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MAAHLQYTSEHHQFRELVRDFVQRTVVPNHEKWERDGQWDRSLFVEAGKLGLLGFSVPERLGGPGVDDFR YNAIVVDELQRAGAAAEAIAFSLQNDIVLPYLVELTTPEQQRRWLPGVVTGETVLGIAMTEPGTGSDLAG IRTTAVRDGDHYLVNGAKTFISNGQVGDLFVVAVRTAPDRHKGLSLLVVDADTPGFGRGRNLEKIGLHAQ DTSELSFTDMRVPAENLLEAEGRGFYQLMKNLPQERLSLAVGAVAAAEAVFAETLDYVKQRHAFGAPIAA FQNSQFVLAELATEIDVARTYLDDCLAAHLTGELTAARAARLKWWTTDLQVRTADRCLQLHGGYGYMREY GVARAFVDARIQTIYGGTNEIMKTIIAKDLGL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4768 | - | - | 100% (382) | long-chain specific acyl-CoA dehydrogenase |
| M. avium 104 | MAV_1883 | - | e-126 | 57.87% (375) | putative acyl-CoA dehydrogenase |
| M. avium 104 | MAV_2600 | - | e-125 | 57.49% (374) | acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2743c | fadE20 | 1e-118 | 56.50% (377) | acyl-CoA dehydrogenase FADE20 |
| M. gilvum PYR-GCK | Mflv_2118 | - | 1e-129 | 58.09% (377) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv2724c | fadE20 | 1e-119 | 56.76% (377) | acyl-CoA dehydrogenase FADE20 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 2e-45 | 29.22% (373) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3040c | - | 1e-115 | 54.93% (375) | acyl-CoA dehydrogenase |
| M. marinum M | MMAR_0697 | - | 0.0 | 83.51% (382) | acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_5197 | - | 1e-127 | 57.52% (379) | long-chain specific acyl-CoA dehydrogenase |
| M. thermoresistible (build 8) | TH_4527 | - | 1e-127 | 57.56% (377) | PUTATIVE acyl-CoA dehydrogenase domain protein |
| M. ulcerans Agy99 | MUL_3367 | fadE20 | 1e-116 | 55.97% (377) | acyl-CoA dehydrogenase FadE20 |
| M. vanbaalenii PYR-1 | Mvan_4587 | - | 1e-127 | 57.29% (377) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_4768|M.avium_104 --------MAAHLQYTSEHHQFRELVRDFVQRTVVPNHEKWERDGQWDRS
MMAR_0697|M.marinum_M --------MTSRPEYTPEHHQFRQLVRDFVHRIVVPAHEPGERRGQWDRA
Mflv_2118|M.gilvum_PYR-GCK ---------MKRTIYDAEHEAFRDTVKEYIERELVPNSEKWETERIVDRS
Mvan_4587|M.vanbaalenii_PYR-1 ---------MKRTIYDAEHEAFRETVKEYIERELVPNSEKWETERIVDRS
MSMEG_5197|M.smegmatis_MC2_155 ---------MKRLIYNEEHEAFRQTVKEYIERELVPHSEKWEAERIVDRS
TH_4527|M.thermoresistible__bu ---------MKRTVYEPEHEAFRETVREYIERELVPHAEKWETERIVDRS
Mb2743c|M.bovis_AF2122/97 ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAAYHDEWEKTKIVDRG
