For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTATVDGATGLLDAALVEDIRAHAAVLDRGQDSARRSFTALGEAGVLGIGAPGNRDGRLPVMAEVIRSIS GICMSTGFSLWAHRMTVEYLLTAATPFSAVAVRPLLRGSVLGVTGMAAAFKEAAGCGSMELTATPVAGGY RVSGPIRWASNLYPDSTMVTAVRTEAGERLIVAVPLDTPGVILGEHFDLLALGSTASSYLNFDGAHIADE QVLSRDFDGFLQAVRPTFLVLQSAMCLGLSRTAVRQAGFGLGGVNAVFRADVEAITEKLGAAEETLAKLA AAVGGPAAPSKKELLSLRLAAAELAAASADVEIRTAGGKGYASRTSASRRYREAAFIPVQSPSEAQLRWE LAGCG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2487 | - | - | 100% (355) | NtrC protein |
| M. avium 104 | MAV_4768 | - | 8e-10 | 26.43% (333) | long-chain specific acyl-CoA dehydrogenase |
| M. avium 104 | MAV_2668 | - | 3e-06 | 22.29% (323) | acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1706 | fadE16 | 9e-12 | 24.05% (341) | acyl-CoA dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4943 | - | 2e-09 | 23.99% (321) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv1679 | fadE16 | 9e-12 | 24.05% (341) | acyl-CoA dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2460 | - | 6e-66 | 42.26% (336) | hypothetical protein MAB_2460 |
| M. marinum M | MMAR_2998 | - | 1e-131 | 66.38% (354) | hypothetical protein MMAR_2998 |
| M. smegmatis MC2 155 | MSMEG_4519 | - | 8e-55 | 37.97% (345) | NrtC protein |
| M. thermoresistible (build 8) | TH_4603 | - | 3e-09 | 22.63% (327) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_2239 | - | 1e-126 | 64.35% (359) | hypothetical protein MUL_2239 |
| M. vanbaalenii PYR-1 | Mvan_5885 | - | 1e-08 | 21.85% (325) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2998|M.marinum_M -------MTATVDAATDLLHSELLAEIRAHASALDRGDGTARRSFPGLGA
MUL_2239|M.ulcerans_Agy99 -------MTATVDAATDLLHSELLAEIRAHASALDRGDGTARRSFPGLGA
MAV_2487|M.avium_104 -------MTATVDGATGLLDAALVEDIRAHAAVLDRGQDSARRSFTALGE
MAB_2460|M.abscessus_ATCC_1997 -------MAREIDDELER----VVDEVARRAAALDADQTDVRVDIAALGA
MSMEG_4519|M.smegmatis_MC2_155 ------MTAMLADSALDR----VARTVAARAAELDEQRTDVRTDLAELGR
Mb1706|M.bovis_AF2122/97 -----MATPGVVQEVVSVAAEHAERVDT--------DCAFPAEAVDALRK
Rv1679|M.tuberculosis_H37Rv -----MATPGVVQEVVSVAAEHAERVDT--------DCAFPAEAVDALRK
Mvan_5885|M.vanbaalenii_PYR-1 -----MYSTEALNHVISVAAASADQVDA--------EGAYPAAAVDALRG
Mflv_4943|M.gilvum_PYR-GCK MPVDRLLPTDDARDLVELARQIADKVLDPIVDRHEKDETYPEGVFATLGE
TH_4603|M.thermoresistible__bu MAVDRLLPSQEAAELIELTREIADKVLDPIVDRHEKDETYPEGVFEQLGA
. . *
MMAR_2998|M.marinum_M VGLLGLGAPGNSDGCLPQMAEVIS-----VISGECMSTGFSVWASRMAVE
