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TATVDAATDLLHSELLAEIRAHASALDRGDGTARRSFPGLGAVGLLGLGAPGNSDGCLPQMAEVISVISG ECMSTGFSVWASRMAVEYLLTAATEYSLAVVGPLLAGAALGISGMAAAFKEAAGCGDLELTARPVTGGYQ LSGSIRWASNLYQDSVLVTAARTERGEKLIVALPLATPGVAVGDHFELLAMGSTASSQLELQDVYVASEQ VLSTDCGGFLDAVRPTFLVLQSAMCIGLARTALAQSRIALAGVNSVYVPDLDLIAERLALAESTLSGAAA SVGTQRPAGRRELLSLRLSSAKIACASADLEIRVAGGKGYASRTPTNRRYREAAFLPVQSPSEAQLRWEL DRCR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2998 | - | - | 100% (355) | hypothetical protein MMAR_2998 |
| M. marinum M | MMAR_4532 | fadE13 | 6e-07 | 21.71% (350) | acyl-CoA dehydrogenase FadE13 |
| M. marinum M | MMAR_0368 | - | 6e-07 | 25.46% (216) | peptide synthetase Nrp (peptide synthase) |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1706 | fadE16 | 3e-12 | 23.90% (364) | acyl-CoA dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1884 | - | 3e-09 | 24.65% (353) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv1679 | fadE16 | 3e-12 | 23.90% (364) | acyl-CoA dehydrogenase |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2460 | - | 8e-60 | 40.24% (333) | hypothetical protein MAB_2460 |
| M. avium 104 | MAV_2487 | - | 1e-131 | 66.38% (354) | NtrC protein |
| M. smegmatis MC2 155 | MSMEG_4519 | - | 1e-54 | 38.62% (334) | NrtC protein |
| M. thermoresistible (build 8) | TH_4603 | - | 9e-09 | 23.08% (325) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_2239 | - | 0.0 | 96.39% (360) | hypothetical protein MUL_2239 |
| M. vanbaalenii PYR-1 | Mvan_5885 | - | 3e-11 | 22.41% (357) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1706|M.bovis_AF2122/97 ---------MATPGVVQE----VVSVAAEHAERVDTDCAFPAEAVDALRK
Rv1679|M.tuberculosis_H37Rv ---------MATPGVVQE----VVSVAAEHAERVDTDCAFPAEAVDALRK
Mvan_5885|M.vanbaalenii_PYR-1 ---------MYSTEALNH----VISVAAASADQVDAEGAYPAAAVDALRG
MMAR_2998|M.marinum_M -------MTATVDAATDLLHSELLAEIRAHASALDRGDGTARRSFPGLGA
MUL_2239|M.ulcerans_Agy99 -------MTATVDAATDLLHSELLAEIRAHASALDRGDGTARRSFPGLGA
MAV_2487|M.avium_104 -------MTATVDGATGLLDAALVEDIRAHAAVLDRGQDSARRSFTALGE
MAB_2460|M.abscessus_ATCC_1997 -------MAREIDDELER----VVDEVARRAAALDADQTDVRVDIAALGA
MSMEG_4519|M.smegmatis_MC2_155 ------MTAMLADSALDR----VARTVAARAAELDEQRTDVRTDLAELGR
TH_4603|M.thermoresistible__bu MAVDRLLPSQEAAELIELTREIADKVLDPIVDRHEKDETYPEGVFEQLGA
Mflv_1884|M.gilvum_PYR-GCK ---MSIWTTPERDDLRRTVRAFAEREVLPFADEWERAREIPRDLHRAAAA
. :
