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aa seq not available
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. thermoresistible (build 8) | TH_4550 | - | - | 100% (389) | putative integral membrane sensor signal transduction histidine kinase |
| M. thermoresistible (build 8) | TH_2452 | - | 2e-31 | 31.66% (338) | PUTATIVE putative sensor histidine kinase PhoR |
| M. thermoresistible (build 8) | TH_2428 | - | 1e-29 | 32.15% (311) | PUTATIVE integral membrane sensor signal transduction histidine |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3790c | - | 4e-28 | 30.49% (305) | putative two component sensor kinase |
| M. gilvum PYR-GCK | Mflv_2267 | - | 5e-26 | 30.56% (324) | integral membrane sensor signal transduction histidine kinase |
| M. tuberculosis H37Rv | Rv3764c | - | 4e-28 | 30.49% (305) | two component sensor kinase |
| M. leprae Br4923 | MLBr_00175 | - | 7e-26 | 31.51% (311) | putative two-component system sensor kinase |
| M. abscessus ATCC 19977 | MAB_1077 | - | 2e-25 | 30.70% (316) | two component sensor kinase MprB |
| M. marinum M | MMAR_4528 | mprB | 4e-29 | 33.11% (299) | two-component sensor kinase MprB |
| M. avium 104 | MAV_3405 | - | 1e-31 | 32.39% (352) | hypothetical protein MAV_3405 |
| M. smegmatis MC2 155 | MSMEG_2915 | - | 3e-28 | 32.20% (323) | sensor histidine kinase |
| M. ulcerans Agy99 | MUL_4700 | mprB | 2e-29 | 33.11% (299) | two component sensor kinase MprB |
| M. vanbaalenii PYR-1 | Mvan_3840 | - | 1e-70 | 41.18% (391) | integral membrane sensor signal transduction histidine kinase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_4550|M.thermoresistible__bu -----------------------------------------------VSL
Mvan_3840|M.vanbaalenii_PYR-1 --------------------------------------MTPRSPARRSTI
MMAR_4528|M.marinum_M ----------------------MVGFRRGPR-------APLRATSS-LSL
MUL_4700|M.ulcerans_Agy99 ----------------------MVGFRRGPR-------APLRATSS-LSL
MLBr_00175|M.leprae_Br4923 ----------------------MVRFAWRRR-------ASLRATSS-LSL
MAB_1077|M.abscessus_ATCC_1997 --------------------MSTLRMPRRMRDSSTAIFTPLRATSSSVSL
Mb3790c|M.bovis_AF2122/97 ---------------------------------------MGITAATEMAL
Rv3764c|M.tuberculosis_H37Rv ---------------------------------------MGITAATEMAL
Mflv_2267|M.gilvum_PYR-GCK MSSSPRAERTPAPVLRPPRTWSLRTRLILTQLLLLAVVCAGVGVATEFAL
MSMEG_2915|M.smegmatis_MC2_155 --------------MRTPKSWSLRRQLVVGVSAVVMIALATIGTLSVFTL
MAV_3405|M.avium_104 --------------------------MFSGGPRACRIEGVHLGISARSAA
:
TH_4550|M.thermoresistible__bu RGRITIMSAAVSCAAAALLLAITYALVD----------------------
Mvan_3840|M.vanbaalenii_PYR-1 RWRLTVLYGSAFFIAGAVLICLMYVFLQ----------------------
MMAR_4528|M.marinum_M RWRVMLLAMSMVAMVVVLMSFAVYAVIS----------------------
MUL_4700|M.ulcerans_Agy99 RWRVMLLAMSMVAMVVVLMSFAVYAVIS----------------------
MLBr_00175|M.leprae_Br4923 RWRVMLLAMSMVAMVVVLMAFAVYVVIS----------------------
MAB_1077|M.abscessus_ATCC_1997 RWRVMLLAMSMVAMVVVLMAVASYLLVS----------------------
Mb3790c|M.bovis_AF2122/97 RRHLVAQLDNQLGGTSYRSVLMYPEKMP----------------------
Rv3764c|M.tuberculosis_H37Rv RRHLVAQLDNQLGGTSYRSVLMYPEKMP----------------------
Mflv_2267|M.gilvum_PYR-GCK QRFLMNQLDEQVIEAGRRSSMIFEFGPPPPPGMGMPPPPGVGMPPPPGVG
MSMEG_2915|M.smegmatis_MC2_155 RSSMVGLIDAQLAGAADGFSKTVTKYRT----------------------
MAV_3405|M.avium_104 VAAIVVFCALTVAGAGLDAILYRSLLSG----------------------
: .