MUL_2239|M.ulcerans_Agy99 VGLLGLGAPGNSDGCLPQMAEAISVISISVISGECMSTGFSVWASRMAVE
MAV_2487|M.avium_104 AGVLGIGAPGNRDGRLPVMAEVIR-----SISGICMSTGFSLWAHRMTVE
MAB_2460|M.abscessus_ATCC_1997 QGLFHAGGVGT---DLAPMVRTIE-----RVATGSLAVGFSAWAHRMAIE
MSMEG_4519|M.smegmatis_MC2_155 EGLLDL--------DLPGMVRVID-----EVSAHSLAVGFSTWAHHMSLR
Mb1706|M.bovis_AF2122/97 TGLLGLVLPREIGGMGSGPVEFTEVVA--QLSAACGSTAMIYLMHMAAAV
Rv1679|M.tuberculosis_H37Rv TGLLGLVLPREIGGMGSGPVEFTEVVA--QLSAACGSTAMIYLMHMAAAV
Mvan_5885|M.vanbaalenii_PYR-1 SGLLGLVVPEEAGGLGAGPQQFVDVVG--GLAAACGSTAMVYLMHTAAAV
Mflv_4943|M.gilvum_PYR-GCK AGLLSLPYPEEWGGGGQPYEVYLQVLE--ELAARWAAVAVAVSVHSLSCH
TH_4603|M.thermoresistible__bu AGLLSLPQPEEWGGGGQPYEVYLQVLE--EIAARWASVAVAVSVHSLSSH
*:: :: :... :
MMAR_2998|M.marinum_M YLLTA-ATEYSLAVVGPLLAGAALGISGMAAAFKEAAGCGDLELTA-RPV
MUL_2239|M.ulcerans_Agy99 YLLTA-ATEYSLAVVGPLLAGAALGISGMAAAFKEAAGCADLELTA-RPV
MAV_2487|M.avium_104 YLLTA-ATPFSAVAVRPLLRGSVLGVTGMAAAFKEAAGCGSMELTA-TPV
MAB_2460|M.abscessus_ATCC_1997 YVSLA-AADFRAEHLAELTGGHRPGVTAMAAGLKQAAGLGEVPLRA-TNQ
MSMEG_4519|M.smegmatis_MC2_155 YLNAS-STGGFDEQISALAAARKIGVTAMAAGLKQIAGLGQVPVTG-DND
Mb1706|M.bovis_AF2122/97 TVAAS-PPPGLPDLLADMASGKQLGTLAFSEPGSRSHFWAPVSTA--SAD
Rv1679|M.tuberculosis_H37Rv TVAAS-PPPGLPDLLADMASGKQLGTLAFSEPGSRSHFWAPVSTA--SAD
Mvan_5885|M.vanbaalenii_PYR-1 TVAAA-PPPGMPEMLSAMASGNALGTLAFSEKGSRSHFWAPVSTAALSDD
Mflv_4943|M.gilvum_PYR-GCK PLMSFGSDEQRQRWLPDMLGGSTIGAYSLSEPQAGSDAAALTCRA--TAV
TH_4603|M.thermoresistible__bu PLLVFGTEEQKKRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAA--TPT
: . : : . * .:: .
MMAR_2998|M.marinum_M TGGYQLSGSIRWASNLYQDSVLVTAART---ERGEKLIVALPLATPGVAV
MUL_2239|M.ulcerans_Agy99 TGGYQLSGSIRWASNLYQDSVLVTAART---ERGEELIVALPLATPGVAV
MAV_2487|M.avium_104 AGGYRVSGPIRWASNLYPDSTMVTAVRT---EAGERLIVAVPLDTPGVIL
MAB_2460|M.abscessus_ATCC_1997 GDGLSISGPIRWASNVFPDALMVVPACG---ADGTTYVVAIEVCANGVRI
MSMEG_4519|M.smegmatis_MC2_155 GSDLIVSGPIRWATNVFPDALMVLPVR----VGEHTVVVAVGTGDDGVTV
Mb1706|M.bovis_AF2122/97 GDGIAVRADKSWVTSAGFADVYVVSVGSADGAAGDVDLYAVPADTPGLRV
Rv1679|M.tuberculosis_H37Rv GDGIAVRADKSWVTSAGFADVYVVSVGSADGAAGDVDLYAVPADTPGLRV
Mvan_5885|M.vanbaalenii_PYR-1 GDTVKLRADKSWVTSAGYADIYIVSAGSTSGVAGEVDLYALPRSGEGLSV
Mflv_4943|M.gilvum_PYR-GCK DGGYRITGSKAWITHGGIADFYNLFARTGEGSQG-ISCFLVPRDTEGLTF
TH_4603|M.thermoresistible__bu DGGYVINGSKSWITHGGKADFYTLFARTGEGSRG-VSCFLVPADQPGLSF
. : . * : . : *: .
