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M. leprae Br4923 MLBr_01188 (-)

annotation: hypothetical protein MLBr_01188
coordinates: 1390623 - 1390883
length: 86

PRQEALVEPLNVSLLSFREALQIMDTERLISLRRGNRGSVVVHTPTRTSAAYMLGLLLQSKSIALADLGA
ALQELEPACAALAAQ*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. leprae Br4923MLBr_01188--100% (86)hypothetical protein MLBr_01188

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3086c-3e-0529.07% (86) GntR family transcriptional regulator
M. gilvum PYR-GCKMflv_4358-1e-1442.35% (85) regulatory protein GntR, HTH
M. tuberculosis H37RvRv3060c-3e-0529.07% (86) GntR family transcriptional regulator
M. abscessus ATCC 19977-----
M. marinum MMMAR_3975-6e-3376.74% (86) FadR family transcriptional regulator
M. avium 104MAV_1634-3e-3275.58% (86) transcriptional regulator, GntR family protein
M. smegmatis MC2 155MSMEG_5201-5e-1036.05% (86) regulatory protein GntR, HTH
M. thermoresistible (build 8)TH_4024-1e-1647.06% (85) PUTATIVE transcriptional regulator, GntR family
M. ulcerans Agy99MUL_3832-2e-3275.58% (86) FadR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_1986-9e-1645.88% (85) regulatory protein GntR, HTH

CLUSTAL 2.0.9 multiple sequence alignment


MMAR_3975|M.marinum_M               --------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MUL_3832|M.ulcerans_Agy99           --------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MAV_1634|M.avium_104                --------MTALGIGPDARRRLSAPRIAEIVADELRRQIISGELADGDLL
MLBr_01188|M.leprae_Br4923          -------------------------------------------------M
Mflv_4358|M.gilvum_PYR-GCK          ------------------------------MASRLRDDILTGRLKEGDVL
Mvan_1986|M.vanbaalenii_PYR-1       ----------------MPAQRIRQPRVAELVASRLRDDILTGRLKEGDVL
TH_4024|M.thermoresistible__bu      -----------------MVRRVRAPRVAEVVASAIRDDILSGRLTEGDVL
MSMEG_5201|M.smegmatis_MC2_155      MAGSTPLAPMIGPDAITPRAAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
Mb3086c|M.bovis_AF2122/97           --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
Rv3060c|M.tuberculosis_H37Rv        --------------MSTEPDAVWTDKRASKIARRIEADIVRRGWPIGASL
                                                                                     :

MMAR_3975|M.marinum_M               PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKTSA
MUL_3832|M.ulcerans_Agy99           PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKASA
MAV_1634|M.avium_104                PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKTSA
MLBr_01188|M.leprae_Br4923          PRQEALVEPLNVSLLSFREALQIMDTERLISLRRGNRGSVVVHTPTRTSA
Mflv_4358|M.gilvum_PYR-GCK          PSQESLFAEFGVSPPAVREAIHILEADGLISVRRGNVGGAVVHLPSAERT
Mvan_1986|M.vanbaalenii_PYR-1       PSQEALFAEFGVSPPAVREAVHILESDGLISVRRGNIGGAVVHLPSAERT
TH_4024|M.thermoresistible__bu      PTQEHLFTEFGVSPPALREAIRILETEGLVSVRRGNVGGAVVHLPSARRT
MSMEG_5201|M.smegmatis_MC2_155      PNEAELMSHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
Mb3086c|M.bovis_AF2122/97           GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
Rv3060c|M.tuberculosis_H37Rv        GSESALQQRFCVSRSVLREAVRLVEHHQVARMRRGPNGGLFICEPNAGPA
                                      :  *   : **   .***::::: . :  :***   .  :  *    .

MMAR_3975|M.marinum_M               AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPELKRV
MUL_3832|M.ulcerans_Agy99           AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPELKRV
MAV_1634|M.avium_104                AYMLGLLLQSESVAVADLGMALQELEPACAALAARRPDRADTLVPELTKI
MLBr_01188|M.leprae_Br4923          AYMLGLLLQSKSIALADLGAALQELEPACAALAAQ---------------
Mflv_4358|M.gilvum_PYR-GCK          AQMISMVLQTRAATPGDVSEALLHLEPICAGMCASREDRATEVVPHLQAA
Mvan_1986|M.vanbaalenii_PYR-1       AQMISMVLQTRSATPADVSEALLHLEPICAGMCASRGDRMTEVVPHLQAA
TH_4024|M.thermoresistible__bu      AQMIAMVLQSRSATPADVSEALLHLEPICAGMCAARPDRMSEVVPYLQDE
MSMEG_5201|M.smegmatis_MC2_155      ARPVGLLLELSGADIADLLVARSAIEPMAARLLAENG--TEEQFAELDRM
Mb3086c|M.bovis_AF2122/97           TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHID-----EPGIERL
Rv3060c|M.tuberculosis_H37Rv        TRAVVIYLEYLGTTIGDLLGARLVLEPLAASLAAEHID-----EPGIERL
                                    :  : : *:  .   .*:  *   :** .* : *                

