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QLGLHALEIGAGADRSMIDAVACAADDAGFATLWAGEHVVMVDRHTSRYPYSEDGVIAIPPQADWLDPMI ALSFAAASSSRITVATGVLLLPEHNPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRVGR TAEYVAAMRTLWRDDLASFTGEFVRFDSVRVNPKPVRDRRVPVMVGGNSDAALRRVAAWADGWYGFNLDG VGAVRERVGTLDRLCAESGRNRDELRLSVALRCPQPCDVDALAELGIDELVLVETPPEAADAAQNWVSAL AERWLSTVWVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_3448 | - | - | 100% (292) | oxidoreductase |
| M. ulcerans Agy99 | MUL_4083 | - | 3e-32 | 31.30% (246) | oxidoreductase |
| M. ulcerans Agy99 | MUL_1043 | - | 7e-31 | 35.86% (237) | hypothetical protein MUL_1043 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3099c | - | 1e-48 | 83.64% (110) | hypothetical protein Mb3099c |
| M. gilvum PYR-GCK | Mflv_4839 | - | 4e-88 | 60.22% (269) | luciferase family protein |
| M. tuberculosis H37Rv | Rv3072c | - | 1e-48 | 83.64% (110) | hypothetical protein Rv3072c |
| M. leprae Br4923 | MLBr_00131 | - | 6e-11 | 27.22% (180) | putative oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0366 | - | 2e-40 | 39.55% (268) | hypothetical protein MAB_0366 |
| M. marinum M | MMAR_1586 | - | 1e-167 | 98.97% (292) | oxidoreductase |
| M. avium 104 | MAV_2935 | - | 4e-47 | 39.50% (281) | hypothetical protein MAV_2935 |
| M. smegmatis MC2 155 | MSMEG_2811 | - | 1e-111 | 66.78% (289) | hydride transferase 1 |
| M. thermoresistible (build 8) | TH_2830 | - | 4e-35 | 35.42% (271) | PUTATIVE luciferase family protein |
| M. vanbaalenii PYR-1 | Mvan_4864 | - | 1e-32 | 34.60% (263) | luciferase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_3448|M.ulcerans_Agy99 --------MQLGLHALEIGAGADRSMIDAVACAADDAGFATLWAGEHVVM
MMAR_1586|M.marinum_M --------MQLGLHALGIGAGADRSMIDAVACAADDAGFATLWAGEHVVM
Mb3099c|M.bovis_AF2122/97 MACVRRSCDVTGTARAGIGAGADPAVVDAVAVAADDCGFATLWVGEHVVM
Rv3072c|M.tuberculosis_H37Rv MACVRRSCDVTGTARAGIGAGADPAVVDAVAVAADDCGFATLWVGEHVVM
MSMEG_2811|M.smegmatis_MC2_155 --------MQISLHALGIGAGARREIIDAVAVAAERAGFTTLWCGEHVVM
Mflv_4839|M.gilvum_PYR-GCK -------------------------MIDAVAASAERSGFETLWFGDQVVM
MAB_0366|M.abscessus_ATCC_1997 -------MKIGVVAPVELGVTAEPDKILEFARAAERLGFSEISVVEHAVV
MAV_2935|M.avium_104 ------------MAPVADGVTADPDWMVAFARHLEACGFESIVAVEHTVL
TH_2830|M.thermoresistible__bu -----------MDFGLVLFTSDRGITPAKAATLADDHGFTTFYVPEHTHI
Mvan_4864|M.vanbaalenii_PYR-1 -----------MNYGLVLFTSDRGITPAAAAKLADEHGFETFYVPEHTHI
MLBr_00131|M.leprae_Br4923 ----MAGFRFGFVDALVHTLFPPSLPARASIVSGAVLGADSYWVGDHLNA
* ::
MUL_3448|M.ulcerans_Agy99 VDRHTSRYP-YSEDGVIAIPPQADWLDPMIALSFAAASSSRITVATGVLL
MMAR_1586|M.marinum_M VDRHTSRYP-YSEDGVIAIPPQADWLDPMIALSFAAAASSRITVATGVLL
Mb3099c|M.bovis_AF2122/97 VDRPASRYP-YSRDGVIAVPAQADWLDPMIALSFAAAASSRVDVATGVLL
Rv3072c|M.tuberculosis_H37Rv VDRPASRYP-YSRDGVIAVPAQADWLDPMIALSFAAAASSRVDVATGVLL
