For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MTQKRNLRAGVEDRWNKTVRDEHGNPQTVPSATYGKGKRWRARYVDEQGREHVQSFTRKVDAQQWLTNQT ATIVAGTHVAPRDAKLTVQQWCDTWIEGYKVHREGTVREARTHIRQIVTEFGDTPLTQVRPSQVKAWTAR LRADGMKASYIYALHSRLSQIMADAVHDGVLGRNPCSRRTAPPMGKAKVYVATTEQVWALHDAVPDHLKV AVLLGAFAGLRVAEVSGLRVSDVDFIRGVVHPKQQWSDKPLKTEGSSAPIPIPQDLALLLSASVQKYPAE MMVTNGLGTDRCGPWIIERAIRDVRRGIDGLPEGFSFHDLRHYLASLLIARGCDVKTVQARLRHSSAKTT LDTYSHLWPDADESTRSAIGAVLAERVDSGETTADELRTMRPGRGRRRRSGV
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2266 | - | - | 100% (402) | phage-related integrase |
| M. avium 104 | MAV_2217 | - | 1e-66 | 39.55% (397) | traSA:integrase fusion protein |
| M. avium 104 | MAV_1484 | - | 5e-18 | 25.00% (372) | integrase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3777 | - | 2e-06 | 55.56% (45) | putative integrase (fragment) |
| M. gilvum PYR-GCK | Mflv_2927 | - | 1e-165 | 72.09% (387) | phage integrase family protein |
| M. tuberculosis H37Rv | Rv2659c | - | 2e-18 | 25.41% (370) | phiRv2 prophage integrase |
| M. leprae Br4923 | MLBr_01600 | xerC | 3e-07 | 24.45% (274) | site-specific tyrosine recombinase XerC |
| M. abscessus ATCC 19977 | MAB_3204c | xerC | 2e-07 | 24.69% (243) | site-specific tyrosine recombinase XerC |
| M. marinum M | MMAR_4848 | - | 2e-11 | 25.15% (342) | prophage integrase |
| M. smegmatis MC2 155 | MSMEG_5754 | - | 4e-12 | 25.64% (390) | gp41 protein |
| M. thermoresistible (build 8) | TH_0846 | xerC | 8e-09 | 25.20% (246) | PROBABLE INTEGRASE/RECOMBINASE XERC |
| M. ulcerans Agy99 | MUL_0529 | - | 1e-13 | 25.58% (301) | prophage integrase |
| M. vanbaalenii PYR-1 | Mvan_4364 | - | 3e-18 | 28.11% (338) | phage integrase family protein |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_2266|M.avium_104 MTQKRNLRAGVEDRWNKTVRDEHGNPQTVPSATYGKGKRWRARYVDEQGR
Mflv_2927|M.gilvum_PYR-GCK -MQRRNRRSGVEDRWRKTVTRPDGTTERVPSARDGKGLRWLARYVDERGR
MMAR_4848|M.marinum_M --MAGSVPRGIRKRTNSAGQARYQVRYLVRDPNSPSG--WVETSSTFATM
MUL_0529|M.ulcerans_Agy99 --MAGNTPRGIRKRLNAAGEPRYQVRYLIRDPDAPSG--WVETSATFPTL
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01600|M.leprae_Br4923 -------------------------------------------MAILDEF
TH_0846|M.thermoresistible__bu ----------------------------------------MSVDTVLDEF
MAB_3204c|M.abscessus_ATCC_199 --------------------------------------MTPQLAAILDEF
