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VKSIFITGAGSGMGREGAKLFHAKGWRVGAVDRNDDGLATLQQELGDDRLWTRAVDVTDKAALDGALADF CAGNTGGGLDMMWNNAGIGESGWFEDVPYDAAMRVVDVNYKAVLTGAYGALPYLKKSAGSLMFSTSSSSA TYGMPRLAVYSSTKHAVKGLTEALSVEWQRHGVRVADVLPGLIDTAILTTTTNHSNDGAAPMTAEELRAT APKKGMLRLMPASSVAEVAWRAYNHPRRLHWYVPRSIRLIDVFKGLSPEFVRRSIVKSLPALMPKRQ
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2820 | - | - | 100% (277) | short chain dehydrogenase |
| M. avium 104 | MAV_2376 | - | 1e-24 | 38.02% (192) | short chain dehydrogenase |
| M. avium 104 | MAV_2098 | - | 1e-21 | 30.42% (263) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1914c | - | 1e-132 | 80.87% (277) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_0407 | - | 2e-37 | 42.33% (189) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv1882c | - | 1e-132 | 80.87% (277) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01094 | - | 9e-19 | 35.38% (195) | short chain alcohol dehydrogenase |
| M. abscessus ATCC 19977 | MAB_4335 | - | 8e-24 | 31.61% (193) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_2770 | - | 1e-124 | 79.26% (270) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_5053 | - | 4e-19 | 33.18% (217) | short chain alcohol dehydrogenase |
| M. thermoresistible (build 8) | TH_1963 | - | 1e-96 | 62.77% (282) | PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE |
| M. ulcerans Agy99 | MUL_2977 | - | 1e-124 | 79.26% (270) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0267 | - | 8e-37 | 35.40% (274) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_0407|M.gilvum_PYR-GCK -------MTKSVFITGAATGIGRATALLFAGRGYRVGGYDLDEDGLAVLA
Mvan_0267|M.vanbaalenii_PYR-1 -------MTKSVFITGAATGIGRATALLFAQRGYRVGGYDIDEAGLRLLA
Mb1914c|M.bovis_AF2122/97 --------MKAIFITGAGSGMGREGATLFHANGWRVGAIDRNEDGLAALR
Rv1882c|M.tuberculosis_H37Rv --------MKAIFITGAGSGMGREGATLFHANGWRVGAIDRNEDGLAALR
MAV_2820|M.avium_104 --------MKSIFITGAGSGMGREGAKLFHAKGWRVGAVDRNDDGLATLQ
MMAR_2770|M.marinum_M --------MKSVFITGAGSGMGREGAKLFHAKGWRVAAVDRDGAGLDALG
MUL_2977|M.ulcerans_Agy99 --------MKSGFVTGAGSGMGREGAKLFHAKGWRVAAVDRDGAGLDALG
TH_1963|M.thermoresistible__bu ---VTRQTARAVFITGAGSGMGRAGAELFHARGWRVGAVDRNAEGLSGLR
MLBr_01094|M.leprae_Br4923 ---MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQTE
MSMEG_5053|M.smegmatis_MC2_155 ---MEGFAGKVAVVTGAGSGIGQALAIELGRSGAKLAICDVDTEGLAATE
MAB_4335|M.abscessus_ATCC_1997 MGTAVQLAGKVVAVTGGARGIGRAIATAFAAEGAKVAIGDIDKKLCENTA
: :**.. *:*: * : * ::. * :
Mflv_0407|M.gilvum_PYR-GCK ADITAVGGTPVVAHLDVTDPDEVARRLAEFAEG-SGGRIDVLINNAGLLN
Mvan_0267|M.vanbaalenii_PYR-1 ADITAVGGRPVVGRLDVTDADEVAHRLAEFVDA-AGGRLDVLINNAGLLQ
Mb1914c|M.bovis_AF2122/97 VQLGAE--RLWARAVDVTDKAALEGALADFCAGNVGGGLDMMWNNAGIGE
Rv1882c|M.tuberculosis_H37Rv VQLGAE--RLWARAVDVTDKAALEGALADFCAGNVGGGLDMMWNNAGIGE
MAV_2820|M.avium_104 QELGDD--RLWTRAVDVTDKAALDGALADFCAGNTGGGLDMMWNNAGIGE
MMAR_2770|M.marinum_M AELGTE--RLWTRVVDVTDRDALDRALADFCAGTSHGGLDMMWNNAGIGE
MUL_2977|M.ulcerans_Agy99 AELGTE--RLWTRVVDVTDRDALDRALADFCAGTSHGGLDMMWNNAGIGE
