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M. thermoresistible (build 8) TH_1963 ()

annotation: PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
coordinates: 3809722 - 3810882
length: 387

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_1963-100% (387)PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE
M. thermoresistible (build 8)TH_3493-2e-3645.25% (179) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3670-4e-1936.84% (171) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1914c-1e-10065.96% (282) short chain dehydrogenase
M. gilvum PYR-GCKMflv_0407-6e-3643.58% (179) short chain dehydrogenase
M. tuberculosis H37RvRv1882c-1e-10065.96% (282) short chain dehydrogenase
M. leprae Br4923MLBr_01094-7e-1532.74% (168) short chain alcohol dehydrogenase
M. abscessus ATCC 19977MAB_1177-1e-2246.23% (106) hypothetical protein MAB_1177
M. marinum MMMAR_2770-6e-9865.71% (280) short-chain type dehydrogenase/reductase
M. avium 104MAV_2820-3e-9662.77% (282) short chain dehydrogenase
M. smegmatis MC2 155MSMEG_3542-1e-2554.08% (98) hypothetical protein MSMEG_3542
M. ulcerans Agy99MUL_2977-3e-9765.70% (277) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_0267-3e-3746.37% (179) short chain dehydrogenase

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_0407|M.gilvum_PYR-GCK          ----MTKSVFITGAATGIGRATALLFAGRGYRVGGYDLDEDGLAVLAADI
Mvan_0267|M.vanbaalenii_PYR-1       ----MTKSVFITGAATGIGRATALLFAQRGYRVGGYDIDEAGLRLLAADI
Mb1914c|M.bovis_AF2122/97           -----MKAIFITGAGSGMGREGATLFHANGWRVGAIDRNEDGLAALRVQL
Rv1882c|M.tuberculosis_H37Rv        -----MKAIFITGAGSGMGREGATLFHANGWRVGAIDRNEDGLAALRVQL
MAV_2820|M.avium_104                -----MKSIFITGAGSGMGREGAKLFHAKGWRVGAVDRNDDGLATLQQEL
MMAR_2770|M.marinum_M               -----MKSVFITGAGSGMGREGAKLFHAKGWRVAAVDRDGAGLDALGAEL
MUL_2977|M.ulcerans_Agy99           -----MKSGFVTGAGSGMGREGAKLFHAKGWRVAAVDRDGAGLDALGAEL
TH_1963|M.thermoresistible__bu      VTRQTARAVFITGAGSGMGRAGAELFHARGWRVGAVDRNAEGLSGLRAQL
MAB_1177|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_3542|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01094|M.leprae_Br4923          MEGFAGKVAVVTGAGSGIGQALAIELARSGAKLAISDVDGEGLAQTEGQL
                                                                                      

Mflv_0407|M.gilvum_PYR-GCK          TAVGGTPVVAHLDVTDPDEVARRLAEFAEG-SGGRIDVLINNAGLLNAGR
Mvan_0267|M.vanbaalenii_PYR-1       TAVGGRPVVGRLDVTDADEVAHRLAEFVDA-AGGRLDVLINNAGLLQAGR
Mb1914c|M.bovis_AF2122/97           GAE--RLWARAVDVTDKAALEGALADFCAGNVGGGLDMMWNNAGIGEGGW
Rv1882c|M.tuberculosis_H37Rv        GAE--RLWARAVDVTDKAALEGALADFCAGNVGGGLDMMWNNAGIGEGGW
MAV_2820|M.avium_104                GDD--RLWTRAVDVTDKAALDGALADFCAGNTGGGLDMMWNNAGIGESGW
MMAR_2770|M.marinum_M               GTE--RLWTRVVDVTDRDALDRALADFCAGTSHGGLDMMWNNAGIGEGGW
MUL_2977|M.ulcerans_Agy99           GTE--RLWTRVVDVTDRDALDRALADFCAGTSHGGLDMMWNNAGIGEGGW
TH_1963|M.thermoresistible__bu      GPE--RLFTGQVDVTDRSALEAGLARFCADNTGGGLDMMWNNAGIGASGW
MAB_1177|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_3542|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01094|M.leprae_Br4923          KAIGASARTDRLDVTEREAFLTYADVVHEN--FGKVNQIYNNAGIAFTGD
                                                                                      

