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M. avium 104 MAV_2619 (-)

annotation: acyl-CoA dehydrogenase domain-containing protein
coordinates: 2656120 - 2657292
length: 390

MDLDFTPDQLEFRDQVRTWLDENKPAEPRPRDDAGIREYDLAWQRTQAEGGWAGIAWPTEYGGKGLTLLQ
QLIWYEEYAARGFPGIDACFVGNSHAGPTLITRATDEQKSFHLPKILGGEVIWCQGFSEPDAGSDLAALR
TKAVVDGEDLVVSGQKLWTSFATVADYQELLVRTDNTGSKHKGITWVICDMSTPGIDVRPIETIEGGSEF
CEVFYDDVRIPLSNVVGDVGEGWSVAMATLSFERGTAFTANQVRLAKIIEDLIDYARDHVGPDGRRPAIA
DDDIARRLARARASVASLRALTYTNICEAMKTETPGPRGSIVKLMYAELAKEIGRLAMDVVGPASVRYSS
RWDVDGWVGYYYYSFSQAIGGGTSEIQRNIVGERVLGLPR

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. avium 104 MAV_2619 - - 100% (390) acyl-CoA dehydrogenase domain-containing protein
M. avium 104 MAV_1909 - 0.0 93.08% (390) acyl-CoA dehydrogenase domain-containing protein
M. avium 104 MAV_1268 - 1e-74 39.80% (402) acyl-CoA dehydrogenase domain-containing protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3590c fadE30 2e-71 39.39% (391) acyl-CoA dehydrogenase FADE30
M. gilvum PYR-GCK Mflv_1481 - 1e-70 38.92% (388) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3560c fadE30 2e-71 39.39% (391) acyl-CoA dehydrogenase FADE30
M. leprae Br4923 MLBr_00737 fadE25 2e-20 27.35% (340) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_0597 - 2e-74 39.28% (387) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_5049 fadE30 6e-69 38.87% (391) acyl-CoA dehydrogenase FadE30
M. smegmatis MC2 155 MSMEG_5619 - 9e-70 41.67% (396) acyl-CoA dehydrogenase domain-containing protein
M. thermoresistible (build 8) TH_4120 - 2e-75 41.71% (386) PUTATIVE putative acyl-CoA dehydrogenase domain protein
M. ulcerans Agy99 MUL_4125 fadE30 8e-68 38.36% (391) acyl-CoA dehydrogenase FadE30
M. vanbaalenii PYR-1 Mvan_5285 - 6e-71 40.26% (390) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MAV_2619|M.avium_104                ----------MDLDFTPD-QLEFRDQVRTWLDENKP---AEPRPRD----
MSMEG_5619|M.smegmatis_MC2_155      ------------MTHPEN-LDDFRATVRDWCAAHVP---KDWRAAQTGVS
TH_4120|M.thermoresistible__bu      -----VNDRDYGVALTDA-DRAFRDEVREFLASSLT---PDLLSRDGG--
MMAR_5049|M.marinum_M               --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
MUL_4125|M.ulcerans_Agy99           --------------MQDV--EEFRAEVRGWLAANLVGEFATLKGLGGPGR
Mb3590c|M.bovis_AF2122/97           --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
Rv3560c|M.tuberculosis_H37Rv        --------------MQDV--EEFRAQVRGWLADNLAGEFAALKGLGGPGR
Mflv_1481|M.gilvum_PYR-GCK          --------------MIEV--QKFRAEVRDWLAENLVGDFAALKGLGGPGR
Mvan_5285|M.vanbaalenii_PYR-1       --------------MIEV--QEFRAEVRDWLAENLVGEYAALKGLGGPGR
MAB_0597|M.abscessus_ATCC_1997      MVESQVSPAPAGEPMSEMSDDQVRTEIREWLAENLVGEFAELKGLGGPGS
MLBr_00737|M.leprae_Br4923          ----------MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAAD
                                                          .:   .                      

