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TARLDDHTERFTMLRPLLFTIAYEILGSVTEADDVLQDSYLNWAKVDLAAVRDTKSYLAQLVTRQALKAQ RTSARRRESYVGPWLPEPLLLDDRDASADVVLAESVSMAMLVVLETLTPDERAVFVLHDVFGFDYAEISE AVGKSTAAVRQIAHRAREHVHARRKRFDPVDSDQAAEITQQFLTAASTGDMAGLVALLAPDVVTITDGGG LPGAARRPLVGAERVAGAIVRGMRRDLRFEIVTANGAPAVALRTDEDQLLGLVTLEIHDGRITSLYAIAN PDKLAALDGPRVITR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6817 | - | - | 100% (296) | RNA polymerase sigma factor, sigma-70 family protein |
| M. smegmatis MC2 155 | MSMEG_5444 | - | 4e-99 | 65.53% (293) | RNA polymerase sigma-70 factor protein |
| M. smegmatis MC2 155 | MSMEG_1692 | - | 2e-45 | 38.60% (285) | ECF-family protein RNA polymerase sigma factor |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3361c | sigJ | 3e-41 | 34.35% (294) | RNA polymerase sigma factor SigJ |
| M. gilvum PYR-GCK | Mflv_1927 | - | 9e-97 | 64.29% (294) | ECF subfamily RNA polymerase sigma-24 factor |
| M. tuberculosis H37Rv | Rv3328c | sigJ | 3e-41 | 34.35% (294) | RNA polymerase sigma factor SigJ |
| M. leprae Br4923 | MLBr_01076 | sigE | 7e-06 | 26.17% (149) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_4200 | - | 1e-109 | 69.15% (295) | putative sigma factor |
| M. marinum M | MMAR_4487 | - | 1e-100 | 63.95% (294) | alternative RNA polymerase sigma factor |
| M. avium 104 | MAV_1129 | - | 9e-99 | 63.55% (299) | sigma factor |
| M. thermoresistible (build 8) | TH_1142 | - | 1e-111 | 69.44% (301) | RNA polymerase sigma factor, sigma-70 family protein |
| M. ulcerans Agy99 | MUL_3630 | - | 4e-29 | 31.72% (290) | alternative RNA polymerase sigma factor SigJ- like |
| M. vanbaalenii PYR-1 | Mvan_5347 | - | 1e-107 | 66.78% (301) | ECF subfamily RNA polymerase sigma-24 factor |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3361c|M.bovis_AF2122/97 -------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLR
Rv3328c|M.tuberculosis_H37Rv -------------MEVSEFEALRQHLMSVAYRLTGTVADAEDIVQEAWLR
MSMEG_6817|M.smegmatis_MC2_155 -MTAR------LDDHTERFTMLRPLLFTIAYEILGSVTEADDVLQDSYLN
MAB_4200|M.abscessus_ATCC_1997 --MIN------SDEHAERFTLLRPLLFTIVYEILGSATESDDVLQDSYLR
TH_1142|M.thermoresistible__bu -MTGSGAPSARGDEHAERFTHLRPLLFTIAYEILGSATEADDVLQESYLR
Mvan_5347|M.vanbaalenii_PYR-1 -MTAS------TDEHGERFTVLRPLLFTIAYEILGSATESEDVLQDSYLR
MMAR_4487|M.marinum_M -MTPPS----HSDEHAERFTLLRPLLFTIAYEILGSATESDDVLQESYLR
MAV_1129|M.avium_104 MMTQAP----TGSEHADRFTLLRPLLFTIAYEMLGSATEADDVLQDSYLR
Mflv_1927|M.gilvum_PYR-GCK -MTAAP-----GDEHAERFTQLRPLLFTIAYEILGSATESDDVLQESYLR
MUL_3630|M.ulcerans_Agy99 ---------MTDPALLARFQAARPRLGALAYRMLGSLADAEDVVQEAWLR
MLBr_01076|M.leprae_Br4923 --------------MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRA
: * : . . .::
Mb3361c|M.bovis_AF2122/97 WDSQD------TVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPE
Rv3328c|M.tuberculosis_H37Rv WDSPD------TVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTGTWLPE
MSMEG_6817|M.smegmatis_MC2_155 WAKVDL-----AAVRDTKSYLAQLVTRQALKAQRTSARRRESYVGPWLPE
MAB_4200|M.abscessus_ATCC_1997 WAQVDL-----ATVRDTKSYLAQLVTRQALKALRTSVRRREDYIGPWLPE
TH_1142|M.thermoresistible__bu WAEVDL-----AAVRDTKSYLAKLVSRQALNALRAGARRREDYVGPWLPE
Mvan_5347|M.vanbaalenii_PYR-1 WADVDL-----ATVRDTKSYLAQLVTREALNALRARSRRREEYVGPWLPE
MMAR_4487|M.marinum_M WAAVDL-----SAVRDTKSYLAQLVTRQSLNALRAGARRREEYVGPWLPE
MAV_1129|M.avium_104 WSTVDL-----ATVRDTKSYLAQLVTRQALNALRAGARRREEYVGPWLPE
Mflv_1927|M.gilvum_PYR-GCK WAEVDL-----ATVTDTKAYLARLVTRQALNTLRAQSRRREDYVGPWLPE
MUL_3630|M.ulcerans_Agy99 LNATTDRPEGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELVGQLPD
MLBr_01076|M.leprae_Br4923 SPE--------------DLIITNLLSPTIMSHPPPS--RDDDWVEPFDAL
:: ::: :. * .