TH_4550|M.thermoresistible__bu -----LQLSRR--GPVVMRRSPPDTAPAEPTGPEVSGVAAWMD-------
Mvan_3840|M.vanbaalenii_PYR-1 -----QSLHNRPAGAQGVVSQFLDDRGVR-NRPVVEGLLRAVA-------
MMAR_4528|M.marinum_M -----AALYSDIDNQLQSRAQLLIASGSLAADPGKAIEGTAYS-DVNAML
MUL_4700|M.ulcerans_Agy99 -----AALYSDIDNQLQSRAQLLIASGSLAADPGKAIEGTAYS-DVNAML
MLBr_00175|M.leprae_Br4923 -----AALYSDIDNQLQSRAQLLIASGSLAADPGKAIEGTAYS-DVNAML
MAB_1077|M.abscessus_ATCC_1997 -----TALYRDVDKQLNDRANLLIGSGLLSVDPRRAIEGTAYSADVNAKL
Mb3790c|M.bovis_AF2122/97 ------RPPWRRETHNYIRS-GPGPRFLDAPGQPAGMVAAVVSDGTTVAA
Rv3764c|M.tuberculosis_H37Rv ------RPPWRHETHNYIRS-GPGPRFLDAPGQPAGMVAAVVSDGTTVAA
Mflv_2267|M.gilvum_PYR-GCK MPVPPVGPPPRRGHHMMIRDEGPGPAFLNAPGQAILTVGAVVSDGRADDA
MSMEG_2915|M.smegmatis_MC2_155 -------TPLPGEDE--VPPPGSMKPLIHVLGQAEGNVIALIQDGEVVDS
MAV_3405|M.avium_104 -----VDYAAAERVRDIAKALQSDSREELDNALLTTDQRVVATQLIGPDG
TH_4550|M.thermoresistible__bu --------------------------------------------------
Mvan_3840|M.vanbaalenii_PYR-1 --------------------------------------------------
MMAR_4528|M.marinum_M VNPGRSIYTANQPGQTLPVGAPEKAVIHGDLFLSRRTVSDQRVLAIHLPN
MUL_4700|M.ulcerans_Agy99 VNPGRSIYTANQPGQTLPVGAPEKAVIHGDLFLSRRTVSDQRVLAIHLPN
MLBr_00175|M.leprae_Br4923 VNPGHSIYTANQPGQTLPVGTAEKAVIRGELFMSQRTASDQRILAIHLPN
MAB_1077|M.abscessus_ATCC_1997 IFPGLITFSATQQGQTIPYGTPEQAVTRGDLQQSLRTVNHQRVLALRLDN
Mb3790c|M.bovis_AF2122/97 GYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLGRYRVLAAPSRNG
Rv3764c|M.tuberculosis_H37Rv GYLTGSGSRAALTSTGRSQLERIAGSRTPLTLDLDGLGRYRVLAAPSRNG
Mflv_2267|M.gilvum_PYR-GCK GMIATDGSRTEISDVAARQLATVAVGGRPHTVDLDGLGRYRVVAFPSHME
MSMEG_2915|M.smegmatis_MC2_155 AFFSDGDAQAAPPAAVDTLRDLATTGPTPRNVDIPGLGWYRVVSHPG-DG
MAV_3405|M.avium_104 SVVKRSGSAPATPLVPTADFDFTLRRGLPDDAVSGDDMRVSGQKVATRSG
TH_4550|M.thermoresistible__bu ------RHRAELQEAATNSLLLYGAVAMAAVTALAAVVAWLVAGRVLSPL
Mvan_3840|M.vanbaalenii_PYR-1 ------TESERERQDTLRAMLTWSFVSLGVVGVVAGGFGWLMAGRALAPL
MMAR_4528|M.marinum_M GSSLLISKSLKPTEAVMTKLRAVLLIVGGVGVAVAAVAGGMVTRAGLRPV
MUL_4700|M.ulcerans_Agy99 GSSLLISKSLKPTEAVMTKLRAVLLIVGGVGVAVAAVAGGMVTRAGLRPV
MLBr_00175|M.leprae_Br4923 DSSLLISKSLRPTEAVMTKLRWVLLIVGSLGVAVAAVAGGMVTRAGLRPV
MAB_1077|M.abscessus_ATCC_1997 GSTLIMAKSLDPTDTVLRRLGWVLLIVGGVGVAVAAAAGAMVAGTGLRPV
Mb3790c|M.bovis_AF2122/97 HDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPL
Rv3764c|M.tuberculosis_H37Rv HDVIVTGLSMGNVDATMLQMLIIFGIVTVIALVAATTAGIVIIKRALAPL
Mflv_2267|M.gilvum_PYR-GCK GEAVVAGLPTTDVDDTLFWVAVIFGVVAVVALMAAGTAGAVIVRRQLAPL
MSMEG_2915|M.smegmatis_MC2_155 DESLVTAVSYTPAWEAMMRVTGIVSAMTVVALILTAISTIAIVGFALRPL
MAV_3405|M.avium_104 VYTVLVGGGSEAVEATARTLAILLATTAPVIVAVAAGATYWLVRRSLKSV
. : : : * .:
TH_4550|M.thermoresistible__bu HRVTATARRISRAPALS-----SGLRERIQLAGPADEVKDLADTFDQMLC
Mvan_3840|M.vanbaalenii_PYR-1 QDVTATARRVADR----------NLHERIALDGPDDEIKELADTFDAMLD
MMAR_4528|M.marinum_M GRLTEAAERVART----------DDLRPIPVFG-SDELARLTEAFNLMLR
MUL_4700|M.ulcerans_Agy99 GRLTEAAERVART----------DDLRPIPVFG-SDELARLTEAFNLMLR
MLBr_00175|M.leprae_Br4923 GRLTEAAERVART----------DDLRPIPVFG-SDELARLTEAFNLMLR
MAB_1077|M.abscessus_ATCC_1997 ARLTDAAERVART----------DDLRPIAVTG-SDELARLTISFNTMLR
Mb3790c|M.bovis_AF2122/97 RRVAQTASEVVDLPLDRGEVKLPVRVPEPD-ANPSTEVGQLGSALNRMLD
Rv3764c|M.tuberculosis_H37Rv RRVAQTASEVVDLPLDRGEVKLPVRVPEPD-ANPSTEVGQLGSALNRMLD
Mflv_2267|M.gilvum_PYR-GCK ARVSEAAQQVADLELDRGEVRLPTPIVKVDPAAAQTEVGQLGSALNRMLD
MSMEG_2915|M.smegmatis_MC2_155 RRVAATAAEVATLPLDRENHAITPRVPACD-TDPRTEVGRVGDTLNQLLD
MAV_3405|M.avium_104 DAIRARVADISAS----------DLAERVPVPDGRDEIAALAVTMNEMLS
: . : *: : ::: :*
TH_4550|M.thermoresistible__bu RLDRAF-------AGQRRFVGDASHELRTPVAVSRAMIELAMRRNPGSP-
Mvan_3840|M.vanbaalenii_PYR-1 RLDRAF-------ESQRRFVANASHELRTPLAINRTLIEVALE-DPEVA-
MMAR_4528|M.marinum_M ALAESR-------ERQARLVSDAGHELRTPLTSLRTNVELLMASMEPGAP
MUL_4700|M.ulcerans_Agy99 ALAESR-------ERQARLVSDAGHELRTPLTSLRTNVELLMASMEPGAP
MLBr_00175|M.leprae_Br4923 ALAESR-------ERQARLVTDAGHELRTPLTSLRTNVELLIASMAPEAP
MAB_1077|M.abscessus_ATCC_1997 ALAESR-------DRQARLVTDAGHELRTPLTSLRTNTELLMAAMQPGAP
Mb3790c|M.bovis_AF2122/97 HIAAALSARQASETRVRQFVADASHELRTPLAAIRGYTELTQR-IGDDP-
Rv3764c|M.tuberculosis_H37Rv HIAAALSARQASETCVRQFVADASHELRTPLAAIRGYTELTQR-IGDDP-
Mflv_2267|M.gilvum_PYR-GCK RIAGALSARHASETRVRQFVADASHELRTPLAAIRGYTELAQRKQAELP-
MSMEG_2915|M.smegmatis_MC2_155 HVERALADVAASDRRMRQFITDASHELRTPLAAIHGYAELTRQDSSVLP-
MAV_3405|M.avium_104 RLEAGH-------RAQQRFVGDASHELRSPLTTIISGLEVAEAHPELLD-
: . ::: :*.****:*:: *:
TH_4550|M.thermoresistible__bu ----ELIR-LGTDLLEVNERLERLITGLLALTNAENG-VIDAHTVDLADV
Mvan_3840|M.vanbaalenii_PYR-1 ----ESTRTLGRTLLDVNLRNERLIDGLLVLASSDQQ-LRHRSRVDLGEV
MMAR_4528|M.marinum_M RLPEQEMVGLREDVVAQIEELSTLVGDLVDLTRGDAG-VVVHEPVDMAEV