MAV_2619|M.avium_104                DAGIREYDLAWQRTQAEGGWAGIAWPTEYGGKGLTLLQQLIWYEEYAARG
MSMEG_5619|M.smegmatis_MC2_155      DDEFAAFQKAWFAELHSAGYAVPHWPAEWGG-GMSVPQQIVLYSELAAHD
TH_4120|M.thermoresistible__bu      ETARLDRLRRWQGLLYDAGLAAISWPTEYGGRAATPTQQLIFNTEMAAAR
MMAR_5049|M.marinum_M               EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
MUL_4125|M.ulcerans_Agy99           EHEAFEERRAWNQHLAAAGLTCLGWPVEHGGRGLSTAHRVAFYEEYARAD
Mb3590c|M.bovis_AF2122/97           EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
Rv3560c|M.tuberculosis_H37Rv        EHEAFEERRAWNQRLAAAGLTCLGWPEEHGGRGLSTAHRVAFYEEYARAD
Mflv_1481|M.gilvum_PYR-GCK          EHEAFEERLAWNQHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
Mvan_5285|M.vanbaalenii_PYR-1       EHEAFEERLAWNRHLAAAGLTCLGWPEEHGGRGLSVAHRVAFYEEYAKAN
MAB_0597|M.abscessus_ATCC_1997      EHEAFEERLAWNRHLAAAGWTCLGWPVEHGGRGATVSQRVIFYEEYARAE
MLBr_00737|M.leprae_Br4923          VDQRARFPEEALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVD
                                                     .*      * * ** .           * *   

MAV_2619|M.avium_104                FPGIDACFVGNSHAGPTLITRATDEQKSFHLPKILGGEVIWCQGFSEPDA
MSMEG_5619|M.smegmatis_MC2_155      APRLVLAFVGIHHAASTLLAAGTDAQRNRHLPAILDGE-IWVQGFSEPEA
TH_4120|M.thermoresistible__bu      AP-EPINRSAINQLGPTIIQWGTDEQRAYYLPRILSAEDVWCQGFSEPEA
MMAR_5049|M.marinum_M               AP-DKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGA
MUL_4125|M.ulcerans_Agy99           AP-DKVNHFGEELLGPTLIAFGTPEQQQRFLPRILDVTELWCQGYSEPGA
Mb3590c|M.bovis_AF2122/97           AP-DKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGA
Rv3560c|M.tuberculosis_H37Rv        AP-DKVNHFGEELLGPTLIAFGTPQQQRRFLPRIRDVTELWCQGYSEPGA
Mflv_1481|M.gilvum_PYR-GCK          AP-DKVNHLGEELLGPTLIAYGTPEQQQRFLPRILDVTELWSQGYSEPGA
Mvan_5285|M.vanbaalenii_PYR-1       AP-DKVNHLGEELLGPTLIAYGTPEQQQRFLPKILDVTELWSQGYSEPGA
MAB_0597|M.abscessus_ATCC_1997      AP-HKVNHLGEELLGPTLIAYGTPEQQQRFLPAIRDVTELWCQGYSEPGA
MLBr_00737|M.leprae_Br4923          AS-ASLIPAVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREA
                                     .               ::  .:   :   ** :     :   . **  *

MAV_2619|M.avium_104                GSDLAALRTKAVVD--GEDLVVSGQKLWTSFATVADYQELLVRTDNTGSK
MSMEG_5619|M.smegmatis_MC2_155      GSDLASLRTTARAE--GDTFVVNGQKLWASGAMYADWCLLLARTDPNAPK
TH_4120|M.thermoresistible__bu      GSDLASLKTRAVID--GDELVITGQKIWTSKATYANRIYLLARTDPDAPK
MMAR_5049|M.marinum_M               GSDLANVATTAELD--GDQWVINGQKVWTSLAHLSQWCFVVARTEKGSKR
MUL_4125|M.ulcerans_Agy99           GSDLANVATTAELD--GDQWVINGQKVWTSLAHLSQWCFVVARTEKGSKR
Mb3590c|M.bovis_AF2122/97           GSDLASVATTAELD--GDQWVINGQKVWTSLAHLSQWCFVLARTEKGSQR
Rv3560c|M.tuberculosis_H37Rv        GSDLASVATTAELD--GDQWVINGQKVWTSLAHLSQWCFVLARTEKGSQR
Mflv_1481|M.gilvum_PYR-GCK          GSDLANVSTTATLD--GDEWVINGQKVWTSLAHWAQWCFVVARTEKGSKR
Mvan_5285|M.vanbaalenii_PYR-1       GSDLANVSTTAVLDEEGRQWHINGQKVWTSLAHWAQWCFVVARTEKGSKR
MAB_0597|M.abscessus_ATCC_1997      GSDLANVSTSAVLD--GGDWVINGQKVWTSLALQSQWCFVVARTEPGSSR
MLBr_00737|M.leprae_Br4923          GSDAASMRTRAKAD--GDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGA
                                    *** * : * *  :  *    :.* * * : .  :    ::. *:     

