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TDVRDHHPKRGELRIYLGAAPGVGKTYSMLGEAHRRLERGTDLVAGVVETHGRAKTAELLEGIEIIPPRY IEYRGGRFPELDVPAVLARHPQVVLVDELAHTNTPGSKNPKRWQDVEELLDAGITVISTVNVQHLESLND VVAQITGIEQKETVPDSVVRQASQVELIDITPEALRRRLSHGNVYAPDRIDAALSNYFRRGNLTALRELA LLWLADQVDTALAKYRAENKITDTWEARERVVVAVTGGPESETLVRRASRIASKSSAELMVVHVIRGDGL AGLSESRMAKIRELASSLDASLHTIVGDEVPAALLEFAREMNATQLVIGTSRRSRWARLFEEGIGPRIVE LSGKIDVHLVTHEESKRGFRASSLAPRERRVASWLAALIVPSVICAVTVTWLDPYLDTGGESALFFVGVL LVGLLGGIAPAALSAVLSGLLLNYYLIAPRHSFTIAEPNSAITELVLLLIAVAVAVLVDFAAKRTREARR ASQEAELLTLFAGSVLRGADLETLLERVRETYAQRSVSMLRESEDARAGGTKTQVVACVGRDPCVSVDAA DTAIEVGGPDSSEFQMLLAGRKLSARDRRVLSAVARQAAGLIRQRELAEEASRTEAIVRADELRRSLLSA VSHDLRTPLAAAKVAVSSLRAEDVAFSPTDTAELLATIEESIDQLTALVGNLLDSSRLAAGAIHPDLRRV YLEEAVQRALVSIGKGATGFFRSAIDRVKVDVGDAMVMADAGLLERVLANLIDNALRYAPNCVVRVNAGQ VGDRVLINVIDEGPGIPHGAEEQIFEAFQRLGDHDNTTGVGLGMSVARGFVEAMGGTITATDTPGGGLTV MVDMAAPQSEGAA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1170 | - | - | 100% (854) | sensor protein KdpD |
| M. avium 104 | MAV_3405 | - | 5e-21 | 31.28% (243) | hypothetical protein MAV_3405 |
| M. avium 104 | MAV_0703 | - | 5e-19 | 29.18% (305) | sensor histidine kinase PhoR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1056c | kdpD | 0.0 | 80.24% (840) | sensor protein KDPD |
| M. gilvum PYR-GCK | Mflv_0083 | - | 4e-22 | 27.49% (411) | histidine kinase |
| M. tuberculosis H37Rv | Rv1028c | kdpD | 0.0 | 80.24% (840) | sensor protein KDPD |
| M. leprae Br4923 | MLBr_02440 | - | 7e-19 | 27.54% (305) | putative two-component system sensor histidine kinase |
| M. abscessus ATCC 19977 | MAB_3251c | - | 0.0 | 61.52% (842) | sensor protein KdpD |
| M. marinum M | MMAR_0634 | kdpD | 0.0 | 76.48% (842) | two-component system response phosphate sensor kinase, KdpD |
| M. smegmatis MC2 155 | MSMEG_5395 | - | 0.0 | 76.06% (848) | sensor protein KdpD |
| M. thermoresistible (build 8) | TH_4550 | - | 1e-20 | 30.69% (290) | PUTATIVE putative integral membrane sensor signal transduction |
| M. ulcerans Agy99 | MUL_0464 | phoR | 3e-21 | 31.05% (277) | two component system response phosphate sensor kinase, PhoR |
