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MTAMLADSALDRVARTVAARAAELDEQRTDVRTDLAELGREGLLDLDLPGMVRVIDEVSAHSLAVGFSTW AHHMSLRYLNASSTGGFDEQISALAAARKIGVTAMAAGLKQIAGLGQVPVTGDNDGSDLIVSGPIRWATN VFPDALMVLPVRVGEHTVVVAVGTGDDGVTVDPAPPLTALGATASTSLHLNEVRVAADQVLATDLAAFVA RIRPAFLLLQTAFCVGITRAALTAATEAHTGPLARFGAELDDAATRAADIRARLYGWASDPGTATVPDLI RLRLDAAHAAVDVTRLELSLTGGVGYTLGSAANRRFREAAFLPVQSPSEGQLRWELTRYE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4519 | - | - | 100% (340) | NrtC protein |
| M. smegmatis MC2 155 | MSMEG_0108 | - | 5e-09 | 25.42% (358) | acyl-CoA dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3982 | - | 5e-06 | 22.03% (345) | acyl-CoA dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3302c | fadE25 | 1e-06 | 22.71% (339) | acyl-CoA dehydrogenase FADE25 |
| M. gilvum PYR-GCK | Mflv_4943 | - | 3e-06 | 25.93% (324) | acyl-CoA dehydrogenase domain-containing protein |
| M. tuberculosis H37Rv | Rv3274c | fadE25 | 1e-06 | 22.71% (339) | acyl-CoA dehydrogenase FADE25 |
| M. leprae Br4923 | MLBr_00737 | fadE25 | 9e-06 | 21.83% (339) | putative acyl-CoA dehydrogenase |
| M. abscessus ATCC 19977 | MAB_2460 | - | 1e-95 | 55.00% (340) | hypothetical protein MAB_2460 |
| M. marinum M | MMAR_2998 | - | 1e-54 | 38.62% (334) | hypothetical protein MMAR_2998 |
| M. avium 104 | MAV_2487 | - | 6e-55 | 37.97% (345) | NtrC protein |
| M. thermoresistible (build 8) | TH_3846 | - | 5e-06 | 21.47% (340) | PUTATIVE acyl-CoA dehydrogenase |
| M. ulcerans Agy99 | MUL_2239 | - | 2e-50 | 36.76% (340) | hypothetical protein MUL_2239 |
| M. vanbaalenii PYR-1 | Mvan_1476 | - | 3e-07 | 26.18% (359) | acyl-CoA dehydrogenase domain-containing protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3302c|M.bovis_AF2122/97 MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEE
Rv3274c|M.tuberculosis_H37Rv MVGWAGNPSFDLFKLPEEHDEMRSAIRALAEKEIAPHAAEVDEKARFPEE
MLBr_00737|M.leprae_Br4923 MVGWSGNPLFDLFKLPEEHNELRATIRALAEKEIAPHAADVDQRARFPEE
TH_3846|M.thermoresistible__bu MAAWSGNPSFELFQLPEEHIALREAIRALAEKEIAPYAAEVDEKARFPEE