MAV_2619|M.avium_104                HKGITWVICDMSTPGIDVRPIETIEGG--SEFCEVFYDDVRIPLSNVVGD
MSMEG_5619|M.smegmatis_MC2_155      RHGISYFMMDMKTPGVDVRPIRNAVGD--SHFCEIFLNDVVIPSANLVGP
TH_4120|M.thermoresistible__bu      REGISYILADLNTPGIEVRPIRQITGA--SEFCEVFLDSVRVPLANVLGP
MMAR_5049|M.marinum_M               HAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTDADLVVGA
MUL_4125|M.ulcerans_Agy99           HAGLSYLLVPLDQPSVQIRPIVQITGT--AEFNEVFFDDARTDADLVVGA
Mb3590c|M.bovis_AF2122/97           HAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTDADLVVGA
Rv3560c|M.tuberculosis_H37Rv        HAGLSYLLVPLDQPGVQIRPIVQITGT--AEFNEVFFDDARTDADLVVGA
Mflv_1481|M.gilvum_PYR-GCK          HAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDARTAADLVVGE
Mvan_5285|M.vanbaalenii_PYR-1       HAGLSYLLVPLQQPGVEIRPIIQLTGD--SEFNEVFFDDARTDADLVVGE
MAB_0597|M.abscessus_ATCC_1997      HKGLSYLLVPLDQPGVEIRPIIQLTGT--SEFNEVFFDNARTSADLVVGE
MLBr_00737|M.leprae_Br4923          N-GISAFIVHKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGE
                                    . *:: .:   .  ...: *     *   :   *:: :.       ::* 

MAV_2619|M.avium_104                VGEGWSVAMATLSFERGTAFTANQVRLAKIIEDLIDYARDHVGPDGRRPA
MSMEG_5619|M.smegmatis_MC2_155      VNKGWQVAQATLGAERGMTMLELAERLG---NAGFRWLVDACSP------
TH_4120|M.thermoresistible__bu      LHGGWRVAKSTLGYER--VGQSRTHRIERRLGILVKMAQEPNALTDSG--
MMAR_5049|M.marinum_M               PGDGWRVAMGTLTFERGVSTLGQQIVYARELSDLAALARRTGAA------
MUL_4125|M.ulcerans_Agy99           PGDGWRVAMGTLTFERGVSTLGQQIVYARELSDLAALARRTGAA------
Mb3590c|M.bovis_AF2122/97           PGDGWRVAMATLTFERGVSTLGQQIVYARELSNLVELARRTAAA------
Rv3560c|M.tuberculosis_H37Rv        PGDGWRVAMATLTFERGVSTLGQQIVYARELSNLVELARRTAAA------
Mflv_1481|M.gilvum_PYR-GCK          PGDGWRVAMGTLTFERGVSTLGQQIRYAREHSNLVELAEKTGAA------
Mvan_5285|M.vanbaalenii_PYR-1       PGDGWRVAMGTLTFERGVSTLGQQIRYAREHSNLVELAKRTGAA------
MAB_0597|M.abscessus_ATCC_1997      PGDGWRVAMGTLTFERGVSTLGNQITYARELSRLAELAKSNGAA------
MLBr_00737|M.leprae_Br4923          PGTGFKTALATLDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFG--ESI
                                       *: .* .**   *                                  

