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M. thermoresistible (build 8) TH_4603 (-)

annotation: acyl-CoA dehydrogenase domain protein
coordinates: 347441 - 348580
length: 380

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_4603 - - 100% (380) acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8) TH_3846 - 3e-82 43.62% (376) PUTATIVE acyl-CoA dehydrogenase
M. thermoresistible (build 8) TH_2782 - 1e-74 40.81% (370) PUTATIVE acyl-CoA dehydrogenase domain protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3302c fadE25 5e-78 42.63% (373) acyl-CoA dehydrogenase FADE25
M. gilvum PYR-GCK Mflv_4943 - 0.0 82.59% (379) acyl-CoA dehydrogenase domain-containing protein
M. tuberculosis H37Rv Rv3274c fadE25 5e-78 42.63% (373) acyl-CoA dehydrogenase FADE25
M. leprae Br4923 MLBr_00737 fadE25 2e-78 43.16% (373) putative acyl-CoA dehydrogenase
M. abscessus ATCC 19977 MAB_3618c - 2e-78 43.13% (371) acyl-CoA dehydrogenase FadE
M. marinum M MMAR_1262 fadE25 8e-79 42.36% (373) acyl-CoA dehydrogenase FadE25
M. avium 104 MAV_2668 - 1e-175 79.84% (377) acyl-CoA dehydrogenase
M. smegmatis MC2 155 MSMEG_0108 - 0.0 87.80% (377) acyl-CoA dehydrogenase
M. ulcerans Agy99 MUL_2626 fadE25 2e-79 42.90% (373) acyl-CoA dehydrogenase FadE25
M. vanbaalenii PYR-1 Mvan_1476 - 1e-179 82.06% (379) acyl-CoA dehydrogenase domain-containing protein

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_1262|M.marinum_M               MAGWAGNPSFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQE
MUL_2626|M.ulcerans_Agy99           MAGWAGNPSFDLFQLPEEHQELRAAIRALAEKEIAPHAADVDENSRFPQE
Mb3302c|M.bovis_AF2122/97           MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEE
Rv3274c|M.tuberculosis_H37Rv        MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEE
MLBr_00737|M.leprae_Br4923          MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
MAB_3618c|M.abscessus_ATCC_199      ---MAGNPSFDLFKLGEEHDELRAAIRGLAEKEIAPHAKDVDEKARFPQE
TH_4603|M.thermoresistible__bu      -------MAVDRLLPSQEAAELIELTREIADKVLDPIVDRHEKDETYPEG
MSMEG_0108|M.smegmatis_MC2_155      -------MSVDRLLPSEEARDLIALTREVADKVLDPIVDEHERNETYPEG
Mflv_4943|M.gilvum_PYR-GCK          -------MPVDRLLPTDDARDLVELARQIADKVLDPIVDRHEKDETYPEG
Mvan_1476|M.vanbaalenii_PYR-1       -------MAVDRLLPTDEARELVDLARQIADKALDPIVDQHEKDETYPDG
MAV_2668|M.avium_104                -------MTVDRLLPTPEARELVRLAADVADKVLDPIVDEHEKNETYPEG
                                             .* :    :  ::      :*:* : * .   :.   :*: 

MMAR_1262|M.marinum_M               ALDALNASGFNAVHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
MUL_2626|M.ulcerans_Agy99           ALDALNASGFNALHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
Mb3302c|M.bovis_AF2122/97           ALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVN
Rv3274c|M.tuberculosis_H37Rv        ALVALNSSGFNAVHIPEEYGGQGADSVATCIVIEEVARVDASASLIPAVN
MLBr_00737|M.leprae_Br4923          ALAALNASGFNAIHVPEEYGGQGADSVAACIVIEEVARVDASASLIPAVN
MAB_3618c|M.abscessus_ATCC_199      ALDALVASGFNAVHVPEEYDGQGADSVAACIVIEEVARVCASSSLIPAVN
TH_4603|M.thermoresistible__bu      VFEQLGAAGLLSLPQPEEWGGGGQPYEVYLQVLEEIAARWASVAVAVSVH
MSMEG_0108|M.smegmatis_MC2_155      VFAQLGAAGLLSLPQPEQWGGGGQPYEVYLQVLEEIAARWAAVAVAVSVH
Mflv_4943|M.gilvum_PYR-GCK          VFATLGEAGLLSLPYPEEWGGGGQPYEVYLQVLEELAARWAAVAVAVSVH
Mvan_1476|M.vanbaalenii_PYR-1       VFATLGEAGLLSLPYPEEWGGGGQPYEVYLQVLEELAARWAAVAVAVSVH
MAV_2668|M.avium_104                VFATLGETGLLTLPHPEQWGGGGQPYEVYLQVLEELAARWAAVAVAVSVH
                                    .:  *  :*: ::  **::.* *    .   *:**:*   *: ::  :*:

