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QDVEEFRAEVRGWLAANLVGEFATLKGLGGPGREHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTA HRVAFYEEYARADAPDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAGSDLANVA TTAELDGDQWVINGQKVWTSLAHLSQWCFVVARTEKGSKRHAGLSYLLVPLDQPSVQIRPIVQITGTAEF NEVFFDDARTDADLVVGAPGDGWRVAMGTLTFERGVSTLGQQIVYARELSDLAALARRTGAADDPFIREH LTRAWTGLRAMRSYALATMDVEQPGQDNVSKLLWANWHRSLGELAMDVIGKPGLTLADGEFDEWQRLFLF TRADTIYGGSNEIQRNIIAERVLGLPREAKG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_4125 | fadE30 | - | 100% (382) | acyl-CoA dehydrogenase FadE30 |
| M. ulcerans Agy99 | MUL_2892 | fadE17 | 4e-83 | 45.26% (380) | acyl-CoA dehydrogenase FadE17 |
| M. ulcerans Agy99 | MUL_4127 | fadE31 | 7e-63 | 37.01% (381) | acyl-CoA dehydrogenase FadE31 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3590c | fadE30 | 0.0 | 92.47% (385) | acyl-CoA dehydrogenase FADE30 |
| M. gilvum PYR-GCK | Mflv_1481 | - | 0.0 | 85.22% (379) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv3560c | fadE30 | 0.0 | 92.47% (385) | acyl-CoA dehydrogenase FADE30 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 4e-23 | 27.86% (341) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0597 | - | 0.0 | 80.37% (377) | acyl-CoA dehydrogenase FadE |
| M. marinum M | MMAR_5049 | fadE30 | 0.0 | 99.48% (382) | acyl-CoA dehydrogenase FadE30 |
| M. avium 104 | MAV_0601 | - | 0.0 | 95.03% (382) | putative acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_6012 | - | 0.0 | 84.87% (390) | putative acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_4263 | - | 0.0 | 83.95% (380) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. vanbaalenii PYR-1 | Mvan_5285 | - | 0.0 | 85.86% (382) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MUL_4125|M.ulcerans_Agy99 --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
MMAR_5049|M.marinum_M --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
Mb3590c|M.bovis_AF2122/97 --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
Rv3560c|M.tuberculosis_H37Rv --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
MAV_0601|M.avium_104 --------------MQDV--EEFRAEVRSWLADNLVGEFAALKGLGGPGR
Mflv_1481|M.gilvum_PYR-GCK --------------MIEV--QKFRAEVRDWLAENLVGDFAALKGLGGPGR
Mvan_5285|M.vanbaalenii_PYR-1 --------------MIEV--QEFRAEVRDWLAENLVGEYAALKGLGGPGR
MSMEG_6012|M.smegmatis_MC2_155 --------------MIEV--QEFRAEVRQWLADNLVGDFAALKGLGGPGR
TH_4263|M.thermoresistible__bu --------------VIEV--HEFRAEVRQWLADNLVGEYAALKGLGGPGR
MAB_0597|M.abscessus_ATCC_1997 MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
MLBr_00737|M.leprae_Br4923 ----------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAAD
: . .: . * : ..
MUL_4125|M.ulcerans_Agy99 EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
MMAR_5049|M.marinum_M EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
Mb3590c|M.bovis_AF2122/97 EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
Rv3560c|M.tuberculosis_H37Rv EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
MAV_0601|M.avium_104 EHEAFEERRAWNQHLAKAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
Mflv_1481|M.gilvum_PYR-GCK EHEAFEERLAWNQHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
Mvan_5285|M.vanbaalenii_PYR-1 EHEAFEERLAWNRHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
MSMEG_6012|M.smegmatis_MC2_155 EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSVAHRVAFYEEYARAN
TH_4263|M.thermoresistible__bu EHEAFEERLEWNRKLAAAGLTCLGWPVEHGGRGLSVAHRVAFYEEYALAN
MAB_0597|M.abscessus_ATCC_1997 EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYARAE
MLBr_00737|M.leprae_Br4923 VDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
.: . * :* ..: * *:**:* . ** * .:
MUL_4125|M.ulcerans_Agy99 APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
