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TALGIGPDARRRLSAPRIAEIVADELRRQIISGELADGDLLPRQEVLVEQFNVSLVSLREALRILETEGL VSVRRGNRGGAVVHAPAKTSAAYMLGLLLQSESVAVADLGMALQELEPACAALAARRPDRADTLVPELTK INESMATHLDDGRLFTEIGRQFHDLVVRGCGNHTIIAVVGSLETLWTSHERQWADESSSRGTYPSLAQRR AVLNTHVKLTETIAEGNVDRARRIAGRHLADTQTYVLSGQPDQRIHAFSPQALARPRDLRRS*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1634 | - | - | 100% (273) | transcriptional regulator, GntR family protein |
| M. avium 104 | MAV_2560 | - | 6e-28 | 35.02% (237) | regulatory protein GntR, HTH |
| M. avium 104 | MAV_2542 | - | 2e-27 | 33.20% (241) | regulatory protein GntR, HTH |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3086c | - | 3e-13 | 27.51% (229) | GntR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4358 | - | 5e-46 | 40.51% (237) | regulatory protein GntR, HTH |
| M. tuberculosis H37Rv | Rv3060c | - | 3e-13 | 27.51% (229) | GntR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01188 | - | 5e-32 | 75.58% (86) | hypothetical protein MLBr_01188 |
| M. abscessus ATCC 19977 | MAB_4644c | - | 3e-12 | 32.92% (161) | GntR family transcriptional regulator |
| M. marinum M | MMAR_3975 | - | 1e-138 | 89.71% (272) | FadR family transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_5201 | - | 4e-28 | 34.66% (251) | regulatory protein GntR, HTH |
| M. thermoresistible (build 8) | TH_4024 | - | 2e-55 | 45.16% (248) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3832 | - | 1e-138 | 89.34% (272) | FadR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1986 | - | 3e-49 | 41.13% (248) | regulatory protein GntR, HTH |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_3975|M.marinum_M --------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MUL_3832|M.ulcerans_Agy99 --------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MAV_1634|M.avium_104 --------MTALGIGPDARRRLSAPRIAEIVADELRRQIISGELADGDLL
MLBr_01188|M.leprae_Br4923 -------------------------------------------------M
Mflv_4358|M.gilvum_PYR-GCK ------------------------------MASRLRDDILTGRLKEGDVL
Mvan_1986|M.vanbaalenii_PYR-1 ----------------MPAQRIRQPRVAELVASRLRDDILTGRLKEGDVL
TH_4024|M.thermoresistible__bu -----------------MVRRVRAPRVAEVVASAIRDDILSGRLTEGDVL
Mb3086c|M.bovis_AF2122/97 --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
Rv3060c|M.tuberculosis_H37Rv --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
MSMEG_5201|M.smegmatis_MC2_155 MAGSTPLAPMIGPDAITPRAAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
MAB_4644c|M.abscessus_ATCC_199 -----------------MHPRLSSQSLAEQVANILAAQIGDGRWSTGAKL
:
MMAR_3975|M.marinum_M PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKTSA
MUL_3832|M.ulcerans_Agy99 PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKASA
MAV_1634|M.avium_104 PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKTSA
MLBr_01188|M.leprae_Br4923 PRQEALVEPLNVSLLSFREALQIMDTERLISLRRGNRGSVVVHTPTRTSA
Mflv_4358|M.gilvum_PYR-GCK PSQESLFAEFGVSPPAVREAIHILEADGLISVRRGNVGGAVVHLPSAERT
Mvan_1986|M.vanbaalenii_PYR-1 PSQEALFAEFGVSPPAVREAVHILESDGLISVRRGNIGGAVVHLPSAERT
TH_4024|M.thermoresistible__bu PTQEHLFTEFGVSPPALREAIRILETEGLVSVRRGNVGGAVVHLPSARRT
Mb3086c|M.bovis_AF2122/97 GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
Rv3060c|M.tuberculosis_H37Rv GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
MSMEG_5201|M.smegmatis_MC2_155 PNEAELMSHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
MAB_4644c|M.abscessus_ATCC_199 PGEVALCEEFGVSRATVREAIRDLKTKGLVSTRQG----AGVFVTSDRPL
: * : ** .***:: :. . : *:* : .