Mb3361c|M.bovis_AF2122/97 PVVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPF
Rv3328c|M.tuberculosis_H37Rv PVVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDGFAVPF
MSMEG_6817|M.smegmatis_MC2_155 P--LLLDDRDASADVVLAESVSMAMLVVLETLTPDERAVFVLHDVFGFDY
MAB_4200|M.abscessus_ATCC_1997 P--LLLDEHDGSADVLLAESVSMAMLILLETLTPDERAVFVLREVFGFGY
TH_1142|M.thermoresistible__bu P--LLLEERDASADVVLAESVSMAMMVVLESLTPDERAVFVLREVFGFEY
Mvan_5347|M.vanbaalenii_PYR-1 P--LLLDERDASADIVLAESVSMAMLVLLETLTPDERAVFVLREVFGFDY
MMAR_4487|M.marinum_M P--LLLDESDPSADLVLAESVSMAMLVLLETLTPDERAVFVLREVFGFDY
MAV_1129|M.avium_104 P--LLLDEQDPSTDVVLAESISMAMLVLLETLSPDERAVFVLREVFGFDY
Mflv_1927|M.gilvum_PYR-GCK P--LLT-EADPSADVVLAESVSMAMLVVLETLSPDERAVFVLREVFGFGH
MUL_3630|M.ulcerans_Agy99 PIVDGVAAFDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDVFAVPF
MLBr_01076|M.leprae_Br4923 Q-----------GTAVFDATGDKATMPSWEELVR-QHAARVYWLAYRLSG
: * : : * :: . * : .
Mb3361c|M.bovis_AF2122/97 AEVAEVLGTSEAAARQLASRARKAVTAQPALIS----GDPDPAHNEVVGR
Rv3328c|M.tuberculosis_H37Rv AEVAEVLGTSEAAARQLASRARKAVTAQPALIS----GDPDPAHNEVVGR
MSMEG_6817|M.smegmatis_MC2_155 AEISEAVGKSTAAVRQIAHRAREHVHARRKRFD----PVDSDQAAEITQQ
MAB_4200|M.abscessus_ATCC_1997 DEIAGAVSKSATAVRQIAHRAREHVHARRKRFD----PLDAKESTRIAEQ
TH_1142|M.thermoresistible__bu GEIATTVGKSVTAVRQIAHRARSHVHARRKRFE----PVDPEVSMEITER
Mvan_5347|M.vanbaalenii_PYR-1 DEIAGAVGRSTQAVRQIAHRAKEHVHARRKRFG----PVDSRRTTQITEQ
MMAR_4487|M.marinum_M DEIADAVGKPAPTVRQVAHRARAHIQARRKKYG----DVDPQRNAQLTAQ
MAV_1129|M.avium_104 DEIAEAVGKPAPTVRQVARRAREHVRARRKRHPGAGQAIDPKRNAELTAQ
Mflv_1927|M.gilvum_PYR-GCK DEIAATLGKSTAAVRQIAHRAREHVQSRRKRFE----PVDPKTSGEITMT
MUL_3630|M.ulcerans_Agy99 DQIAPILERTPEATRKLASRARRRIERAEPFPD-----RDLCAQREVVDA
MLBr_01076|M.leprae_Br4923 NQHDAEDLTQETFIRVFRSVQNYQPGTFEGWLH------------RITTN
: * . . .:.