MUL_4700|M.ulcerans_Agy99 RLPEQEMVGLREDVVAQIEELSTLVGDLVDLTRGDAG-VVVHEPVDMAEV
MLBr_00175|M.leprae_Br4923 RLPDQEMADLRADVLAQIEELSTLVGDLVDLTRDDAG-QVVHEPIDMSEV
MAB_1077|M.abscessus_ATCC_1997 RLPDEEMQALQQDVIAQIEELSTLVGDLVDLARGDGA-DIVHEPVDMVEV
Mb3790c|M.bovis_AF2122/97 ----EAVAHAMSRVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRL
Rv3764c|M.tuberculosis_H37Rv ----EAVAHAMSRVASETERITRLVEDLLLLARLDSGRPLERGPVDMSRL
Mflv_2267|M.gilvum_PYR-GCK ----DDVAHAMSRVESETARMTQLVEDMLLLARLDTGRPLDRDSVDLTRL
MSMEG_2915|M.smegmatis_MC2_155 ----ETTEYSLARIEAEAQRMNSLVSDLLLLARLDEGQELDTTEVDLTEL
MAV_3405|M.avium_104 ------AELAVNTLLPEAHRMRALIDDLLLLARADERNLLRRK--ELVAL
: . *: .:: *: : :: :
TH_4550|M.thermoresistible__bu AGHAAAQLAGTARARSVEVDTTLSEAVTRGDATLLERLAHNLIENAVKYS
Mvan_3840|M.vanbaalenii_PYR-1 TGRALTTVAGFARAAGIRIDSDLPQAHVHGDAALLERLAQNLIDNALRYN
MMAR_4528|M.marinum_M VDRSLERVR--RRRNDIHFDVDVVGWQVYGDAAGLSRAALNLMDNAAKWS
MUL_4700|M.ulcerans_Agy99 VDRSLERVR--RRRNDIHFDVDVVGWQVYGDAAGLSRAALNLMDNAAKWS
MLBr_00175|M.leprae_Br4923 LYRSLERVR--RRRNDIHFDVQAIGWQIYGDAAGLSRAVLNLMDNAAKWS
MAB_1077|M.abscessus_ATCC_1997 VEGTLERVR--RRRNDIEFDVVMQPWQVYGDAAGLSRAVLNLLDNAAKWS
Mb3790c|M.bovis_AF2122/97 AVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHT
Rv3764c|M.tuberculosis_H37Rv AVDAVSDAHVAGPDHQWALDLPPEPVVIPGDAARLHQVVTNLLANARVHT
Mflv_2267|M.gilvum_PYR-GCK VVDAVSDAHVAAPDHVWELDLPDEPLTVCGDEARLHQVLANLLANAGIHT
MSMEG_2915|M.smegmatis_MC2_155 VADAVNDAAVSAPTHHWSVRVPDDPVWVRADHARLHQTLANLLSNARVHT
MAV_3405|M.avium_104 DDLAEAEAARVRRDADCAVHTDIRPARLLADPAAMTRMIRNLVDNAVRHA
: . .* : : : **: **
TH_4550|M.thermoresistible__bu GDDSPRVVVTTGS---LSDSQVFLRVSNNGEPIRDEDLPTLFEPFRRLTR
Mvan_3840|M.vanbaalenii_PYR-1 VPEDGWVSVTVG----TQDGFATLRVENSGPVVAAAEIPGLFEPFRRLAA
MMAR_4528|M.marinum_M -PPGGRVGIRLRQ---LDPSHAELVVSDNGPGISPQERRLVFERFYRSTS
MUL_4700|M.ulcerans_Agy99 -PPGGRVGIRLRQ---LDPSHAELVVSDNGPGISPQERRLVFERFYRSTS
MLBr_00175|M.leprae_Br4923 -PSGGRVVVTMRQ---FDPSHVELVVSDYGPGIPPQERRLVFERFYRSTT
MAB_1077|M.abscessus_ATCC_1997 -PSGTAVSVRLAQ---VDAAHAELVISDHGPGIPPAERDLVFERFYRATP
Mb3790c|M.bovis_AF2122/97 -GPGTIVTTRLST---GPT-HVVLQVIDNGPGIPAALQSEVFERFARGDT
Rv3764c|M.tuberculosis_H37Rv -GPGTIVTTRLST---GPT-HVVLQVIDNGPGIPAALQSEVFERFARGDT
Mflv_2267|M.gilvum_PYR-GCK -PAGTTVTTSLTA---TDTGDVLVRVVDDGPGIPARLQPDVFERFARGDT
MSMEG_2915|M.smegmatis_MC2_155 -PEGTSVQTTLVVHGNGDTSHAEVTVSDNGPGINPDLLPHLFERFVRADK