MMAR_1262|M.marinum_M               KLGTMGLILRGSDDLKKQVLPSLADGAAMASYALSEREAGSDAGAMRTRA
MUL_2626|M.ulcerans_Agy99           KLGTMGLILRGSDELKKQVLPSLADGAAMASYALSEREAGSDAGAMRTRA
Mb3302c|M.bovis_AF2122/97           KLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRA
Rv3274c|M.tuberculosis_H37Rv        KLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRTRA
MLBr_00737|M.leprae_Br4923          KLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRTRA
MAB_3618c|M.abscessus_ATCC_199      KLGTMGLILNGSDELKKQVLPAIASGEAMASYALSEREAGSDAASMRTRA
TH_4603|M.thermoresistible__bu      SLSSHPLLVFGTEEQKKRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAA
MSMEG_0108|M.smegmatis_MC2_155      SLSSHPLLAFGTDEQKQRWLPGMLSGEQIGAYSLSEPQAGSDAAALRCAA
Mflv_4943|M.gilvum_PYR-GCK          SLSCHPLMSFGSDEQRQRWLPDMLGGSTIGAYSLSEPQAGSDAAALTCRA
Mvan_1476|M.vanbaalenii_PYR-1       SLSCHPLMSFGTDEQRQRWLPEMLGGSTIGAYSLSEPQAGSDAAALTCKA
MAV_2668|M.avium_104                VLSCHPLIAFGTDEQQQEWLPTMLGGHTIGAYSLSEPQAGSDAAALTCKA
                                     *.   *:  *::: ::. ** :     :.:*:*** :*****.::   *

MMAR_1262|M.marinum_M               KADGDDWILNGTKCWITNGGKSSWYTVMAVTDPEKGANGISAFMVHKDDE
MUL_2626|M.ulcerans_Agy99           KADGDDWILNGTKCWITNGGKSSWYTVMAVTDPENGANGISAFVVHKDDE
Mb3302c|M.bovis_AF2122/97           KADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKDDE
Rv3274c|M.tuberculosis_H37Rv        KADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKDDE
MLBr_00737|M.leprae_Br4923          KADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKDDE
MAB_3618c|M.abscessus_ATCC_199      KADGDDWIINGSKCWITNGGKSSWYTVMAVTDPEKKANGISAFMVHKDDE
TH_4603|M.thermoresistible__bu      TPTDGGYVINGSKSWITHGGKADFYTLFARTG--EGSRGVSCFLVPADQP
MSMEG_0108|M.smegmatis_MC2_155      RRDGDGFVLNGSKAWITHGGRADFYTLFARTG--EGSKGVSCFLVPGDLP
Mflv_4943|M.gilvum_PYR-GCK          TAVDGGYRITGSKAWITHGGIADFYNLFARTG--EGSQGISCFLVPRDTE
Mvan_1476|M.vanbaalenii_PYR-1       VAADGGYRINGAKAWITHGGIADFYNLFARTG--EGSQGISCFLVPRDTE
MAV_2668|M.avium_104                TATDGGYRVNGAKAWITHGGIADFYSLFARTG--EGGQGISCFLVDKDTE
                                       .. : :.* *.***:** : :*.::* *.  . ..*:*.*:*  *  

MMAR_1262|M.marinum_M               GFVVGPKERKLGIKGSPTTELYFENCRVPGDRMIGEPGTGFKTALATLDH
MUL_2626|M.ulcerans_Agy99           GFVVGPKERKLGIKGSPTTELYFENCRVPGDRMIGEPGTGFKTALATLDH
Mb3302c|M.bovis_AF2122/97           GFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDH
Rv3274c|M.tuberculosis_H37Rv        GFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATLDH
MLBr_00737|M.leprae_Br4923          GFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATLDH
MAB_3618c|M.abscessus_ATCC_199      GFTVGPLEHKLGIKGSPTAELYFENCRIPGDRIIGEPGTGFKTALQTLDH
TH_4603|M.thermoresistible__bu      GLSFGKPEEKMGLHAVPTTSAFYDNARIDADRRIGEEGQGLQIAFSALDS
MSMEG_0108|M.smegmatis_MC2_155      GLSFGKPEEKMGLHAVPTTSAFYDNARIDADRLIGTEGQGLSIAFSALDS
Mflv_4943|M.gilvum_PYR-GCK          GLTFGKPEEKMGLHAVPTTAAHYDDANLDSDRRIGTEGQGLQIAFSALDS
Mvan_1476|M.vanbaalenii_PYR-1       GLTFGKPEEKMGLHAVPTTAAHYENAFVEADRRIGAEGQGLQIAFSALDS
MAV_2668|M.avium_104                GLTFGKPEEKMGLHAIPTTTAHYDNALVSAQRRIGAEGQGLQIAFSALDS
                                    *: .*  *.*:*::. **:  .::.. : .:* **  * *:. *: :** 