Mb3361c|M.bovis_AF2122/97 LMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILG
Rv3328c|M.tuberculosis_H37Rv LMAAMAAGDLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFILG
MSMEG_6817|M.smegmatis_MC2_155 FLTAASTGDMAGLVALLAPDVVTITDGGGLPGAARRPLVGAERVAGAIVR
MAB_4200|M.abscessus_ATCC_1997 FLLATETGDVEGLMALLAPDATWIADGNGRAGAARRPLTGAGKLARIFAG
TH_1142|M.thermoresistible__bu FLTAASTGDMDGLLAMLAPDATWTADGGGKATAARRPIVGAEKVAAVILG
Mvan_5347|M.vanbaalenii_PYR-1 FLTAAATGDMEELVSMLAPGATWTADHGGKATAVRRPVVGARKVAAIMAR
MMAR_4487|M.marinum_M FLQTAASGDVEALMAMLAPDATWLADSGGKVSAARKPVVGAERVARAITG
MAV_1129|M.avium_104 FLATAASGDVEALMAMLAPDATWTADSGGVVSAARRPVVGAEKVARAITG
Mflv_1927|M.gilvum_PYR-GCK FFAAAATGDLDALMAMLAPDVVWTADSDGKVSAARRPVEGADKVARLILG
MUL_3630|M.ulcerans_Agy99 FFAAGRSGNFERLVSVLHPDVVLRGDFG--PNTPRFRAQGAATVAKLARS
MLBr_01076|M.leprae_Br4923 LFLDMVRRRARIRMDALPDDYDRVPADEPNPEQIYHDSRLGPDLQAALDS
:: : * . . :
Mb3361c|M.bovis_AF2122/97 LVQRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDG
Rv3328c|M.tuberculosis_H37Rv LVQRYGPGLFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITVRDG
MSMEG_6817|M.smegmatis_MC2_155 GMRR-----DLRFEIVTANGAPAVALRTDE------DQLLGLVTLEIHDG
MAB_4200|M.abscessus_ATCC_1997 PFRKG--MADRRTEIVIANAAPAVAVYAG-------DALEVVITMEIADG
TH_1142|M.thermoresistible__bu IFRAGQRLPDVRIETAIYNCAPAVVVYSR-------DNLEGVFTVEVVDG
Mvan_5347|M.vanbaalenii_PYR-1 VFQAVRKTPQMRLETAVYNSAPAVVVYTE-------DHLEGVLLFEVVDD
MMAR_4487|M.marinum_M LIRKAAT--ELQVELVTCNSAPAVLFYLG-------GQLEGVITLEIVGD
MAV_1129|M.avium_104 LFRKAAEYATLRVDTVTCNGAPAVLLYLG-------DRLEGVITVEIAAD
Mflv_1927|M.gilvum_PYR-GCK FVRLAG--GEARVEPAFYNSAPALVLYTG-------DVLEGVVTFEVADG
MUL_3630|M.ulcerans_Agy99 YAGP-----ERTVLNTLVNGAAGAVISIS-------EQASAVMRFLVRNG
MLBr_01076|M.leprae_Br4923 LPPEFRAAVVLCDIEGLSYEEIGATLGVK----------LGTVRSRIHRG
. : .
Mb3361c|M.bovis_AF2122/97 K--VCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN
Rv3328c|M.tuberculosis_H37Rv K--VCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN
MSMEG_6817|M.smegmatis_MC2_155 R--ITSLYAIANPDKLAALDGPRVITR----------
MAB_4200|M.abscessus_ATCC_1997 K--ITRLYAVANPDKLVAAATTRMVSR----------
TH_1142|M.thermoresistible__bu R--ITHFYAVRNPEKLAAVDTPRQISR----------
Mvan_5347|M.vanbaalenii_PYR-1 K--ITNLYAMRNPDKLTGITIPRKITR----------
MMAR_4487|M.marinum_M K--ITNFYVMRNPDKLTAVARAHEISRG---------
MAV_1129|M.avium_104 K--ITNFYVMRNPHKLAALATARDVSRG---------
Mflv_1927|M.gilvum_PYR-GCK R--ITNFYAMRNPEKLTGVMVARTISR----------
MUL_3630|M.ulcerans_Agy99 R--IAAIDVLADPQRIATLDISGLSGPGG--------
MLBr_01076|M.leprae_Br4923 RQALRDYLLTAHPRDGATTDATHVKSA----------
: : .* .