Rv2659c|M.tuberculosis_H37Rv MTQTGKRQRRKFGRIRQFNSGRWQASYTGPDGRVYIAPKTFNAKIDAEAW
Mvan_4364|M.vanbaalenii_PYR-1 --MAGKKGHRGWGWIRQLPSKRYQASYIGPDLIRHKASTTFGARIDAEGW
MSMEG_5754|M.smegmatis_MC2_155 MLQRMARIPDYVKVIDLDSGRRYEVRPEVTGADGKRRQKRERFKTLKEAV
MAV_2266|M.avium_104 EHVQSFTRKVDAQQWLTNQTATIVAGTHVAPRDAKLTVQQWCDTWIEG--
Mflv_2927|M.gilvum_PYR-GCK EHSKSFARKPDAQQWLDGQTAAVVTGSHVAPRTAQMTVEQWCDTWIGG--
MMAR_4848|M.marinum_M REARAFKADRDGEAAIG--------ARRFDPRLGRASLSAIWTQYSASK-
MUL_0529|M.ulcerans_Agy99 REAKAFKSERDNEAALG--------ARRFDPRLGRTPLSRIWTQFSDSK-
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01600|M.leprae_Br4923 DEHLALRCGRS---------------------------------------
TH_0846|M.thermoresistible__bu ADYLALQRGRS---------------------------------------
MAB_3204c|M.abscessus_ATCC_199 AEHLALERGRS---------------------------------------
Rv2659c|M.tuberculosis_H37Rv LTDRRREIDRQLWSP-----------ASGQEDRPGAPFGEYAEGWLKQ--
Mvan_4364|M.vanbaalenii_PYR-1 LSQERRSIELDTWTPPA--------QRAAEVKAKAVTLGEYSTKWIED--
MSMEG_5754|M.smegmatis_MC2_155 DHYTAIAGDRGRGVHVAPSELTVEDAVDSWLLGQRIRPKTMSAYITSLRP
MAV_2266|M.avium_104 ----YKVHREGTVREARTHIRQIVTEFGDTPLTQVRPSQVKAWTARLRAD
Mflv_2927|M.gilvum_PYR-GCK ----YAVNRESTVRQARTHIKHIVAEFGDQPLSALRPSQVKAWVAGLKKA
MMAR_4848|M.marinum_M ---QPAVSPKTWSGYAQHWELRISPRFGHVPVDEISRKDVQQFIGGLTVG
MUL_0529|M.ulcerans_Agy99 ---KPAVSPKTWSGYNQHWELRIKPRFGHVPVDEITRADVRAFVDGLTVG
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01600|M.leprae_Br4923 -----EHTRRAYLGDLRSLLTHLEGR--GSRLDQLSLPVLRSWLATAAGA
TH_0846|M.thermoresistible__bu -----PHTCRAYLGDLRSLFDFVEQRSPGSGLGGLSLPVLRAWLAAQAAD
MAB_3204c|M.abscessus_ATCC_199 -----VHTQRAYRGDLTLLFDHLSASNPEATLADLSLPVLRSWLGAQARQ
Rv2659c|M.tuberculosis_H37Rv ----RGIKDRTRAHYRKLLDNHILATFADTDLRDITPAAVRRWYATTAVG
Mvan_4364|M.vanbaalenii_PYR-1 ----RNVKPRTRSSYRDILRLHIEPRLGSMAMKNLTGEVVRSWYAGLGTD
MSMEG_5754|M.smegmatis_MC2_155 IVDHLGKRTVQSITKDDLEQVVQALRAGTSKMGTWNAPTKLTKAAKKVRS
MAV_2266|M.avium_104 GMKASYIYALHSRLSQIMADAVHDGVLGRNPCSRRTAPPMGKAKVYVATT
Mflv_2927|M.gilvum_PYR-GCK DVAPSYVYALHSRLSQICGDAVHDGVLARNPCSRRTAPPMGTQKPYVATT
MMAR_4848|M.marinum_M ---PWAKLATLRLLRSILDMAREDGRIHINPAQGVSSGRIPARERHRYLS
MUL_0529|M.ulcerans_Agy99 ---PWAKVSTLRLLRSILDVAHQDGRIHRNPALGVSAGRIPERERHRYLT
