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M. thermoresistible (build 8) TH_2543 (-)

annotation: putative acyl-CoA dehydrogenase family protein
coordinates: 3431975 - 3433174
length: 400

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2543--100% (400)putative acyl-CoA dehydrogenase family protein
M. thermoresistible (build 8)TH_3884-2e-5435.52% (397) PUTATIVE acyl-CoA dehydrogenase protein
M. thermoresistible (build 8)TH_4120-5e-5433.94% (386) PUTATIVE putative acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1969cfadE171e-5234.56% (408) acyl-CoA dehydrogenase FADE17
M. gilvum PYR-GCKMflv_1794-8e-4635.16% (401) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37RvRv1934cfadE171e-5234.56% (408) acyl-CoA dehydrogenase FADE17
M. leprae Br4923MLBr_00737fadE256e-1927.16% (324) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977MAB_0597-4e-5035.20% (392) acyl-CoA dehydrogenase FadE
M. marinum MMMAR_5049fadE303e-4834.34% (396) acyl-CoA dehydrogenase FadE30
M. avium 104MAV_1878-8e-9847.41% (386) acyl-CoA dehydrogenase family protein
M. smegmatis MC2 155MSMEG_6012-3e-4834.41% (404) putative acyl-CoA dehydrogenase
M. ulcerans Agy99MUL_4125fadE303e-4733.84% (396) acyl-CoA dehydrogenase FadE30
M. vanbaalenii PYR-1Mvan_4006-1e-4933.25% (400) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


TH_2543|M.thermoresistible__bu      --------VGLVTRPTAQHLDEFRARVRTFIAENAPPFQAREGHR--APV
MAV_1878|M.avium_104                --------MEYGMRP---ELAEFRAEVRAFVAEHAPAIPPRAGVR--SAE
Mb1969c|M.bovis_AF2122/97           -----------MDVSYPPEAEAFRDRIREFVAEHLPPGWPGPGAL--PPH
Rv1934c|M.tuberculosis_H37Rv        -----------MDVSYPPEAEAFRDRIREFVAEHLPPGWPGPGAL--PPH
Mvan_4006|M.vanbaalenii_PYR-1       -----------MDVDYPPQAEAFRDRIRALLAEHLPPDWSGGGAL--APE
MMAR_5049|M.marinum_M               --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
MUL_4125|M.ulcerans_Agy99           --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
MSMEG_6012|M.smegmatis_MC2_155      --------------MIEV--QEFRAEVRQWLADNLVGDFAALKGLGGPGR
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
Mflv_1794|M.gilvum_PYR-GCK          --------------MSEL--ETFRAEVRDWCREHVPADWRAAQSG---VG
MLBr_00737|M.leprae_Br4923          ----------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAAD
                                                          .:   .                      

TH_2543|M.thermoresistible__bu      DATQEKQLRTWFAALFEAKLIGADWPVEHGGRADHHPLYDRIVSEEILRA
MAV_1878|M.avium_104                NDAEFKALQEWTGRLFEAGYVGADWPVEFGGRGDFTPEHSIIVGEELARA
Mb1969c|M.bovis_AF2122/97           EREEFARH--WRRALAGAGLVAVSWPTEYGGG-GLSPMEQVVLAEEFARA
Rv1934c|M.tuberculosis_H37Rv        EREEFARH--WRRALAGAGLVAVSWPTEYGGG-GLSPMEQVVLAEEFARA
Mvan_4006|M.vanbaalenii_PYR-1       ERAAVARR--WRQSLAAAGLVAVSWPKAYGGA-GLSVIEQVVLDEEFARA
MMAR_5049|M.marinum_M               EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGR-GLSTAHRVAFYEEYARA
MUL_4125|M.ulcerans_Agy99           EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGR-GLSTAHRVAFYEEYARA
MSMEG_6012|M.smegmatis_MC2_155      EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGR-GLSVAHRVAFYEEYARA
MAB_0597|M.abscessus_ATCC_1997      EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGR-GATVSQRVIFYEEYARA
Mflv_1794|M.gilvum_PYR-GCK          EEEFVRFQKAWFAELHSAGYAVPHWPAQWGG--GLPVDKQVVLYQELAAH
MLBr_00737|M.leprae_Br4923          VDQRARFPEEALAALNASGFNAIHVPEEYGGQ-GADSVAACIVIEEVARV
                                                  *  :       *   **  .        . :*    

