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M. tuberculosis H37Rv Rv3328c (sigJ)

annotation: RNA polymerase sigma factor SigJ
coordinates: 3713394 - 3714332
length: 312

EVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLRWDSPDTVIADPRAWLTTVVSRLGLDKLRSAAHRR
ETYTGTWLPEPVVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPFAEVAEVLGTS
EAAARQLASRARKAVTAQPALISGDPDPAHNEVVGRLMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTA
VRAVRGSDKVVRFILGLVQRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDGKVCA
LWDIANPDKFTGSPLKERRAQPTGRGRHHRN*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. tuberculosis H37RvRv3328csigJ-100% (312)RNA polymerase sigma factor SigJ
M. tuberculosis H37RvRv1189sigI3e-2935.91% (220) RNA polymerase sigma factor SigI
M. tuberculosis H37RvRv0182csigG1e-1930.98% (255) RNA polymerase factor sigma-70

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3361csigJ1e-17799.68% (312) RNA polymerase sigma factor SigJ
M. gilvum PYR-GCKMflv_4852-1e-11068.92% (296) RNA polymerase sigma factor SigJ
M. leprae Br4923MLBr_01076sigE1e-0629.81% (161) RNA polymerase sigma factor SigE
M. abscessus ATCC 19977MAB_3678c-1e-10865.65% (294) RNA polymerase sigma factor SigJ
M. marinum MMMAR_1196sigJ1e-12777.67% (300) alternative RNA polymerase sigma factor SigJ
M. avium 104MAV_4301-1e-13480.20% (298) RNA polymerase sigma factor SigJ
M. smegmatis MC2 155MSMEG_1666-1e-11770.21% (292) RNA polymerase sigma factor SigJ
M. thermoresistible (build 8)TH_1142-4e-4536.01% (286) RNA polymerase sigma factor, sigma-70 family protein
M. ulcerans Agy99MUL_3630-1e-3939.00% (300) alternative RNA polymerase sigma factor SigJ- like
M. vanbaalenii PYR-1Mvan_1575-1e-11369.70% (297) RNA polymerase sigma factor SigJ

CLUSTAL 2.0.9 multiple sequence alignment


Rv3328c|M.tuberculosis_H37Rv        --------------------MEVSEFEALRQHLMSVAYRLTGTVADAEDI
Mb3361c|M.bovis_AF2122/97           --------------------MEVSEFEALRQHLMSVAYRLTGTVADAEDI
MAV_4301|M.avium_104                MSLVSLTPGPMAYARFMTSAQQVSEFESLRPHLMSVAYRLTGTVADAEDI
MMAR_1196|M.marinum_M               --------------MAVLGAQAASTFESLRPHLMSVAYRLTGTVADAEDI
Mflv_4852|M.gilvum_PYR-GCK          ------MPHGGIYTRRMTASARVAEFEQMRPHLLSVAYRLTGTVADAEDI
Mvan_1575|M.vanbaalenii_PYR-1       ----------------MTTSARVGEFEQLRPHLLSVAYRLTGTLADAEDI
MSMEG_1666|M.smegmatis_MC2_155      ----------------MTTAARTDQFEALRPHLLAVAYRLTGTYADAEDI
MAB_3678c|M.abscessus_ATCC_199      --------------MVVRAGDRTDEFEALRPRLQAVAYRLTGSVADAEDI
MUL_3630|M.ulcerans_Agy99           ----------------MTDPALLARFQAARPRLGALAYRMLGSLADAEDV
TH_1142|M.thermoresistible__bu      --------MTGSGAPSARGDEHAERFTHLRPLLFTIAYEILGSATEADDV
MLBr_01076|M.leprae_Br4923          ---------MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDL
                                                                    :        .  :..:*:

