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TSPDAADLTARFEAARPRLGALAYRMLGSIDDAQDAVQEAWLRLDRSGGADIANLDAWLTTVVARICLNM LRDRRTRDGAEPAAHLPDPIVEPAGEFDPEHRAMLADAVGMALFVVLDTLPPAERLAFVLHDVFAVPFAQ IAAIVDGTPESARKLASRARRRIERADPVPDGDLAAQREVVDAFFAAGRSGDFDRLVSVLHPDVVLRGDF GPATATVRVQGAAAVAKLARSYAGPEREACAATVNGAAGAVIFVAGRAASVMGFVVRGGRIRAIDVLADP DRIAKLELGALRADH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2018 | - | - | 100% (296) | RNA polymerase ECF-subfamily protein sigma factor |
| M. avium 104 | MAV_2475 | - | 1e-48 | 40.07% (297) | RNA polymerase sigma factor |
| M. avium 104 | MAV_4301 | - | 2e-41 | 38.36% (305) | RNA polymerase sigma factor SigJ |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3361c | sigJ | 2e-42 | 39.74% (302) | RNA polymerase sigma factor SigJ |
| M. gilvum PYR-GCK | Mflv_4852 | - | 4e-43 | 39.53% (296) | RNA polymerase sigma factor SigJ |
| M. tuberculosis H37Rv | Rv3328c | sigJ | 2e-42 | 39.74% (302) | RNA polymerase sigma factor SigJ |
| M. leprae Br4923 | MLBr_01076 | sigE | 2e-09 | 31.33% (166) | RNA polymerase sigma factor SigE |
| M. abscessus ATCC 19977 | MAB_4733 | - | 2e-51 | 41.97% (274) | putative RNA polymerase sigma factor |
| M. marinum M | MMAR_3687 | - | 1e-115 | 73.40% (297) | alternative RNA polymerase sigma factor SigJ-like protein |
| M. smegmatis MC2 155 | MSMEG_1666 | - | 2e-41 | 39.60% (298) | RNA polymerase sigma factor SigJ |
| M. thermoresistible (build 8) | TH_1144 | - | 1e-31 | 31.93% (285) | RNA polymerase sigma factor, sigma-70 family protein |
| M. ulcerans Agy99 | MUL_3630 | - | 1e-113 | 72.73% (297) | alternative RNA polymerase sigma factor SigJ- like |
| M. vanbaalenii PYR-1 | Mvan_1575 | - | 3e-44 | 39.79% (289) | RNA polymerase sigma factor SigJ |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3687|M.marinum_M -------MTDP---ALLARFQAARPRLGALAYR----MLGSLADAEDVVQ
MUL_3630|M.ulcerans_Agy99 -------MTDP---ALLARFQAARPRLGALAYR----MLGSLADAEDVVQ
MAV_2018|M.avium_104 -------MTSPDAADLTARFEAARPRLGALAYR----MLGSIDDAQDAVQ
MAB_4733|M.abscessus_ATCC_1997 -------------MDLIEKFEAERPRLLSVAHR----ILGSRHDAEDAVQ
Mb3361c|M.bovis_AF2122/97 --------------MEVSEFEALRQHLMSVAYR----LTGTVADAEDIVQ
Rv3328c|M.tuberculosis_H37Rv --------------MEVSEFEALRQHLMSVAYR----LTGTVADAEDIVQ
MSMEG_1666|M.smegmatis_MC2_155 ----------MTTAARTDQFEALRPHLLAVAYR----LTGTYADAEDIVQ
Mflv_4852|M.gilvum_PYR-GCK MPHGGIYTRRMTASARVAEFEQMRPHLLSVAYR----LTGTVADAEDIVQ
Mvan_1575|M.vanbaalenii_PYR-1 ----------MTTSARVGEFEQLRPHLLSVAYR----LTGTLADAEDIVQ
TH_1144|M.thermoresistible__bu --VTVGSAAGAADGEHAERFTLLRPLLFTIAYE----ILGSATEADDVLQ
MLBr_01076|M.leprae_Br4923 -------MGDGIGMEREGRWTGNTQCPLRVVPGDESPTLDGRASPEDLII
.: :. . ..:* :
MMAR_3687|M.marinum_M EAWLRLNATTDRPQGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELV
MUL_3630|M.ulcerans_Agy99 EAWLRLNATTDRPEGAQELVNLDAWLTTVVARLCLNLLRDRRGRGREELV
MAV_2018|M.avium_104 EAWLRLDRS-----GGADIANLDAWLTTVVARICLNMLRDRRTRDGAEPA
MAB_4733|M.abscessus_ATCC_1997 SAWIRAQSA-----APNRVDNAPGWLTTVTARLCLDQLRARERHGEVPLT
Mb3361c|M.bovis_AF2122/97 EAWLRWDSQ------DTVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTG
Rv3328c|M.tuberculosis_H37Rv EAWLRWDSP------DTVIADPRAWLTTVVSRLGLDKLRSAAHRRETYTG
MSMEG_1666|M.smegmatis_MC2_155 EAWIRWAGQ------EAPIENLQAWLTTVVSRLGLDRLRSAAHRRESYYG
Mflv_4852|M.gilvum_PYR-GCK DAWLRWSTHR-----GAAVEDLKAWLTTVVSRLALDKLRSAAHRRETYVG
Mvan_1575|M.vanbaalenii_PYR-1 DAWLRWEANS-----ATVIEDLKAWLTTVVSRLALDRLRSAAHRRETYVG
TH_1144|M.thermoresistible__bu DGYLRWSQVD-----LGTVRDTKAFLAQLITREALKVLRTRSRRREDYVG
MLBr_01076|M.leprae_Br4923 TNLLSPTIMS-----HPPPSRDDDWVEPFDALQGTAVFDATGDKATMPSW
: :: . : : :
MMAR_3687|M.marinum_M GQLPDPIVDGVAAFDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDV
MUL_3630|M.ulcerans_Agy99 GQLPDPIVDGVAAFDPEHHAMLADAVGLALFVVLDTLAPAERLAFVLHDV
MAV_2018|M.avium_104 AHLPDPIVEPAGEFDPEHRAMLADAVGMALFVVLDTLPPAERLAFVLHDV
MAB_4733|M.abscessus_ATCC_1997 ---AEHISD--TQFAADEEFLRREEVSRAVLVVLDELSPKQRVAYVLHDL
Mb3361c|M.bovis_AF2122/97 TWLPEPVVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDG
Rv3328c|M.tuberculosis_H37Rv TWLPEPVVTGLDATDPLAAVVAAEDARFAAMVVLERLRPDQRVAFVLHDG
MSMEG_1666|M.smegmatis_MC2_155 EWLPEPVVTGIDGNDPLNAVVAGEDARFAAMVVLEQLSPDQRVAFVLYDG
Mflv_4852|M.gilvum_PYR-GCK EWLPEPVVTGLDGRDPLSALVADEDARFAAMVVLENLTPDQRVAFVLHDG
Mvan_1575|M.vanbaalenii_PYR-1 EWLPEPVVTGFDGVDPLASVVAGEDARFAAMVVLENLTPDQRVAFVLHDG
TH_1144|M.thermoresistible__bu PWLPEPLL--LEDHDPESDVVLAESVSMAMLVLLETLSPDERAVFVLREV
MLBr_01076|M.leprae_Br4923 EELVRQHAARVYWLAYRLSGNQHDAEDLTQETFIR----------VFRSV
: : ..: *: .
MMAR_3687|M.marinum_M FAVPFDQIAPILERTPEATRKLASRARRRIERAEPFPDRD-LCAQREVVD
MUL_3630|M.ulcerans_Agy99 FAVPFDQIAPILERTPEATRKLASRARRRIERAEPFPDRD-LCAQREVVD
MAV_2018|M.avium_104 FAVPFAQIAAIVDGTPESARKLASRARRRIERADPVPDGD-LAAQREVVD
MAB_4733|M.abscessus_ATCC_1997 FAVPFGDIAAVLDTTAVSAKKLASRARARLGAADPERARE-VGSQLEIVE
Mb3361c|M.bovis_AF2122/97 FAVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALISGDPDPAHNEVVG
Rv3328c|M.tuberculosis_H37Rv FAVPFAEVAEVLGTSEAAARQLASRARKAVTAQPALISGDPDPAHNEVVG
MSMEG_1666|M.smegmatis_MC2_155 FGVPFPDIADVLGVSAASARQLASRARRAVADAPPPVD---DNTHNEIAG
Mflv_4852|M.gilvum_PYR-GCK FAVPFSAIAEVLGTSTQAARQLASRARRAVSSAPPPAA-----DHAEVVG
Mvan_1575|M.vanbaalenii_PYR-1 FAVPFAEIAEVLGSSPESARQLASRARRAASAAPPPAD-----EHAEVVG
TH_1144|M.thermoresistible__bu FDFDYDEIAGAVGKSVPAVRQVAHRSREHVRARRKRFDPVPAAQTTELAE
MLBr_01076|M.leprae_Br4923 QNYQPGTFEGWLHRITTNLFLDMVRRRARIRMDALPDDYDRVPADEPNPE
. : * *
MMAR_3687|M.marinum_M AFFAAGRSG-NFERLVSVLHPDVVLRGDFG--PNTPRFRAQGAATVAKLA
MUL_3630|M.ulcerans_Agy99 AFFAAGRSG-NFERLVSVLHPDVVLRGDFG--PNTPRFRAQGAATVAKLA
MAV_2018|M.avium_104 AFFAAGRSG-DFDRLVSVLHPDVVLRGDFG--PATATVRVQGAAAVAKLA
