.tuberculosis_H37Rv -------------MRFSYAEAMTDFTFYIPLAKAAEAAGYSSMTIP-DSI
Mvan_3368|M.vanbaalenii_PYR-1 ---------------MSTPVVVQTPAMASPWEGGADIEDVARIAEVADSL
Mflv_4544|M.gilvum_PYR-GCK -----------MRIGLSTPVVVQTPAAASPWEAGAGIGDIARIAETADDL
TH_3565|M.thermoresistible__bu -----------MRIGISTPVVMQMPGVASDWERTAGPDELARVAAAADDL
MSMEG_2896|M.smegmatis_MC2_155 -------------MGLSTPVVVQVPQVASAWEATATVDDLVAIAQAADET
MMAR_3440|M.marinum_M ------MSAAAAKLSIATPVVTLLPGVSAPWEKTASIEDLTQIAETADKL
MUL_2716|M.ulcerans_Agy99 MLASIAMSAAAAKLSIATPVVTLLPGVSAPWEKTASIEDLTQIAETADKL
MAB_0366|M.abscessus_ATCC_1997 -----------MKIGVVAPVELGVTAEPDKILEFARAAERLGFSEISVVE
MAV_3045|M.avium_104 -----------MKFAFPVPHLMRLKAIAQPWEAAVTGPEQRRMMQCADRW
MLBr_00348|M.leprae_Br4923 ---------------MVERANAMKLGLQLGYWAAQPPGNAAELVAAAEGA
. .
Mb0965c|M.bovis_AF2122/97 AYPFE--SDSKYPYTPDGNREFMDGKPFIETFVLTAALGAVTTRLRFNFF
Rv0940c|M.tuberculosis_H37Rv AYPFE--SDSKYPYTPDGNREFMDGKPFIETFVLTAALGAVTTRLRFNFF
Mvan_3368|M.vanbaalenii_PYR-1 GFDYL--TCSEHVAVPVDEAGLR-GAVYWDPLATLGFLAARTSRIRLATS
Mflv_4544|M.gilvum_PYR-GCK GFDYL--TCSEHVAVPVGDAAVR-GATYWDPLATLGFLAARTARIRLATS
TH_3565|M.thermoresistible__bu GFEFL--TCAEHVVVPEADAAVR-GATYWDPVATLGFLAAHTTRIRLATS
MSMEG_2896|M.smegmatis_MC2_155 GFDFL--TCSEHVAIPRADAARR-GAVYWDPLSTLGFLAAHTRRIRLATA
MMAR_3440|M.marinum_M GYYHL--TCSEHIALPAAEKRRR-GTRYWDPLATLGYLAARTQRIRLATN
MUL_2716|M.ulcerans_Agy99 GYYHL--TCSEHIALPAAEKRRR-GTRYWDPLATLSYLAARTQRIRLATN
MAB_0366|M.abscessus_ATCC_1997 HAVVIGDTQSTYPYSPTGQSHLPDDIDIPDPLELLSFVAAATTTLGLSTG
MAV_3045|M.avium_104 GYDMI--AVPEHLVIPVDQVELS-GSHYLHSTTAQAFIAGATERVAINSC
MLBr_00348|M.leprae_Br4923 GFDAV----------FTGEAWGS------DAYTPLAWWGSSTQRVRLGTS
: .. . .. * : :
Mb0965c|M.bovis_AF2122/97 VLKLPIRPPALVAKQAGSLAALIGNRVGLGVGTSPWPEDYELMGVPFAKR
Rv0940c|M.tuberculosis_H37Rv VLKLPIRPPALVAKQAGSLAALIGNRVGLGVGTSPWPEDYELMGVPFAKR
Mvan_3368|M.vanbaalenii_PYR-1 VLVLGYHHPLEIAKRYGTLDRVSGGRLVLGVGVGSLRAEFEMLSAPWEDR
Mflv_4544|M.gilvum_PYR-GCK VLVLGYHHPLEIAKRYGTLDRVSGGRLILGVGVGSLQPEFDLLGAPWEER
TH_3565|M.thermoresistible__bu VIVLGYHHPLEVAKRYGTVDRLSGGRVILGVGVGSLKAEFDLLDAAWSDR
MSMEG_2896|M.smegmatis_MC2_155 VLVLSYHHPLELVKRYGTLDRLSCGRLVLGVGIGSLREEFDLIGAPWEKR
MMAR_3440|M.marinum_M VLVLGYHHPLEIAKRYGTLDTVSNGRLILGVGVGSLKEEFDLIGAPFEDR
MUL_2716|M.ulcerans_Agy99 VLVLGYHHPLEIAKRYGTLDTVSNGRLILGVGVGSLKEEFDLIGAPFENR