| M. vanbaalenii PYR-1 | Mvan_4762 | - | 0.0 | 75.44% (847) | osmosensitive K+ channel signal transduction histidine kinase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_5395|M.smegmatis_MC2_155 -----------MTTRASNAS----KRGELRIYLGAAPGVGKTYAMLGEAH
Mvan_4762|M.vanbaalenii_PYR-1 -----------MDDESVAASPHKAKRGELRIYLGAAPGVGKTYAMLGEAH
Mb1056c|M.bovis_AF2122/97 MTLLFADLCAIFTPYRWMIEHVTTKRGQLRIYLGAAPGVGKTYAMLGEAH
Rv1028c|M.tuberculosis_H37Rv MTLLFADLCAIFTPYRWMIEHVTTKRGQLRIYLGAAPGVGKTYAMLGEAH
MMAR_0634|M.marinum_M -----------------MTPDYPRKRGELRIYLGAAPGVGKTFAMLGEAQ
MAV_1170|M.avium_104 ---------------MTDVRDHHPKRGELRIYLGAAPGVGKTYSMLGEAH
MAB_3251c|M.abscessus_ATCC_199 ------------------MPDGLRARGTLRIYLGAAPGVGKTFAMLNEAH
Mflv_0083|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02440|M.leprae_Br4923 --------------------------------------------------
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 RRLDRGTDLVAAVVETHGRKNTAELLAGIEVIPPRYIEYRGGRFPELDVP
Mvan_4762|M.vanbaalenii_PYR-1 RRLERGTDVVAAVVETHGRKKTAELFEGIEIVPPKLIAYRGSDFAELDVE
Mb1056c|M.bovis_AF2122/97 RRLERGTDVVAAVVETHGRNKTAKLLEGIEMIPPRYVEYRGARFPELDVE
Rv1028c|M.tuberculosis_H37Rv RRLERGTDVVAAVVETHGRNKTAKLLEGIEMIPPRYVEYRGARFPELDVE
MMAR_0634|M.marinum_M RRLERGTDVVAAVVETHGRKRTAELLEGIERIPPKFIEYRGSRFAELDVE
MAV_1170|M.avium_104 RRLERGTDLVAGVVETHGRAKTAELLEGIEIIPPRYIEYRGGRFPELDVP
MAB_3251c|M.abscessus_ATCC_199 RRAGRGTDVVAAVVETHGRSKTAELLDGLELIPPKEMVHRGTAMYELDVD
Mflv_0083|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02440|M.leprae_Br4923 --------------------------------------------------
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 AVLDRKPQVVLVDELAHTNTPGSKNAKRWQDVDELLNAGITVISTVNVQH
Mvan_4762|M.vanbaalenii_PYR-1 AVLRRNPQVVLVDELAHTNTPGSKNTKRWQDIEELLDAGITVITTVNVQH
Mb1056c|M.bovis_AF2122/97 AVLRRHPQVVLVDELAHTNTPGSKNPKRWQDVQEILDAGITVISTVNIQH
Rv1028c|M.tuberculosis_H37Rv AVLRRHPQVVLVDELAHTNTPGSKNPKRWQDVQEILDAGITVISTVNIQH
MMAR_0634|M.marinum_M AVLRRQPQVVLVDELAHTNTPGSKNPKRWQDVEELLDAGITVISTVNVQH
MAV_1170|M.avium_104 AVLARHPQVVLVDELAHTNTPGSKNPKRWQDVEELLDAGITVISTVNVQH
MAB_3251c|M.abscessus_ATCC_199 AVLERRPALVLIDEMAHTNVPGSRNPKRWQDIDEILDAGIDVLTTINVQH
