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MAREIDDELERVVDEVARRAAALDADQTDVRVDIAALGAQGLFHAGGVGTDLAPMVRTIERVATGSLAVG FSAWAHRMAIEYVSLAAADFRAEHLAELTGGHRPGVTAMAAGLKQAAGLGEVPLRATNQGDGLSISGPIR WASNVFPDALMVVPACGADGTTYVVAIEVCANGVRIQRPPDLMALTATASTSLHLDDVRVPMEHVISTDL QGFVRRIRPAFLLLQTAFCSGVSVAALEGARAAHGIIAAQFSTELDDITRRSHALRERLYTFAAVPSAPD IADLLRLRLDAAGLAGAASRLEVTLSGGAGYALGTPANRRFREAAFLPIQSPSEGQLRWELKQYE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2460 | - | - | 100% (345) | hypothetical protein MAB_2460 |
| M. abscessus ATCC 19977 | MAB_4538c | - | 9e-13 | 26.93% (375) | putative acyl-CoA dehydrogenase FadE |
| M. abscessus ATCC 19977 | MAB_2081 | - | 4e-06 | 25.84% (178) | acyl CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1706 | fadE16 | 3e-08 | 22.19% (356) | acyl-CoA dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4943 | - | 2e-07 | 24.44% (360) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv1679 | fadE16 | 3e-08 | 22.19% (356) | acyl-CoA dehydrogenase |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 1e-05 | 23.84% (344) | putative acyl-CoA dehydrogenase |
| M. marinum M | MMAR_2998 | - | 1e-59 | 40.24% (333) | hypothetical protein MMAR_2998 |
| M. avium 104 | MAV_2487 | - | 5e-66 | 42.26% (336) | NtrC protein |
| M. smegmatis MC2 155 | MSMEG_4519 | - | 1e-95 | 55.00% (340) | NrtC protein |
| M. thermoresistible (build 8) | TH_2782 | - | 5e-06 | 23.66% (355) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_2239 | - | 3e-57 | 38.46% (338) | hypothetical protein MUL_2239 |
| M. vanbaalenii PYR-1 | Mvan_5885 | - | 3e-08 | 21.75% (354) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
TH_2782|M.thermoresistible__bu MPDY-----LTTGNLPDHYAELAGTVRDFAQSVVAPVAAKHDQERSFPYE
Mflv_4943|M.gilvum_PYR-GCK -------MPVDRLLPTDDARDLVELARQIADKVLDPIVDRHEKDETYPEG
Mb1706|M.bovis_AF2122/97 --------------------MATPGVVQEVVSVAAEHAERVDTDCAFPAE
Rv1679|M.tuberculosis_H37Rv --------------------MATPGVVQEVVSVAAEHAERVDTDCAFPAE
Mvan_5885|M.vanbaalenii_PYR-1 --------------------MYSTEALNHVISVAAASADQVDAEGAYPAA