TH_2543|M.thermoresistible__bu      RAPRPVD----QVNLAAHVLLHFGSDEQKRTYLPAIRRSEHVWCQLLSEP
MAV_1878|M.avium_104                QAPSAQS----GSVLASHALIHYGTDEQRRRHLPEIRGGRELWCQLFSEP
Mb1969c|M.bovis_AF2122/97           GAPERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEP
Rv1934c|M.tuberculosis_H37Rv        GAPERAENDLLGIDLLGNTLIALGSEAQKRHFLPRILSGEHRWCQGFSEP
Mvan_4006|M.vanbaalenii_PYR-1       GAPERAENDLLGIQLLGNTLIALGTEEQKRHFLPRILSAEDRWCQGFSEP
MMAR_5049|M.marinum_M               DAPDKVN--HFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEP
MUL_4125|M.ulcerans_Agy99           DAPDKVN--HFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEP
MSMEG_6012|M.smegmatis_MC2_155      NAPDKVN--HFGEELLGPTLIEYGTPEQQKRFLPKILDVTELWCQGYSEP
MAB_0597|M.abscessus_ATCC_1997      EAPHKVN--HLGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEP
Mflv_1794|M.gilvum_PYR-GCK          DAPRLVLA-FVGIHHAASTLLVAGTEEQRRRHLPAILDG-EIWVQGFSEP
MLBr_00737|M.leprae_Br4923          DASASLIP--AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSER
                                     *.                *:  *:   ::  ** :           ** 

TH_2543|M.thermoresistible__bu      DAGSDIAAVRSRAVRLPDG---------TWRVDGQKTWITDGHWADMGLA
MAV_1878|M.avium_104                GAGSDLASLRTRAVRHGD----------TYTIDGQKVWTTDGHWARYGYL
Mb1969c|M.bovis_AF2122/97           EAGSDLASVRTRGVLDGDE----------WVINGHKIWTSAGTTANWIFL
Rv1934c|M.tuberculosis_H37Rv        EAGSDLASVRTRGVLDGDE----------WVINGHKIWTSAGTTANWIFL
Mvan_4006|M.vanbaalenii_PYR-1       EAGSDLASVRTRAVLDDDE----------WVINGQKIWTSAGPTANWIFV
MMAR_5049|M.marinum_M               GAGSDLANVATTAELDGDQ----------WVINGQKVWTSLAHLSQWCFV
MUL_4125|M.ulcerans_Agy99           GAGSDLANVATTAELDGDQ----------WVINGQKVWTSLAHLSQWCFV
MSMEG_6012|M.smegmatis_MC2_155      NAGSDLANVSTTAELVGDAEASGATGNQYWVINGQKVWTSLAHWAQWCFV
MAB_0597|M.abscessus_ATCC_1997      GAGSDLANVSTSAVLDGGD----------WVINGQKVWTSLALQSQWCFV
Mflv_1794|M.gilvum_PYR-GCK          EAGSDLAALRTSARRVGDE----------FIVNGQKLWASGGMHADWCLL
MLBr_00737|M.leprae_Br4923          EAGSDAASMRTRAKADGDD----------WILNGFKCWITNGGKSTWYTV
                                     **** * : : .    .           : ::* * * : .  :     