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01600|M.leprae_Br4923 GAARTTLARRISAVKAFTAWAKWRGQLAADPAARLQVPRAYRTLPAVLRQ
TH_0846|M.thermoresistible__bu GSARTTLARRTSAVKTFTAWAVRQGLLSTDPALRLQVPKARRTLPAVLRR
MAB_3204c|M.abscessus_ATCC_199 GAARSTVARRTSAVKIFTAWATRRGLLPTDPAIRLQQPKSRRTLPAVLRQ
Rv2659c|M.tuberculosis_H37Rv --TPTMRAHSYSLLRAIMQTALADDLIDSNPCRISGAS-TARRVHKIRPA
Mvan_4364|M.vanbaalenii_PYR-1 --YPRRNSHAYGLLHAVCATAVSDGLLQSNPCNIRRAMNPPRRRDPVILA
MSMEG_5754|M.smegmatis_MC2_155 PWAASSINPMLARTRSIFEDLVNQGVVVRNVAALVKPLATDTEKTMNTLN
MAV_2266|M.avium_104 EQVWALHDAVPD----------HLKVAVLLGAFAGLRVAEVSGLRVSDVD
Mflv_2927|M.gilvum_PYR-GCK EQVWALHDAMPD----------HLRVAVLLGAFVGLRVAEVAALRVSDVD
MMAR_4848|M.marinum_M ATEVAALAHACG----------DQGDIVTILAFTGLRWSELVGLRVGDID
MUL_0529|M.ulcerans_Agy99 AQEVRMLATACG----------DQGDVVTILAYTGLRWSEPVGLRVKDID
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01600|M.leprae_Br4923 DQALQIMAAAKSGAEQGDPLALRDRLIVEMLYATGIRVSELCGLDIDDVD
TH_0846|M.thermoresistible__bu DQALAAMAAADSGAQQKDPIALRDRLIVEMLYATGIRVSELCGLDIDDVD
MAB_3204c|M.abscessus_ATCC_199 DQAAAAMEAAHSGAEQDDPMALRDRLIVEMLYATGIRVSELCGLDIDDID
Rv2659c|M.tuberculosis_H37Rv TLDELETITKAMPD--------PYQAFVLMAAWLAMRYGELTELRRKDID
Mvan_4364|M.vanbaalenii_PYR-1 VADIAALAEAIQPR--------RLRCLVLLAAWCGVRWGEVSELRRKDLS
MSMEG_5754|M.smegmatis_MC2_155 AEQVTQLLAVTDS---------HCYGIAWRLAVLGLRRGEILALRWDAVD
MAV_2266|M.avium_104 FIRGVVHPKQQWSD-------KPLKTEGSSAPIPIP----QDLALLLSAS
Mflv_2927|M.gilvum_PYR-GCK FIRGVVHPVQQWPD-------KPLKTDGSAQPVPIP----NDLALLLSAS
MMAR_4848|M.marinum_M LKARRLYVRQAAPDVEGRIIVGPPKTRAAVRTVPLP----RIVIDALKPR
MUL_0529|M.ulcerans_Agy99 LTARRLYVRRAAPEVEGHIVIGPPKTRAGIRTVPLP----QVVVDIFKGR
Mb3777|M.bovis_AF2122/97 --------------------------------------------------
MLBr_01600|M.leprae_Br4923 TRHRLVRVLGKGNK--------QRTAPFGVPAADAL----RGWLDDGRPA
TH_0846|M.thermoresistible__bu TDRHLARVLGKGGR--------QRTVPFGEPARGAL----TDWLTDGRPA
MAB_3204c|M.abscessus_ATCC_199 RPRKVLRVLGKGDK--------ERTVPFGDPAADAL----SAWLDRGRPH
Rv2659c|M.tuberculosis_H37Rv LHGEVARVRRAVVRVGEGFKVTTPKSDAGVRDISIPPHLIPAIEDHLHKH
Mvan_4364|M.vanbaalenii_PYR-1 DGCEVLSVSRAVTRRDGVYRVDTPKSGKG-RAVVIPPHIREDVINHLAEN
MSMEG_5754|M.smegmatis_MC2_155 FDAGTLAISAARLATAGGATTGAPKTKTSVRTLPMPEDLTAALRRVRKRQ
MAV_2266|M.avium_104 VQKYPAE-----MMVTNGLGTDRCGPWIIERAIRDVRRGIDGLPEGFSFH
Mflv_2927|M.gilvum_PYR-GCK VKRYPSP-----MMVTRGVAGETAPPWVIEREVRAARSSIDGLPEEFSFH