TH_1963|M.thermoresistible__bu AQLGPE--RLFTGQVDVTDRSALEAGLARFCADNTGGGLDMMWNNAGIGA
MLBr_01094|M.leprae_Br4923 GQLKAIGASARTDRLDVTEREAFLTYADVVHEN--FGKVNQIYNNAGIAF
MSMEG_5053|M.smegmatis_MC2_155 ERLKAIGAPVKADRLDVTEREAFLLYADAVKEH--YGTVNQIYNNAGIAF
MAB_4335|M.abscessus_ATCC_1997 AEIGNS---AIGLPLDVTDHGSFEAFFDTIAAT--VGPVDVIVNNAGIMP
: :***: . . * :: : ****:
Mflv_0407|M.gilvum_PYR-GCK AGRFEEIPLEVHHREIEVNVKGVVNGLHAAFPYLKGTPGAVVVNLASASA
Mvan_0267|M.vanbaalenii_PYR-1 AGRFEDIPLPVHHRAIEVNVKGVVNGLHAAFPYLRDTPDAVVVNLSSASA
Mb1914c|M.bovis_AF2122/97 GGWFEDVPYEAAVRVVDVNFKAVLTGAYAALPYLKKAPGSLMFSTSSSSG
Rv1882c|M.tuberculosis_H37Rv GGWFEDVPYEAAVRVVDVNFKAVLTGAYAALPYLKKAPGSLMFSTSSSSG
MAV_2820|M.avium_104 SGWFEDVPYDAAMRVVDVNYKAVLTGAYGALPYLKKSAGSLMFSTSSSSA
MMAR_2770|M.marinum_M GGWFEDVPYDAAMRVVDVNFKAVLTGAYGALPYLRKAPGSLMFSTSSSSA
MUL_2977|M.ulcerans_Agy99 GGWFEDVPYDAAMRVVDVNFKAVLTGAYGALPYLRKAPGSLMFSTSSSSA
TH_1963|M.thermoresistible__bu SGWFEDVPHEAALRVVAINFTAVLTGAYAALPYLRRTPGSLMFSTSSSSA
MLBr_01094|M.leprae_Br4923 TGDVEVSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDGHVINISSVFG
MSMEG_5053|M.smegmatis_MC2_155 TGDVEISEFKDIERVMDVDYWGVVNGTKAFLPHLIASGDGHVINVSSVFG
MAB_4335|M.abscessus_ATCC_1997 ITPFDDESLESIQRQLDINVRGVMWGSQLAIKRMKPRGGGVIVNIASAAG
.: * : :: .*: * : : .. :.. :* .
Mflv_0407|M.gilvum_PYR-GCK IYGQAELANYSATKFFVRAITEALNLEWGHYG--IRVIDMWPLYVNTAMT
Mvan_0267|M.vanbaalenii_PYR-1 IYGQVELANYSATKFYVRAITEALNLEWAQHG--IRVIDMWPLYVNTAMT
Mb1914c|M.bovis_AF2122/97 TYGMPRIAVYSATKHAVKGLTEALSVEWQRHG--VRVADVLPGLIDTAIL
Rv1882c|M.tuberculosis_H37Rv TYGMPRIAVYSATKHAVKGLTEALSVEWQRHG--VRVADVLPGLIDTAIL
MAV_2820|M.avium_104 TYGMPRLAVYSSTKHAVKGLTEALSVEWQRHG--VRVADVLPGLIDTAIL
MMAR_2770|M.marinum_M TYGMPRLAVYSATKHAVKGLTEALSAEWRRHG--VRVADVLPGLIDTAIL
MUL_2977|M.ulcerans_Agy99 TYGMPRLAVYSATKHAVKGLTEALSAEWRRHG--VRVADVLPGLIDTAIL
TH_1963|M.thermoresistible__bu TYGMPQLAVYSATKHAVKGLTEALSVEWQRHG--VRVADIA---------
MLBr_01094|M.leprae_Br4923 LFSVPGQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIKTAIA
MSMEG_5053|M.smegmatis_MC2_155 LFSVPGQAAYNSAKFAVRGFTEALRQEMAIAKHPVKVTTVHPGGIKTAIA
MAB_4335|M.abscessus_ATCC_1997 KAGFPGLATYCATKHAVVGLSESLSLEYEPAG--ISVVCVMPGMVNTELI
. * * ::*. * .::*:* * : * :
Mflv_0407|M.gilvum_PYR-GCK KD----------------VKTGTTQSLGIRLTAQDIANDIVAAVDATWAR
Mvan_0267|M.vanbaalenii_PYR-1 QG----------------VKTGTTQSLGIRLTAQDIARDIVTAVEATWPR
Mb1914c|M.bovis_AF2122/97 TSTRQHSDEGPYTISAEQIRAAAPKKGMFRLMPSSSVAEAAWRAYQHPTR
Rv1882c|M.tuberculosis_H37Rv TSTRQHSDEGPYTISAEQIRAAAPKKGMFRLMPSSSVAEAAWRAYQHPTR
MAV_2820|M.avium_104 TTTTNHSNDGAAPMTAEELRATAPKKGMLRLMPASSVAEVAWRAYNHPRR
MMAR_2770|M.marinum_M TSTRQHSDASAPTLSSEQIRAAAPKKGMFRLLPASSVAEAAWQAYQHPTR
MUL_2977|M.ulcerans_Agy99 TSTRQHSDASAPTLSSEQIRAAAPKKGMFRLLPASSVAEAAWHAYQHPTR
TH_1963|M.thermoresistible__bu --------------------ARAPRRGMFRLLPPSSVAETAWAAYHDTGR
MLBr_01094|M.leprae_Br4923 RN----------ATAAEGLDVSKIASRFDTWVAHTSPQHAARIILKAVRK
MSMEG_5053|M.smegmatis_MC2_155 RN----------ATAAEGLDAKELAEAFDKKLANTTPQRAAVIILDGVRK
MAB_4335|M.abscessus_ATCC_1997 SG-------LDTHWLLKTVEPEDIANAVVKAVRRGVFPVFVPKMFGGMYR
. :
