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VEYGMGPELEAFRAEVRAFIAEHAPPIPPRAGVRSAENEAELKALQDWTARLFEAGYVGADWPVEFGGRD DRSAEHAIVVGEELARAAVPGVPSGNALASHALIHYGTDDQRRRHLPEIRAGRQLWCQLFSEPGAGSDLA SLRTRAVLDGDTYTVNGQKVWTTDGHWADYGYLLARTDSDAPKHKGISAFILDMSSPGITVRPLRELTGT SDFNEVFFDSVEVPAEAMIGEPGQGWAIANATLGHERTSVGAAVVKLRLAIEALVQLASHVTVDGRLAID NDRIRDRIGEFSAEVEALSALTYANLTRWLRGTERMHDGAMAKLMFSELNLEMARFAVELGGEAGVLVEG DPDVLDGGRWQDEWLYARAYTIAGGSSEIMRNLIAERGLALPRDRR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2594 | - | - | 100% (396) | acyl-CoA dehydrogenase |
| M. avium 104 | MAV_1878 | - | 0.0 | 84.26% (394) | acyl-CoA dehydrogenase family protein |
| M. avium 104 | MAV_2619 | - | 4e-73 | 42.68% (396) | acyl-CoA dehydrogenase domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1969c | fadE17 | 8e-68 | 38.65% (414) | acyl-CoA dehydrogenase FADE17 |
| M. gilvum PYR-GCK | Mflv_1794 | - | 5e-66 | 40.56% (392) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv1934c | fadE17 | 8e-68 | 38.65% (414) | acyl-CoA dehydrogenase FADE17 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 4e-35 | 31.10% (344) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0597 | - | 1e-63 | 37.50% (392) | acyl-CoA dehydrogenase FadE |
| M. marinum M | MMAR_2862 | fadE17 | 9e-65 | 37.77% (413) | acyl-CoA dehydrogenase FadE17 |
| M. smegmatis MC2 155 | MSMEG_5619 | - | 1e-65 | 40.20% (393) | acyl-CoA dehydrogenase domain-containing protein |
| M. thermoresistible (build 8) | TH_2543 | - | 4e-93 | 45.85% (386) | PUTATIVE putative acyl-CoA dehydrogenase family protein |
| M. ulcerans Agy99 | MUL_4125 | fadE30 | 8e-62 | 36.11% (396) | acyl-CoA dehydrogenase FadE30 |
| M. vanbaalenii PYR-1 | Mvan_4006 | - | 2e-69 | 39.37% (414) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2594|M.avium_104 -----------MEYGMGPELEAFRAEVRAFIAEHAPPIPPRAGVRSAENE
TH_2543|M.thermoresistible__bu --------VGLVTRPTAQHLDEFRARVRTFIAENAPPFQAREGHRAPVDA
Mb1969c|M.bovis_AF2122/97 -----------MDVSYPPEAEAFRDRIREFVAEHLPPGWPGPGALPP--H
Rv1934c|M.tuberculosis_H37Rv -----------MDVSYPPEAEAFRDRIREFVAEHLPPGWPGPGALPP--H
Mvan_4006|M.vanbaalenii_PYR-1 -----------MDVDYPPQAEAFRDRIRALLAEHLPPDWSGGGALAP--E
MMAR_2862|M.marinum_M -----------MDVAYPPEAEEFRERVRAFLDEHLPCGWSGPGALAV--Q
MAB_0597|M.abscessus_ATCC_1997 MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
MUL_4125|M.ulcerans_Agy99 --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
Mflv_1794|M.gilvum_PYR-GCK -------------MS---ELETFRAEVRDWCREHVPADWRAAQSGVG-EE
MSMEG_5619|M.smegmatis_MC2_155 -------------MTHPENLDDFRATVRDWCAAHVPKDWRAAQTGVS-DD
MLBr_00737|M.leprae_Br4923 ----------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAAD
: .: .
