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ASRLRDDILTGRLKEGDVLPSQESLFAEFGVSPPAVREAIHILEADGLISVRRGNVGGAVVHLPSAERTA QMISMVLQTRAATPGDVSEALLHLEPICAGMCASREDRATEVVPHLQAAIDAQVEQFDSPSQYVPNARRF HEAIVSHCGNEPMILLIGSLQVIWSAHESSVWSDEYHPSDPMEPKTMRAALRDHQRLLDAIAEGNSARAV KLAGDHLAAARRNTLAAASQKTIEAKLISN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4358 | - | - | 100% (241) | regulatory protein GntR, HTH |
| M. gilvum PYR-GCK | Mflv_2114 | - | 2e-22 | 29.96% (227) | GntR domain-containing protein |
| M. gilvum PYR-GCK | Mflv_0016 | - | 3e-08 | 27.66% (235) | GntR domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0601 | - | 7e-12 | 27.23% (235) | GntR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0586 | - | 7e-12 | 27.23% (235) | GntR family transcriptional regulator |
| M. leprae Br4923 | MLBr_01188 | - | 2e-14 | 42.35% (85) | hypothetical protein MLBr_01188 |
| M. abscessus ATCC 19977 | MAB_4644c | - | 3e-14 | 32.29% (223) | GntR family transcriptional regulator |
| M. marinum M | MMAR_3975 | - | 9e-48 | 41.77% (237) | FadR family transcriptional regulator |
| M. avium 104 | MAV_1634 | - | 4e-46 | 40.51% (237) | transcriptional regulator, GntR family protein |
| M. smegmatis MC2 155 | MSMEG_5201 | - | 2e-21 | 27.93% (222) | regulatory protein GntR, HTH |
| M. thermoresistible (build 8) | TH_4024 | - | 9e-95 | 70.83% (240) | PUTATIVE transcriptional regulator, GntR family |
| M. ulcerans Agy99 | MUL_3832 | - | 2e-47 | 42.02% (238) | FadR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1986 | - | 1e-117 | 86.31% (241) | regulatory protein GntR, HTH |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4358|M.gilvum_PYR-GCK ------------------------------MASRLRDDILTGRLKEGDVL
Mvan_1986|M.vanbaalenii_PYR-1 ----------------MPAQRIRQPRVAELVASRLRDDILTGRLKEGDVL
TH_4024|M.thermoresistible__bu -----------------MVRRVRAPRVAEVVASAIRDDILSGRLTEGDVL
MMAR_3975|M.marinum_M --------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MUL_3832|M.ulcerans_Agy99 --------MTALGIGPDPRRRLSAPRIAEIVADELRRQIIDGELADGDLL
MAV_1634|M.avium_104 --------MTALGIGPDARRRLSAPRIAEIVADELRRQIISGELADGDLL
MLBr_01188|M.leprae_Br4923 -------------------------------------------------M
Mb0601|M.bovis_AF2122/97 ----------------MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEAL
Rv0586|M.tuberculosis_H37Rv ----------------MALQPVTRRSVPEEVFEQIATDVLTGEMPPGEAL
MSMEG_5201|M.smegmatis_MC2_155 MAGSTPLAPMIGPDAITPRAAVRSPKTAELVAGTLRRMVVEGQLKDGDFL
MAB_4644c|M.abscessus_ATCC_199 -----------------MHPRLSSQSLAEQVANILAAQIGDGRWSTGAKL
:
Mflv_4358|M.gilvum_PYR-GCK PSQESLFAEFGVSPPAVREAIHILEADGLISVRRGNVGGAVVHLPSAERT
Mvan_1986|M.vanbaalenii_PYR-1 PSQEALFAEFGVSPPAVREAVHILESDGLISVRRGNIGGAVVHLPSAERT
TH_4024|M.thermoresistible__bu PTQEHLFTEFGVSPPALREAIRILETEGLVSVRRGNVGGAVVHLPSARRT
MMAR_3975|M.marinum_M PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKTSA
MUL_3832|M.ulcerans_Agy99 PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKASA
MAV_1634|M.avium_104 PRQEVLVEQFNVSLVSLREALRILETEGLVSVRRGNRGGAVVHAPAKTSA
MLBr_01188|M.leprae_Br4923 PRQEALVEPLNVSLLSFREALQIMDTERLISLRRGNRGSVVVHTPTRTSA
Mb0601|M.bovis_AF2122/97 PSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVT-TVRDFRRHAGL
Rv0586|M.tuberculosis_H37Rv PSERRLAELLGVSRPAVREALKRLSAAGLVEVRQGDVT-TVRDFRRHAGL
MSMEG_5201|M.smegmatis_MC2_155 PNEAELMSHFGVSRPTLREAVRVLESERLVEVRRGSRTGARVRVPGPEIV
MAB_4644c|M.abscessus_ATCC_199 PGEVALCEEFGVSRATVREAIRDLKTKGLVSTRQGAGVFVTSDRPLGQWD
* : * :.** :.***:: :.: *:. *:* .