TH_2543|M.thermoresistible__bu      LLRTDPAAVRHHGLSVFVVPLSAPGVEVRPIRTIGDA--IEVNEVFLTDV
MAV_1878|M.avium_104                LARTDPDAPKHKGISAFILDMSAPGVSVRPLRELTGT--SDFNEVFFDGV
Mb1969c|M.bovis_AF2122/97           LARTDPSAAKHRGLSFLLVPMDQPGVVVRPIVNAAGH--SSFSEVFLTDA
Rv1934c|M.tuberculosis_H37Rv        LARTDPSAAKHRGLSFLLVPMDQPGVVVRPIVNAAGH--SSFSEVFLTDA
Mvan_4006|M.vanbaalenii_PYR-1       LARTDTEAPKHKGLSLLLVPIDQPGVVVRPIVNAAGH--ASFSEVFFTDA
MMAR_5049|M.marinum_M               VARTEKGSKRHAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDA
MUL_4125|M.ulcerans_Agy99           VARTEKGSKRHAGLSYLLVPLDQPSVQIRPIVQITGT--AEFNEVFFDDA
MSMEG_6012|M.smegmatis_MC2_155      VARTEKGSKRHAGLSYLLVPLDQPGVEIRPINQLTGD--SEFNEVFFDDA
MAB_0597|M.abscessus_ATCC_1997      VARTEPGSSRHKGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEVFFDNA
Mflv_1794|M.gilvum_PYR-GCK          LARTDPDAPKRKGISYFLLDMTSPGVDVRPIRNAIGD--SHFCEIFLDDV
MLBr_00737|M.leprae_Br4923          MAVTDPDKGAN-GISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKC
                                    :  *:     . *:* :::     .. : *     .       *:::   

TH_2543|M.thermoresistible__bu      RLPAENLIGAEGQGWSIIMAGLDFER-FGIGGNVILLELLIDDLLTLARH
MAV_1878|M.avium_104                EVPADAMIGAPGQGWAIANATLAHER-TNVGGIVVKLRLAIDALIDLARR
Mb1969c|M.bovis_AF2122/97           RTSAGNVVGRVGDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARD
Rv1934c|M.tuberculosis_H37Rv        RTSAGNVVGRVGDGWSTAMTLLGFERGSHIATAAIDFERDLQRLCELARD
Mvan_4006|M.vanbaalenii_PYR-1       RTPAVNVVGRVGDGWPAAMTVLGFERGSQVTTAAINFGREMDRLRELARD
MMAR_5049|M.marinum_M               RTDADLVVGAPGDGWRVAMGTLTFERGVSTLGQQIVYARELSDLAALARR
MUL_4125|M.ulcerans_Agy99           RTDADLVVGAPGDGWRVAMGTLTFERGVSTLGQQIVYARELSDLAALARR
MSMEG_6012|M.smegmatis_MC2_155      RTEAGLVVGQPGDGWRVAMGTLTFERGVSTLGQQIRYAREHSNLVELAKR
MAB_0597|M.abscessus_ATCC_1997      RTSADLVVGEPGDGWRVAMGTLTFERGVSTLGNQITYARELSRLAELAKS
Mflv_1794|M.gilvum_PYR-GCK          RIPATNLIGAENAGWQVAQETLGAERGMTMLELAERLG--NAGFRWLVES
MLBr_00737|M.leprae_Br4923          RIPGDRIIGEPGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKD
                                    .  .  ::*  . *:      *   *                     .. 

TH_2543|M.thermoresistible__bu      LQVDGRPAIEVADIRQRIAELAVEVEVAKAFIDDHVEQLINGREQP-GDS
MAV_1878|M.avium_104                VTIDGGPAIDSDRVRDRIGQFSAEVEALSALTYANLTRWLRGRERM-HDA
Mb1969c|M.bovis_AF2122/97           RGLHTDPRV-----RDGLAWCYARVQIMRYRGYRDLTLALTGRPPG-AEA
Rv1934c|M.tuberculosis_H37Rv        RGLHTDPRV-----RDGLAWCYARVQIMRYRGYRDLTLALTGRPPG-AEA
Mvan_4006|M.vanbaalenii_PYR-1       RGLHTDARI-----RDGLAWCYSRVQIMRFQGYRGLTSLLAGQRPG-REA
MMAR_5049|M.marinum_M               TGAADDPFI-----RERLTRAWTGLRAMRSYALATMDVEQPGQ------D
MUL_4125|M.ulcerans_Agy99           TGAADDPFI-----REHLTRAWTGLRAMRSYALATMDVEQPGQ------D
MSMEG_6012|M.smegmatis_MC2_155      TGAADDPLI-----RERLVQSWTGLQAMRSYALATMDVEQPGQ------D
MAB_0597|M.abscessus_ATCC_1997      NGAADDPAI-----RERLAQAYVGMRTMRAYALATMDEERPGQ------D
Mflv_1794|M.gilvum_PYR-GCK          -APVDDPIV-----ADRLAGFETELAALRGMCRRMVEHGPSGP----ADP
MLBr_00737|M.leprae_Br4923          RKQFGESISTFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFIS
                                          .          :      :                *        