MAB_2460|M.abscessus_ATCC_1997 --------------MAREIDDELER----VVDEVARRAAALDADQTDVRV
MSMEG_4519|M.smegmatis_MC2_155 -------------MTAMLADSALDR----VARTVAARAAELDEQRTDVRT
MMAR_2998|M.marinum_M --------------MTATVDAATDLLHSELLAEIRAHASALDRGDGTARR
MUL_2239|M.ulcerans_Agy99 --------------MTATVDAATDLLHSELLAEIRAHASALDRGDGTARR
MAV_2487|M.avium_104 --------------MTATVDGATGLLDAALVEDIRAHAAVLDRGQDSARR
. :
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
TH_2782|M.thermoresistible__bu VVAAMGEMGLFGLPFPEEYGGMGGDYFALCLALEELGKVDQSVAITLEAG
Mflv_4943|M.gilvum_PYR-GCK VFATLGEAGLLSLPYPEEWGGGGQPYEVYLQVLEELAARWAAVAVAVSVH
Mb1706|M.bovis_AF2122/97 AVDALRKTGLLGLVLPREIGGMGSGPVEFTEVVAQLSAACGSTAMIYLMH
Rv1679|M.tuberculosis_H37Rv AVDALRKTGLLGLVLPREIGGMGSGPVEFTEVVAQLSAACGSTAMIYLMH
Mvan_5885|M.vanbaalenii_PYR-1 AVDALRGSGLLGLVVPEEAGGLGAGPQQFVDVVGGLAAACGSTAMVYLMH
MAB_2460|M.abscessus_ATCC_1997 DIAALGAQGLFHAGGVGT---DLAPMVRTIE-----RVATGSLAVGFSAW
MSMEG_4519|M.smegmatis_MC2_155 DLAELGREGLLDL--------DLPGMVRVID-----EVSAHSLAVGFSTW
MMAR_2998|M.marinum_M SFPGLGAVGLLGLGAPGNSDGCLPQMAEVIS-----VISGECMSTGFSVW
MUL_2239|M.ulcerans_Agy99 SFPGLGAVGLLGLGAPGNSDGCLPQMAEAISVISISVISGECMSTGFSVW
MAV_2487|M.avium_104 SFTALGEAGVLGIGAPGNRDGRLPVMAEVIR-----SISGICMSTGFSLW
. : *. . :
MLBr_00737|M.leprae_Br4923 -KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTR
TH_2782|M.thermoresistible__bu VSLGAMPIYRFGTEEQKQRWLPELAAGKALGAFGLTEPGGGSDAGATRTT
Mflv_4943|M.gilvum_PYR-GCK -SLSCHPLMSFGSDEQRQRWLPDMLGGSTIGAYSLSEPQAGSDAAALTCR
Mb1706|M.bovis_AF2122/97 --MAAAVTVAASPPPGLPDLLADMASGKQLGTLAFSEPGSRSHFWAPVST
Rv1679|M.tuberculosis_H37Rv --MAAAVTVAASPPPGLPDLLADMASGKQLGTLAFSEPGSRSHFWAPVST
Mvan_5885|M.vanbaalenii_PYR-1 --TAAAVTVAAAPPPGMPEMLSAMASGNALGTLAFSEKGSRSHFWAPVST
MAB_2460|M.abscessus_ATCC_1997 AHRMAIEYVSLAAADFRAEHLAELTGGHRPGVTAMAAGLKQAAGLGEVPL
MSMEG_4519|M.smegmatis_MC2_155 AHHMSLRYLNASSTGGFDEQISALAAARKIGVTAMAAGLKQIAGLGQVPV
MMAR_2998|M.marinum_M ASRMAVEYLLTAATEYSLAVVGPLLAGAALGISGMAAAFKEAAGCGDLEL
MUL_2239|M.ulcerans_Agy99 ASRMAVEYLLTAATEYSLAVVGPLLAGAALGISGMAAAFKEAAGCADLEL
MAV_2487|M.avium_104 AHRMTVEYLLTAATPFSAVAVRPLLRGSVLGVTGMAAAFKEAAGCGSMEL
.. : : . .:: .