MMAR_1262|M.marinum_M               TRPTIGAQAVGIAQGALDAAIAYTKDRKQFGKSISDFQAVQFMLADMAMK
MUL_2626|M.ulcerans_Agy99           TRPTIGAQAVGIAQGALDAAIAYTKDRKQFGKSISDFQAVQFMLADMAMK
Mb3302c|M.bovis_AF2122/97           TRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMK
Rv3274c|M.tuberculosis_H37Rv        TRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMAMK
MLBr_00737|M.leprae_Br4923          TRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMAMK
MAB_3618c|M.abscessus_ATCC_199      TRPTIGAQALGIAQGALDQAIAYTKDRKQFGKSISDFQGVQFMLADMAMK
TH_4603|M.thermoresistible__bu      GRLGIAAVATGLAQAALDEAVAYANERTAFGRKIIDHQGLGFLLADMAAA
MSMEG_0108|M.smegmatis_MC2_155      GRLGIAAVAVGIAQAALDEAVRYAHERTTFGRKIIDHQGLGFLLADMAAA
Mflv_4943|M.gilvum_PYR-GCK          GRLGIAAVAVGLAQAALDEAVAYSQERTTFGRKIIDHQGLAFLLADMAAA
Mvan_1476|M.vanbaalenii_PYR-1       GRLGIAAVAVGLAQAALDAAVDYSQERTTFGRKIIDHQGLAFLLADMAAA
MAV_2668|M.avium_104                GRLGIAAVAVGLAQAALDEAVSYAQQRTTFGRKIIDHQGLAFLLADMAAA
                                     *  *.* * *:**.*** *: *:::*. **..*  .*.: *:*****  

MMAR_1262|M.marinum_M               VESARLMVYSAAARAERGESNLGFISAASKCLASDVAMEVTTDAVQLFGG
MUL_2626|M.ulcerans_Agy99           VESARLMVYSAAARAERGESNLGFISAASKCLASDVAMEVTTDAVQLFGG
Mb3302c|M.bovis_AF2122/97           VEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLFGG
Rv3274c|M.tuberculosis_H37Rv        VEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLFGG
MLBr_00737|M.leprae_Br4923          VEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLFGG
MAB_3618c|M.abscessus_ATCC_199      VEAARLMVYTAAARAERGEKNLGFISSASKCFASDVAMEVTTDAVQLFGG
TH_4603|M.thermoresistible__bu      VATARATYLDAARRRDQGRP-YSQQASIAKLTATDAAMKVTTDAVQVFGG
MSMEG_0108|M.smegmatis_MC2_155      VVSARATYLDAARRRDAGLP-YSSQASVAKLVATDAAMKVTTDAVQVLGG
Mflv_4943|M.gilvum_PYR-GCK          VDSARATYLDAARRRDAGLP-YSRHASVAKLVATDAAMKVTTDAVQVLGG
Mvan_1476|M.vanbaalenii_PYR-1       VDAARATYLDAARRRDAGLP-YSRHASVAKLTATDAAMKVTTDAVQVFGG
MAV_2668|M.avium_104                VDSARATYLDAARRRDAGLP-YSRNASVAKLIATDAAMKVTTDAVQVFGG
                                    * :**     ** * : *    .  :: :*  *:* **:*******::**

MMAR_1262|M.marinum_M               AGYTVDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR-
MUL_2626|M.ulcerans_Agy99           AGYTVDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR-
Mb3302c|M.bovis_AF2122/97           AGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-
Rv3274c|M.tuberculosis_H37Rv        AGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-
MLBr_00737|M.leprae_Br4923          AGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-
MAB_3618c|M.abscessus_ATCC_199      AGYTTDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLTS
TH_4603|M.thermoresistible__bu      VGYTRDYRVERYMREAKIMQIFEGTNQIQRLVIARGLTR-
MSMEG_0108|M.smegmatis_MC2_155      VGYTRDFRVERYMREAKITQIFEGTNQIQRLVISRGLGT-
Mflv_4943|M.gilvum_PYR-GCK          AGYTRDYRVERYMREAKITQIFEGTNQIQRLVISRHLTRG
Mvan_1476|M.vanbaalenii_PYR-1       AGYTRDYRVERYMREAKITQIFEGTNQIQRLVISRHLARD
MAV_2668|M.avium_104                YGYTRDYRVERYMREAKITQIFEGTNQIQRLVIGRSLVGS
                                     *** *: *** **:*** **:********:*:.* *

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_4603	-	-	100% (380)	acyl-CoA dehydrogenase domain protein
M. thermoresistible (build 8)	TH_3846	-	3e-82	43.62% (376)	PUTATIVE acyl-CoA dehydrogenase
M. thermoresistible (build 8)	TH_2782	-	1e-74	40.81% (370)	PUTATIVE acyl-CoA dehydrogenase domain protein