Mflv_4358|M.gilvum_PYR-GCK AQMISMVLQTRAATPGDVSEALLHLEPICAGMCASREDRATEVVPHLQAA
Mvan_1986|M.vanbaalenii_PYR-1 AQMISMVLQTRSATPADVSEALLHLEPICAGMCASRGDRMTEVVPHLQAA
TH_4024|M.thermoresistible__bu AQMIAMVLQSRSATPADVSEALLHLEPICAGMCAARPDRMSEVVPYLQDE
MMAR_3975|M.marinum_M AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPELKRV
MUL_3832|M.ulcerans_Agy99 AYMLGLLLQSESVAVSDLGAALQELEPACAALAAQRPDRADTLVPELKRV
MAV_1634|M.avium_104 AYMLGLLLQSESVAVADLGMALQELEPACAALAARRPDRADTLVPELTKI
MLBr_01188|M.leprae_Br4923 AYMLGLLLQSKSIALADLGAALQELEPACAALAAQ---------------
Mb0601|M.bovis_AF2122/97 DLLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQD
Rv0586|M.tuberculosis_H37Rv DLLPRLLFRNGELDISVVRSILEARLRNFPKVAELAAERNEPELAELLQD
MSMEG_5201|M.smegmatis_MC2_155 ARPVGLLLELSGADIADLLVARSAIEPMAARLLAENG--TEEQFAELDRM
MAB_4644c|M.abscessus_ATCC_199 RVLA-------AAEIDAVVEIRRLLEVQAAGLAAERRNRSDVAAIRRALV
: . :
Mflv_4358|M.gilvum_PYR-GCK IDAQVEQFDSPSQYVPNARRFHEAIVSHCGNEPMILLIGSLQVIWSAHES
Mvan_1986|M.vanbaalenii_PYR-1 IDVQVEQFDRTSRYVSNARRFHEAIVSRCGNEPMILLIGSLELIWSAHES
TH_4024|M.thermoresistible__bu IDLQSTSFADTARFVSNARRFHEMLVARCGNEPMILLIGALELIWSAHEA
MMAR_3975|M.marinum_M NEAMSEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSHEQ
MUL_3832|M.ulcerans_Agy99 NEAMSEHLDDGAMFTEIGRQFHDLIVRGCGNHTIIAVVGSLETLWTSHEQ
MAV_1634|M.avium_104 NESMATHLDDGRLFTEIGRQFHDLVVRGCGNHTIIAVVGSLETLWTSHER
MLBr_01188|M.leprae_Br4923 --------------------------------------------------
Mb0601|M.bovis_AF2122/97 SLRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLA
Rv0586|M.tuberculosis_H37Rv SLRALDTEEDPIVWQRHTLDFWDHVVDSAGSIVDRLMYNAFRAAYEPTLA
MSMEG_5201|M.smegmatis_MC2_155 LEEHIPSDWQSDRLAETTGDFHRRVVELSGNATLGIIAGMLHEITVRHHQ
MAB_4644c|M.abscessus_ATCC_199 ARAKAESAGDDIEYVDADLEFHRAVVAAVHNPLLDELFDSFSVRMREAML
Mflv_4358|M.gilvum_PYR-GCK SVWSDEYHPSDPMEPKTMRAALRDHQRLLDAIAEGNSARAVKLAGDHLAA
Mvan_1986|M.vanbaalenii_PYR-1 SVWSDECHPEDPMRPKTMRAALRDHHRIVEAIIDGNSSRAVRLAEDHLAA
TH_4024|M.thermoresistible__bu GVWSDDSPGGGRPEAATMRAALRDHRRILDAVIDGDSARAVRLAQKHLAA
MMAR_3975|M.marinum_M QWADESAARGTYPSLTKRRAVLNTHIKLTETIAEGDVDRARRIAGRHLAD
MUL_3832|M.ulcerans_Agy99 QWADESAARGTYPSLAKRRAVLNAHIKLTETIAEGDVDRARRIAGRHLAD
MAV_1634|M.avium_104 QWADESSSRGTYPSLAQRRAVLNTHVKLTETIAEGNVDRARRIAGRHLAD
MLBr_01188|M.leprae_Br4923 --------------------------------------------------
Mb0601|M.bovis_AF2122/97 ALTTTMTAAAKRP---------SDYRKLADAICSGDPTGAKKAAQDLLEL
Rv0586|M.tuberculosis_H37Rv ALTTTMTAAAKRP---------SDYRKLADAICSGDPTGAKKAAQDLLEL
MSMEG_5201|M.smegmatis_MC2_155 FLFREHRPVSKSD----YDKLMRSYRKLMQIMRSGDGDAAEAHWRTHLDT
MAB_4644c|M.abscessus_ATCC_199 ALLAGSAERPHDQ---------EHHQWLFDAIVDGSTRRAVELATDQLQH
Mflv_4358|M.gilvum_PYR-GCK ARRNTLAAASQKTIEAKLISN----------
Mvan_1986|M.vanbaalenii_PYR-1 ARHNTLAAGSDRTIEAKLIANHDR-------
TH_4024|M.thermoresistible__bu ARRHTLACGADTTIEAKLVSRPDH-------
MMAR_3975|M.marinum_M TQTYVLSGRAEQRIYALSPQALSRPRDMRRP
MUL_3832|M.ulcerans_Agy99 TQTYVLSGRAEQRIYALSPQALSRPRDMRRP
MAV_1634|M.avium_104 TQTYVLSGQPDQRIHAFSPQALARPRDLRRS
MLBr_01188|M.leprae_Br4923 -------------------------------
Mb0601|M.bovis_AF2122/97 ANTSLMAVLVSQASRQ---------------
Rv0586|M.tuberculosis_H37Rv ANTSLMAVLVSQASRQ---------------
MSMEG_5201|M.smegmatis_MC2_155 ARALMLQGLESVKVRDVMG------------
MAB_4644c|M.abscessus_ATCC_199 VRMR---------------------------