Mb1706|M.bovis_AF2122/97 TGLLGLVLPREIGGMGSGPVEFTEVVA--QLSAACGSTAMIYLMHMAAAV
Rv1679|M.tuberculosis_H37Rv TGLLGLVLPREIGGMGSGPVEFTEVVA--QLSAACGSTAMIYLMHMAAAV
Mvan_5885|M.vanbaalenii_PYR-1 SGLLGLVVPEEAGGLGAGPQQFVDVVG--GLAAACGSTAMVYLMHTAAAV
MMAR_2998|M.marinum_M VGLLGLGAPGNSDGCLPQMAEVIS-----VISGECMSTGFSVWASRMAVE
MUL_2239|M.ulcerans_Agy99 VGLLGLGAPGNSDGCLPQMAEAISVISISVISGECMSTGFSVWASRMAVE
MAV_2487|M.avium_104 AGVLGIGAPGNRDGRLPVMAEVIR-----SISGICMSTGFSLWAHRMTVE
MAB_2460|M.abscessus_ATCC_1997 QGLFHAGGVGT---DLAPMVRTIE-----RVATGSLAVGFSAWAHRMAIE
MSMEG_4519|M.smegmatis_MC2_155 EGLLDL--------DLPGMVRVID-----EVSAHSLAVGFSTWAHHMSLR
TH_4603|M.thermoresistible__bu AGLLSLPQPEEWGGGGQPYEVYLQVLE--EIAARWASVAVAVSVHSLSSH
Mflv_1884|M.gilvum_PYR-GCK AGLLGAGFPEEVGGDGGDGADAVVICEEMHESGCPGGVFASLFTSGIAVP
*:: : .. :
Mb1706|M.bovis_AF2122/97 TVAASPPP-GLPDLLADMASGKQLGTLAFSEPGSRSHFWAPVSTA--SAD
Rv1679|M.tuberculosis_H37Rv TVAASPPP-GLPDLLADMASGKQLGTLAFSEPGSRSHFWAPVSTA--SAD
Mvan_5885|M.vanbaalenii_PYR-1 TVAAAPPP-GMPEMLSAMASGNALGTLAFSEKGSRSHFWAPVSTAALSDD
MMAR_2998|M.marinum_M YLLTAATE-YSLAVVGPLLAGAALGISGMAAAFKEAAGCGDLELTA-RPV
MUL_2239|M.ulcerans_Agy99 YLLTAATE-YSLAVVGPLLAGAALGISGMAAAFKEAAGCADLELTA-RPV
MAV_2487|M.avium_104 YLLTAATP-FSAVAVRPLLRGSVLGVTGMAAAFKEAAGCGSMELTA-TPV
MAB_2460|M.abscessus_ATCC_1997 YVSLAAAD-FRAEHLAELTGGHRPGVTAMAAGLKQAAGLGEVPLRA-TNQ
MSMEG_4519|M.smegmatis_MC2_155 YLNASSTG-GFDEQISALAAARKIGVTAMAAGLKQIAGLGQVPVTG-DND
TH_4603|M.thermoresistible__bu PLLVFGTEEQKKRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAAT--PT
Mflv_1884|M.gilvum_PYR-GCK HMIASQDERLIDTYVRPTLRGENIGSLAITEPGGGSDVGHLTTRAV--RD
: : . * .::
Mb1706|M.bovis_AF2122/97 GDGIAVRADKSWVTSAGFADVYVVSVGSADGAAGDVDLYAVPADTPGLRV
Rv1679|M.tuberculosis_H37Rv GDGIAVRADKSWVTSAGFADVYVVSVGSADGAAGDVDLYAVPADTPGLRV
Mvan_5885|M.vanbaalenii_PYR-1 GDTVKLRADKSWVTSAGYADIYIVSAGSTSGVAGEVDLYALPRSGEGLSV
MMAR_2998|M.marinum_M TGGYQLSGSIRWASNLYQDSVLVTAARTERGEK---LIVALPLATPGVAV
MUL_2239|M.ulcerans_Agy99 TGGYQLSGSIRWASNLYQDSVLVTAARTERGEE---LIVALPLATPGVAV
MAV_2487|M.avium_104 AGGYRVSGPIRWASNLYPDSTMVTAVRTEAGER---LIVAVPLDTPGVIL
MAB_2460|M.abscessus_ATCC_1997 GDGLSISGPIRWASNVFPDALMVVPACGADGTT---YVVAIEVCANGVRI
MSMEG_4519|M.smegmatis_MC2_155 GSDLIVSGPIRWATNVFPDALMVLPVR-VGEHT---VVVAVGTGDDGVTV
TH_4603|M.thermoresistible__bu DGGYVINGSKSWITHGGKADFYTLFARTGEGSRG-VSCFLVPADQPGLSF
Mflv_1884|M.gilvum_PYR-GCK GDCFIVNGAKTYITSGVRADYVVTAARTGGPGAAGISLIVVDKGTPGFAV
. : . : : . : *. .