Rv3328c|M.tuberculosis_H37Rv        VQEAWLRWDSPDT------VIADPRAWLTTVVSRLGLDKLRSAAHRRETY
Mb3361c|M.bovis_AF2122/97           VQEAWLRWDSQDT------VIADPRAWLTTVVSRLGLDKLRSAAHRRETY
MAV_4301|M.avium_104                VQDAWLRWHGQDG------AITDLRAWLTTVVSRLGLDRLRSATHRRETY
MMAR_1196|M.marinum_M               VQEAWLRWDAAPGR----DDVADLRAWLTTVVSRLGLDKLRSAARRRETY
Mflv_4852|M.gilvum_PYR-GCK          VQDAWLRWSTHRG-----AAVEDLKAWLTTVVSRLALDKLRSAAHRRETY
Mvan_1575|M.vanbaalenii_PYR-1       VQDAWLRWEANSA-----TVIEDLKAWLTTVVSRLALDRLRSAAHRRETY
MSMEG_1666|M.smegmatis_MC2_155      VQEAWIRWAGQEA------PIENLQAWLTTVVSRLGLDRLRSAAHRRESY
MAB_3678c|M.abscessus_ATCC_199      VQDAWLRLYSTTA------EIEDLAAWLTTVVSRLGLDRLRSAVYRRETY
MUL_3630|M.ulcerans_Agy99           VQEAWLRLNATTDRPEGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREE
TH_1142|M.thermoresistible__bu      LQESYLRWAEVDLA-----AVRDTKSYLAKLVSRQALNALRAGARRREDY
MLBr_01076|M.leprae_Br4923          IITNLLSPTIMSHP-----PPSRDDDWVEPFDALQGTAVFDATGDKATMP
                                    :    :                    ::  . :      :     :    

Rv3328c|M.tuberculosis_H37Rv        TGTWLPEPVVTGLD---ATDPLAAVVAAEDARFAAMVVLERLRPDQRVAF
Mb3361c|M.bovis_AF2122/97           TGTWLPEPVVTGLD---ATDPLAAVVAAEDARFAAMVVLERLRPDQRVAF
MAV_4301|M.avium_104                TGNWLPEPVVTGLGPHSGADPLAAVVAGEDARFAAMVVLERLSPDQRVAF
MMAR_1196|M.marinum_M               TGHWLPEPVVTGLGDAGGADPLSAVVAAEDARFAVMVVLERLSPDQRVAF
Mflv_4852|M.gilvum_PYR-GCK          VGEWLPEPVVTGLD---GRDPLSALVADEDARFAAMVVLENLTPDQRVAF
Mvan_1575|M.vanbaalenii_PYR-1       VGEWLPEPVVTGFD---GVDPLASVVAGEDARFAAMVVLENLTPDQRVAF
MSMEG_1666|M.smegmatis_MC2_155      YGEWLPEPVVTGID---GNDPLNAVVAGEDARFAAMVVLEQLSPDQRVAF
MAB_3678c|M.abscessus_ATCC_199      VGEWLPEPVVTGLD---GDDPLAALVASEDARFAAMVVLDRLAPDQRVAF
MUL_3630|M.ulcerans_Agy99           LVGQLPDPIVDGVA---AFDPEHHAMLADAVGLALFVVLDTLAPAERLAF
TH_1142|M.thermoresistible__bu      VGPWLPEPLLLEER-----DASADVVLAESVSMAMMVVLESLTPDERAVF
MLBr_01076|M.leprae_Br4923          SWEELVRQHAARVY------WLAYRLSGNQHDAEDLTQETFIRVFRSVQN
                                        *                    :  :      :.    :   .    

Rv3328c|M.tuberculosis_H37Rv        VLHDGFAVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALISGDPDPAH
Mb3361c|M.bovis_AF2122/97           VLHDGFAVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALISGDPDPAH
MAV_4301|M.avium_104                VLHDGFAVPFSEVAEVLGTSEAAARQLASRARKVVSAQP---PPEPDPSH
MMAR_1196|M.marinum_M               VLHDGFAMPFAEVAGVIGASEAAARQLASRARKAVAAAP---PPQPDPTH
Mflv_4852|M.gilvum_PYR-GCK          VLHDGFAVPFSAIAEVLGTSTQAARQLASRARRAVSSAP-----PPAADH
Mvan_1575|M.vanbaalenii_PYR-1       VLHDGFAVPFAEIAEVLGSSPESARQLASRARRAASAAP-----PPADEH
MSMEG_1666|M.smegmatis_MC2_155      VLYDGFGVPFPDIADVLGVSAASARQLASRARRAVADAP---PPVDDNTH
MAB_3678c|M.abscessus_ATCC_199      VLHDGFSVPFKQIADILGISDAAARQLASRARRMVTATP---EPVADAEH
MUL_3630|M.ulcerans_Agy99           VLHDVFAVPFDQIAPILERTPEATRKLASRARRRIERAEP-FPDRDLCAQ
TH_1142|M.thermoresistible__bu      VLREVFGFEYGEIATTVGKSVTAVRQIAHRARSHVHARRKRFEPVDPEVS
MLBr_01076|M.leprae_Br4923          YQPGTFEGWLHRITTNLFLD-----MVRRRARIRMDALP-----------
                                         *      ::  :         :  ***                  