MAB_0366|M.abscessus_ATCC_1997 VLVLPDHHPVVLAKRLATLDRLSRGRLRICAGVGWMREEIEACGGDFDRR
MAV_3045|M.avium_104 VTILPLQHPIVLAKALATADWMSGGRMMVTFGVGWLAREFELLGVPFGER
MLBr_00348|M.leprae_Br4923 VVQLSARTPTACAMAALTLDHLSGGRHILGLGVSGPQVVEGWYGQPFPKP
* * : * . : : .* : * . . :
Mb0965c|M.bovis_AF2122/97 GKRIDECIEIVRGLTTGDYFE-FHGEFYDIPKTKMTPAPTQP--------
Rv0940c|M.tuberculosis_H37Rv GKRIDECIEIVRGLTTGDYFE-FHGEFYDIPKTKMTPAPTQP--------
Mvan_3368|M.vanbaalenii_PYR-1 GVRADDAIRALRSSLSVSAPS-YHGEFHRYQAMMVEPHAVQPR-------
Mflv_4544|M.gilvum_PYR-GCK GARADDAIRALRSSLSVAEPS-YDGDFYTFGGMVVEPHAEQPR-------
TH_3565|M.thermoresistible__bu DARADEAIRALRASLSQSRPH-HDGEHYRYSGFIVEPCAVQDR-------
MSMEG_2896|M.smegmatis_MC2_155 GARADDAIRALRASMGRAEPA-YEGPFYAFSEMTVLPHAERID-------
MMAR_3440|M.marinum_M GARADDALRALRAALSVPEPR-YHGEFYSFRDMVVDPCAVQKR-------
MUL_2716|M.ulcerans_Agy99 GARADDALRALRAALSVPEPR-YHGEFYSFRDMVVDPCAVQKR-------
MAB_0366|M.abscessus_ATCC_1997 GRAADEAIAVMRALWSTDGPTSHDGEFYSFRNAYSYPKPVRPQG------
MAV_3045|M.avium_104 GRIADEYLAAIDELWTSDTPR-FDGRYVSFADIAFEPKPVQKPH------
MLBr_00348|M.leprae_Br4923 LSRTREYIDIVRQVWAREAPVVSDGQHYPLPLTGAGATGLGKALKPITHP
: : : .* . .
Mb0965c|M.bovis_AF2122/97 ----IPILVGGHADAALRRAAR-ADGWMHGGGDPDELDRLIARVKRLR-E
Rv0940c|M.tuberculosis_H37Rv ----IPILVGGHADAALRRAAR-ADGWMHGGGDPDELDRLIARVKRLR-E
Mvan_3368|M.vanbaalenii_PYR-1 ----VPIWVGGRTARSLRRAVGLADGWMPFGLTPARIAEMLAAVDIPDDF
Mflv_4544|M.gilvum_PYR-GCK ----VPIWVGGRSRRSLRRAVGLADGWMPFGLRTMQIADMLATVDIPDGF
TH_3565|M.thermoresistible__bu ----VPIWVGGRTRRSLRRAVTLGDGWMPFGISAAQISEWLGSVELPDGF
MSMEG_2896|M.smegmatis_MC2_155 ----VPIWVGGRTEASLRRAVSLGDGWMPFGLRTSGIRALLDATPTPDGF
MMAR_3440|M.marinum_M ----LPIWVGGRTLRSLRRATSLAEGWVPFGISLGEARDWLSRFDIGSGF
MUL_2716|M.ulcerans_Agy99 ----LPIWVGGRTLRSLRRATSLAEGWVPFGISLGEARDWLSRFDIGSGF
MAB_0366|M.abscessus_ATCC_1997 ----VPLYIGGHSKAAARRAGRLGSGFQPLGLVGDDLTAAVGVMRAAAVD
MAV_3045|M.avium_104 ----LPVWIGGDADAALRRAARFGSGWWPFLTPPEQIAEKLDYIKSQPCY
MLBr_00348|M.leprae_Br4923 LRADIPIMLGAEGPKNVALAAEICDGWLPIFFSPRMADMYNEWLDEGFAR
:*: :*. * .*:
Mb0965c|M.bovis_AF2122/97 EAG--------KTSPFEIHVISLDGFTVDGVKR---------------LE
Rv0940c|M.tuberculosis_H37Rv EAG--------KTSPFEIHVISLDGFTVDGVKR---------------LE
Mvan_3368|M.vanbaalenii_PYR-1 DIV--------LAVG-PLDPR-ARDECLNRLRA---------------LR