MAV_3405|M.avium_104 ---VSCVAIEVGS----RDGTAVLTVGDDGPGIPPAQRSRVFERFVRLDT
* . : : : * : :** * *
TH_4550|M.thermoresistible__bu DTRAS-------GAGLGLSIAAAIVQAHQGTIEATARPD---------GG
Mvan_3840|M.vanbaalenii_PYR-1 ADRVAESPAPGRGAGLGLSIVRSVAVAHGGDVRAEARPA---------GG
MMAR_4528|M.marinum_M ARAMP-------GSGLGLAIVKQVVLNHGGSLRIEDTVP-----GGQPPG
MUL_4700|M.ulcerans_Agy99 ARAMP-------GSGLGLAIVKQVVLNHGGSLRIEDTVP-----GGQPPG
MLBr_00175|M.leprae_Br4923 ARSLP-------GSGLGLAIVKQVVINHGGLLRVEDTAP-----GVQPPG
MAB_1077|M.abscessus_ATCC_1997 ARGMP-------GSGLGLAIVKQVVLKHGGAIKVEETDPGAVIDGEPAPG
Mb3790c|M.bovis_AF2122/97 SRSRQ-----AGSTGLGLAIVSAVVKAHNGTITVSSSPG----------Y
Rv3764c|M.tuberculosis_H37Rv SRSRQ-----AGSTGLGLAIVSAVVKAHNGTITVSSSPG----------Y
Mflv_2267|M.gilvum_PYR-GCK SRSRR-----GGSTGLGLAIVAAVVRAHHGTISLHSVPG----------R
MSMEG_2915|M.smegmatis_MC2_155 SRSRA-----AGSFGLGLSIAASIVEAHGGTISAQSGSG----------K
MAV_3405|M.avium_104 DRARS-----GGGAGLGLAIVAEVVAAHGGTVTIGDRPG---------GG
. ****:*. :. * * :
TH_4550|M.thermoresistible__bu LTVEVVLPAPAAARP-----------------------------------
Mvan_3840|M.vanbaalenii_PYR-1 LDVAVTLTACQ---------------------------------------
MMAR_4528|M.marinum_M TAICMLLPGRPMPDSAYPAAPDD--------KKTEPVDTRGANGANSRGS
MUL_4700|M.ulcerans_Agy99 TAICMLLPGRPMPDSAYPAAPDD--------KKTEPVDTRGANGANSRGS
MLBr_00175|M.leprae_Br4923 TSIYVLLPGRPMPVSAYSTLADQDMGEANFQDKIGPAVQVSGKSANFRDS
MAB_1077|M.abscessus_ATCC_1997 TSMHVLLPGRPGP-------------------IVRPNMGDTAGRRNSGPN
Mb3790c|M.bovis_AF2122/97 TEFAVRLP-LDGWQPLESSPR-----------------------------
Rv3764c|M.tuberculosis_H37Rv TEFAVRLP-LDGWQPLESSPR-----------------------------
Mflv_2267|M.gilvum_PYR-GCK TEFAVVLP-GDTQAVHSVGPR-----------------------------
MSMEG_2915|M.smegmatis_MC2_155 TSFVIRLPSIPVTAPHKTSV------------------------------
MAV_3405|M.avium_104 TTLTVALPQHPAQHSSR---------------------------------
. : *.
TH_4550|M.thermoresistible__bu ------------------
Mvan_3840|M.vanbaalenii_PYR-1 ------------------
MMAR_4528|M.marinum_M ANVISVDSQSARAR----
MUL_4700|M.ulcerans_Agy99 ANVISVDSQSARAR----
MLBr_00175|M.leprae_Br4923 AHVISVDYQSARAR----
MAB_1077|M.abscessus_ATCC_1997 AREISVDSQSVPAAWRPS
Mb3790c|M.bovis_AF2122/97 ------------------
Rv3764c|M.tuberculosis_H37Rv ------------------
Mflv_2267|M.gilvum_PYR-GCK ------------------
MSMEG_2915|M.smegmatis_MC2_155 ------------------
MAV_3405|M.avium_104 ------------------