TH_2543|M.thermoresistible__bu      SIAKLSFAETYHTVAAYGADLASWGTSFQPADSP----------VAQARQ
MAV_1878|M.avium_104                AMGKLMFSEINLEMAAFAVELAGEAGVLVEGDDN----------VLDG-G
Mb1969c|M.bovis_AF2122/97           AITKVIWSEYFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPA
Rv1934c|M.tuberculosis_H37Rv        AITKVIWSEYFRRYTDLAVEILGLEALGPRGPGNGGARLVPEAGTPNSPA
Mvan_4006|M.vanbaalenii_PYR-1       AISKVVWSEFFRRYTELAVEILGLEALSPAGPGNGEALIVPEPGTPNSAA
MMAR_5049|M.marinum_M               NVSKLLWANWHRSLGELAMDVIGKPGLTLAD---------------GEFD
MUL_4125|M.ulcerans_Agy99           NVSKLLWANWHRSLGELAMDVIGKPGLTLAD---------------GEFD
MSMEG_6012|M.smegmatis_MC2_155      NVSKLLWANWHRELGEIAMDVQGMAGLTLEN---------------GEFD
MAB_0597|M.abscessus_ATCC_1997      NVSKLLWANWHRDLGELAMEIIGTSTLLTNA---------------GEMD
Mflv_1794|M.gilvum_PYR-GCK          SVVKLYYSELLQRLTDFGAEIGGLPAHTVLTKPMSSG---------WESG
MLBr_00737|M.leprae_Br4923          AASKCFASDIAMEVTTDAVQLFGGAGYTSDFP------------------
                                       *   ::        . :: .                           

TH_2543|M.thermoresistible__bu      RLRECWLWSRAYTISGGSSEMMRNILAKRRLKLPTT--------------
MAV_1878|M.avium_104                RWQDEWLYARAYTIAGGSSEIMRNLIAERGLGLPRD--------------
Mb1969c|M.bovis_AF2122/97           CWMDELLYARAATIYAGSSQIQRNVIGERLLGLPKEPR------PEVLC-
Rv1934c|M.tuberculosis_H37Rv        CWMDELLYARAATIYAGSSQIQRNVIGERLLGLPKEPR------PEVLC-
Mvan_4006|M.vanbaalenii_PYR-1       CWMDELLYARASTIYAGSSQIQRNVIGEQLLGLPREPRVPAGRVPEPAGR
MMAR_5049|M.marinum_M               EWQRLFLFTRADTIYGGSNEIQRNIIAERVLGLPREAKG-----------
MUL_4125|M.ulcerans_Agy99           EWQRLFLFTRADTIYGGSNEIQRNIIAERVLGLPREAKG-----------
MSMEG_6012|M.smegmatis_MC2_155      EWQRLYLFSRADTIYGGSNEIQRNIIAERVLGLPREVKG-----------
MAB_0597|M.abscessus_ATCC_1997      EWQRLFLFSRADTIYGGSNEIQRNIISERVLGLPREAR------------
Mflv_1794|M.gilvum_PYR-GCK          SWVLDFVGSWEWTIPGGASEIQRTIIGERGLGLPREPSAL----------
MLBr_00737|M.leprae_Br4923          -VERFMRDAKITQIYEGTNQIQRVVMSRALLR------------------
                                            :    *  *:.:: * ::..  *                   

TH_2543|M.thermoresistible__bu      ---
MAV_1878|M.avium_104                ---
Mb1969c|M.bovis_AF2122/97           ---
Rv1934c|M.tuberculosis_H37Rv        ---
Mvan_4006|M.vanbaalenii_PYR-1       GSN
MMAR_5049|M.marinum_M               ---
MUL_4125|M.ulcerans_Agy99           ---
MSMEG_6012|M.smegmatis_MC2_155      ---
MAB_0597|M.abscessus_ATCC_1997      ---
Mflv_1794|M.gilvum_PYR-GCK          ---
MLBr_00737|M.leprae_Br4923          ---