Mflv_4943|M.gilvum_PYR-GCK -------MPVDRLLPTDDARDLVELARQIADKVLDPIVDRHEKDETYPEG
Mvan_1476|M.vanbaalenii_PYR-1 -------MAVDRLLPTDEARELVDLARQIADKALDPIVDQHEKDETYPDG
MSMEG_4519|M.smegmatis_MC2_155 -------------MTAMLADSALDR----VARTVAARAAELDEQRTDVRT
MAB_2460|M.abscessus_ATCC_1997 --------------MAREIDDELER----VVDEVARRAAALDADQTDVRV
MMAR_2998|M.marinum_M --------------MTATVDAATDLLHSELLAEIRAHASALDRGDGTARR
MUL_2239|M.ulcerans_Agy99 --------------MTATVDAATDLLHSELLAEIRAHASALDRGDGTARR
MAV_2487|M.avium_104 --------------MTATVDGATGLLDAALVEDIRAHAAVLDRGQDSARR
. : . :
Mb3302c|M.bovis_AF2122/97 ALVALNSSGFNAVHIPEEYGGQGADSVATCIV--IEEVARVDASASLIPA
Rv3274c|M.tuberculosis_H37Rv ALVALNSSGFNAVHIPEEYGGQGADSVATCIV--IEEVARVDASASLIPA
MLBr_00737|M.leprae_Br4923 ALAALNASGFNAIHVPEEYGGQGADSVAACIV--IEEVARVDASASLIPA
TH_3846|M.thermoresistible__bu ALAALNSSGFSAIHVPEEYGGQGADSVATCIV--IEEVARVDCSASLIPA
Mflv_4943|M.gilvum_PYR-GCK VFATLGEAGLLSLPYPEEWGGGGQPYEVYLQV--LEELAARWAAVAVAVS
Mvan_1476|M.vanbaalenii_PYR-1 VFATLGEAGLLSLPYPEEWGGGGQPYEVYLQV--LEELAARWAAVAVAVS
MSMEG_4519|M.smegmatis_MC2_155 DLAELGREGLLDL--------DLPGMVRVID-----EVSAHSLAVGFSTW
MAB_2460|M.abscessus_ATCC_1997 DIAALGAQGLFHAGGVGT---DLAPMVRTIE-----RVATGSLAVGFSAW
MMAR_2998|M.marinum_M SFPGLGAVGLLGLGAPGNSDGCLPQMAEVIS-----VISGECMSTGFSVW
MUL_2239|M.ulcerans_Agy99 SFPGLGAVGLLGLGAPGNSDGCLPQMAEAISVISISVISGECMSTGFSVW
MAV_2487|M.avium_104 SFTALGEAGVLGIGAPGNRDGRLPVMAEVIR-----SISGICMSTGFSLW
: *. *. :: :...
Mb3302c|M.bovis_AF2122/97 VNKLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRT
Rv3274c|M.tuberculosis_H37Rv VNKLGTMGLILRGSEELKKQVLPALAAEGAMASYALSEREAGSDAASMRT
MLBr_00737|M.leprae_Br4923 VNKLGTMGLILRGSEELKKQVLPSLAAEGAMASYALSEREAGSDAASMRT
TH_3846|M.thermoresistible__bu VNKLGTMGLILRGSEELKKQVLPAVASGEAMASYALSEREAGSDAASMRT
Mflv_4943|M.gilvum_PYR-GCK VHSLSCHPLMSFGSDEQRQRWLPDMLGGSTIGAYSLSEPQAGSDAAALTC
Mvan_1476|M.vanbaalenii_PYR-1 VHSLSCHPLMSFGTDEQRQRWLPEMLGGSTIGAYSLSEPQAGSDAAALTC
MSMEG_4519|M.smegmatis_MC2_155 AHHMSLRYLNASSTGGFDEQISALAAARKIGVTAMAAGLKQIAGLGQVPV
MAB_2460|M.abscessus_ATCC_1997 AHRMAIEYVSLAAADFRAEHLAELTGGHRPGVTAMAAGLKQAAGLGEVPL