MAV_2619|M.avium_104                IADDDIARRLARARASVASLRALTYTNICEAMKTETPGPR-GSIVKLMYA
MSMEG_5619|M.smegmatis_MC2_155      VDDPVVADRLAQFEIELTGLRGLCR-DLVERSETGEAGPADASIVKLYYS
TH_4120|M.thermoresistible__bu      FDDSYVADRIVRYAAQVEALRQIAAQATAAGVRGVAPGPE-ASVAKLLTS
MMAR_5049|M.marinum_M               -DDPFIRERLTRAWTGLRAMRSYALATMD----VEQPGQD--NVSKLLWA
MUL_4125|M.ulcerans_Agy99           -DDPFIREHLTRAWTGLRAMRSYALATMD----VEQPGQD--NVSKLLWA
Mb3590c|M.bovis_AF2122/97           -DDPLIRERLTRAWTGLRAMRSYALATMEGPA-VEQPGQD--NVSKLLWA
Rv3560c|M.tuberculosis_H37Rv        -DDPLIRERLTRAWTGLRAMRSYALATMEGPA-VEQPGQD--NVSKLLWA
Mflv_1481|M.gilvum_PYR-GCK          -DDPLIRERLVRSWAGLKAMRSYALATMD----VEKPGQD--NISKLLWA
Mvan_5285|M.vanbaalenii_PYR-1       -DDPLIRERLTRSWAGLKAMRSYALATMD----VEQPGMD--NVSKLLWA
MAB_0597|M.abscessus_ATCC_1997      -DDPAIRERLAQAYVGMRTMRAYALATMD----EERPGQD--NVSKLLWA
MLBr_00737|M.leprae_Br4923          STFQSIQFMLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFAS
                                         :   :.     :   *                        *   :

MAV_2619|M.avium_104                ELAKEIGRLAMDVVGP-----ASVRYSSRWDVDGWVGYYYYSFSQAIGGG
MSMEG_5619|M.smegmatis_MC2_155      ELLQRMTDFGAQIAGLPAHTVLTKPASSGWESGAWMLDFIGSWEWTIPGG
TH_4120|M.thermoresistible__bu      EVDQSMANFGVELAGAPG--VLERGSPGAAKRGNVAASYLLMRAATFGAG
MMAR_5049|M.marinum_M               NWHRSLGELAMDVIGKPG------LTLADGEFDEWQRLFLFTRADTIYGG
MUL_4125|M.ulcerans_Agy99           NWHRSLGELAMDVIGKPG------LTLADGEFDEWQRLFLFTRADTIYGG
Mb3590c|M.bovis_AF2122/97           NWHRNLGELAMDVIGKPG------MTMPDGEFDEWQRLYLFTRADTIYGG
Rv3560c|M.tuberculosis_H37Rv        NWHRNLGELAMDVIGKPG------MTMPDGEFDEWQRLYLFTRADTIYGG
Mflv_1481|M.gilvum_PYR-GCK          NWHRELGEIAMDIEGAAG------LTLPDGEFSEWQRLYLFSRSDTIYGG
Mvan_5285|M.vanbaalenii_PYR-1       NWHRELGEIAMDVQGMAG------LTLPGGEFDEWQRLYLFSRSDTIYGG
MAB_0597|M.abscessus_ATCC_1997      NWHRDLGELAMEIIGTST------LLTNAGEMDEWQRLFLFSRADTIYGG
MLBr_00737|M.leprae_Br4923          DIAMEVTTDAVQLFGGAG-------YTSDFPVERFMRDAKIT---QIYEG
                                    :    :   . :: *                               :  *

MAV_2619|M.avium_104                TSEIQRNIVGERVLGLPR-----
MSMEG_5619|M.smegmatis_MC2_155      ASEIQRTIIGERGLGLPREPSAV
TH_4120|M.thermoresistible__bu      TSEIQRNVIAERLLGLPRDN---
MMAR_5049|M.marinum_M               SNEIQRNIIAERVLGLPREAKG-
MUL_4125|M.ulcerans_Agy99           SNEIQRNIIAERVLGLPREAKG-
Mb3590c|M.bovis_AF2122/97           SNEIQRNIIAERVLGLPREAKG-
Rv3560c|M.tuberculosis_H37Rv        SNEIQRNIIAERVLGLPREAKG-
Mflv_1481|M.gilvum_PYR-GCK          SNEIQRNIIAERVLGLPREARH-
Mvan_5285|M.vanbaalenii_PYR-1       SNEIQRNIIAERVLGLPREAKG-
MAB_0597|M.abscessus_ATCC_1997      SNEIQRNIISERVLGLPREAR--
MLBr_00737|M.leprae_Br4923          TNQIQRVVMSRALLR--------
                                    :.:*** ::..  *

species	id	gene	e-value	identity (len)	annotation
M. avium 104	MAV_2619	-	-	100% (390)	acyl-CoA dehydrogenase domain-containing protein
M. avium 104	MAV_1909	-	0.0	93.08% (390)	acyl-CoA dehydrogenase domain-containing protein
M. avium 104	MAV_1268	-	1e-74	39.80% (402)	acyl-CoA dehydrogenase domain-containing protein