Mflv_0407|M.gilvum_PYR-GCK          FEEIPLEVHHREIEVNVKGVVNGLHAAFPYLKGTPGAVVVNLASASAIYG
Mvan_0267|M.vanbaalenii_PYR-1       FEDIPLPVHHRAIEVNVKGVVNGLHAAFPYLRDTPDAVVVNLSSASAIYG
Mb1914c|M.bovis_AF2122/97           FEDVPYEAAVRVVDVNFKAVLTGAYAALPYLKKAPGSLMFSTSSSSGTYG
Rv1882c|M.tuberculosis_H37Rv        FEDVPYEAAVRVVDVNFKAVLTGAYAALPYLKKAPGSLMFSTSSSSGTYG
MAV_2820|M.avium_104                FEDVPYDAAMRVVDVNYKAVLTGAYGALPYLKKSAGSLMFSTSSSSATYG
MMAR_2770|M.marinum_M               FEDVPYDAAMRVVDVNFKAVLTGAYGALPYLRKAPGSLMFSTSSSSATYG
MUL_2977|M.ulcerans_Agy99           FEDVPYDAAMRVVDVNFKAVLTGAYGALPYLRKAPGSLMFSTSSSSATYG
TH_1963|M.thermoresistible__bu      FEDVPHEAALRVVAINFTAVLTGAYAALPYLRRTPGSLMFSTSSSSATYG
MAB_1177|M.abscessus_ATCC_1997      ---------------------MQLPSSFDGLVTDGGKSIVYGEPYTTADG
MSMEG_3542|M.smegmatis_MC2_155      -MIRPYRDRCEEFPTTMETRAVPIRDALDRLTDDTDASRVFGEPYVTPDG
MLBr_01094|M.leprae_Br4923          VEVSHFKDIERVMDVDYWGVVNGTKAFLPYLISSGDGHVINISSVFGLFS
                                                               :  *    .   .   .     .

Mflv_0407|M.gilvum_PYR-GCK          QAELANYSATKFFVRAITEALNLEWGHYG--IRVIDMWPLYVNTAMTKD-
Mvan_0267|M.vanbaalenii_PYR-1       QVELANYSATKFYVRAITEALNLEWAQHG--IRVIDMWPLYVNTAMTQG-
Mb1914c|M.bovis_AF2122/97           MPRIAVYSATKHAVKGLTEALSVEWQRHG--VRVADVLPGLIDTAILTST
Rv1882c|M.tuberculosis_H37Rv        MPRIAVYSATKHAVKGLTEALSVEWQRHG--VRVADVLPGLIDTAILTST
MAV_2820|M.avium_104                MPRLAVYSSTKHAVKGLTEALSVEWQRHG--VRVADVLPGLIDTAILTTT
MMAR_2770|M.marinum_M               MPRLAVYSATKHAVKGLTEALSAEWRRHG--VRVADVLPGLIDTAILTST
MUL_2977|M.ulcerans_Agy99           MPRLAVYSATKHAVKGLTEALSAEWRRHG--VRVADVLPGLIDTAILTST
TH_1963|M.thermoresistible__bu      MPQLAVYSATKHAVKGLTEALSVEWQRHG--VRVADIA------------
MAB_1177|M.abscessus_ATCC_1997      TLVITVAKVRNRGRGSEGEPLETVAKPLG--VFVIKDGDAQWRPAFN---
MSMEG_3542|M.smegmatis_MC2_155      ATVIPVSTVGRHG-----------ARPAG--VFVVTDGKPVWEPAVD---
MLBr_01094|M.leprae_Br4923          VPGQAAYNSAKFAVRGFTEALREEMALAGRPVNVTTVYPGGIKTAIARN-
                                        .  .  .                 *  : *                

Mflv_0407|M.gilvum_PYR-GCK          ---------------VKTGTTQSLGIRLTAQDIANDIVAAVDATWAR---
Mvan_0267|M.vanbaalenii_PYR-1       ---------------VKTGTTQSLGIRLTAQDIARDIVTAVEATWPR---
Mb1914c|M.bovis_AF2122/97           RQHSDEGPYTISAEQIRAAAPKKGMFRLMPSSSVAEAAWRAYQHPTR---
Rv1882c|M.tuberculosis_H37Rv        RQHSDEGPYTISAEQIRAAAPKKGMFRLMPSSSVAEAAWRAYQHPTR---
MAV_2820|M.avium_104                TNHSNDGAAPMTAEELRATAPKKGMLRLMPASSVAEVAWRAYNHPRR---
MMAR_2770|M.marinum_M               RQHSDASAPTLSSEQIRAAAPKKGMFRLLPASSVAEAAWQAYQHPTR---
MUL_2977|M.ulcerans_Agy99           RQHSDASAPTLSSEQIRAAAPKKGMFRLLPASSVAEAAWHAYQHPTR---
TH_1963|M.thermoresistible__bu      -----------------ARAPRRGMFRLLPPSSVAETAWAAYHDTGRSRW
MAB_1177|M.abscessus_ATCC_1997      -------------------ADRASTLGILTGMLAAALGLLAIIRRPP---
MSMEG_3542|M.smegmatis_MC2_155      -------------------STRIAMLGELIGLVAATLATVAMVRRPP---
MLBr_01094|M.leprae_Br4923          -----------------ATAAEGLDVSKIASRFDTWVAHTSPQHAARIIL
                                                       : .   .                        