MAV_2594|M.avium_104 AELKALQD--WTARLFEAGYVGADWPVEFGGRDDRSAEHAIVVGEELARA
TH_2543|M.thermoresistible__bu TQEKQLRT--WFAALFEAKLIGADWPVEHGGRADHHPLYDRIVSEEILRA
Mb1969c|M.bovis_AF2122/97 EREEFARH--WRRALAGAGLVAVSWPTEYGGG-GLSPMEQVVLAEEFARA
Rv1934c|M.tuberculosis_H37Rv EREEFARH--WRRALAGAGLVAVSWPTEYGGG-GLSPMEQVVLAEEFARA
Mvan_4006|M.vanbaalenii_PYR-1 ERAAVARR--WRQSLAAAGLVAVSWPKAYGGA-GLSVIEQVVLDEEFARA
MMAR_2862|M.marinum_M DRKAFAAR--WRQLLVAAGLIAVSWPKEYGGG-GYSPVEQVVLAEEFARA
MAB_0597|M.abscessus_ATCC_1997 EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGR-GATVSQRVIFYEEYARA
MUL_4125|M.ulcerans_Agy99 EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGR-GLSTAHRVAFYEEYARA
Mflv_1794|M.gilvum_PYR-GCK EFVRFQKA--WFAELHSAGYAVPHWPAQWGG--GLPVDKQVVLYQELAAH
MSMEG_5619|M.smegmatis_MC2_155 EFAAFQKA--WFAELHSAGYAVPHWPAEWGG--GMSVPQQIVLYSELAAH
MLBr_00737|M.leprae_Br4923 VDQRARFPEEALAALNASGFNAIHVPEEYGGQ-GADSVAACIVIEEVARV
* : * ** . . .*
MAV_2594|M.avium_104 AVPGVPSG----NALASHALIHYGTDDQRRRHLPEIRAGRQLWCQLFSEP
TH_2543|M.thermoresistible__bu RAPRPVDQ----VNLAAHVLLHFGSDEQKRTYLPAIRRSEHVWCQLLSEP
Mb1969c|M.bovis_AF2122/97 GAPERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEP
Rv1934c|M.tuberculosis_H37Rv GAPERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEP
Mvan_4006|M.vanbaalenii_PYR-1 GAPERAENDLLGIQLLGNTLIALGTEEQKRHFLPRILSAEDRWCQGFSEP
MMAR_2862|M.marinum_M GAPEREENDLFGVDLLGNTLIALGTEAQKRHFLPRILTGDDRWCQGFSEP
MAB_0597|M.abscessus_ATCC_1997 EAPHKVNH--LGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEP
MUL_4125|M.ulcerans_Agy99 DAPDKVNH--FGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEP
Mflv_1794|M.gilvum_PYR-GCK DAP-RLVLAFVGIHHAASTLLVAGTEEQRRRHLPAILDG-EIWVQGFSEP
MSMEG_5619|M.smegmatis_MC2_155 DAP-RLVLAFVGIHHAASTLLAAGTDAQRNRHLPAILDG-EIWVQGFSEP
MLBr_00737|M.leprae_Br4923 DASASLIP--AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSER
.. *: *: :. ** : **
MAV_2594|M.avium_104 GAGSDLASLRTRAV-LDGDTYTVNGQKVWTTDGHWADYGYLLARTDSDAP
TH_2543|M.thermoresistible__bu DAGSDIAAVRSRAVRLPDGTWRVDGQKTWITDGHWADMGLALLRTDPAAV
Mb1969c|M.bovis_AF2122/97 EAGSDLASVRTRGV-LDGDEWVINGHKIWTSAGTTANWIFLLARTDPSAA
Rv1934c|M.tuberculosis_H37Rv EAGSDLASVRTRGV-LDGDEWVINGHKIWTSAGTTANWIFLLARTDPSAA
Mvan_4006|M.vanbaalenii_PYR-1 EAGSDLASVRTRAV-LDDDEWVINGQKIWTSAGPTANWIFVLARTDTEAP
MMAR_2862|M.marinum_M EAGSDLASVRTRAV-LDGDQWVINGQKIWTSAGSTANWIFVLARTDPVAP
MAB_0597|M.abscessus_ATCC_1997 GAGSDLANVSTSAV-LDGGDWVINGQKVWTSLALQSQWCFVVARTEPGSS