Mb1706|M.bovis_AF2122/97 AGTFTGMGLRGNASAPMAVD-IRIPDSYRLGEAGGGFGIMMQTVLPWFNL
Rv1679|M.tuberculosis_H37Rv AGTFTGMGLRGNASAPMAVD-IRIPDSYRLGEAGGGFGIMMQTVLPWFNL
Mvan_5885|M.vanbaalenii_PYR-1 VAPFAGMGLRGNASSPMTVD-ATIPVASRLGAQAAGFGLLMETVLPWFNL
MMAR_2998|M.marinum_M GDHFELLAMGSTASSQLELQDVYVASEQVLSTDCGGF---LDAVRPTFLV
MUL_2239|M.ulcerans_Agy99 GDHFELLAMASTASSQLELQDVYVASEQVLSTDCGGF---LDAVRPTFLV
MAV_2487|M.avium_104 GEHFDLLALGSTASSYLNFDGAHIADEQVLSRDFDGF---LQAVRPTFLV
MAB_2460|M.abscessus_ATCC_1997 QRPPDLMALTATASTSLHLDDVRVPMEHVISTDLQGF---VRRIRPAFLL
MSMEG_4519|M.smegmatis_MC2_155 DPAPPLTALGATASTSLHLNEVRVAADQVLATDLAAF---VARIRPAFLL
TH_4603|M.thermoresistible__bu GKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIAFSALD-SGRL
Mflv_1884|M.gilvum_PYR-GCK SRKLDKMGWRSSDTAELSYTDVRVPAANVVGAENTGF-LQIAAAFVSERV
. . :: : :. .: . :
Mb1706|M.bovis_AF2122/97 GNAAVSLGLATAATGAAVKHVGTARLEHLGGSLAELPTIRAQIARMGTTL
Rv1679|M.tuberculosis_H37Rv GNAAVSLGLATAATGAAVKHVGTARLEHLGGSLAELPTIRAQIARMGTTL
Mvan_5885|M.vanbaalenii_PYR-1 GNAAVSLGLAGSAYVATIGHVSGARLEHRDEALSALPTIRAQIAKMGTTL
MMAR_2998|M.marinum_M LQSAMCIGLARTALAQSRIALA-----------GVNSVYVPDLDLIAERL
MUL_2239|M.ulcerans_Agy99 LQSGMCIGLARTALAQSRIALA-----------GVNSVYAPDFDLIAERL
MAV_2487|M.avium_104 LQSAMCLGLSRTAVRQAGFGLG-----------GVNAVFRADVEAITEKL
MAB_2460|M.abscessus_ATCC_1997 LQTAFCSGVSVAALEGARAAHG-----------IIAAQFSTELDDITRRS
MSMEG_4519|M.smegmatis_MC2_155 LQTAFCVGITRAALTAATEAHT-----------GPLARFGAELDDAATRA
TH_4603|M.thermoresistible__bu GIAAVATGLAQAALDEAVAYAN--ERTAFGRKIIDHQGLGFLLADMAAAV
Mflv_1884|M.gilvum_PYR-GCK GLAAQAYSSAQRCLDLTVEWCR--NRQTFGKPLIARQTVQSTLAEMARRI
:. . . : . : .
Mb1706|M.bovis_AF2122/97 AAQKAYLEVAANSVSSPDDTTLTHVLGVKASVNDAALTITESAMRVCGGA
Rv1679|M.tuberculosis_H37Rv AAQKAYLEVAANSVSSPDDTTLTHVLGVKASVNDAALTITESAMRVCGGA
Mvan_5885|M.vanbaalenii_PYR-1 AAQRAYLRSAAASVSAPDEETLNHVLGIKASANDAALTITESAMRVCGGA
MMAR_2998|M.marinum_M ALAESTLSGAAASVGTQRPAGRRELLSLRLSSAKIACASADLEIRVAGGK
MUL_2239|M.ulcerans_Agy99 ALAESTLSGAAASVGTQRPAGRRELLSLRLSSAKIACASADREIRVAGGK
MAV_2487|M.avium_104 GAAEETLAKLAAAVGGPAAPSKKELLSLRLAAAELAAASADVEIRTAGGK
MAB_2460|M.abscessus_ATCC_1997 HALRERLYTFAAVPSAPDIA---DLLRLRLDAAGLAGAASRLEVTLSGGA
MSMEG_4519|M.smegmatis_MC2_155 ADIRARLYGWASDPGTATVP---DLIRLRLDAAHAAVDVTRLELSLTGGV
TH_4603|M.thermoresistible__bu ATARATYLDAARR-RDQGRPYSQQASIAKLTATDAAMKVTTDAVQVFGGV
Mflv_1884|M.gilvum_PYR-GCK DVARVYTRHVVERQLAGDADLITEVCFAKNTAVEAGEWVANQAVQLFGGM
. . . : . : : **
Mb1706|M.bovis_AF2122/97 AFSKHLPIERAFRDARAGSVMAPTADALYDFYGRAVTGLPLF
Rv1679|M.tuberculosis_H37Rv AFSKHLPIERAFRDARAGSVMAPTADALYDFYGRAVTGLPLF
Mvan_5885|M.vanbaalenii_PYR-1 AFSKHLPIERNFRDARAGAVMAPTADVLYDFYGKAVTGLPLF
MMAR_2998|M.marinum_M GYASRTPTNRRYREAAFLPVQSPSEAQLRWELDRCR------
MUL_2239|M.ulcerans_Agy99 GYASRTPTNRRYREAAFLPVQSPSEAQLRWELDRCR------
MAV_2487|M.avium_104 GYASRTSASRRYREAAFIPVQSPSEAQLRWELAGCG------
MAB_2460|M.abscessus_ATCC_1997 GYALGTPANRRFREAAFLPIQSPSEGQLRWELKQYE------
MSMEG_4519|M.smegmatis_MC2_155 GYTLGSAANRRFREAAFLPVQSPSEGQLRWELTRYE------
TH_4603|M.thermoresistible__bu GYTRDYRVERYMREAKIMQIFEGTNQIQRLVIARGLTR----
Mflv_1884|M.gilvum_PYR-GCK GYMTESEVERQYRDMRILGIGGGTTEILTSLAAKTLGYQT--
.: .* *: : :