MSMEG_2811|M.smegmatis_MC2_155 VDRPRSRYP-YSADGRIAVAADADWLDPMIALSFAAAATSTIRIATGVLL
Mflv_4839|M.gilvum_PYR-GCK ADEDGPHHP-YRDDGEIPASAQTDWLDPLIALSFAAAATNRIELATGVLV
MAB_0366|M.abscessus_ATCC_1997 IGDTQSTYP-YSPTGQSHLPDDIDIPDPLELLSFVAAATTTLGLSTGVLV
MAV_2935|M.avium_104 LTRYDSVYP-YDSSGRVGLAPDCPIPDPLDLLAFLAGHTTRLGLATGVLV
TH_2830|M.thermoresistible__bu PVKREAAHP-TTGDSSLPDDRYMRTLDPWVSLATASAVTSRVRLSTAVAL
Mvan_4864|M.vanbaalenii_PYR-1 PIKRQAAHP-TTGDESLPDDRYMRTLDPWVSLGTAAAVTSRVRLSTAVAL
MLBr_00131|M.leprae_Br4923 LVPRSVATPKYLGVAAKVVPKIDANYEPWTMLGNLAAGNRLNGLRLGVCV
* :* *. :. . : .* :
MUL_3448|M.ulcerans_Agy99 LPE--HNPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRV
MMAR_1586|M.marinum_M LPE--HNPVVVAKQAASLDRLSGGRLTLGVGVGWSREEFAALGVPFQDRA
Mb3099c|M.bovis_AF2122/97 LPE--HNPVIVAKEAASLDRLSGRRLTLGVAS------------------
Rv3072c|M.tuberculosis_H37Rv LPE--HNPVIVAKEAASLDRLSGRRLTLGVAS------------------
MSMEG_2811|M.smegmatis_MC2_155 LPE--HNPVIMAKQAASVDQLSGGRLLLGVGIGWSREEFEALGVPFARRG
Mflv_4839|M.gilvum_PYR-GCK LPE--RNPVVTAKQAASLDRMTGGRLTLGVGIGISPQEYDALGVPFASRG
MAB_0366|M.abscessus_ATCC_1997 LPD--HHPVVLAKRLATLDRLSRGRLRICAGVGWMREEIEACGGDFDRRG
MAV_2935|M.avium_104 LPN--HHPVVLAKRVGTLDALSGGRLRLCVGVGWLQEELRACGADFDNRG
TH_2830|M.thermoresistible__bu PVE--HDPISLAKTIASLDHLSGGRVSLGVGFGWNTDELVDHGVPPKRRR
Mvan_4864|M.vanbaalenii_PYR-1 PVE--HDPITLAKSIATLDHLSGGRVSLGVGFGWNTDELADHNVPPGRRR
MLBr_00131|M.leprae_Br4923 TDAGRRNPAVTAQAAATLHLLTRGKAMLGIGVG-EREGNEPYGVEWTKPV
:.* *: .::. :: : : .
MUL_3448|M.ulcerans_Agy99 GRTAEYVAAMRTLWRD---DLASFTGEFVRFDSVRVNPKPVRDRRVPVMV
MMAR_1586|M.marinum_M GRTAEYVAAMRTLWRD---DLASFTGEFVRFDSVRVNPKPVRDRRVPVMV
Mb3099c|M.bovis_AF2122/97 --------------------------------------------------
Rv3072c|M.tuberculosis_H37Rv --------------------------------------------------
MSMEG_2811|M.smegmatis_MC2_155 ARTAEYVEAMRTLWRQ---DVADFTGEFAAFDAVRLHPKPSAG-SIPIIV
Mflv_4839|M.gilvum_PYR-GCK ARLAEYVGAMRTLWRD---DDASFAGRYVAFDGVRANPKPQGR-SIPVVL
MAB_0366|M.abscessus_ATCC_1997 RAADEAIAVMRALWST--DGPTSHDGEFYSFRNAYSYPKPVRPQGVPLYI
MAV_2935|M.avium_104 RRADEQLAVLRALWAHRPDG-ASFHGEFFTFDNVMCYPKPVAAERFPVHI
TH_2830|M.thermoresistible__bu TMLREYLEAMRALWTQ---EEASYQGEFVSFGPSWAWPKPVQAHIPVLVG
Mvan_4864|M.vanbaalenii_PYR-1 TMLREYLEAMRALWTQ---EEAEFDGEFVKFGPSWAWPKPVQAHIPVLVG
MLBr_00131|M.leprae_Br4923 ARFQEALATIRALWDSN-GELVSRESQFFPLHNALFDLPPYRGKWPEIWV
MUL_3448|M.ulcerans_Agy99 GGNSDAALRRVAAWADGWYGFNLDGVGAVRERVGTLDRLCAESGRNRDEL
MMAR_1586|M.marinum_M GGNSDAALRRVAAWADGWYGFNLDGVGAVRERVGTLDRLCAESGRNRDEL
Mb3099c|M.bovis_AF2122/97 -----------------------DGP-----RRSSTRSECHSSGAQS---
Rv3072c|M.tuberculosis_H37Rv -----------------------DGP-----RRSSTRSECHSSGAQS---
MSMEG_2811|M.smegmatis_MC2_155 GGNGDRALARVASWGDGWYGFNLDGVAAVGERMDMLRRLCARAGRDVDDL
Mflv_4839|M.gilvum_PYR-GCK GGNSDAALRRVAEWGDGWYGFDLADVEEAAFRASKLRSMCREFGRDPTEL
MAB_0366|M.abscessus_ATCC_1997 GGHSKAAARRAGRLGSGFQPLGLVGDD-LTAAVGVMRAAAVDAGRDPRGL