MMAR_5049|M.marinum_M APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
Mb3590c|M.bovis_AF2122/97 APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
Rv3560c|M.tuberculosis_H37Rv APDKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGAG
MAV_0601|M.avium_104 APDKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGAG
Mflv_1481|M.gilvum_PYR-GCK APDKVNHLGEELLGPTLIAYGTPEQQQRFLPRILDVTELWSQGYSEPGAG
Mvan_5285|M.vanbaalenii_PYR-1 APDKVNHLGEELLGPTLIAYGTPEQQQRFLPKILDVTELWSQGYSEPGAG
MSMEG_6012|M.smegmatis_MC2_155 APDKVNHFGEELLGPTLIEYGTPEQQKRFLPKILDVTELWCQGYSEPNAG
TH_4263|M.thermoresistible__bu APAKVNHLGEELLGPTLIEYGTPEQQQRFLPRILDVTELWAQGYSEPGAG
MAB_0597|M.abscessus_ATCC_1997 APHKVNHLGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEPGAG
MLBr_00737|M.leprae_Br4923 ASASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAG
*. .: ::* ** *: : :::.** : : . . ** **
MUL_4125|M.ulcerans_Agy99 SDLANVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
MMAR_5049|M.marinum_M SDLANVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
Mb3590c|M.bovis_AF2122/97 SDLASVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVLAR
Rv3560c|M.tuberculosis_H37Rv SDLASVATTAELD----------GDQWVINGQKVWTSLAHLSQWCFVLAR
MAV_0601|M.avium_104 SDLANVSTTAELD----------GDQWVINGQKVWTSLAHLSQWCFVVAR
Mflv_1481|M.gilvum_PYR-GCK SDLANVSTTATLD----------GDEWVINGQKVWTSLAHWAQWCFVVAR
Mvan_5285|M.vanbaalenii_PYR-1 SDLANVSTTAVLDE--------EGRQWHINGQKVWTSLAHWAQWCFVVAR
MSMEG_6012|M.smegmatis_MC2_155 SDLANVSTTAELVGDAEASGATGNQYWVINGQKVWTSLAHWAQWCFVVAR
TH_4263|M.thermoresistible__bu SDLANVSTTAVLD----------GDQWVINGQKVWTSLAHWAQWCFVVAR
MAB_0597|M.abscessus_ATCC_1997 SDLANVSTSAVLD----------GGDWVINGQKVWTSLALQSQWCFVVAR
MLBr_00737|M.leprae_Br4923 SDAASMRTRAKAD----------GDDWILNGFKCWITNGGKSTWYTVMAV
** *.: * * . * :** * * : . : * *:*
MUL_4125|M.ulcerans_Agy99 TEKGSKRHAGLSYLLVPLDQPSVQIRPIVQITGT--AEFNEVFFDDARTD
MMAR_5049|M.marinum_M TEKGSKRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
Mb3590c|M.bovis_AF2122/97 TEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
Rv3560c|M.tuberculosis_H37Rv TEKGSQRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
MAV_0601|M.avium_104 TEKGSKRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTD
Mflv_1481|M.gilvum_PYR-GCK TEKGSKRHAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDARTA
Mvan_5285|M.vanbaalenii_PYR-1 TEKGSKRHAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDARTD
MSMEG_6012|M.smegmatis_MC2_155 TEKGSKRHAGLSYLLVPLDQPGVEIRPINQLTGD--SEFNEVFFDDARTE
TH_4263|M.thermoresistible__bu TERGSKRHHGLSYLLVPLDQPGVEIRPIVQLTGD--SEFNEVFFDNARTD
MAB_0597|M.abscessus_ATCC_1997 TEPGSSRHKGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEVFFDNARTS
MLBr_00737|M.leprae_Br4923 TDP-DKGANGISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIP
*: .. *:* ::* :: ...* * : * : .*::**..*
MUL_4125|M.ulcerans_Agy99 ADLVVGAPGDGWRVAMGTLTFER---GVSTLGQQIVYARELSDLAALARR
MMAR_5049|M.marinum_M ADLVVGAPGDGWRVAMGTLTFER---GVSTLGQQIVYARELSDLAALARR
Mb3590c|M.bovis_AF2122/97 ADLVVGAPGDGWRVAMATLTFER---GVSTLGQQIVYARELSNLVELARR
Rv3560c|M.tuberculosis_H37Rv ADLVVGAPGDGWRVAMATLTFER---GVSTLGQQIVYARELSNLVELARR
MAV_0601|M.avium_104 ASMVVGQPGDGWRVAMGTLTFER---GVSTLGQQIRYARELSNLAELARR
Mflv_1481|M.gilvum_PYR-GCK ADLVVGEPGDGWRVAMGTLTFER---GVSTLGQQIRYAREHSNLVELAEK
Mvan_5285|M.vanbaalenii_PYR-1 ADLVVGEPGDGWRVAMGTLTFER---GVSTLGQQIRYAREHSNLVELAKR
MSMEG_6012|M.smegmatis_MC2_155 AGLVVGQPGDGWRVAMGTLTFER---GVSTLGQQIRYAREHSNLVELAKR
TH_4263|M.thermoresistible__bu ASMVVGEPGDGWRVAMGTLTFER---GVSTLGQQIQYRRELEGVVELAKR
MAB_0597|M.abscessus_ATCC_1997 ADLVVGEPGDGWRVAMGTLTFER---GVSTLGNQITYARELSRLAELAKS
MLBr_00737|M.leprae_Br4923 GDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQ
.. ::* ** *::.*:.** . * *..::* . .