MMAR_2998|M.marinum_M ASRMAVEYLLTAATEYSLAVVGPLLAGAALGISGMAAAFKEAAGCGDLEL
MUL_2239|M.ulcerans_Agy99 ASRMAVEYLLTAATEYSLAVVGPLLAGAALGISGMAAAFKEAAGCADLEL
MAV_2487|M.avium_104 AHRMTVEYLLTAATPFSAVAVRPLLRGSVLGVTGMAAAFKEAAGCGSMEL
. : : .: . : : : :. . :
Mb3302c|M.bovis_AF2122/97 RAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKD
Rv3274c|M.tuberculosis_H37Rv RAKADGDHWILNGAKCWITNGGKSTWYTVMAVTDPDRGANGISAFMVHKD
MLBr_00737|M.leprae_Br4923 RAKADGDDWILNGFKCWITNGGKSTWYTVMAVTDPDKGANGISAFIVHKD
TH_3846|M.thermoresistible__bu RAVADGDDWILNGSKCWITNGGKSTWYTVMAVTDPDKGANGISAFMVHKD
Mflv_4943|M.gilvum_PYR-GCK RATAVDGGYRITGSKAWITHGGIADFYNLFARTG--EGSQGISCFLVPRD
Mvan_1476|M.vanbaalenii_PYR-1 KAVAADGGYRINGAKAWITHGGIADFYNLFARTG--EGSQGISCFLVPRD
MSMEG_4519|M.smegmatis_MC2_155 TGDNDGSDLIVSGPIRWATN----VFPDALMVLPVR-VGEHTVVVAVGTG
MAB_2460|M.abscessus_ATCC_1997 RATNQGDGLSISGPIRWASN----VFPDALMVVPACGADGTTYVVAIEVC
MMAR_2998|M.marinum_M TARPVTGGYQLSGSIRWASN----LYQDSVLVTAARTERGEKLIVALPLA
MUL_2239|M.ulcerans_Agy99 TARPVTGGYQLSGSIRWASN----LYQDSVLVTAARTERGEELIVALPLA
MAV_2487|M.avium_104 TATPVAGGYRVSGPIRWASN----LYPDSTMVTAVRTEAGERLIVAVPLD
. . :.* * :: : . :
Mb3302c|M.bovis_AF2122/97 DEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATL
Rv3274c|M.tuberculosis_H37Rv DEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATL
MLBr_00737|M.leprae_Br4923 DEGFSIGPKEKKLGIKGSPTTELYFDKCRIPGDRIIGEPGTGFKTALATL
TH_3846|M.thermoresistible__bu DEGFTVGPKERKLGIKGSPTTELYFENCRIPGDRIIGEPGTGFKTALATL
Mflv_4943|M.gilvum_PYR-GCK TEGLTFGKPEEKMGLHAVPTTAAHYDDANLDSDRRIGTEGQGLQIAFSAL
Mvan_1476|M.vanbaalenii_PYR-1 TEGLTFGKPEEKMGLHAVPTTAAHYENAFVEADRRIGAEGQGLQIAFSAL
MSMEG_4519|M.smegmatis_MC2_155 DDGVTVDPAPPLTALGATASTSLHLNEVRVAADQVLATDLAAFVARIR--
MAB_2460|M.abscessus_ATCC_1997 ANGVRIQRPPDLMALTATASTSLHLDDVRVPMEHVISTDLQGFVRRIR--
MMAR_2998|M.marinum_M TPGVAVGDHFELLAMGSTASSQLELQDVYVASEQVLSTDCGGFLDAVR--
MUL_2239|M.ulcerans_Agy99 TPGVAVGDHFELLAMASTASSQLELQDVYVASEQVLSTDCGGFLDAVR--
MAV_2487|M.avium_104 TPGVILGEHFDLLALGSTASSYLNFDGAHIADEQVLSRDFDGFLQAVR--
*. . .: . .:: : : :: :. .: .