MLBr_00737|M.leprae_Br4923 A--KADGDDWILNGFKCWITNGGK--STWYTVMAVTDPDKGANGISAFIV
TH_2782|M.thermoresistible__bu A--RLDDGHWVINGSKQFITNSGTDITKLVTVTAVTGEVAGKKEISAIIV
Mflv_4943|M.gilvum_PYR-GCK A--TAVDGGYRITGSKAWITHGGI--ADFYNLFARTGE--GSQGISCFLV
Mb1706|M.bovis_AF2122/97 A--SADGDGIAVRADKSWVTSAGF--ADVYVVSVGSADG-AAGDVDLYAV
Rv1679|M.tuberculosis_H37Rv A--SADGDGIAVRADKSWVTSAGF--ADVYVVSVGSADG-AAGDVDLYAV
Mvan_5885|M.vanbaalenii_PYR-1 AALSDDGDTVKLRADKSWVTSAGY--ADIYIVSAGSTSG-VAGEVDLYAL
MAB_2460|M.abscessus_ATCC_1997 RA-TNQGDGLSISGPIRWASNVFP------DALMVVPACGADGTTYVVAI
MSMEG_4519|M.smegmatis_MC2_155 TG-DNDGSDLIVSGPIRWATNVFP------DALMVLPVR-VGEHTVVVAV
MMAR_2998|M.marinum_M TA-RPVTGGYQLSGSIRWASNLYQ------DSVLVTAARTERGEKLIVAL
MUL_2239|M.ulcerans_Agy99 TA-RPVTGGYQLSGSIRWASNLYQ------DSVLVTAARTERGEELIVAL
MAV_2487|M.avium_104 TA-TPVAGGYRVSGPIRWASNLYP------DSTMVTAVRTEAGERLIVAV
. : . : : :
MLBr_00737|M.leprae_Br4923 HKDDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTAL
TH_2782|M.thermoresistible__bu PVPTDGFTVEPAYHKVGWNASDTHPLSFDDVRVPEENLLGERGRGYANFL
Mflv_4943|M.gilvum_PYR-GCK PRDTEGLTFGKPEEKMGLHAVPTTAAHYDDANLDSDRRIGTEGQGLQIAF
Mb1706|M.bovis_AF2122/97 PADTPGLRVAGTFTGMGLRGNASAPMAVD-IRIPDSYRLGEAGGGFGIMM
Rv1679|M.tuberculosis_H37Rv PADTPGLRVAGTFTGMGLRGNASAPMAVD-IRIPDSYRLGEAGGGFGIMM
Mvan_5885|M.vanbaalenii_PYR-1 PRSGEGLSVVAPFAGMGLRGNASSPMTVD-ATIPVASRLGAQAAGFGLLM
MAB_2460|M.abscessus_ATCC_1997 EVCANGVRIQRPPDLMALTATASTSLHLDDVRVPMEHVISTDLQGFVRRI
MSMEG_4519|M.smegmatis_MC2_155 GTGDDGVTVDPAPPLTALGATASTSLHLNEVRVAADQVLATDLAAFVARI
MMAR_2998|M.marinum_M PLATPGVAVGDHFELLAMGSTASSQLELQDVYVASEQVLSTDCGGFLDAV
MUL_2239|M.ulcerans_Agy99 PLATPGVAVGDHFELLAMASTASSQLELQDVYVASEQVLSTDCGGFLDAV
MAV_2487|M.avium_104 PLDTPGVILGEHFDLLALGSTASSYLNFDGAHIADEQVLSRDFDGFLQAV
*. . . . : : : :. . .
MLBr_00737|M.leprae_Br4923 A-TLDHTRPTIGAQAVGIAQGALDAAIVYT--KDRKQFGESISTFQSIQF
TH_2782|M.thermoresistible__bu R-ILDEGRIAIAALSVGAAQGCVDESVKYA--KEREAFGRPIGANQAIAF
Mflv_4943|M.gilvum_PYR-GCK S-ALDSGRLGIAAVAVGLAQAALDEAVAYS--QERTTFGRKIIDHQGLAF
Mb1706|M.bovis_AF2122/97 QTVLPWFNLGNAAVSLGLATAATGAAVKHVGTARLEHLGGSLAELPTIRA
Rv1679|M.tuberculosis_H37Rv QTVLPWFNLGNAAVSLGLATAATGAAVKHVGTARLEHLGGSLAELPTIRA
Mvan_5885|M.vanbaalenii_PYR-1 ETVLPWFNLGNAAVSLGLAGSAYVATIGHVSGARLEHRDEALSALPTIRA
MAB_2460|M.abscessus_ATCC_1997 R---PAFLLLQTAFCSGVSVAALEGARAAHG-----------IIAAQFST
MSMEG_4519|M.smegmatis_MC2_155 R---PAFLLLQTAFCVGITRAALTAATEAHT-----------GPLARFGA
