For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
SSGQPSKPQKHSVRTAEIADRAEATRAALIAAGRRLFVEKGYFATGTEEIVAAAGVGTRGALYHHFANKE ALFLAVFLAVQEQVDSQAPRPEYTEDALGALRAGLRAYLKSSLTGEVQRILMIEGPAVLGWQRWRELQVQ FGLGSIRALLEKAVEQGAVTPQPLDVLAHVLLAAADEAARFVANASDPQQARDDAIQVIDGILQRLGAAN *
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1931 | - | - | 100% (211) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_5253 | - | 4e-35 | 43.01% (193) | transcriptional regulator, TetR family protein |
| M. avium 104 | MAV_1141 | - | 7e-07 | 46.15% (52) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0080 | - | 1e-31 | 40.61% (197) | transcriptional regulatory protein |
| M. gilvum PYR-GCK | Mflv_4672 | - | 5e-08 | 28.65% (178) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0078 | - | 1e-31 | 40.61% (197) | transcriptional regulatory protein |
| M. leprae Br4923 | MLBr_02677 | - | 5e-18 | 34.32% (169) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2290 | - | 9e-17 | 26.24% (202) | transcriptional regulator TetR |
| M. marinum M | MMAR_0224 | - | 4e-34 | 42.64% (197) | transcriptional regulatory protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 1e-08 | 51.79% (56) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3094 | - | 1e-39 | 40.91% (198) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_4890 | - | 5e-34 | 42.64% (197) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4194 | - | 4e-08 | 48.21% (56) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0080|M.bovis_AF2122/97 ---------------------MEIKRRTQEERSAATREALITGARKLWGL
Rv0078|M.tuberculosis_H37Rv ---------------------MEIKRRTQEERSAATREALITGARKLWGL
MMAR_0224|M.marinum_M ---------------------MEIKRRTQEERSAATREALITAARKLWGS
MUL_4890|M.ulcerans_Agy99 ---------------------MESKRRTQEERSAATREALITAARKLWGS
MLBr_02677|M.leprae_Br4923 ---------------------MESQRRTQEERSTATRDALTLARHRLWRL
MAV_1931|M.avium_104 ----------MSSGQPSKPQKHSVRTAEIADRAEATRAALIAAGRRLFVE
TH_3094|M.thermoresistible__bu ----------MS--------KRGGRVEDRRARGDQTRRDLIDAGRALFVD
MSMEG_6807|M.smegmatis_MC2_155 ----------------------MVERWTRERRLEHTRSLLLDAAENVFSE
Mvan_4194|M.vanbaalenii_PYR-1 ----------------------MAERWTRERRLEHTRSVLLDAAEEVFAE
MAB_2290|M.abscessus_ATCC_1997 --------------------MSESKPGRRERYAALTRSAIVEAARMLFVE
Mflv_4672|M.gilvum_PYR-GCK MSELAKTAPRRGGQPANGTGSSGAARRGNRLPRDERRGQLLAAASEVFVD
* : . ::
Mb0080|M.bovis_AF2122/97 RGYAEVGTPEIATEAGV-TRGAMYHQFADKAALFRDVVEVVEQDVMARMA
Rv0078|M.tuberculosis_H37Rv RGYAEVGTPEIATEAGV-TRGAMYHQFADKAALFRDVVEVVEQDVMARMA
MMAR_0224|M.marinum_M RGYAEVGTPEIAAEAGV-TRGAMYHQFADKAALFGEVVEAVEQDVMTRMA
MUL_4890|M.ulcerans_Agy99 RGYAEVGTPEIAAEAGV-TRGAMYHQFADKAALFGEVVEAVEQDVMTRMA
MLBr_02677|M.leprae_Br4923 RGYAEVGTPEIAKEADT-TRGAVYHQFTDKAALFRDVVETVEQDAMAQIA
MAV_1931|M.avium_104 KGYFATGTEEIVAAAGVGTRGALYHHFANKEALFLAVFLAVQEQVDSQAP
TH_3094|M.thermoresistible__bu PGYFHTSVGDLVERSGVGTRGAFYHHFPDKAALFRAVFEDVEQDLTLRSI
MSMEG_6807|M.smegmatis_MC2_155 KGFTAATLDDIAFAAGY-TKGAIYKHFATKEDLFLAVSDRYWRRYFDNFA
Mvan_4194|M.vanbaalenii_PYR-1 KGFTPATLDDIARTAGY-TKGAIYKHFATKEDLFLAVSDRYWRRYFDNFA
MAB_2290|M.abscessus_ATCC_1997 RGFDDTSVDDIAEAAQV-SKGAIYHHFKDKQEIFIDVYRDATKGVIENVV
Mflv_4672|M.gilvum_PYR-GCK RGYHAAGMDEIADRAGV-SKPVLYQHFSSKVELYLAVLQRHVDNLVSGVR
