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VDLIEKFEAERPRLLSVAHRILGSRHDAEDAVQSAWIRAQSAAPNRVDNAPGWLTTVTARLCLDQLRARE RHGEVPLTAEHISDTQFAADEEFLRREEVSRAVLVVLDELSPKQRVAYVLHDLFAVPFGDIAAVLDTTAV SAKKLASRARARLGAADPERAREVGSQLEIVEAFLSAARGGDIERLITLMAPDVIRTVDHTLIPSGAATL VRGAQAVAEETRSFTDRIAVAAILLIDGRVGAVIAPGGHPFALIRMDTDGRLVTCIDIAPYTSGDAALSL IATAGSKVSYSPGESGRRIDPRGSGLPRVDH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4733 | - | - | 100% (311) | putative RNA polymerase sigma factor |
| M. abscessus ATCC 19977 | MAB_3678c | - | 2e-32 | 39.56% (225) | RNA polymerase sigma factor SigJ |
| M. abscessus ATCC 19977 | MAB_2999c | sigI | 5e-28 | 34.78% (253) | RNA polymerase sigma factor SigI |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3361c | sigJ | 2e-31 | 35.25% (261) | RNA polymerase sigma factor SigJ |
| M. gilvum PYR-GCK | Mflv_1191 | - | 1e-66 | 53.88% (258) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv3328c | sigJ | 9e-32 | 36.26% (262) | RNA polymerase sigma factor SigJ |
| M. leprae Br4923 | MLBr_01076 | sigE | 2e-09 | 28.47% (144) | RNA polymerase sigma factor SigE |
| M. marinum M | MMAR_3687 | - | 2e-44 | 37.54% (293) | alternative RNA polymerase sigma factor SigJ-like protein |
| M. avium 104 | MAV_2475 | - | 1e-63 | 50.00% (292) | RNA polymerase sigma factor |
| M. smegmatis MC2 155 | MSMEG_1666 | - | 2e-34 | 36.84% (285) | RNA polymerase sigma factor SigJ |
| M. thermoresistible (build 8) | TH_1142 | - | 4e-24 | 31.25% (224) | RNA polymerase sigma factor, sigma-70 family protein |
| M. ulcerans Agy99 | MUL_3630 | - | 2e-45 | 37.88% (293) | alternative RNA polymerase sigma factor SigJ- like |
| M. vanbaalenii PYR-1 | Mvan_4710 | - | 5e-73 | 52.24% (268) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3361c|M.bovis_AF2122/97 ------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLRW
Rv3328c|M.tuberculosis_H37Rv ------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLRW
MSMEG_1666|M.smegmatis_MC2_155 --------MTTAARTDQFEALRPHLLAVAYRLTGTYADAEDIVQEAWIRW
TH_1142|M.thermoresistible__bu MTGSGAPSARGDEHAERFTHLRPLLFTIAYEILGSATEADDVLQESYLRW
Mflv_1191|M.gilvum_PYR-GCK -----------MITPSVFEATRPQLTAMAFRMLGSIHDAEDAVQSAWIKA
Mvan_4710|M.vanbaalenii_PYR-1 ---MTLDSFAQSAVHSAFLEGRPRLLSLAHRLLGSAHDAEDAVQTAWLRV
MAB_4733|M.abscessus_ATCC_1997 -----------MDLIEKFEAERPRLLSVAHRILGSRHDAEDAVQSAWIRA
MAV_2475|M.avium_104 ----MNAPRNLAELAQRFDDDRRHLRSVAFQLLGSLADADDAVQSAWLKA
MMAR_3687|M.marinum_M --------MTDPALLARFQAARPRLGALAYRMLGSLADAEDVVQEAWLRL
MUL_3630|M.ulcerans_Agy99 --------MTDPALLARFQAARPRLGALAYRMLGSLADAEDVVQEAWLRL
MLBr_01076|M.leprae_Br4923 -MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLIITNLLSP
: . ..:* : :