MMAR_2998|M.marinum_M R---PTFLVLQSAMCIGLARTALAQSRIALA-----------GVNSVYVP
MUL_2239|M.ulcerans_Agy99 R---PTFLVLQSGMCIGLARTALAQSRIALA-----------GVNSVYAP
MAV_2487|M.avium_104 R---PTFLVLQSAMCLGLSRTAVRQAGFGLG-----------GVNAVFRA
. . * : . :
MLBr_00737|M.leprae_Br4923 MLADMAMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTT
TH_2782|M.thermoresistible__bu KIARMEARAHTARTAYYDAAALMLAGKP-FKKQAAIAKMVASEAAMDNAR
Mflv_4943|M.gilvum_PYR-GCK LLADMAAAVDSARATYLDAARRRDAGLP-YSRHASVAKLVATDAAMKVTT
Mb1706|M.bovis_AF2122/97 QIARMGTTLAAQKAYLEVAANSVSSPDDTTLTHVLGVKASVNDAALTITE
Rv1679|M.tuberculosis_H37Rv QIARMGTTLAAQKAYLEVAANSVSSPDDTTLTHVLGVKASVNDAALTITE
Mvan_5885|M.vanbaalenii_PYR-1 QIAKMGTTLAAQRAYLRSAAASVSAPDEETLNHVLGIKASANDAALTITE
MAB_2460|M.abscessus_ATCC_1997 ELDDITRRSHALRERLYTFAAVPSAPDIA---DLLRLRLDAAGLAGAASR
MSMEG_4519|M.smegmatis_MC2_155 ELDDAATRAADIRARLYGWASDPGTATVP---DLIRLRLDAAHAAVDVTR
MMAR_2998|M.marinum_M DLDLIAERLALAESTLSGAAASVGTQRPAGRRELLSLRLSSAKIACASAD
MUL_2239|M.ulcerans_Agy99 DFDLIAERLALAESTLSGAAASVGTQRPAGRRELLSLRLSSAKIACASAD
MAV_2487|M.avium_104 DVEAITEKLGAAEETLAKLAAAVGGPAAPSKKELLSLRLAAAELAAASAD
. . * : * :
MLBr_00737|M.leprae_Br4923 DAVQLFGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR---
TH_2782|M.thermoresistible__bu DATQIFGGYGFINEFPVARHYRDSKILEIGEGTTEVQLMLIGRELGL---
Mflv_4943|M.gilvum_PYR-GCK DAVQVLGGAGYTRDYRVERYMREAKITQIFEGTNQIQRLVISRHLTRG--
Mb1706|M.bovis_AF2122/97 SAMRVCGGAAFSKHLPIERAFRDARAGSVMAPTADALYDFYGRAVTGLPL
Rv1679|M.tuberculosis_H37Rv SAMRVCGGAAFSKHLPIERAFRDARAGSVMAPTADALYDFYGRAVTGLPL
Mvan_5885|M.vanbaalenii_PYR-1 SAMRVCGGAAFSKHLPIERNFRDARAGAVMAPTADVLYDFYGKAVTGLPL
MAB_2460|M.abscessus_ATCC_1997 LEVTLSGGAGYALGTPANRRFREAAFLPIQSPSEGQLRWELKQYE-----
MSMEG_4519|M.smegmatis_MC2_155 LELSLTGGVGYTLGSAANRRFREAAFLPVQSPSEGQLRWELTRYE-----
MMAR_2998|M.marinum_M LEIRVAGGKGYASRTPTNRRYREAAFLPVQSPSEAQLRWELDRCR-----
MUL_2239|M.ulcerans_Agy99 REIRVAGGKGYASRTPTNRRYREAAFLPVQSPSEAQLRWELDRCR-----
MAV_2487|M.avium_104 VEIRTAGGKGYASRTSASRRYREAAFIPVQSPSEAQLRWELAGCG-----
** .: * *:: : :
MLBr_00737|M.leprae_Br4923 -
TH_2782|M.thermoresistible__bu -
Mflv_4943|M.gilvum_PYR-GCK -
Mb1706|M.bovis_AF2122/97 F
Rv1679|M.tuberculosis_H37Rv F
Mvan_5885|M.vanbaalenii_PYR-1 F
MAB_2460|M.abscessus_ATCC_1997 -
MSMEG_4519|M.smegmatis_MC2_155 -
MMAR_2998|M.marinum_M -
MUL_2239|M.ulcerans_Agy99 -
MAV_2487|M.avium_104 -