MUL_4125|M.ulcerans_Agy99 GAGSDLANVATTAE-LDGDQWVINGQKVWTSLAHLSQWCFVVARTEKGSK
Mflv_1794|M.gilvum_PYR-GCK EAGSDLAALRTSAR-RVGDEFIVNGQKLWASGGMHADWCLLLARTDPDAP
MSMEG_5619|M.smegmatis_MC2_155 EAGSDLASLRTTAR-AEGDTFVVNGQKLWASGAMYADWCLLLARTDPNAP
MLBr_00737|M.leprae_Br4923 EAGSDAASMRTRAK-ADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKG
**** * : : . .. : ::* * * : . : : *:
MAV_2594|M.avium_104 KHKGISAFILDMSSPGITVRPLRELTGT--SDFNEVFFDSVEVPAEAMIG
TH_2543|M.thermoresistible__bu RHHGLSVFVVPLSAPGVEVRPIRTIGDA--IEVNEVFLTDVRLPAENLIG
Mb1969c|M.bovis_AF2122/97 KHRGLSFLLVPMDQPGVVVRPIVNAAGH--SSFSEVFLTDARTSAGNVVG
Rv1934c|M.tuberculosis_H37Rv KHRGLSFLLVPMDQPGVVVRPIVNAAGH--SSFSEVFLTDARTSAGNVVG
Mvan_4006|M.vanbaalenii_PYR-1 KHKGLSLLLVPIDQPGVVVRPIVNAAGH--ASFSEVFFTDARTPAVNVVG
MMAR_2862|M.marinum_M KHQGLSLLLVPMDQPAVVVRPIVNAAGH--SLFNEVFFADARTGVANVVG
MAB_0597|M.abscessus_ATCC_1997 RHKGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEVFFDNARTSADLVVG
MUL_4125|M.ulcerans_Agy99 RHAGLSYLLVPLDQPSVQIRPIVQITGT--AEFNEVFFDDARTDADLVVG
Mflv_1794|M.gilvum_PYR-GCK KRKGISYFLLDMTSPGVDVRPIRNAIGD--SHFCEIFLDDVRIPATNLIG
MSMEG_5619|M.smegmatis_MC2_155 KRHGISYFMMDMKTPGVDVRPIRNAVGD--SHFCEIFLNDVVIPSANLVG
MLBr_00737|M.leprae_Br4923 AN-GISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIG
. *:* ::: .. : * . *::: . ::*
MAV_2594|M.avium_104 EPGQGWAIANATLGHERTSVGAAVVKLRL-AIEALVQLASHVTVDGRLAI
TH_2543|M.thermoresistible__bu AEGQGWSIIMAGLDFERFGIGGNVILLEL-LIDDLLTLARHLQVDGRPAI
Mb1969c|M.bovis_AF2122/97 RVGDGWSTAMTLLGFER---GSHIATAAI-DFERDLQRLCELARDRGLHT
Rv1934c|M.tuberculosis_H37Rv RVGDGWSTAMTLLGFER---GSHIATAAI-DFERDLQRLCELARDRGLHT
Mvan_4006|M.vanbaalenii_PYR-1 RVGDGWPAAMTVLGFER---GSQVTTAAI-NFGREMDRLRELARDRGLHT
MMAR_2862|M.marinum_M EVGSGWTAAMSLLGFER---GAQATTGAI-DFARDLSRLCDLARARGLDS
MAB_0597|M.abscessus_ATCC_1997 EPGDGWRVAMGTLTFER---GVSTLGNQI-TYARELSRLAELAKSNGAAD
MUL_4125|M.ulcerans_Agy99 APGDGWRVAMGTLTFER---GVSTLGQQI-VYARELSDLAALARRTGAAD
Mflv_1794|M.gilvum_PYR-GCK AENAGWQVAQETLGAER---GMTMLELAE-RLG--NAGFRWLVES-APVD
MSMEG_5619|M.smegmatis_MC2_155 PVNKGWQVAQATLGAER---GMTMLELAE-RLG--NAGFRWLVDACSPVD
MLBr_00737|M.leprae_Br4923 EPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESIS
. *: * * *
MAV_2594|M.avium_104 DNDRIRDRIGEFSAEVEALSALTYANLTRWLRGTERM-HDGAMAKLMFSE
TH_2543|M.thermoresistible__bu EVADIRQRIAELAVEVEVAKAFIDDHVEQLINGREQP-GDSSIAKLSFAE