Mb3302c|M.bovis_AF2122/97 DHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMA
Rv3274c|M.tuberculosis_H37Rv DHTRPTIGAQAVGIAQGALDAAIAYTKDRKQFGESISTFQAVQFMLADMA
MLBr_00737|M.leprae_Br4923 DHTRPTIGAQAVGIAQGALDAAIVYTKDRKQFGESISTFQSIQFMLADMA
TH_3846|M.thermoresistible__bu DHTRPTIGAQAVGIAQGALDAAIAYTKERKQFGRPVSDNQGVQFMLADMA
Mflv_4943|M.gilvum_PYR-GCK DSGRLGIAAVAVGLAQAALDEAVAYSQERTTFGRKIIDHQGLAFLLADMA
Mvan_1476|M.vanbaalenii_PYR-1 DSGRLGIAAVAVGLAQAALDAAVDYSQERTTFGRKIIDHQGLAFLLADMA
MSMEG_4519|M.smegmatis_MC2_155 PAFLLLQTAFCVGITRAALTAATEAHTG---------PLARFGAELDDAA
MAB_2460|M.abscessus_ATCC_1997 PAFLLLQTAFCSGVSVAALEGARAAHGI---------IAAQFSTELDDIT
MMAR_2998|M.marinum_M PTFLVLQSAMCIGLARTALAQSRIALAG---------VNSVYVPDLDLIA
MUL_2239|M.ulcerans_Agy99 PTFLVLQSGMCIGLARTALAQSRIALAG---------VNSVYAPDFDLIA
MAV_2487|M.avium_104 PTFLVLQSAMCLGLSRTAVRQAGFGLGG---------VNAVFRADVEAIT
. . *:: *: : . :
Mb3302c|M.bovis_AF2122/97 MKVEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLF
Rv3274c|M.tuberculosis_H37Rv MKVEAARLMVYSAAARAERGEPDLGFISAASKCFASDVAMEVTTDAVQLF
MLBr_00737|M.leprae_Br4923 MKVEAARLIVYAAAARAERGEPDLGFISAASKCFASDIAMEVTTDAVQLF
TH_3846|M.thermoresistible__bu MKIEAARLMVYSAAARAERGEGDLGFISAASKCFASDVAMEVTTDAVQLF
Mflv_4943|M.gilvum_PYR-GCK AAVDSARATYLDAARRRDAGLP-YSRHASVAKLVATDAAMKVTTDAVQVL
Mvan_1476|M.vanbaalenii_PYR-1 AAVDAARATYLDAARRRDAGLP-YSRHASVAKLTATDAAMKVTTDAVQVF
MSMEG_4519|M.smegmatis_MC2_155 TRAADIRARLYGWASDPGTATVP---DLIRLRLDAAHAAVDVTRLELSLT
MAB_2460|M.abscessus_ATCC_1997 RRSHALRERLYTFAAVPSAPDIA---DLLRLRLDAAGLAGAASRLEVTLS
MMAR_2998|M.marinum_M ERLALAESTLSGAAASVGTQRPAGRRELLSLRLSSAKIACASADLEIRVA
MUL_2239|M.ulcerans_Agy99 ERLALAESTLSGAAASVGTQRPAGRRELLSLRLSSAKIACASADREIRVA
MAV_2487|M.avium_104 EKLGAAEETLAKLAAAVGGPAAPSKKELLSLRLAAAELAAASADVEIRTA
. * : :: * : :
Mb3302c|M.bovis_AF2122/97 GGAGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-
Rv3274c|M.tuberculosis_H37Rv GGAGYTTDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-
MLBr_00737|M.leprae_Br4923 GGAGYTSDFPVERFMRDAKITQIYEGTNQIQRVVMSRALLR-
TH_3846|M.thermoresistible__bu GGYGYTQDFPVERMMRDAKITQIYEGTNQIQRVVMSRALLR-
Mflv_4943|M.gilvum_PYR-GCK GGAGYTRDYRVERYMREAKITQIFEGTNQIQRLVISRHLTRG
Mvan_1476|M.vanbaalenii_PYR-1 GGAGYTRDYRVERYMREAKITQIFEGTNQIQRLVISRHLARD
MSMEG_4519|M.smegmatis_MC2_155 GGVGYTLGSAANRRFREAAFLPVQSPSEGQLRWELTRYE---
MAB_2460|M.abscessus_ATCC_1997 GGAGYALGTPANRRFREAAFLPIQSPSEGQLRWELKQYE---
MMAR_2998|M.marinum_M GGKGYASRTPTNRRYREAAFLPVQSPSEAQLRWELDRCR---
MUL_2239|M.ulcerans_Agy99 GGKGYASRTPTNRRYREAAFLPVQSPSEAQLRWELDRCR---
MAV_2487|M.avium_104 GGKGYASRTSASRRYREAAFIPVQSPSEAQLRWELAGCG---
** **: ..* *:* : : . :: * :