MMAR_3975|M.marinum_M               NEAMSEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSHEQ
MUL_3832|M.ulcerans_Agy99           NEAMSEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSHEQ
MAV_1634|M.avium_104                NESMATHLDDGRLFTEIGRQFHDLVVRGCGNHTIIAVVGSLETLWTSHER
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK          IDAQVEQFDSPSQYVPNARRFHEAIVSHCGNEPMILLIGSLQVIWSAHES
Mvan_1986|M.vanbaalenii_PYR-1       IDVQVEQFDRTSRYVSNARRFHEAIVSRCGNEPMILLIGSLELIWSAHES
TH_4024|M.thermoresistible__bu      IDLQSTSFADTARFVSNARRFHEMLVARCGNEPMILLIGALELIWSAHEA
MSMEG_5201|M.smegmatis_MC2_155      LEEHIPSDWQSDRLAETTGDFHRRVVELSGNATLGIIAGMLHEITVRHHQ
Mb3086c|M.bovis_AF2122/97           RAVLRAEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQ
Rv3060c|M.tuberculosis_H37Rv        RAVLRAEERWRPGLPPPPEQFYRVLAEQSKNPVLQLFIDILMRLTKRYVQ
                                                                                      

MMAR_3975|M.marinum_M               -QWADESAARGTYPSLTKRRAVLNTHIKLTETIAEGDVDRARRIAGRHLA
MUL_3832|M.ulcerans_Agy99           -QWADESAARGTYPSLAKRRAVLNAHIKLTETIAEGDVDRARRIAGRHLA
MAV_1634|M.avium_104                -QWADESSSRGTYPSLAQRRAVLNTHVKLTETIAEGNVDRARRIAGRHLA
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK          SVWSDEYHPSDPMEPKTMR-AALRDHQRLLDAIAEGNSARAVKLAGDHLA
Mvan_1986|M.vanbaalenii_PYR-1       SVWSDECHPEDPMRPKTMR-AALRDHHRIVEAIIDGNSSRAVRLAEDHLA
TH_4024|M.thermoresistible__bu      GVWSDDSPGGGRPEAATMR-AALRDHRRILDAVIDGDSARAVRLAQKHLA
MSMEG_5201|M.smegmatis_MC2_155      FLFREHRPVSKSDYDKLMR-----SYRKLMQIMRSGDGDAAEAHWRTHLD
Mb3086c|M.bovis_AF2122/97           KSGTQSAGEAVEAAGQVHN-----EHSDIVAAVTAGDSAWAKTLSERHVE
Rv3060c|M.tuberculosis_H37Rv        KSGTQSAGEAVEAAGQVHN-----EHSDIVAAVTAGDSAWAKTLSERHVE
                                                                                      

MMAR_3975|M.marinum_M               DTQTYVLSGRAEQRIYALSPQALSRPRDMRRP------------------
MUL_3832|M.ulcerans_Agy99           DTQTYVLSGRAEQRIYALSPQALSRPRDMRRP------------------
MAV_1634|M.avium_104                DTQTYVLSGQPDQRIHAFSPQALARPRDLRRS------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK          AARRNTLAAASQKTIEAKLISN----------------------------
Mvan_1986|M.vanbaalenii_PYR-1       AARHNTLAAGSDRTIEAKLIANHDR-------------------------
TH_4024|M.thermoresistible__bu      AARRHTLACGADTTIEAKLVSRPDH-------------------------
MSMEG_5201|M.smegmatis_MC2_155      TARALMLQGLESVKVRDVMG------------------------------
Mb3086c|M.bovis_AF2122/97           AVAGWLQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIG
Rv3060c|M.tuberculosis_H37Rv        AVAGWLQQHQRGNDAAVRNGGRAREPRRAQQLILGAPRGKLAEVLAATIG
                                                                                      

MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MAV_1634|M.avium_104                --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4024|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           DDIAASGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGP
Rv3060c|M.tuberculosis_H37Rv        DDIAASGWQVGSVFGTETALLERYQVSRAVLREAVRLLEYHAIAHMRRGP
                                                                                      

MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MAV_1634|M.avium_104                --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4024|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           GGGLVVTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKR
Rv3060c|M.tuberculosis_H37Rv        GGGLVVTTPQPQASIDTIALYLQYRKPSREDLRCVRDAIEIDNVAKVVKR
                                                                                      

MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MAV_1634|M.avium_104                --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4024|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           RSEPEVASFLDTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDL
Rv3060c|M.tuberculosis_H37Rv        RSEPEVASFLDTLGRPRLDNPTDDVRAAAVEEFRFHVGLARAAGNTMLDL
                                                                                      

MMAR_3975|M.marinum_M               --------------------------------------------------
MUL_3832|M.ulcerans_Agy99           --------------------------------------------------
MAV_1634|M.avium_104                --------------------------------------------------
MLBr_01188|M.leprae_Br4923          --------------------------------------------------
Mflv_4358|M.gilvum_PYR-GCK          --------------------------------------------------
Mvan_1986|M.vanbaalenii_PYR-1       --------------------------------------------------
TH_4024|M.thermoresistible__bu      --------------------------------------------------
MSMEG_5201|M.smegmatis_MC2_155      --------------------------------------------------
Mb3086c|M.bovis_AF2122/97           FLLILVELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARC
Rv3060c|M.tuberculosis_H37Rv        FLLILVELFRRHLSSTEQALPTWSDVVAVGHAHVRILEAIGSGDDSLARC
                                                                                      

MMAR_3975|M.marinum_M               --------------
MUL_3832|M.ulcerans_Agy99           --------------
MAV_1634|M.avium_104                --------------
MLBr_01188|M.leprae_Br4923          --------------
Mflv_4358|M.gilvum_PYR-GCK          --------------
Mvan_1986|M.vanbaalenii_PYR-1       --------------
TH_4024|M.thermoresistible__bu      --------------
MSMEG_5201|M.smegmatis_MC2_155      --------------
Mb3086c|M.bovis_AF2122/97           RTRRHLDAAASWWL
Rv3060c|M.tuberculosis_H37Rv        RTRRHLDAAASWWL