Mflv_0083|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02440|M.leprae_Br4923 --------------------------------------------------
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 LDSLNDVVAAITGIEQQETVPDEVVRSADQIELVDITPEALRRRLSHGNV
Mvan_4762|M.vanbaalenii_PYR-1 LESLNDVVTQITGIEQQEKVPDEVVRAADQVELVDITPEALRRRLAHGNV
Mb1056c|M.bovis_AF2122/97 LEGLNDVVEQITGIEQKEKIPDEIVRAADQVELVDITPEALRRRLAHGNV
Rv1028c|M.tuberculosis_H37Rv LEGLNDVVEQITGIEQKEKIPDEIVRAADQVELVDITPEALRRRLAHGNV
MMAR_0634|M.marinum_M LESLNDVVAQITGIEQQEKVPDEIVRAAEQVELVDITPEALRRRLAHGNV
MAV_1170|M.avium_104 LESLNDVVAQITGIEQKETVPDSVVRQASQVELIDITPEALRRRLSHGNV
MAB_3251c|M.abscessus_ATCC_199 LESLNDVVEQITGIVQRETVPDAVVRRAEQVELVDITPEALRRRMVHGNV
Mflv_0083|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02440|M.leprae_Br4923 --------------------------------------------------
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 YAPERIDAALSNYFRRGNLTALRELALLWLADQVDAALAKYRADNKITAL
Mvan_4762|M.vanbaalenii_PYR-1 YAPERVDAALSNYFRRGNLTALRELALLWLADQVDSALEKYRADNKITDT
Mb1056c|M.bovis_AF2122/97 YAAERVDAALSNYFRTGNLTALREIALLWLADQVDAALEKYRADKKITAT
Rv1028c|M.tuberculosis_H37Rv YAAERVDAALSNYFRTGNLTALREIALLWLADQVDAALEKYRADKKITAT
MMAR_0634|M.marinum_M YAAERVDAALANYFRTGNLTALRELALLWLADQVDAALEKYRADKKITAT
MAV_1170|M.avium_104 YAPDRIDAALSNYFRRGNLTALRELALLWLADQVDTALAKYRAENKITDT
MAB_3251c|M.abscessus_ATCC_199 YAPEKVGSALSNYFRTGNLTALRELALLWLADQVDAALAKYRSDNRITKT
Mflv_0083|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02440|M.leprae_Br4923 --------------------------------------------------
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 WETRERVVVAVTGGTESETLVRRAFRIASKSSAELMVVHVVHGDGLTGIS
Mvan_4762|M.vanbaalenii_PYR-1 WEARERVVVAVTGGPESETLVRRASRIASKSSAELMVVHVVQGDGLSGVS
Mb1056c|M.bovis_AF2122/97 WEARERVVVAVTGGPESETLVRRASRIASKSSAELMVVHVIRGDDLAGVS
Rv1028c|M.tuberculosis_H37Rv WEARERVVVAVTGGPESETLVRRASRIASKSSAELMVVHVIRGDGLAGVS
MMAR_0634|M.marinum_M WEARERVVVAVTGGPESETLVRRAFRIASKASAELMVVHLARGDGLSGVA
MAV_1170|M.avium_104 WEARERVVVAVTGGPESETLVRRASRIASKSSAELMVVHVIRGDGLAGLS
MAB_3251c|M.abscessus_ATCC_199 WEARERVVVAVTGGPESETLVRRASRIAAKSSAELLVVHVVRGDGLVGAS
Mflv_0083|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02440|M.leprae_Br4923 --------------------------------------------------