MMAR_4848|M.marinum_M IENRSTK-----EQAITSPNGGFLRSNNWRRHTHWNKALKKTGLAPLTIH
MUL_0529|M.ulcerans_Agy99 ITGQAPD-----QPAVTSTNGAMLRSNNWRRHTHWNKALKSTDLAPLTIH
Mb3777|M.bovis_AF2122/97 --------------------------------------MKRAKVQQITPH
MLBr_01600|M.leprae_Br4923 LVTVESG-----PALLLGSRGRRLDVRQARTVVHQTVAVVAG-APDMGPH
TH_0846|M.thermoresistible__bu LATAESG-----PALLLGVRGRRLDPRQARTVVHQTVAAVAG-APDIGPH
MAB_3204c|M.abscessus_ATCC_199 LAVPASG-----AALLLGARGRRVDPRQVRTVVHQTMSAVPG-APDIGPH
Rv2659c|M.tuberculosis_H37Rv VNPGRES-----LLFPSVNDPNRHLAPSALYRMFY-KARKAAGRPDLRVH
Mvan_4364|M.vanbaalenii_PYR-1 VESGPES-----LLFPAARG--GHMNDRVFSREYFSDALKAIGRQGVRVH
MSMEG_5754|M.smegmatis_MC2_155 KEYRLKLGSKWTDSGYVVVDEFGVAPYPDTLTAAWRKTLANAGLPHVRLH
. *
MAV_2266|M.avium_104 DLRHYLASLLIARGCDVKTVQARLRHSSAKTTLDTYSHLWPDADESTRSA
Mflv_2927|M.gilvum_PYR-GCK DLRHYLASLLIASGADIKTVQARMRHGSARTTLDTYGHLWPDADESTRTA
MMAR_4848|M.marinum_M DLRHTYASLARKSGADLRYVQKTMGHSTPTVTANIYSDLYSDELDHVATN
MUL_0529|M.ulcerans_Agy99 DLRHTYASLARKSGADLRYVQKTMGHSTPTVTANIYSDLYADELDQVATN
Mb3777|M.bovis_AF2122/97 DLRHTAASLAVSAGVNVLALQRILGHKSAKVTLDTYADLFDADLDAVAVT
MLBr_01600|M.leprae_Br4923 GLRHSAATHLLEGGADLRVVQELLGHSS-LATTQLYTHVAVSRLRVVHDQ
TH_0846|M.thermoresistible__bu GLRHSAATHLLEGGADLRIVQELLGHTS-LATTQLYTHVTVERLRAVHDQ
MAB_3204c|M.abscessus_ATCC_199 GLRHSAATHLLEGGADLRVVQELLGHST-LATTQLYTHVTVARLRAVHDQ
Rv2659c|M.tuberculosis_H37Rv DLRHSGAVLAASTGATLAELMQRLGHST-AGAALRYQHAAKGRDREIAAL
Mvan_4364|M.vanbaalenii_PYR-1 DLRHFAGTQTAQV-ANLAESMARLGHST-VKASLIYQGLVTGRDAAIADA
MSMEG_5754|M.smegmatis_MC2_155 DARHSCATLMHLSGVPTVVIAAWLGHQDPGFTLRTYAHSNHDALADAAAM
. ** . : * : *
MAV_2266|M.avium_104 IGAVLAERVDSGETTADELRTMRPGRGRRRRSGV
Mflv_2927|M.gilvum_PYR-GCK IASVIAERMDS-NGAADQLRTSGTD---------
MMAR_4848|M.marinum_M LDRLNDVAKDQAN-GQEPDTPKHP----------
MUL_0529|M.ulcerans_Agy99 LDQLHATEIQTPTTGQEPDEPNQPSSA-------
Mb3777|M.bovis_AF2122/97 L-------------GKDADQQT------------
MLBr_01600|M.leprae_Br4923 AHPRA-----------------------------
TH_0846|M.thermoresistible__bu AHPRA-----------------------------
MAB_3204c|M.abscessus_ATCC_199 AHPRA-----------------------------
Rv2659c|M.tuberculosis_H37Rv LSKLAENQEM------------------------
Mvan_4364|M.vanbaalenii_PYR-1 LSQLAVGES-------------------------
MSMEG_5754|M.smegmatis_MC2_155 LGSITTGKKKEAK---------------------