Rv3328c|M.tuberculosis_H37Rv        NEVVGRLMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKV
Mb3361c|M.bovis_AF2122/97           NEVVGRLMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKV
MAV_4301|M.avium_104                DEVVGQLMAAMAAGNLEAVVALLHPDVMFTGDSNGKAPTAVQVIHGADKV
MMAR_1196|M.marinum_M               NEVVGRLMAAMASGDLHSVVSLLHPDVTFTGDANGRAPTAARVICGADKV
Mflv_4852|M.gilvum_PYR-GCK          AEVVGKLLAAMASGDLTAVVSLLHPDVTFTGDSNRRAPTAARVIRGSDKV
Mvan_1575|M.vanbaalenii_PYR-1       AEVVGKLLAAMASGDLTEVVAVLHPDVTFTGDSNRRAPTAARVIHGSDKV
MSMEG_1666|M.smegmatis_MC2_155      NEIAGALMAALAAGDMDGVVRLLHPDVTFTGDSNRKAPTAPRVIHGPEKV
MAB_3678c|M.abscessus_ATCC_199      NEVVGELLEALMSGSVEAVVRLLHPDVTMTGDSDGKAPTAVRVIHGPDKV
MUL_3630|M.ulcerans_Agy99           REVVDAFFAAGRSGNFERLVSVLHPDVVLRGDFGPNTPRFR--AQGAATV
TH_1142|M.thermoresistible__bu      MEITERFLTAASTGDMDGLLAMLAPDATWTADGGGKATAARRPIVGAEKV
MLBr_01076|M.leprae_Br4923          -DDYDRVPADEPNPEQIYHDSRLGPDLQAALDSLPPEFRAAVVLCDIEGL
                                     :    .       .       * **     *             .   :

Rv3328c|M.tuberculosis_H37Rv        VRFILGLVQRYGP-GLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRIT
Mb3361c|M.bovis_AF2122/97           VRFILGLVQRYGP-GLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRIT
MAV_4301|M.avium_104                VRFMLGLARRYGP-GFYSAYQLGLVNGELGIYTAGLPGGDGYREMCPRIM
MMAR_1196|M.marinum_M               ARFMLGLARRYGP-AFYTANQLALVNGELGSYTLGTAGDGGHWAMLPRIT
Mflv_4852|M.gilvum_PYR-GCK          ARFLLGLGAKYGPERLLAGSELGLVNGELGVYSPGADATPDAPRIMPRIQ
Mvan_1575|M.vanbaalenii_PYR-1       ARFLLGLARRYGEQRFFGSGVLGMVNGELGVYTMGAPATEDAPAIAPRIQ
MSMEG_1666|M.smegmatis_MC2_155      ARFLFGLARRYGP-NWLAGAQLALINGELGTYTPGAPAGDGYPELLPRIT
MAB_3678c|M.abscessus_ATCC_199      ARFLLGLMERYGP-QMTQAINPALVNGQFGMYLTETDTDPNFRPVLPRVS
MUL_3630|M.ulcerans_Agy99           AKLARSYAGPERT------VLNTLVNGAAGAVIS-------ISEQASAVM
TH_1142|M.thermoresistible__bu      AAVILGIFRAGQR--------LPDVRIETAIYNCAPAVVVYSRDNLEGVF
MLBr_01076|M.leprae_Br4923          SYEEIGAT----------------LGVKLGTVRSRIHR--GRQALRDYLL
                                         .                  :    .                  : 

Rv3328c|M.tuberculosis_H37Rv        AITVRDGKVCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN
Mb3361c|M.bovis_AF2122/97           AITVRDGKVCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN
MAV_4301|M.avium_104                AMTVREGKVCALWDIANPDKFTGSPL--------GR------
MMAR_1196|M.marinum_M               AMTVRDGKVCALWDIANPDKFSGSPLRDLVG-----------
Mflv_4852|M.gilvum_PYR-GCK          ALAVRDGLVVAIYDVANPDKFTASPLAR--------------
Mvan_1575|M.vanbaalenii_PYR-1       ALTVHRGQVVAIYDIANPDKFTASPLR---------------
MSMEG_1666|M.smegmatis_MC2_155      AMTVRDGKVCAVWDVANPDKFTGSPLGTAVRRP---------
MAB_3678c|M.abscessus_ATCC_199      AFTVRDGRVLAVWDVSNPDKFSGTPLREA-------------
MUL_3630|M.ulcerans_Agy99           RFLVRNGRIAAIDVLADPQRIATLDISGLSGPGG--------
TH_1142|M.thermoresistible__bu      TVEVVDGRITHFYAVRNPEKLAAVDTPRQISR----------
MLBr_01076|M.leprae_Br4923          TAHPRDGATTDATHVKSA------------------------
                                          *       : ..