MAB_4733|M.abscessus_ATCC_1997 AFLSAARGG-DIERLITLMAPDVIRTVDHTLIPSGAATLVRGAQAVAEET
Mb3361c|M.bovis_AF2122/97 RLMAAMAAG-DLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFI
Rv3328c|M.tuberculosis_H37Rv RLMAAMAAG-DLDTVVSLLHPDVTFTGDSNGKAPTAVRAVRGSDKVVRFI
MSMEG_1666|M.smegmatis_MC2_155 ALMAALAAG-DMDGVVRLLHPDVTFTGDSNRKAPTAPRVIHGPEKVARFL
Mflv_4852|M.gilvum_PYR-GCK KLLAAMASG-DLTAVVSLLHPDVTFTGDSNRRAPTAARVIRGSDKVARFL
Mvan_1575|M.vanbaalenii_PYR-1 KLLAAMASG-DLTEVVAVLHPDVTFTGDSNRRAPTAARVIHGSDKVARFL
TH_1144|M.thermoresistible__bu EFIHAATTG-DLDRLLSLLAPGATFTTDHGGKAPAVARPVEGAKKVANLV
MLBr_01076|M.leprae_Br4923 QIYHDSRLGPDLQAALDSLPPEFR--------AAVVLCDIEGLS------
: * :: : : * . .*
MMAR_3687|M.marinum_M RSYAG-------------PERTVLNALVNGAAGAVISISEQASAVMGFLV
MUL_3630|M.ulcerans_Agy99 RSYAG-------------PERTVLNTLVNGAAGAVISISEQASAVMRFLV
MAV_2018|M.avium_104 RSYAG-------------PEREACAATVNGAAGAVIFVAGRAASVMGFVV
MAB_4733|M.abscessus_ATCC_1997 RSFTD-------------RIAVAAILLIDGRVGAVIAPGGHPFALIRMDT
Mb3361c|M.bovis_AF2122/97 LGLVQRYGPG-LFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITV
Rv3328c|M.tuberculosis_H37Rv LGLVQRYGPG-LFGANQLALVNGELGAYTAGLPGVDGYRAMAPRITAITV
MSMEG_1666|M.smegmatis_MC2_155 FGLARRYGPN-WLAGAQLALINGELGTYTPGAPAGDGYPELLPRITAMTV
Mflv_4852|M.gilvum_PYR-GCK LGLGAKYGPERLLAGSELGLVNGELGVYSPGADATPDAPRIMPRIQALAV
Mvan_1575|M.vanbaalenii_PYR-1 LGLARRYGEQRFFGSGVLGMVNGELGVYTMGAPATEDAPAIAPRIQALTV
TH_1144|M.thermoresistible__bu MGFFR--------NRHRVPDLRLEATNCNHAPAVLVYTGDHLEAVVLLEI
MLBr_01076|M.leprae_Br4923 -----------------YEEIGATLGVKLGTVRSRIHRGRQALRDYLLTA
:
MMAR_3687|M.marinum_M RNGRIAAIDVLADPQRIATLDISGLSGPGG--------------------
MUL_3630|M.ulcerans_Agy99 RNGRIAAIDVLADPQRIATLDISGLSGPGG--------------------
MAV_2018|M.avium_104 RGGRIRAIDVLADPDRIAKLELGALRADH---------------------
MAB_4733|M.abscessus_ATCC_1997 DGRLVTCIDIAPYTSGDAALSLIATAGSKVSYSPGESGRRIDPRGSGLPR
Mb3361c|M.bovis_AF2122/97 RDGKVCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN------------
Rv3328c|M.tuberculosis_H37Rv RDGKVCALWDIANPDKFTGSPLKERRAQPTGRGRHHRN------------
MSMEG_1666|M.smegmatis_MC2_155 RDGKVCAVWDVANPDKFTGSPLGTAVRRP---------------------
Mflv_4852|M.gilvum_PYR-GCK RDGLVVAIYDVANPDKFTASPLAR--------------------------
Mvan_1575|M.vanbaalenii_PYR-1 HRGQVVAIYDIANPDKFTASPLR---------------------------
TH_1144|M.thermoresistible__bu VDGAITNLYATRNPDKLAAVAAPRTITR----------------------
MLBr_01076|M.leprae_Br4923 HPRDGATTDATHVKSA----------------------------------
.
MMAR_3687|M.marinum_M ---
MUL_3630|M.ulcerans_Agy99 ---
MAV_2018|M.avium_104 ---
MAB_4733|M.abscessus_ATCC_1997 VDH
Mb3361c|M.bovis_AF2122/97 ---
Rv3328c|M.tuberculosis_H37Rv ---
MSMEG_1666|M.smegmatis_MC2_155 ---
Mflv_4852|M.gilvum_PYR-GCK ---
Mvan_1575|M.vanbaalenii_PYR-1 ---
TH_1144|M.thermoresistible__bu ---
MLBr_01076|M.leprae_Br4923 ---