Mflv_0407|M.gilvum_PYR-GCK -----KALAQVHFPVGLQAKALALGARFSPAWLTRLVNKGLAGS------
Mvan_0267|M.vanbaalenii_PYR-1 -----RLVKQVHFPVGGQAKALALGSRFSPAWLTRLINKRLAGS------
Mb1914c|M.bovis_AF2122/97 ----------LHWYVPRSIRWIDRLKGVSPEFVRRHIAKSLATLEPKRK-
Rv1882c|M.tuberculosis_H37Rv ----------LHWYVPRSIRWIDRLKGVSPEFVRRHIAKSLATLEPKRK-
MAV_2820|M.avium_104 ----------LHWYVPRSIRLIDVFKGLSPEFVRRSIVKSLPALMPKRQ-
MMAR_2770|M.marinum_M ----------LHWYVPPSVRWIDRLKGVSPEFVRSRILKSLPTFGAGQQ-
MUL_2977|M.ulcerans_Agy99 ----------LHWYVPPSIRWIDRLKGVSPEFVRSRILKSLPTFGTGQQ-
TH_1963|M.thermoresistible__bu SRWGRTRAGRLHWYVPDSLKWIDRLKGVSAEFVRGRIVKQLPALIEEDDR
MLBr_01094|M.leprae_Br4923 --------KKARVLVGPDAKVANVVVRFSGGAGYQRLFAQVASRLILNQR
MSMEG_5053|M.smegmatis_MC2_155 --------NKARVLVGPDAKILDVIVRITG-SGYQRLFSAVAAKAMPR--
MAB_4335|M.abscessus_ATCC_1997 ---------TMSVLPRSTGKFLTRKLGIQDFMLNAHGSDARKAYEDRASH
: .
Mflv_0407|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0267|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1914c|M.bovis_AF2122/97 --------------------------------------------------
Rv1882c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2820|M.avium_104 --------------------------------------------------
MMAR_2770|M.marinum_M --------------------------------------------------
MUL_2977|M.ulcerans_Agy99 --------------------------------------------------
TH_1963|M.thermoresistible__bu MKSPADIEGFEIDSRARQVYGEPHVTADGTTIVPVARVSRRGTGDAARVT
MLBr_01094|M.leprae_Br4923 --------------------------------------------------
MSMEG_5053|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4335|M.abscessus_ATCC_1997 SGPSTE--------------------------------------------
Mflv_0407|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_0267|M.vanbaalenii_PYR-1 --------------------------------------------------
Mb1914c|M.bovis_AF2122/97 --------------------------------------------------
Rv1882c|M.tuberculosis_H37Rv --------------------------------------------------
MAV_2820|M.avium_104 --------------------------------------------------
MMAR_2770|M.marinum_M --------------------------------------------------
MUL_2977|M.ulcerans_Agy99 --------------------------------------------------
TH_1963|M.thermoresistible__bu ARPVGVLVIKDGRATWKPTVDSTRIALFSQLIGLVAAALAGLAMVRRPPW
MLBr_01094|M.leprae_Br4923 --------------------------------------------------
MSMEG_5053|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4335|M.abscessus_ATCC_1997 --------------------------------------------------
Mflv_0407|M.gilvum_PYR-GCK ----------------------
Mvan_0267|M.vanbaalenii_PYR-1 ----------------------
Mb1914c|M.bovis_AF2122/97 ----------------------
Rv1882c|M.tuberculosis_H37Rv ----------------------
MAV_2820|M.avium_104 ----------------------
MMAR_2770|M.marinum_M ----------------------
MUL_2977|M.ulcerans_Agy99 ----------------------
TH_1963|M.thermoresistible__bu PDLHGDISSRPRPARPARSGRR
MLBr_01094|M.leprae_Br4923 ----------------------
MSMEG_5053|M.smegmatis_MC2_155 ----------------------
MAB_4335|M.abscessus_ATCC_1997 ----------------------