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 AAQMGKVRELAVSLGATVHTVVGD---DVPTALLDFARDINATQLVLGTS
Mvan_4762|M.vanbaalenii_PYR-1 GPQMGKVRELAASIGATLHTVVGDGAGGVPAALLDFAREMNATQLVLGTS
Mb1056c|M.bovis_AF2122/97 APQLGRVRELATSLGATMHTVVGD---DVPTALLDFAREMNATQLVVGTS
Rv1028c|M.tuberculosis_H37Rv APQLGRVRELATSLGATMHTVVGD---DVPTALLDFAREMNATQLVVGTS
MMAR_0634|M.marinum_M APQMGKVRELAASLGATVHTVVGD---DVPTALLDFAREMNATQLVLGTS
MAV_1170|M.avium_104 ESRMAKIRELASSLDASLHTIVGD---EVPAALLEFAREMNATQLVIGTS
MAB_3251c|M.abscessus_ATCC_199 TAVMTRVRRLANDIGASVQAVTGD---DVPQTLLDFARGVNATQLVLGTS
Mflv_0083|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02440|M.leprae_Br4923 --------------------------------------------------
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 -------------------------------MAERLPRAVQLRVGLVAAT
MSMEG_5395|M.smegmatis_MC2_155 RRSRWARMFDEGIGATVVQQSQKIDVHMVTHEAAKRGFRWSSTSP--RQR
Mvan_4762|M.vanbaalenii_PYR-1 RRSRWARIFDEGIGATVVQKSGRIDVHMVTHEQAGGESLWARVSP--RQR
Mb1056c|M.bovis_AF2122/97 RRSRWARLFDEGIGARTVQESGGIDVHMVTHPAASRASGWSRVSP--RER
Rv1028c|M.tuberculosis_H37Rv RRSRWARLFDEGIGARTVQEPGGIDVHMVTHPAASRASGWSRVSP--RER
MMAR_0634|M.marinum_M RRSRWARVLDEGIGATVVQQSGPIDVHMVTHQEAGRPARWSWLWP--REH
MAV_1170|M.avium_104 RRSRWARLFEEGIGPRIVELSGKIDVHLVTHEESKRGFRASSLAP--RER
MAB_3251c|M.abscessus_ATCC_199 RRSRWARILDEGVAAAVIRDSGAIDVHMVTHGHTSGRLRSWSVPQDGRKR
Mflv_0083|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_02440|M.leprae_Br4923 --------------------------------------------------
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 LALVLCGLLASGVAVTSILRHSLVSRIDSTLLEASR--------------
MSMEG_5395|M.smegmatis_MC2_155 HAASWAAALMVPSLICAFSVAILDPFLDVGGKSALFFVGVLVVALLGGVA
Mvan_4762|M.vanbaalenii_PYR-1 HAVSWLAALAVPGAICAATVLLLDRFLGIGGESAMFFIGVLVVALLGGVA
Mb1056c|M.bovis_AF2122/97 HIASWLAALVVPSVICAITVAWLDRFMGIGGESALFFIGVLIVALLGGVA
Rv1028c|M.tuberculosis_H37Rv HIASWLAALVVPSVICAITVAWLDRFMGIGGESALFFIGVLIVALLGGVA
MMAR_0634|M.marinum_M HLVSWLAAVVVPSLICALTVAWLDRFLAVGGESALFVIGVLVVALLGGVA
MAV_1170|M.avium_104 RVASWLAALIVPSVICAVTVTWLDPYLDTGGESALFFVGVLLVGLLGGIA
MAB_3251c|M.abscessus_ATCC_199 LIINWLAAILVP-PATALFIHFFDTAFGVGSKSALFLIAVLGVSLLGGVS