Mb3361c|M.bovis_AF2122/97 DSQD------TVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPEP
Rv3328c|M.tuberculosis_H37Rv DSPD------TVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPEP
MSMEG_1666|M.smegmatis_MC2_155 AGQE------APIENLQAWLTTVVSRLGLDRLRSAAHRRESYYGEWLPEP
TH_1142|M.thermoresistible__bu AEVDL-----AAVRDTKSYLAKLVSRQALNALRAGARRREDYVGPWLPEP
Mflv_1191|M.gilvum_PYR-GCK SIT-----ATDDLRNPAAYLTTVLTRECVDQLRMRQRRREEPLAA-----
Mvan_4710|M.vanbaalenii_PYR-1 AATP----GPRDIANPSAWLTTVVTRVCLDQLRDRSRRDVLSRRV-----
MAB_4733|M.abscessus_ATCC_1997 QSA-----APNRVDNAPGWLTTVTARLCLDQLRARERHGEVPLTA-----
MAV_2475|M.avium_104 SRA-----DFAAVDNLSGWFTTITAREALDQLRARKRRAELPLAAPEELD
MMAR_3687|M.marinum_M NATTDRPQGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELVGQLPDP
MUL_3630|M.ulcerans_Agy99 NATTDRPEGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELVGQLPDP
MLBr_01076|M.leprae_Br4923 TIMS-----HPPPSRDDDWVEPFDALQGTAVFDATGDKAT----------
:. . : : :
Mb3361c|M.bovis_AF2122/97 VVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPFA
Rv3328c|M.tuberculosis_H37Rv VVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPFA
MSMEG_1666|M.smegmatis_MC2_155 VVTGIDGNDPLNAVVAGEDARFAAMVVLEQLSPDQRVAFVLYDGFGVPFP
TH_1142|M.thermoresistible__bu LL--LEERDASADVVLAESVSMAMMVVLESLTPDERAVFVLREVFGFEYG
Mflv_1191|M.gilvum_PYR-GCK DMIPADTVAADEHYLRRESISRALMVVLDRLTPSQRVAYVLHDVFAVPFQ
Mvan_4710|M.vanbaalenii_PYR-1 QPVQTVAYAADEEFLHREDVARALMVLLGRLTPAQRAAYVLHDLFAVPFD
MAB_4733|M.abscessus_ATCC_1997 EHISDTQFAADEEFLRREEVSRAVLVVLDELSPKQRVAYVLHDLFAVPFG
MAV_2475|M.avium_104 RLAVAASSPADEDTLLAESVSTALLVVLDRLSPAQRVAFVLHDVFAMPFE
MMAR_3687|M.marinum_M IVDGVAAFDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDVFAVPFD
MUL_3630|M.ulcerans_Agy99 IVDGVAAFDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDVFAVPFD
MLBr_01076|M.leprae_Br4923 MPSWEELVRQHAARVYWLAYRLSGNQHDAEDLTQETFIRVFRSVQNYQPG
: : . : *: .
Mb3361c|M.bovis_AF2122/97 EVAEVLGTSEAAARQLASRARKAVTAQ---PALISGDPDPAHNEVVGRLM
Rv3328c|M.tuberculosis_H37Rv EVAEVLGTSEAAARQLASRARKAVTAQ---PALISGDPDPAHNEVVGRLM
MSMEG_1666|M.smegmatis_MC2_155 DIADVLGVSAASARQLASRARRAVADA---PPPVD---DNTHNEIAGALM
TH_1142|M.thermoresistible__bu EIATTVGKSVTAVRQIAHRARSHVHAR---RKRFEPVDPEVSMEITERFL
Mflv_1191|M.gilvum_PYR-GCK EIAETLGTSPASAKKHASRARERIHRTVQIPAAAT-----IDSAVVEAFL
Mvan_4710|M.vanbaalenii_PYR-1 RVADILGVTPAGAKKHASRARARLRPVEPPSTGAPGD--AVDREVVDAFL
MAB_4733|M.abscessus_ATCC_1997 DIAAVLDTTAVSAKKLASRARARLGAADPERAREVG----SQLEIVEAFL
MAV_2475|M.avium_104 TIAELLNRSPDAAKKLASRARARLHAAPAGPPRRDGHRIERHVEVVQAFL
MMAR_3687|M.marinum_M QIAPILERTPEATRKLASRARRRIERAEPFPDRDLC----AQREVVDAFF
MUL_3630|M.ulcerans_Agy99 QIAPILERTPEATRKLASRARRRIERAEPFPDRDLC----AQREVVDAFF
MLBr_01076|M.leprae_Br4923 TFEGWLHRITTNLFLDMVRRRARIRMD-------------ALPDDYDRVP
. : * * : .