MAV_2935|M.avium_104 GGHSRAAARRAGRFGDGFQPLGVTGAR-LASLIGLMRDEAVAAGRDPAAL
TH_2830|M.thermoresistible__bu AAGTEKNFKWIARSADGWITTPRDVD--IEEPVKLLQDIWADAGRDGAPQ
Mvan_4864|M.vanbaalenii_PYR-1 AAGTEKNFKWIAKSADGWITTPRDFT--IDEPVKLLQDTWAAAGRDGAPQ
MLBr_00131|M.leprae_Br4923 AAHGPRMLQATGRYADAWIPIVLVRPTDYSCALEVVRTAASDAGRDPMSI
* :
MUL_3448|M.ulcerans_Agy99 RLSV--ALRCPQPCDVDALAELGIDELVLVETPPEAADAAQNWVSALAER
MMAR_1586|M.marinum_M RLSV--ALRCPQPCDVDALAELGIDELVLVETPPEAADAAQNWVSALAER
Mb3099c|M.bovis_AF2122/97 -------------------------------APPNTSLQCAHYGATTSHR
Rv3072c|M.tuberculosis_H37Rv -------------------------------APPNTSLQCAHYGATTSHR
MSMEG_2811|M.smegmatis_MC2_155 HCAV--ALQAPAVGDIPALVDLGVDELVIVESPPQDPDVAADWVDALADR
Mflv_4839|M.gilvum_PYR-GCK KLSV--ALHDPVPADAVRLADAGIDELVLVAGPPADPIAAEAWIADLAGQ
MAB_0366|M.abscessus_ATCC_1997 DLVLGHGLHRVDQAALDQAAHAGAGRMLLSASRRATTLEAVLEEMAGCAT
MAV_2935|M.avium_104 EVSLGHSVSKIDAERAARLADQGADRLVLAMPP-TSDIEQAKDMLSACAQ
TH_2830|M.thermoresistible__bu IVALD---FKPDPDKLARWRDLGVTEVLFGLPDRSDDEIAAYVERLAGKL
Mvan_4864|M.vanbaalenii_PYR-1 IVALD---FKPDPEKLAHWREIGVTEVLFGLPDKSEADVAAYVERLAGKL
MLBr_00131|M.leprae_Br4923 TPAAVRGIITGRTRDDVDEALDSVLVRMIALGVPGEAWARHGVEHPMGAD
MUL_3448|M.ulcerans_Agy99 WLSTVWVR------------------------------------------
MMAR_1586|M.marinum_M WLSTVWVR------------------------------------------
Mb3099c|M.bovis_AF2122/97 STATVGS-------------------------------------------
Rv3072c|M.tuberculosis_H37Rv STATVGS-------------------------------------------
MSMEG_2811|M.smegmatis_MC2_155 WITCI---------------------------------------------
Mflv_4839|M.gilvum_PYR-GCK WMRVRT--------------------------------------------
MAB_0366|M.abscessus_ATCC_1997 RLELG---GPR---------------------------------------
MAV_2935|M.avium_104 RLSLRPVSGP----------------------------------------
TH_2830|M.thermoresistible__bu GLS-----------------------------------------------
Mvan_4864|M.vanbaalenii_PYR-1 GALT----------------------------------------------
MLBr_00131|M.leprae_Br4923 FAGVQDIIPQTIDEETVVSYAAKVPAALMKEVLFSGTPEEVIDQVAEWRD
MUL_3448|M.ulcerans_Agy99 --------------------------------------
MMAR_1586|M.marinum_M --------------------------------------
Mb3099c|M.bovis_AF2122/97 --------------------------------------
Rv3072c|M.tuberculosis_H37Rv --------------------------------------
MSMEG_2811|M.smegmatis_MC2_155 --------------------------------------
Mflv_4839|M.gilvum_PYR-GCK --------------------------------------
MAB_0366|M.abscessus_ATCC_1997 --------------------------------------
MAV_2935|M.avium_104 --------------------------------------
TH_2830|M.thermoresistible__bu --------------------------------------
Mvan_4864|M.vanbaalenii_PYR-1 --------------------------------------
MLBr_00131|M.leprae_Br4923 HGLKYLVVINGSLVNSSLRKTVSALLPHARVLRGLKKL