Mflv_0083|M.gilvum_PYR-GCK ---------------------------------MSVVSALLLAAIVALLA
MLBr_02440|M.leprae_Br4923 -----------------------------------MFSALLLAGVLSGLA
TH_4550|M.thermoresistible__bu --------------------------------VSLRGRITIMSAAVSCAA
MUL_0464|M.ulcerans_Agy99 ---TWAQASWRHSMPSVEGPDPARPPSKFYVRSISPDGRAMTAINDRNAE
:
MSMEG_5395|M.smegmatis_MC2_155 PAALSAVLSGLLLNYFLTSPRHTFTMSDPDSALTIVVLLAVAVAVAALVD
Mvan_4762|M.vanbaalenii_PYR-1 PAALSAVLSGVLLNFFLVEPRHTFTISEPDSAITIVVLLVVAVAVAALVD
Mb1056c|M.bovis_AF2122/97 PAALSALLSGMLLNYFLTEPRYTWTIAEPDAAVTEFVLLAMAVAVAVLVD
Rv1028c|M.tuberculosis_H37Rv PAALSALLSGMLLNYFLTEPRYTWTIAEPDAAVTEFVLLAMAVAVAVLVD
MMAR_0634|M.marinum_M PAALSAVLSGLLLNYFLIEPRYTFTIADPDNAVTTLVLLVVAVAVAALVD
MAV_1170|M.avium_104 PAALSAVLSGLLLNYYLIAPRHSFTIAEPNSAITELVLLLIAVAVAVLVD
MAB_3251c|M.abscessus_ATCC_199 TALVSAVISGLLLNFLFVAPRYSFTIGETDNALTILMMMVTAVAVAALVD
Mflv_0083|M.gilvum_PYR-GCK LAIG--VAIGVRAVPRLRERRQ--RRSAEQSGITVSQMLERIVSFSPIGI
MLBr_02440|M.leprae_Br4923 FVVG--IVAGIRLSPRLIERRQ--RLANEWAGITVLQMLQRIIALMPLGA
TH_4550|M.thermoresistible__bu AALLLAITYALVDLQLSRRGPVVMRRSPPDTAPAEPTGPEVSGVAAWMDR
MUL_0464|M.ulcerans_Agy99 PALPADNDVGSDPTTLPSVNGSNIEWRAVSVHGPQGGLTTVAIDLSDVQH
. . . :
MSMEG_5395|M.smegmatis_MC2_155 GAAKRAREARHASREAELLALFAGSVLRGADLTALLERVRETYAQRAVSL
Mvan_4762|M.vanbaalenii_PYR-1 GAANRTRESRRAAREAELLALFAGAVLRGADLNTLLERVREAYSQQSVTL
Mb1056c|M.bovis_AF2122/97 GAASRTREARRASQEAELLALFAGSVLRGADLATLLQRVRETYSQRAVTM
Rv1028c|M.tuberculosis_H37Rv GAASRTREARRASQEAELLALFAGSVLRGADLATLLQRVRETYSQRAVTM
MMAR_0634|M.marinum_M NAAKRSREAGRASREAELLALFAGSVLRGADLEALLEKVRETYSQRAVSI
MAV_1170|M.avium_104 FAAKRTREARRASQEAELLTLFAGSVLRGADLETLLERVRETYAQRSVSM
MAB_3251c|M.abscessus_ATCC_199 AAATRARQARRASREAELLALFAGGVLVNSDLSALLERVRTTYNQTAVSL
Mflv_0083|M.gilvum_PYR-GCK AVVDNFRDVVYKNDRAQELGLLGDRLLDDRAWVAAQRTLTTGEPHG----
MLBr_02440|M.leprae_Br4923 AVVDTYRDVVYLNEQAKELGLVRDRQLDDQAWRAAQQALG-GDDVE----
TH_4550|M.thermoresistible__bu HRAELQEAATNSLLLYGAVAMAAVTALAAVVAWLVAGRVLSPLHRVTATA
MUL_0464|M.ulcerans_Agy99 TVRSLVWLQIGIGAGVLVVVGLAGFAVVQRSLRPLSEVEQTAAAIASGQL
: :
MSMEG_5395|M.smegmatis_MC2_155 LR----ETSDG--ATIVDCVGQDPCDRVAAADTAVEAG-----DEFWLLL