MMAR_3975|M.marinum_M AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDR-----------
MUL_3832|M.ulcerans_Agy99 AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDR-----------
MAV_1634|M.avium_104 AYMLGLLLQSESVAVADLGMALQELEPACAALAARRPDR-----------
MLBr_01188|M.leprae_Br4923 AYMLGLLLQSKSIALADLGAALQELEPACAALAAQ---------------
Mflv_4358|M.gilvum_PYR-GCK AQMISMVLQTRAATPGDVSEALLHLEPICAGMCASREDR-----------
Mvan_1986|M.vanbaalenii_PYR-1 AQMISMVLQTRSATPADVSEALLHLEPICAGMCASRGDR-----------
TH_4024|M.thermoresistible__bu AQMIAMVLQSRSATPADVSEALLHLEPICAGMCAARPDR-----------
Mb3086c|M.bovis_AF2122/97 TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLR
Rv3060c|M.tuberculosis_H37Rv TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHIDEPGIERLRAVLR
MSMEG_5201|M.smegmatis_MC2_155 ARPVGLLLELSGADIADLLVARSAIEPMAARLLAENGTE-----------
MAB_4644c|M.abscessus_ATCC_199 GQWDRVLA---AAEIDAVVEIRRLLEVQAAGLAAERRNR-----------
: . : :* .* : *
MMAR_3975|M.marinum_M -ADTLVPELKRVNEAMSEHLDDGAM------FTEIGRQFHDLIVRGCGNH
MUL_3832|M.ulcerans_Agy99 -ADTLVPELKRVNEAMSEHLDDGAM------FTEIGRQFHDLIVRGCGNH
MAV_1634|M.avium_104 -ADTLVPELTKINESMATHLDDGRL------FTEIGRQFHDLVVRGCGNH
MLBr_01188|M.leprae_Br4923 --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK -ATEVVPHLQAAIDAQVEQFDSPSQ------YVPNARRFHEAIVSHCGNE
Mvan_1986|M.vanbaalenii_PYR-1 -MTEVVPHLQAAIDVQVEQFDRTSR------YVSNARRFHEAIVSRCGNE
TH_4024|M.thermoresistible__bu -MSEVVPYLQDEIDLQSTSFADTAR------FVSNARRFHEMLVARCGNE
Mb3086c|M.bovis_AF2122/97 AEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQ
Rv3060c|M.tuberculosis_H37Rv AEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQKSGTQ
MSMEG_5201|M.smegmatis_MC2_155 ---EQFAELDRMLEEHIPSDWQSDR------LAETTGDFHRRVVELSGNA
MAB_4644c|M.abscessus_ATCC_199 ---SDVAAIRRALVARAKAESAGDD----IEYVDADLEFHRAVVAAVHNP
MMAR_3975|M.marinum_M TIIAVVGSLETLWTSHEQ-QWADESAARGTYPSLTKRRAVLNT------H
MUL_3832|M.ulcerans_Agy99 TIIAVVGSLETLWTSHEQ-QWADESAARGTYPSLAKRRAVLNA------H
MAV_1634|M.avium_104 TIIAVVGSLETLWTSHER-QWADESSSRGTYPSLAQRRAVLNT------H
MLBr_01188|M.leprae_Br4923 --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK PMILLIGSLQVIWSAHESSVWSDEYHPSDPMEPKTMR-AALRD------H
Mvan_1986|M.vanbaalenii_PYR-1 PMILLIGSLELIWSAHESSVWSDECHPEDPMRPKTMR-AALRD------H
TH_4024|M.thermoresistible__bu PMILLIGALELIWSAHEAGVWSDDSPGGGRPEAATMR-AALRD------H
Mb3086c|M.bovis_AF2122/97 SAGEAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQHQ
Rv3060c|M.tuberculosis_H37Rv SAGEAVEAAGQVHNEHSDIVAAVTAGDSAWAKTLSERHVEAVAGWLQQHQ
MSMEG_5201|M.smegmatis_MC2_155 TLGIIAGMLHEITVRHHQFLFREHRPVSKSDYDKLMR-----------SY
MAB_4644c|M.abscessus_ATCC_199 LLDELFDSFSVRMREAMLALLAGSAERPHDQEH----------------H
MMAR_3975|M.marinum_M IKLTETIAEGDVDRARRIAGRHLADTQTYVLSGRAEQRIYALSPQALSRP
MUL_3832|M.ulcerans_Agy99 IKLTETIAEGDVDRARRIAGRHLADTQTYVLSGRAEQRIYALSPQALSRP
MAV_1634|M.avium_104 VKLTETIAEGNVDRARRIAGRHLADTQTYVLSGQPDQRIHAFSPQALARP
MLBr_01188|M.leprae_Br4923 --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK QRLLDAIAEGNSARAVKLAGDHLAAARRNTLAAASQKTIEAKLISN----
Mvan_1986|M.vanbaalenii_PYR-1 HRIVEAIIDGNSSRAVRLAEDHLAAARHNTLAAGSDRTIEAKLIANHDR-
TH_4024|M.thermoresistible__bu RRILDAVIDGDSARAVRLAQKHLAAARRHTLACGADTTIEAKLVSRPDH-
Mb3086c|M.bovis_AF2122/97 RGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQV
Rv3060c|M.tuberculosis_H37Rv RGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIGDDIAASGWQV
MSMEG_5201|M.smegmatis_MC2_155 RKLMQIMRSGDGDAAEAHWRTHLDTARALMLQGLESVKVRDVMG------
MAB_4644c|M.abscessus_ATCC_199 QWLFDAIVDGSTRRAVELATDQLQHVRMR---------------------
MMAR_3975|M.marinum_M RDMRRP--------------------------------------------
MUL_3832|M.ulcerans_Agy99 RDMRRP--------------------------------------------
MAV_1634|M.avium_104 RDLRRS--------------------------------------------
MLBr_01188|M.leprae_Br4923 --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4024|M.thermoresistible__bu --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 GSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQ
Rv3060c|M.tuberculosis_H37Rv GSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGPGGGLVVTTPQ
MSMEG_5201|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4644c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3975|M.marinum_M --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
MAV_1634|M.avium_104 --------------------------------------------------
MLBr_01188|M.leprae_Br4923 --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4024|M.thermoresistible__bu --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 PQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASFL
Rv3060c|M.tuberculosis_H37Rv PQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKRRSEPEVASFL
MSMEG_5201|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4644c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3975|M.marinum_M --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
MAV_1634|M.avium_104 --------------------------------------------------
MLBr_01188|M.leprae_Br4923 --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4024|M.thermoresistible__bu --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 DTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFR
Rv3060c|M.tuberculosis_H37Rv DTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDLFLLILVELFR
MSMEG_5201|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4644c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3975|M.marinum_M --------------------------------------------------
MUL_3832|M.ulcerans_Agy99 --------------------------------------------------
MAV_1634|M.avium_104 --------------------------------------------------
MLBr_01188|M.leprae_Br4923 --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1 --------------------------------------------------
TH_4024|M.thermoresistible__bu --------------------------------------------------
Mb3086c|M.bovis_AF2122/97 RHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAA
Rv3060c|M.tuberculosis_H37Rv RHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARCRTRRHLDAAA
MSMEG_5201|M.smegmatis_MC2_155 --------------------------------------------------
MAB_4644c|M.abscessus_ATCC_199 --------------------------------------------------
MMAR_3975|M.marinum_M ----
MUL_3832|M.ulcerans_Agy99 ----
MAV_1634|M.avium_104 ----
MLBr_01188|M.leprae_Br4923 ----
Mflv_4358|M.gilvum_PYR-GCK ----
Mvan_1986|M.vanbaalenii_PYR-1 ----
TH_4024|M.thermoresistible__bu ----
Mb3086c|M.bovis_AF2122/97 SWWL
Rv3060c|M.tuberculosis_H37Rv SWWL
MSMEG_5201|M.smegmatis_MC2_155 ----
MAB_4644c|M.abscessus_ATCC_199 ----