Mflv_4544|M.gilvum_PYR-GCK DIV--------LPAG-PLDPR-EPSGCLTRLRA---------------LR
TH_3565|M.thermoresistible__bu EVV--------LATS-ALDPLGDPDAARRRLDR---------------LR
MSMEG_2896|M.smegmatis_MC2_155 EVV--------LSTGHAVDPIGDPAGTRKRLSG---------------LA
MMAR_3440|M.marinum_M EVV--------LSSPEPLNPIGDPERTRHLLAD---------------LA
MUL_2716|M.ulcerans_Agy99 EVV--------LSSPEPLNPIGDPERTRHLLAD---------------LA
MAB_0366|M.abscessus_ATCC_1997 AGR--------DPRG--LDLVLGHGLHRVDQAA---------------LD
MAV_3045|M.avium_104 DGRP-----FEVMHGLGTNRVGEGHVARRDVRDRPGMSAGQIVDRLGWLA
MLBr_00348|M.leprae_Br4923 TGARRSREDFEICASAQIVVTEDRAAAFAGIKP------------FLALY
*
Mb0965c|M.bovis_AF2122/97 DKGVTDVIVGFRVPYTMGPDTEPLQTKIRNLEMFAENVIAKV--------
Rv0940c|M.tuberculosis_H37Rv DKGVTDVIVGFRVPYTMGPDTEPLQTKIRNLEMFAENVIAKV--------
Mvan_3368|M.vanbaalenii_PYR-1 DVGATAVTCSLSAS-----SAEHYCDQLASLRDLV--DEL----------
Mflv_4544|M.gilvum_PYR-GCK DVGATAVTCSVAAD-----STDHYCAQLASLRGIV--DEL----------
TH_3565|M.thermoresistible__bu ELGATAVTATVSAT-----SAAHYCEQLAALRDLAMGDAL----------
MSMEG_2896|M.smegmatis_MC2_155 DAGATVASCTISAS-----SAAHYRDQVARLSEIAGTVEGRGA-------
MMAR_3440|M.marinum_M AHGATTICATFAHS-----SRQQYLDNLHALAELDSP-------------
MUL_2716|M.ulcerans_Agy99 AHGATTICATFAHS-----SRQQYLDNLHALAELDSP-------------
MAB_0366|M.abscessus_ATCC_1997 QAAHAGAGRMLLSASRRATTLEAVLEEMAGCATRLELGGPR---------
MAV_3045|M.avium_104 EQGVTVTAVPVPAVG----GVDEYLDYAQWVIEEIKPQLA----------
MLBr_00348|M.leprae_Br4923 MGGMGAEGTNFHADVYRRMGYAEVVDEVTALFRSNQKDKAAEIIPNELVD
. .
Mb0965c|M.bovis_AF2122/97 -------------------------------------------
Rv0940c|M.tuberculosis_H37Rv -------------------------------------------
Mvan_3368|M.vanbaalenii_PYR-1 -------------------------------------------
Mflv_4544|M.gilvum_PYR-GCK -------------------------------------------
TH_3565|M.thermoresistible__bu -------------------------------------------
MSMEG_2896|M.smegmatis_MC2_155 -------------------------------------------
MMAR_3440|M.marinum_M -------------------------------------------
MUL_2716|M.ulcerans_Agy99 -------------------------------------------
MAB_0366|M.abscessus_ATCC_1997 -------------------------------------------
MAV_3045|M.avium_104 -------------------------------------------
MLBr_00348|M.leprae_Br4923 STMIVGDVDYVCKQIAAWSAAGVTMMMVSASSVEQVRDLAGLF