Mvan_4762|M.vanbaalenii_PYR-1 VR----GEAHG--GGVVGCAGSEPCVTVETADTAIEVGSKDDPEEFWLLL
Mb1056c|M.bovis_AF2122/97 LR----VRQGASTGETVACVGTNPCRDVDSADTAIEVGD----DEFWMLM
Rv1028c|M.tuberculosis_H37Rv LR----VRQGASTGETVACVGTNPCRDVDSADTAIEVGD----DEFWMLM
MMAR_0634|M.marinum_M LR----IEAGTSQGAIVSCVGEDPCVDVDTADTAIDVGD----DEFWMLM
MAV_1170|M.avium_104 LRESEDARAGGTKTQVVACVGRDPCVSVDAADTAIEVGGPDS-SEFQMLL
MAB_3251c|M.abscessus_ATCC_199 LC---------AEGPAVASVGEDPPTRESEADSVFRVDD----GAYALAL
Mflv_0083|M.gilvum_PYR-GCK -------------------FDLSPRKGSRTGRSGLSVRG-----------
MLBr_02440|M.leprae_Br4923 -------------------FDLLPGKRPAAGRSGLSVHG-----------
TH_4550|M.thermoresistible__bu RR-----------------ISRAPALSSGLRERIQLAGP-----------
MUL_0464|M.ulcerans_Agy99 DR-----------------RVPERDPRTEVGQLSLAMNG-----------
MSMEG_5395|M.smegmatis_MC2_155 SGRELPARDRRVLGAVANQAAGLVRQRELTEEAAKANAIAKADELSRSLL
Mvan_4762|M.vanbaalenii_PYR-1 AGRRLDARDRRVLGAVANQAAGLARQRELAEEAGRAEAIARADELRRSLL
Mb1056c|M.bovis_AF2122/97 AGRKLAARDRRVLTAVATQAAGLVKQRELAEEAGQAEAIARADELRRSLL
Rv1028c|M.tuberculosis_H37Rv AGRKLAARDRRVLTAVATQAAGLVKQRELAEEAGQAEAIARADELRRSLL
MMAR_0634|M.marinum_M AGRKLLARDRRVLTAVAKQAAGLIKQRELADEAGKAQAIEQADQLRRALL
MAV_1170|M.avium_104 AGRKLSARDRRVLSAVARQAAGLIRQRELAEEASRTEAIVRADELRRSLL
MAB_3251c|M.abscessus_ATCC_199 NGPPVPSSDARVLQVVAGTAVGLVRSARLAEEASQASALAEADRLRRALL
Mflv_0083|M.gilvum_PYR-GCK YCRLLAEEDRRFAVVYVDDQSEHAR----------------MEATRRDFV
MLBr_02440|M.leprae_Br4923 HARLLSEKDRRFAVVFVHDQSDYVR----------------MEAARRDFV
TH_4550|M.thermoresistible__bu -----ADEVKDLADTFDQMLCRLDR----------------AFAGQRRFV
MUL_0464|M.ulcerans_Agy99 -----MLSQIQVALAASEDSAEKARS---------------SEERMRRFI
. . : * ::
MSMEG_5395|M.smegmatis_MC2_155 SAVSHDLRTPLAAAKAAASSLRSCDIDFSAEDTAELLATIEESVDALTAL
Mvan_4762|M.vanbaalenii_PYR-1 SAVSHDLRTPLAAAKAAVSSLRSEDVGFSPEDTAELLATVEESIDQLSGL
Mb1056c|M.bovis_AF2122/97 SAVSHDLRTPLAAAKVAVSSLRTEDVAFSPEDTAELLATIEESIDQLTAL
Rv1028c|M.tuberculosis_H37Rv SAVSHDLRTPLAAAKVAVSSLRTEDVAFSPEDTAELLATIEESIDQLTAL
MMAR_0634|M.marinum_M SAVSHDLRTPLAAAKAAVSSLRSDDVDFSADDMGELLATIEESVDQLTAL
MAV_1170|M.avium_104 SAVSHDLRTPLAAAKVAVSSLRAEDVAFSPTDTAELLATIEESIDQLTAL