Rv2724c|M.tuberculosis_H37Rv ---MGSATKYQRTLFEPEHELFRESYRAFLDRHVAPYHDEWEKTKIVDRG
MUL_3367|M.ulcerans_Agy99 ---MGSAIKYQRTLFEPEHDLFRESYRGFLERHVALYHDEWEKAKIVDRG
MAB_3040c|M.abscessus_ATCC_199 ---MAGAVKFKRTIFEPEHELFRESFKTFLDRHAEPYKEEWEKNKIVDRA
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
**. :* : .: : .
MAV_4768|M.avium_104 LFVEAGKLGLLGFSVPERLGGPGVDDFRYNAIVVDELQRAGAAAEAIAFS
MMAR_0697|M.marinum_M LFTEAARLGLLGFSVPERFGGPGVNDFRYNAIVIDELQRAGAASEAIAFT
Mflv_2118|M.gilvum_PYR-GCK AYTAAGKYGLIGFNMPEEFGGGGTDDFRFNAIIDEEIAKAGVH--GPALS
Mvan_4587|M.vanbaalenii_PYR-1 AYTAAGKYGLIGFNMPEEYGGGGSEDFRFNAIIDEEMAKSGVH--GPALS
MSMEG_5197|M.smegmatis_MC2_155 AYTAAGKYGLIGFNMPEEFGGGGSDDFRFNAIIDEEIAKSGVH--GPALS
TH_4527|M.thermoresistible__bu AYVAAGKYGLIGFNMPEKYGGGGTDDFRFNAVIDEEMAKAGVP--GPALS
Mb2743c|M.bovis_AF2122/97 VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYS--GIGFG
Rv2724c|M.tuberculosis_H37Rv VWLEAGKQGFLGMAVPEEYGGGGNADFRYNTVITEETCAGRYS--GIGFG
MUL_3367|M.ulcerans_Agy99 VWLEAGKQGFLGMAVPEEYGGGGNPDFRYNTIITEETSAGRYS--GIGFG
MAB_3040c|M.abscessus_ATCC_199 LWVEAGKQGFLGTDMPEEFGGGGLIDFRYNTIITEEVTKGRHT--GVGFS
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQG-ADSVAACIVIEEVARVDAS--ASLIP
*: . :**. ** * * :: :* . :
MAV_4768|M.avium_104 LQNDIVLPYLVELTTPEQQRRWLPGVVTGETVLGIAMTEPGTGSDLAGIR
MMAR_0697|M.marinum_M LQNDVVLPYLTDLTTLEQQQRWLPGVVTGDTVLGIAMTEPGAGSDLAGIH
Mflv_2118|M.gilvum_PYR-GCK LHNDVVGPYFKDLTNDEQKKRWLPGVTSGETIIAVAMTEPGAGSDLAGIR
Mvan_4587|M.vanbaalenii_PYR-1 LHNDVVGPYFKDLTNDEQKKRWLPGIASGETIIAVAMTEPGAGSDLAGIR
MSMEG_5197|M.smegmatis_MC2_155 LHNDVVGPYFKELANDEQRRRWLPGITSGELIIAIAMTEPGAGSDLAGIR
TH_4527|M.thermoresistible__bu LHNDVVAPYFNNLCTEEQKERWMPGIASGETIIAIAMTEPGAGSDLAGIR
Mb2743c|M.bovis_AF2122/97 LHNDIVAPYLLALATEEQKRRWFPNFCTGELTTAIAMTEPGTGSDLQGIT
Rv2724c|M.tuberculosis_H37Rv LHNDIVAPYLLALATEEQKRRWFPNFCTGELITAIAMTEPGTGSDLQGIT
MUL_3367|M.ulcerans_Agy99 LHNEIVAPYLLALATEEQKQRRLPKFCTGEFITAIAMTEPGTGSDLQGIK
MAB_3040c|M.abscessus_ATCC_199 LHNDVAGPYFRDLANDEQKARWFPGFCSGELISAIAMTEPGTGSDLQGIK
MLBr_00737|M.leprae_Br4923 AVNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMR
*.: : . * : : :* . : . *::* :*** .:
MAV_4768|M.avium_104 TTAVRDGDHYLVNGAKTFISNGQVGDLFVVAVRTAPDR-HKGLSLLVVDA
MMAR_0697|M.marinum_M TTAVRDGSHYVVNGAKTFISNGQSGDLFVIAVRTSPER-HQGLSLLVVDA
Mflv_2118|M.gilvum_PYR-GCK TSAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVER
Mvan_4587|M.vanbaalenii_PYR-1 TSAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVER
MSMEG_5197|M.smegmatis_MC2_155 TSAVRDGDDWIINGSKTFISSGINCDLCVVVARTDPEAGHKGFSLFVVER
TH_4527|M.thermoresistible__bu TSAVRDGDDWIINGSKTFISSGINCDLVVVVCRTDPEAGHKGFTLFVVER
Mb2743c|M.bovis_AF2122/97 TRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVER
Rv2724c|M.tuberculosis_H37Rv TRAVKHGDHYVLNGSKTFITNGINSDLVIVVAQTDPEKGAQGFSLLVVER
MUL_3367|M.ulcerans_Agy99 TRAVKQGDHYLLNGSKTFITNGINADLVIVVAQTDPEKGAQGFSLLVVER
MAB_3040c|M.abscessus_ATCC_199 TRAVKDGDHYILNGAKTFITNGINADLVIVVAQTDPEKGALGFSLIVVER
MLBr_00737|M.leprae_Br4923 TRAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHK
* * .*..:::** * :*:.* : * *: *:: ::*.
MAV_4768|M.avium_104 DTPGFGRGRNLEKIGLHAQDTSELSFTDMRVPAENLLEAEGRGFYQLMKN
MMAR_0697|M.marinum_M TTPGFHRGRSLEKIGLHAQDTSELSFTDMRVPVENLLQNEGMGFYQLMRN
Mflv_2118|M.gilvum_PYR-GCK DMEGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTN
Mvan_4587|M.vanbaalenii_PYR-1 GMEGFTRGRKLDKMGLHSQDTSELHFENVRVPNANLLGKEGRGFYHLMTN
MSMEG_5197|M.smegmatis_MC2_155 GMEGFTRGRKLDKMGLHSQDTSELHFENVRVPHANLLGKEGRGFYHLMTN
TH_4527|M.thermoresistible__bu GMEGFTRGRKLDKMGLHAQDTAELHFENVRVPHANLLGKEGHGFYHLMQN
Mb2743c|M.bovis_AF2122/97 GMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQN
Rv2724c|M.tuberculosis_H37Rv GMAGFERGRQLDKIGLDAQDTAELSFTDVAVPAENLLGQEGMGFIYLMQN
MUL_3367|M.ulcerans_Agy99 GMEGFERGRHLDKIGLDAQDTAELSFSDVQVPVENLLGQEGMGFIYLMQN
MAB_3040c|M.abscessus_ATCC_199 GMEGFERGRKLDKVGLDAQDTAELSFTDVRVPAANLLGEEGQGFIYLMKN
MLBr_00737|M.leprae_Br4923 DDEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALAT
** * .*:*:... *:** * . :* .:: * ** : .
MAV_4768|M.avium_104 LPQERLSLAVGAVAAAEAVFAETLDYVKQRHAFGAPIAAFQNSQFVLAEL
MMAR_0697|M.marinum_M LPQERLALAVGAVAAAEGILAETLDYVRQRKAFGSPIASFQHSQFLLAEL
Mflv_2118|M.gilvum_PYR-GCK LPSERLSIAISAIAGARAVFDETLQYSKDRKAFGQSIGSFQHNRFLLAEM
Mvan_4587|M.vanbaalenii_PYR-1 LPSERLSIAISAIAGARAVFQETLQYAKDRKAFGQPIGSFQHNRFLLAEM
MSMEG_5197|M.smegmatis_MC2_155 LPSERLSIAISAIAGARAVFDETLQYCKDRKAFGQPIGSFQHNRFLLAEM
TH_4527|M.thermoresistible__bu LPSERLSIAISAIAGARATWRETLQYAKDRKAFGKPIGSFQHNRFLLAEM
Mb2743c|M.bovis_AF2122/97 LPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAEL
Rv2724c|M.tuberculosis_H37Rv LPQERISIAIMAAAGMESVLEQTLQYAKERKAFGRSIGSFQNSRFLLAEL
MUL_3367|M.ulcerans_Agy99 LPQERISIAIMAAAGMESVLDQTLQYTKERKAFGRSIGNFQNSRFVLAEL
MAB_3040c|M.abscessus_ATCC_199 LPQERMSIAVMAAAAMESVLEETIAYTTERKAFGKPIKSFQNSRFLLAEL
MLBr_00737|M.leprae_Br4923 LDHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADM
* * ::. * . .. :: * :*: ** .* ** :*:**::
MAV_4768|M.avium_104 ATEIDVARTYLDDCLAAHLTGE-LTAARAARLKWWTTDLQVRTADRCLQL
MMAR_0697|M.marinum_M ATEIDIARTYLDDCLAQHLAGE-LTAARAARLKWWTTELQVRTADRCLQL
Mflv_2118|M.gilvum_PYR-GCK ETELEVTETYIDRCLQGVVDGE-LTAVEAAKAKWWATEVAKKVVDQCVQL
Mvan_4587|M.vanbaalenii_PYR-1 ETELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKVVDQCVQL
MSMEG_5197|M.smegmatis_MC2_155 ETELEVTENYIDRCLQGVVDGE-LTAVEAAKAKWWATETAKKIVDNCVQL
TH_4527|M.thermoresistible__bu DTELEVSEQYIDRCLQAVVDGE-LTAVEAAKAKWWCTEVAKKVVDQCVQL
Mb2743c|M.bovis_AF2122/97 ATEATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQL
Rv2724c|M.tuberculosis_H37Rv ATEATVVRIMVDEFIKLHLAGK-LTAEQAAMAKWYATEKQVYLNDRCLQL
MUL_3367|M.ulcerans_Agy99 ATEATMVRIMVDESIELHLDGK-LTAEQAAMAKWYSTEKQVSLNDRCLQL
MAB_3040c|M.abscessus_ATCC_199 ATDATVIRVMVDEFISLLNKEE-LSVEQAAMAKWYSTEKQVHLIDRCLQL
MLBr_00737|M.leprae_Br4923 AMKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQL
. . : : :* * : :: .:**
MAV_4768|M.avium_104 HGGYGYMREYGVARAFVDARIQTIYGGTNEIMKTIIAKDLGL
MMAR_0697|M.marinum_M HGGYGYMREYRVSQAFVDARIQTIYGGTNEIMKTIIAKDLGI
Mflv_2118|M.gilvum_PYR-GCK HGGYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV
Mvan_4587|M.vanbaalenii_PYR-1 HGGYGYMLEYRVARAYVDGRIQTIFGGTTEIMKEIIGRELGV
MSMEG_5197|M.smegmatis_MC2_155 HGGYGYMMEYRVARAYVDGRIQTIFGGTTEIMKEIIGRDLGV
TH_4527|M.thermoresistible__bu HGGYGYMMEYRVARDFVDGRIQTIFGGTTEIMKEIIGRDLGL
Mb2743c|M.bovis_AF2122/97 HGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
Rv2724c|M.tuberculosis_H37Rv HGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRGLGV
MUL_3367|M.ulcerans_Agy99 HGGYGYMREYPVARAYLDSRVQTIYGGTTEIMKEIIGRSLGI
MAB_3040c|M.abscessus_ATCC_199 HGGYGFMREYPVARAYMDSRIQTIYGGTTEIMKEIIGRSL--
MLBr_00737|M.leprae_Br4923 FGGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR
.** *: :: * : *.:: *: **.:* : ::.: *