Mflv_0407|M.gilvum_PYR-GCK          --KALAQVHFPVGLQAKALALGARFSPAWLTRLVNKGLAGS---------
Mvan_0267|M.vanbaalenii_PYR-1       --RLVKQVHFPVGGQAKALALGSRFSPAWLTRLINKRLAGS---------
Mb1914c|M.bovis_AF2122/97           -------LHWYVPRSIRWIDRLKGVSPEFVRRHIAKSLATLEPKRK----
Rv1882c|M.tuberculosis_H37Rv        -------LHWYVPRSIRWIDRLKGVSPEFVRRHIAKSLATLEPKRK----
MAV_2820|M.avium_104                -------LHWYVPRSIRLIDVFKGLSPEFVRRSIVKSLPALMPKRQ----
MMAR_2770|M.marinum_M               -------LHWYVPPSVRWIDRLKGVSPEFVRSRILKSLPTFGAGQQ----
MUL_2977|M.ulcerans_Agy99           -------LHWYVPPSIRWIDRLKGVSPEFVRSRILKSLPTFGTGQQ----
TH_1963|M.thermoresistible__bu      GRTRAGRLHWYVPDSLKWIDRLKGVSAEFVRGRIVKQLPALIEEDDRMKS
MAB_1177|M.abscessus_ATCC_1997      ------------WPDLTSPGWSPAENPQWWRGRR----------------
MSMEG_3542|M.smegmatis_MC2_155      ------------WPDVRVTVSRKS--------------------------
MLBr_01094|M.leprae_Br4923          KAVRKKKARVLVGPDAKVANVVVRFSGGAGYQRLFAQVASRLILNQR---
                                                  .                                   

Mflv_0407|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0267|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb1914c|M.bovis_AF2122/97           --------------------------------------------------
Rv1882c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_2820|M.avium_104                --------------------------------------------------
MMAR_2770|M.marinum_M               --------------------------------------------------
MUL_2977|M.ulcerans_Agy99           --------------------------------------------------
TH_1963|M.thermoresistible__bu      PADIEGFEIDSRARQVYGEPHVTADGTTIVPVARVSRRGTGDAARVTARP
MAB_1177|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_3542|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01094|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0407|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_0267|M.vanbaalenii_PYR-1       --------------------------------------------------
Mb1914c|M.bovis_AF2122/97           --------------------------------------------------
Rv1882c|M.tuberculosis_H37Rv        --------------------------------------------------
MAV_2820|M.avium_104                --------------------------------------------------
MMAR_2770|M.marinum_M               --------------------------------------------------
MUL_2977|M.ulcerans_Agy99           --------------------------------------------------
TH_1963|M.thermoresistible__bu      VGVLVIKDGRATWKPTVDSTRIALFSQLIGLVAAALAGLAMVRRPPWPDL
MAB_1177|M.abscessus_ATCC_1997      --------------------------------------------------
MSMEG_3542|M.smegmatis_MC2_155      --------------------------------------------------
MLBr_01094|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mflv_0407|M.gilvum_PYR-GCK          -------------------
Mvan_0267|M.vanbaalenii_PYR-1       -------------------
Mb1914c|M.bovis_AF2122/97           -------------------
Rv1882c|M.tuberculosis_H37Rv        -------------------
MAV_2820|M.avium_104                -------------------
MMAR_2770|M.marinum_M               -------------------
MUL_2977|M.ulcerans_Agy99           -------------------
TH_1963|M.thermoresistible__bu      HGDISSRPRPARPARSGRR
MAB_1177|M.abscessus_ATCC_1997      -------------------
MSMEG_3542|M.smegmatis_MC2_155      -------------------
MLBr_01094|M.leprae_Br4923          -------------------