*: . ::. : :: ..*::* * :: *
Mb0080|M.bovis_AF2122/97 TLVAASGAATPADAIRAAVDAWLEVSGD--PEVRQLVLLDAPVVLGWAGF
Rv0078|M.tuberculosis_H37Rv TLVAASGAATPADAIRAAVDAWLEVSGD--PEVRQLILLDAPVVLGWAGF
MMAR_0224|M.marinum_M TSVAASGAATPADAIRAAVDAWLEVSGD--PEVRQLILLDAPAVLGWAGF
MUL_4890|M.ulcerans_Agy99 TSVTTSGAATPADAIRAAVDAWLEVSGD--PEVRQLILLDAPAVLGWAGF
MLBr_02677|M.leprae_Br4923 SVVASSGAKTPVDAIRAKVDAWLEGLAD--PQVRQLILLYAPSVLGWAAF
MAV_1931|M.avium_104 R-PEYTEDA--LGALRAGLRAYLKSSLT--GEVQRILMIEGPAVLGWQRW
TH_3094|M.thermoresistible__bu ASPPEGSDS--WERLTRGLHGFLDAAAE--PEVQRIILIDGPVVLGWQTL
MSMEG_6807|M.smegmatis_MC2_155 EVMASAASVG-ARELDEIAKRWRQLSVDRGAEQAALGLEFTLYLKRNPEA
Mvan_4194|M.vanbaalenii_PYR-1 EVMASASRVG-AHELDEIAERWRQLSIDRGADHAALGLEFTLYLLRNPDA
MAB_2290|M.abscessus_ATCC_1997 KVLIDVPAGS-WNRIEAAASAVIKGYTD--NREPRVLVRQVMGVLGAERT
Mflv_4672|M.gilvum_PYR-GCK QALRTTTDNR--QRVRAAVQAFFDFIEH---DSQGYRLIFENDYVTEPQV
: . :
Mb0080|M.bovis_AF2122/97 RDVAQRYSLGMTEQ----LITEAIRAGQLARQPVRPLAQVLIGALDEAAM
Rv0078|M.tuberculosis_H37Rv RDVAQRYSLGMTEQ----LITEAIRAGQLARQPVRPLAQVLIGALDEAAM
MMAR_0224|M.marinum_M RDVAQRYSLGMTEQ----LITEAIRAGQLDRHPVRPLAHVLIGALDEAAM
MUL_4890|M.ulcerans_Agy99 CDVAQRYSLGMTEQ----LITEAIRAGQLDRHPVRPLAHVLIGALDEAAM
MLBr_02677|M.leprae_Br4923 RDVAQHYSLGMTEQQ---LLSEASRARQLA----QPLDHVLIGKLYESAM
MAV_1931|M.avium_104 RELQVQFGLGSIRA----LLEKAVEQGAVTPQPLDVLAHVLLAAADEAAR
TH_3094|M.thermoresistible__bu RSIEERSSLAMIQQ----ILRRAIADGSIEEQPVTALTHMLVSAVEEASL
MSMEG_6807|M.smegmatis_MC2_155 RDRVAAKRSEVVAQLTAFIVASIEKLGATLLISPETFAHALVATSDSVVL
Mvan_4194|M.vanbaalenii_PYR-1 RERVAAKRAEVVDQLAKFINEGMTRLGASLLISPLTFAQALVATSDSVVL
MAB_2290|M.abscessus_ATCC_1997 QALEGELALPLIRT----LLTEAEENGELRDLSIEKASQLIFRVLCESSL
Mflv_4672|M.gilvum_PYR-GCK AAQVKVATESCTDA----VFDLISHDSGLEPHRARMIAVGLVSISVDSAR
: :. .
Mb0080|M.bovis_AF2122/97 FIATAD-----DPKR------------ARRETRQVLRRLIDG--------
Rv0078|M.tuberculosis_H37Rv FIATAD-----DPKR------------ARRETRQVLRRLIDG--------
MMAR_0224|M.marinum_M FIATAD-----DPKR------------ARRESRQVLRRLIDG--------
MUL_4890|M.ulcerans_Agy99 FIATAD-----DPKR------------ARRESRQVLRRLIDG--------
MLBr_02677|M.leprae_Br4923 AIRRHHRLPEASPARNQTGAAPTHREHVARPSCEALTRHIRHRSTRTRSH
MAV_1931|M.avium_104 FVANAS-----DPQQ------------ARDDAIQVIDGILQR--------
TH_3094|M.thermoresistible__bu LIAHST-----DPER------------ARSDAEAVLDTLLNA--------
MSMEG_6807|M.smegmatis_MC2_155 SSELDN----VDLYR------------PMVEMYASMIKLPT---------
Mvan_4194|M.vanbaalenii_PYR-1 ASQLDD----IDLYR------------PVVEMYTSVIKLPD---------
MAB_2290|M.abscessus_ATCC_1997 LIANSA-----DYAE------------AAQEVETVMLCMFAG--------
Mflv_4672|M.gilvum_PYR-GCK YWLNNE-----RPID------------KDDAVEGTVQFIWGG--------
:
Mb0080|M.bovis_AF2122/97 ------MLNG-----------
Rv0078|M.tuberculosis_H37Rv ------MLNG-----------
MMAR_0224|M.marinum_M ------MLND-----------
MUL_4890|M.ulcerans_Agy99 ------MLND-----------
MLBr_02677|M.leprae_Br4923 RGKRGELLPRAATSSLL----
MAV_1931|M.avium_104 -------LGAAN---------
TH_3094|M.thermoresistible__bu -------LTRRRSRSR-----
MSMEG_6807|M.smegmatis_MC2_155 ---------------------
Mvan_4194|M.vanbaalenii_PYR-1 ---------------------
MAB_2290|M.abscessus_ATCC_1997 -------LRKPPAATRGRRKS
Mflv_4672|M.gilvum_PYR-GCK -------LSHVPLTRS-----