Mb3361c|M.bovis_AF2122/97 AAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILGLV
Rv3328c|M.tuberculosis_H37Rv AAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILGLV
MSMEG_1666|M.smegmatis_MC2_155 AALAAGDMDGVVRLLHPDVTFTGDSNRKAPTAPRVIHGPEKVARFLFGLA
TH_1142|M.thermoresistible__bu TAASTGDMDGLLAMLAPDATWTADGGGKATAARRPIVGAEKVAAVILGIF
Mflv_1191|M.gilvum_PYR-GCK AAAAGGDTATMVALMADDCVRVADPTLLPAHTPAVVIGDSAVADETSLFI
Mvan_4710|M.vanbaalenii_PYR-1 RAAGGGDIVRMVALMAPDAVRIVDPELLPTGTAAVVTGATAIAEETRHFA
MAB_4733|M.abscessus_ATCC_1997 SAARGGDIERLITLMAPDVIRTVDHTLIPSGAATLVRGAQAVAEETRSFT
MAV_2475|M.avium_104 AASRGGDIAALLQLLAADVLRTVDPVLVPADVPTALRGATRVAQETRRFA
MMAR_3687|M.marinum_M AAGRSGNFERLVSVLHPDVVLRGD--FGPNTPRFRAQGAATVAKLARSYA
MUL_3630|M.ulcerans_Agy99 AAGRSGNFERLVSVLHPDVVLRGD--FGPNTPRFRAQGAATVAKLARSYA
MLBr_01076|M.leprae_Br4923 ADEPNPEQIYHDSRLGPDLQAALDSLPPEFRAAVVLCDIEGLSYEEIGAT
: : * * . :
Mb3361c|M.bovis_AF2122/97 QRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDGKV
Rv3328c|M.tuberculosis_H37Rv QRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDGKV
MSMEG_1666|M.smegmatis_MC2_155 RRYGPNWLAGAQLALINGELGTYTPGAPAGDGYPELLPRITAMTVRDGKV
TH_1142|M.thermoresistible__bu R-------AGQRLPDVRIETAIYNCAPAVVVYSRDNLEGVFTVEVVDGRI
Mflv_1191|M.gilvum_PYR-GCK DR-----------IRVSAPMLVDGRTVHVIAPGGHELAVIDITV-TDGRI
Mvan_4710|M.vanbaalenii_PYR-1 DR-----------IRASVRMRVSGREAHIIAPGGHPLGIIDIRC-SGGLI
MAB_4733|M.abscessus_ATCC_1997 DR-----------IAVAAILLIDGRVGAVIAPGGHPFALIRMDT-DGRLV
MAV_2475|M.avium_104 GR-----------ARAGAVMLIDGTPGIVIAARGRAQILLMIGIGADDRI
MMAR_3687|M.marinum_M GP-----------ERTVLNALVNGAAGAVISISEQASAVMGFLV-RNGRI
MUL_3630|M.ulcerans_Agy99 GP-----------ERTVLNTLVNGAAGAVISISEQASAVMRFLV-RNGRI
MLBr_01076|M.leprae_Br4923 LG-----------------VKLGTVRSRIHRGRQALRDYLLTAHPRDGAT
: .
Mb3361c|M.bovis_AF2122/97 CALWDIANPDKFTGSPLKERRAQPTGRGRHHRN---------------
Rv3328c|M.tuberculosis_H37Rv CALWDIANPDKFTGSPLKERRAQPTGRGRHHRN---------------
MSMEG_1666|M.smegmatis_MC2_155 CAVWDVANPDKFTGSPLGTAVRRP------------------------
TH_1142|M.thermoresistible__bu THFYAVRNPEKLAAVDTPRQISR-------------------------
Mflv_1191|M.gilvum_PYR-GCK ARIEITRTHPSGRR----------------------------------
Mvan_4710|M.vanbaalenii_PYR-1 TGITITPVCAADVLEPAAQPA---------------------------
MAB_4733|M.abscessus_ATCC_1997 TCIDIAPYTSGDAALSLIATAGSKVSYSPGESGRRIDPRGSGLPRVDH
MAV_2475|M.avium_104 HTIDITGDPERIRRAALALPPAVRFRNITT------------------
MMAR_3687|M.marinum_M AAIDVLADPQRIATLDISGLSGPGG-----------------------
MUL_3630|M.ulcerans_Agy99 AAIDVLADPQRIATLDISGLSGPGG-----------------------
MLBr_01076|M.leprae_Br4923 TDATHVKSA---------------------------------------