MAB_3251c|M.abscessus_ATCC_199 SAVSHDLRTPLAAVKAAVSSLRSPDIEFSPEDTAELLATVEESADQLTAL
Mflv_0083|M.gilvum_PYR-GCK ANVSHELKTPVGALGVLAEAVLAS--VEDPDTVRHFAEKMVTEADRLANM
MLBr_02440|M.leprae_Br4923 ANVSHELKTPVGAMALLAEALLAS--ADDAETVSRFAEKVLIEANRLGYM
TH_4550|M.thermoresistible__bu GDASHELRTPVAVSRAMIELAMRR--NPGSPELIRLGTDLLEVNERLERL
MUL_0464|M.ulcerans_Agy99 TDASHELRTPLTTIRGFAELYRQG----AARDVAMLLSRIESEASRMGLL
.**:*:**: . . . : : . : :
MSMEG_5395|M.smegmatis_MC2_155 VGNLLDSSRLAAGVIHPELRPVYLEETVQRALLGIRRGPTGYGRSAVDRV
Mvan_4762|M.vanbaalenii_PYR-1 VGNLLDSSRLAAGVVRPELQPVYLEEAVPRALLGISRGSTGL-RAGLDRV
Mb1056c|M.bovis_AF2122/97 VANLLDSSRLAAGVIRPQLRRAYLEEAVQRALVSIGKGATGFYRSGIDRV
Rv1028c|M.tuberculosis_H37Rv VANLLDSSRLAAGVIRPQLRRAYLEEAVQRALVSIGKGATGFYRSGIDRV
MMAR_0634|M.marinum_M VGNLLDSSRLAAGVVRPQLRRVYLEETVQRALLGISRGATGYGRSGLDRV
MAV_1170|M.avium_104 VGNLLDSSRLAAGAIHPDLRRVYLEEAVQRALVSIGKGATGFFRSAIDRV
MAB_3251c|M.abscessus_ATCC_199 VGNLLDSSRLAAGVVKPRAVPVYVDEIAQRALLGATE-------NDRKRV
Mflv_0083|M.gilvum_PYR-GCK VGELIELSRLQGGEPLPDLEAVDVDVVVSEALSRHKVAADN---ADIAIT
MLBr_02440|M.leprae_Br4923 VAELIELSRLQGAERLPNVTDIDVDIIVSEAIARHKVAADT---AAIEVR
TH_4550|M.thermoresistible__bu ITGLLALTNAENG--VIDAHTVDLADVAGHAAAQLAGTAR----ARSVEV
MUL_0464|M.ulcerans_Agy99 VDDLLTLARLDVQRPLERNR-VDLLVLAADAVHDARAIDRK--RAITVEV
: *: :. : . *
MSMEG_5395|M.smegmatis_MC2_155 KVEVGDSVALADGGLLERVLANLIDNALRYAPDGLIR-VTAGR--VANKV
Mvan_4762|M.vanbaalenii_PYR-1 KVEVGDTVVMADSGLLERVLANVIDNALRYAPDGPVR-VTAGR--VADRV
Mb1056c|M.bovis_AF2122/97 KVDVGDAVAMADAGLLERVLANLIDNALRYAPDCVVR-VNAGR--VRERV
Rv1028c|M.tuberculosis_H37Rv KVDVGDAVAMADAGLLERVLANLIDNALRYAPDCVVR-VNAGR--VRERV
MMAR_0634|M.marinum_M KVEVGGAVAIADAGLLERVLANLIDNGLRYAPDSPVR-VYAGR--VGDRV
MAV_1170|M.avium_104 KVDVGDAMVMADAGLLERVLANLIDNALRYAPNCVVR-VNAGQ--VGDRV
MAB_3251c|M.abscessus_ATCC_199 HLDLGGAVVRADPGLLERVLANLVDNALRYS-QGEVR-VSHEE--VDDRT
Mflv_0083|M.gilvum_PYR-GCK TDAPTGFQVLGDQTLLVAAVANLVSNAIAYSPNGSAVSISRRR--NGDNI
MLBr_02440|M.leprae_Br4923 TDPPSGLRVLGDQTLLVTALANLVSNAIAYSPGGSLVSISRRR--RGDNI
TH_4550|M.thermoresistible__bu DTTLSEAVTRGDATLLERLAHNLIENAVKYSGDDSPRVVVTTGSLSDSQV
MUL_0464|M.ulcerans_Agy99 LEGPGTPEVLGDEPRLRQVLSNLVGNALQHTPDSADVTVRVGT--AGENA
. .* * *:: *.: :: : ..