Mb1969c|M.bovis_AF2122/97 D-PRVRDGLAWCYARVQIMRYRGYRDLTLALTGRPPG-AEAAITKVIWSE
Rv1934c|M.tuberculosis_H37Rv D-PRVRDGLAWCYARVQIMRYRGYRDLTLALTGRPPG-AEAAITKVIWSE
Mvan_4006|M.vanbaalenii_PYR-1 D-ARIRDGLAWCYSRVQIMRFQGYRGLTSLLAGQRPG-REAAISKVVWSE
MMAR_2862|M.marinum_M D-PRIRDRLAWCYSRTQIMRYRGYRSLTWALNGLLPG-AEAAISKVIWSE
MAB_0597|M.abscessus_ATCC_1997 D-PAIRERLAQAYVGMRTMRAYALATMDEERPG------QDNVSKLLWAN
MUL_4125|M.ulcerans_Agy99 D-PFIREHLTRAWTGLRAMRSYALATMDVEQPG------QDNVSKLLWAN
Mflv_1794|M.gilvum_PYR-GCK D-PIVADRLAGFETELAALRGMCRRMVEH---GPSGP-ADPSVVKLYYSE
MSMEG_5619|M.smegmatis_MC2_155 D-PVVADRLAQFEIELTGLRGLCRDLVERSETGEAGP-ADASIVKLYYSE
MLBr_00737|M.leprae_Br4923 TFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASD
: : * * ::
MAV_2594|M.avium_104 LNLEMARFAVELGGEAGVLVEGDP----------DVLDG-GRWQDEWLYA
TH_2543|M.thermoresistible__bu TYHTVAAYGADLASWGTSFQPADS----------PVAQARQRLRECWLWS
Mb1969c|M.bovis_AF2122/97 YFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMDELLYA
Rv1934c|M.tuberculosis_H37Rv YFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPACWMDELLYA
Mvan_4006|M.vanbaalenii_PYR-1 FFRRYTELAVEILGLEALSPAGPGNGEALIVPEPGTPNSAACWMDELLYA
MMAR_2862|M.marinum_M YFQRYTELAVEILGLDALCPSGPGNGEARVVPQAGTANSPACWMDELLYA
MAB_0597|M.abscessus_ATCC_1997 WHRDLGELAMEIIGTSTLLTN---------------AGEMDEWQRLFLFS
MUL_4125|M.ulcerans_Agy99 WHRSLGELAMDVIGKPGLTLA---------------DGEFDEWQRLFLFT
Mflv_1794|M.gilvum_PYR-GCK LLQRLTDFGAEIGGLPAHTVLTKP---------MSSGWESGSWVLDFVGS
MSMEG_5619|M.smegmatis_MC2_155 LLQRMTDFGAQIAGLPAHTVLTKP---------ASSGWESGAWMLDFIGS
MLBr_00737|M.leprae_Br4923 IAMEVTTDAVQLFGGAGYTSDFP-------------------VERFMRDA
. :: . :
MAV_2594|M.avium_104 RAYTIAGGSSEIMRNLIAERGLALPRDRR---------------
TH_2543|M.thermoresistible__bu RAYTISGGSSEMMRNILAKRRLKLPTT-----------------
Mb1969c|M.bovis_AF2122/97 RAATIYAGSSQIQRNVIGERLLGLPKEPR------PEVLC----
Rv1934c|M.tuberculosis_H37Rv RAATIYAGSSQIQRNVIGERLLGLPKEPR------PEVLC----
Mvan_4006|M.vanbaalenii_PYR-1 RASTIYAGSSQIQRNVIGEQLLGLPREPRVPAGRVPEPAGRGSN
MMAR_2862|M.marinum_M RAATIYAGSSQIQRNVIGEQLLGLPKEPR------REAVH----
MAB_0597|M.abscessus_ATCC_1997 RADTIYGGSNEIQRNIISERVLGLPREAR---------------
MUL_4125|M.ulcerans_Agy99 RADTIYGGSNEIQRNIIAERVLGLPREAKG--------------
Mflv_1794|M.gilvum_PYR-GCK WEWTIPGGASEIQRTIIGERGLGLPREPSAL-------------
MSMEG_5619|M.smegmatis_MC2_155 WEWTIPGGASEIQRTIIGERGLGLPREPSAV-------------
MLBr_00737|M.leprae_Br4923 KITQIYEGTNQIQRVVMSRALLR---------------------
* *:.:: * ::.. *