MMAR_2998|M.marinum_M GDHFELLAMGSTASSQLELQDVYVASEQVLSTDCGGFLDAVR---PTFLV
MUL_2239|M.ulcerans_Agy99 GDHFELLAMASTASSQLELQDVYVASEQVLSTDCGGFLDAVR---PTFLV
MAV_2487|M.avium_104 GEHFDLLALGSTASSYLNFDGAHIADEQVLSRDFDGFLQAVR---PTFLV
MAB_2460|M.abscessus_ATCC_1997 QRPPDLMALTATASTSLHLDDVRVPMEHVISTDLQGFVRRIR---PAFLL
MSMEG_4519|M.smegmatis_MC2_155 DPAPPLTALGATASTSLHLNEVRVAADQVLATDLAAFVARIR---PAFLL
Mb1706|M.bovis_AF2122/97 AGTFTGMGLRGN-ASAPMAVDIRIPDSYRLGEAGGGFGIMMQTVLPWFNL
Rv1679|M.tuberculosis_H37Rv AGTFTGMGLRGN-ASAPMAVDIRIPDSYRLGEAGGGFGIMMQTVLPWFNL
Mvan_5885|M.vanbaalenii_PYR-1 VAPFAGMGLRGN-ASSPMTVDATIPVASRLGAQAAGFGLLMETVLPWFNL
Mflv_4943|M.gilvum_PYR-GCK GKPEEKMGLHAVPTTAAHYDDANLDSDRRIGTEGQGLQIAFS-ALDSGRL
TH_4603|M.thermoresistible__bu GKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIAFS-ALDSGRL
.: . :: : :. .: . :
MMAR_2998|M.marinum_M LQSAMCIGLARTALAQSRIALAGVN-----------SVYVPDLDLIAERL
MUL_2239|M.ulcerans_Agy99 LQSGMCIGLARTALAQSRIALAGVN-----------SVYAPDFDLIAERL
MAV_2487|M.avium_104 LQSAMCLGLSRTAVRQAGFGLGGVN-----------AVFRADVEAITEKL
MAB_2460|M.abscessus_ATCC_1997 LQTAFCSGVSVAALEGARAAHGIIA-----------AQFSTELDDITRRS
MSMEG_4519|M.smegmatis_MC2_155 LQTAFCVGITRAALTAATEAHTGPL-----------ARFGAELDDAATRA
Mb1706|M.bovis_AF2122/97 GNAAVSLGLATAATGAAVKHVGTARLEHLGGSLAELPTIRAQIARMGTTL
Rv1679|M.tuberculosis_H37Rv GNAAVSLGLATAATGAAVKHVGTARLEHLGGSLAELPTIRAQIARMGTTL
Mvan_5885|M.vanbaalenii_PYR-1 GNAAVSLGLAGSAYVATIGHVSGARLEHRDEALSALPTIRAQIAKMGTTL
Mflv_4943|M.gilvum_PYR-GCK GIAAVAVGLAQAALDEAVAYSQER--TTFGRKIIDHQGLAFLLADMAAAV
TH_4603|M.thermoresistible__bu GIAAVATGLAQAALDEAVAYANER--TAFGRKIIDHQGLGFLLADMAAAV
:... *:: :* : .
MMAR_2998|M.marinum_M ALAESTLSGAAASVGTQRPAGRRELLSLRLSSAKIACASADLEIRVAGGK
MUL_2239|M.ulcerans_Agy99 ALAESTLSGAAASVGTQRPAGRRELLSLRLSSAKIACASADREIRVAGGK
MAV_2487|M.avium_104 GAAEETLAKLAAAVGGPAAPSKKELLSLRLAAAELAAASADVEIRTAGGK
MAB_2460|M.abscessus_ATCC_1997 HALRERLYTFAAVPSAPDIA---DLLRLRLDAAGLAGAASRLEVTLSGGA
MSMEG_4519|M.smegmatis_MC2_155 ADIRARLYGWASDPGTATVP---DLIRLRLDAAHAAVDVTRLELSLTGGV
Mb1706|M.bovis_AF2122/97 AAQKAYLEVAANSVSSPDDTTLTHVLGVKASVNDAALTITESAMRVCGGA
Rv1679|M.tuberculosis_H37Rv AAQKAYLEVAANSVSSPDDTTLTHVLGVKASVNDAALTITESAMRVCGGA
Mvan_5885|M.vanbaalenii_PYR-1 AAQRAYLRSAAASVSAPDEETLNHVLGIKASANDAALTITESAMRVCGGA
Mflv_4943|M.gilvum_PYR-GCK DSARATYLDAARRRDA-GLPYSRHASVAKLVATDAAMKVTTDAVQVLGGA
TH_4603|M.thermoresistible__bu ATARATYLDAARRRDQ-GRPYSQQASIAKLTATDAAMKVTTDAVQVFGGV
. * . . : * : : **
MMAR_2998|M.marinum_M GYASRTPTNRRYREAAFLPVQSPSEAQLRWELDRCR------
MUL_2239|M.ulcerans_Agy99 GYASRTPTNRRYREAAFLPVQSPSEAQLRWELDRCR------
MAV_2487|M.avium_104 GYASRTSASRRYREAAFIPVQSPSEAQLRWELAGCG------
MAB_2460|M.abscessus_ATCC_1997 GYALGTPANRRFREAAFLPIQSPSEGQLRWELKQYE------
MSMEG_4519|M.smegmatis_MC2_155 GYTLGSAANRRFREAAFLPVQSPSEGQLRWELTRYE------
Mb1706|M.bovis_AF2122/97 AFSKHLPIERAFRDARAGSVMAPTADALYDFYGRAVTGLPLF
Rv1679|M.tuberculosis_H37Rv AFSKHLPIERAFRDARAGSVMAPTADALYDFYGRAVTGLPLF
Mvan_5885|M.vanbaalenii_PYR-1 AFSKHLPIERNFRDARAGAVMAPTADVLYDFYGKAVTGLPLF
Mflv_4943|M.gilvum_PYR-GCK GYTRDYRVERYMREAKITQIFEGTNQIQRLVISRHLTRG---
TH_4603|M.thermoresistible__bu GYTRDYRVERYMREAKIMQIFEGTNQIQRLVIARGLTR----
.:: .* *:* : :