MSMEG_5395|M.smegmatis_MC2_155 LIAVVDEGPGIPRGAEDALFAPFQRLGDTNT--TTGVGLGLSVAKGFVEA
Mvan_4762|M.vanbaalenii_PYR-1 LIAVADEGPGVARGAETELFAPFQRLGDQDT--SSGVGLGLSVARGFVEA
Mb1056c|M.bovis_AF2122/97 LINVIDEGPGVPRGTEEQLFAPFQRPGDHDN--TTGVGLGMSVARGFVEA
Rv1028c|M.tuberculosis_H37Rv LINVIDEGPGVPRGTEEQLFAPFQRPGDHDN--TTGVGLGMSVARGFVEA
MMAR_0634|M.marinum_M LINVADEGPGIPRGAEEQMFAPFQRLGDRDN--RIGVGLGLSVAKGFVEA
MAV_1170|M.avium_104 LINVIDEGPGIPHGAEEQIFEAFQRLGDHDN--TTGVGLGMSVARGFVEA
MAB_3251c|M.abscessus_ATCC_199 LVIVADHGKGLEASKRGAAFDAFQRLGDRDN--TVGVGLGLSVVKGFVEA
Mflv_0083|M.gilvum_PYR-GCK QIAVTDRGIGIAPADQERVFERFFRVDKARSRATGGTGLGLAIVKHVAAN
MLBr_02440|M.leprae_Br4923 EIAVTDRGIGIALEDQERVFERFFRGDKARSRATGGSGLGLAIVKHVAAN
TH_4550|M.thermoresistible__bu FLRVSNNGEPIRDEDLPTLFEPFRRLTRDTR--ASGAGLGLSIAAAIVQA
MUL_0464|M.ulcerans_Agy99 VLEVADKGPGMPAEDAARVFERFYRTDSSRARASGGTGLGLSIVHSLVKA
: * :.* : * * * * ***:::. ..
MSMEG_5395|M.smegmatis_MC2_155 MGGTISAGDTPGGGLTVEIELAVPA-------------------------
Mvan_4762|M.vanbaalenii_PYR-1 MGGTISATDTPGGGMTVEIDLAAPR-------------------------
Mb1056c|M.bovis_AF2122/97 MGGTISATDTPGGGLTVVIDLAAPEDRP----------------------
Rv1028c|M.tuberculosis_H37Rv MGGTISATDTPGGGLTVVIDLAAPEDRP----------------------
MMAR_0634|M.marinum_M MGGTISATDTPGGGLTVVVDLAAA--------------------------
MAV_1170|M.avium_104 MGGTITATDTPGGGLTVMVDMAAPQSEGAA--------------------
MAB_3251c|M.abscessus_ATCC_199 MEGTVNATDTAGGGLTMIVDLPSAGSAPTGAIR-----------------
Mflv_0083|M.gilvum_PYR-GCK HNGSIRLWSQPGTGSTFTLSIPAAPPGEQRSGDAAGG------AADLAQR
MLBr_02440|M.leprae_Br4923 HNGSIGVWSKPGTGSTFTLSIPAAMPLYQDNDEQSGQPRGCDMWLNRPQR
TH_4550|M.thermoresistible__bu HQGTIEATARPDGGLTVEVVLPAPAAARP---------------------
MUL_0464|M.ulcerans_Agy99 HGGDVTLTTAPGEGCCFRVTLPRVSEAAVELTEPVS--------------
* : .. * . : :.
MSMEG_5395|M.smegmatis_MC2_155 --------------------------------------
Mvan_4762|M.vanbaalenii_PYR-1 --------------------------------------
Mb1056c|M.bovis_AF2122/97 --------------------------------------
Rv1028c|M.tuberculosis_H37Rv --------------------------------------
MMAR_0634|M.marinum_M --------------------------------------
MAV_1170|M.avium_104 --------------------------------------
MAB_3251c|M.abscessus_ATCC_199 --------------------------------------
Mflv_0083|M.gilvum_PYR-GCK ED------------------------------------
MLBr_02440|M.leprae_Br4923 EEEEFKSMTPAQAMMQSEVTRGNVNDKCPDCGGRGIAG
TH_4550|M.thermoresistible__bu --------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------