MUL_4125|M.ulcerans_Agy99 TGAADDPFIREHLTRAWTGLRAMRSYALATMD---VEQPGQDNVSKLLWA
MMAR_5049|M.marinum_M TGAADDPFIRERLTRAWTGLRAMRSYALATMD---VEQPGQDNVSKLLWA
Mb3590c|M.bovis_AF2122/97 TAAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWA
Rv3560c|M.tuberculosis_H37Rv TAAADDPLIRERLTRAWTGLRAMRSYALATMEGPAVEQPGQDNVSKLLWA
MAV_0601|M.avium_104 NGAADDPFIRERLTRAWTGLRAMRSYALATMD---VEQPGQDNVSKLLWA
Mflv_1481|M.gilvum_PYR-GCK TGAADDPLIRERLVRSWAGLKAMRSYALATMD---VEKPGQDNISKLLWA
Mvan_5285|M.vanbaalenii_PYR-1 TGAADDPLIRERLTRSWAGLKAMRSYALATMD---VEQPGMDNVSKLLWA
MSMEG_6012|M.smegmatis_MC2_155 TGAADDPLIRERLVQSWTGLQAMRSYALATMD---VEQPGQDNVSKLLWA
TH_4263|M.thermoresistible__bu TGAIDDPLIRERLTRSWVGLRTMRSYALATMD---DERPGQDNISKLLWA
MAB_0597|M.abscessus_ATCC_1997 NGAADDPAIRERLAQAYVGMRTMRAYALATMD---EERPGQDNVSKLLWA
MLBr_00737|M.leprae_Br4923 FGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPD--LGFISA
. .. :: : .::. : :. *: * :: *
MUL_4125|M.ulcerans_Agy99 NWHRSLGELAMDVIGKPGLTLADGEFD---EWQRLFLFTRADTIYGGSNE
MMAR_5049|M.marinum_M NWHRSLGELAMDVIGKPGLTLADGEFD---EWQRLFLFTRADTIYGGSNE
Mb3590c|M.bovis_AF2122/97 NWHRNLGELAMDVIGKPGMTMPDGEFD---EWQRLYLFTRADTIYGGSNE
Rv3560c|M.tuberculosis_H37Rv NWHRNLGELAMDVIGKPGMTMPDGEFD---EWQRLYLFTRADTIYGGSNE
MAV_0601|M.avium_104 NWHRALGELAMDVIGKPGMTMPDGEFD---EWQRLFLFTRADTIYGGSNE
Mflv_1481|M.gilvum_PYR-GCK NWHRELGEIAMDIEGAAGLTLPDGEFS---EWQRLYLFSRSDTIYGGSNE
Mvan_5285|M.vanbaalenii_PYR-1 NWHRELGEIAMDVQGMAGLTLPGGEFD---EWQRLYLFSRSDTIYGGSNE
MSMEG_6012|M.smegmatis_MC2_155 NWHRELGEIAMDVQGMAGLTLENGEFD---EWQRLYLFSRADTIYGGSNE
TH_4263|M.thermoresistible__bu NWHRELGEIAMDVVGMAGLTLTDGDFD---EWQRLYLFSRSDTIYGGSNE
MAB_0597|M.abscessus_ATCC_1997 NWHRDLGELAMEIIGTSTLLTNAGEMD---EWQRLFLFSRADTIYGGSNE
MLBr_00737|M.leprae_Br4923 ASKCFASDIAMEVTTDAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQ
: .::**:: . . :*: :: ** *:*:
MUL_4125|M.ulcerans_Agy99 IQRNIIAERVLGLPREAKG
MMAR_5049|M.marinum_M IQRNIIAERVLGLPREAKG
Mb3590c|M.bovis_AF2122/97 IQRNIIAERVLGLPREAKG
Rv3560c|M.tuberculosis_H37Rv IQRNIIAERVLGLPREAKG
MAV_0601|M.avium_104 IQRNIIAERVLGLPREVKG
Mflv_1481|M.gilvum_PYR-GCK IQRNIIAERVLGLPREARH
Mvan_5285|M.vanbaalenii_PYR-1 IQRNIIAERVLGLPREAKG
MSMEG_6012|M.smegmatis_MC2_155 IQRNIIAERVLGLPREVKG
TH_4263|M.thermoresistible__bu IQRNIIAERVLGLPREPKG
MAB_0597|M.abscessus_ATCC_1997 IQRNIISERVLGLPREAR-
MLBr_00737|M.leprae_Br4923 IQRVVMSRALLR-------
*** :::. :*