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VTLLFADLCAIFTPYRWMIEHVTTKRGQLRIYLGAAPGVGKTYAMLGEAHRRLERGTDVVAAVVETHGRN KTAKLLEGIEMIPPRYVEYRGARFPELDVEAVLRRHPQVVLVDELAHTNTPGSKNPKRWQDVQEILDAGI TVISTVNIQHLEGLNDVVEQITGIEQKEKIPDEIVRAADQVELVDITPEALRRRLAHGNVYAAERVDAAL SNYFRTGNLTALREIALLWLADQVDAALEKYRADKKITATWEARERVVVAVTGGPESETLVRRASRIASK SSAELMVVHVIRGDDLAGVSAPQLGRVRELATSLGATMHTVVGDDVPTALLDFAREMNATQLVVGTSRRS RWARLFDEGIGARTVQESGGIDVHMVTHPAASRASGWSRVSPRERHIASWLAALVVPSVICAITVAWLDR FMGIGGESALFFIGVLIVALLGGVAPAALSALLSGMLLNYFLTEPRYTWTIAEPDAAVTEFVLLAMAVAV AVLVDGAASRTREARRASQEAELLALFAGSVLRGADLATLLQRVRETYSQRAVTMLRVRQGASTGETVAC VGTNPCRDVDSADTAIEVGDDEFWMLMAGRKLAARDRRVLTAVATQAAGLVKQRELAEEAGQAEAIARAD ELRRSLLSAVSHDLRTPLAAAKVAVSSLRTEDVAFSPEDTAELLATIEESIDQLTALVANLLDSSRLAAG VIRPQLRRAYLEEAVQRALVSIGKGATGFYRSGIDRVKVDVGDAVAMADAGLLERVLANLIDNALRYAPD CVVRVNAGRVRERVLINVIDEGPGVPRGTEEQLFAPFQRPGDHDNTTGVGLGMSVARGFVEAMGGTISAT DTPGGGLTVVIDLAAPEDRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1056c | kdpD | - | 100% (860) | sensor protein KDPD |
| M. bovis AF2122 / 97 | Mb3273c | mtrB | 2e-17 | 30.57% (229) | two component sensory transduction histidine kinase MTRB |
| M. bovis AF2122 / 97 | Mb3790c | - | 3e-16 | 29.06% (234) | putative two component sensor kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4711 | - | 5e-18 | 31.08% (222) | integral membrane sensor signal transduction histidine kinase |
| M. tuberculosis H37Rv | Rv1028c | kdpD | 0.0 | 99.77% (860) | sensor protein KDPD |
| M. leprae Br4923 | MLBr_00774 | mtrB | 1e-17 | 29.34% (242) | putative two-component system sensor kinase |
| M. abscessus ATCC 19977 | MAB_3251c | - | 0.0 | 62.60% (837) | sensor protein KdpD |
| M. marinum M | MMAR_0634 | kdpD | 0.0 | 82.43% (831) | two-component system response phosphate sensor kinase, KdpD |
| M. avium 104 | MAV_1170 | - | 0.0 | 80.24% (840) | sensor protein KdpD |
| M. smegmatis MC2 155 | MSMEG_5395 | - | 0.0 | 77.31% (833) | sensor protein KdpD |
| M. thermoresistible (build 8) | TH_4550 | - | 1e-20 | 30.69% (290) | PUTATIVE putative integral membrane sensor signal transduction |
| M. ulcerans Agy99 | MUL_0464 | phoR | 1e-20 | 28.88% (322) | two component system response phosphate sensor kinase, PhoR |
| M. vanbaalenii PYR-1 | Mvan_4762 | - | 0.0 | 79.38% (839) | osmosensitive K+ channel signal transduction histidine kinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1056c|M.bovis_AF2122/97 MTLLFADLCAIFTPYRWMIEHVTTKRGQLRIYLGAAPGVGKTYAMLGEAH
Rv1028c|M.tuberculosis_H37Rv MTLLFADLCAIFTPYRWMIEHVTTKRGQLRIYLGAAPGVGKTYAMLGEAH
MMAR_0634|M.marinum_M -----------------MTPDYPRKRGELRIYLGAAPGVGKTFAMLGEAQ
MSMEG_5395|M.smegmatis_MC2_155 -----------MTTRASNAS----KRGELRIYLGAAPGVGKTYAMLGEAH
Mvan_4762|M.vanbaalenii_PYR-1 -----------MDDESVAASPHKAKRGELRIYLGAAPGVGKTYAMLGEAH
MAV_1170|M.avium_104 ---------------MTDVRDHHPKRGELRIYLGAAPGVGKTYSMLGEAH
MAB_3251c|M.abscessus_ATCC_199 ------------------MPDGLRARGTLRIYLGAAPGVGKTFAMLNEAH
Mflv_4711|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_00774|M.leprae_Br4923 --------------------------------------------------
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
Mb1056c|M.bovis_AF2122/97 RRLERGTDVVAAVVETHGRNKTAKLLEGIEMIPPRYVEYRGARFPELDVE
Rv1028c|M.tuberculosis_H37Rv RRLERGTDVVAAVVETHGRNKTAKLLEGIEMIPPRYVEYRGARFPELDVE
MMAR_0634|M.marinum_M RRLERGTDVVAAVVETHGRKRTAELLEGIERIPPKFIEYRGSRFAELDVE
MSMEG_5395|M.smegmatis_MC2_155 RRLDRGTDLVAAVVETHGRKNTAELLAGIEVIPPRYIEYRGGRFPELDVP
Mvan_4762|M.vanbaalenii_PYR-1 RRLERGTDVVAAVVETHGRKKTAELFEGIEIVPPKLIAYRGSDFAELDVE
MAV_1170|M.avium_104 RRLERGTDLVAGVVETHGRAKTAELLEGIEIIPPRYIEYRGGRFPELDVP
MAB_3251c|M.abscessus_ATCC_199 RRAGRGTDVVAAVVETHGRSKTAELLDGLELIPPKEMVHRGTAMYELDVD
Mflv_4711|M.gilvum_PYR-GCK --------------------------------------------------
MLBr_00774|M.leprae_Br4923 --------------------------------------------------
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
Mb1056c|M.bovis_AF2122/97 AVLRRHPQVVLVDELAHTNTPGSKNPKRWQDVQEILDAGITVISTVNIQH
Rv1028c|M.tuberculosis_H37Rv AVLRRHPQVVLVDELAHTNTPGSKNPKRWQDVQEILDAGITVISTVNIQH
MMAR_0634|M.marinum_M AVLRRQPQVVLVDELAHTNTPGSKNPKRWQDVEELLDAGITVISTVNVQH
MSMEG_5395|M.smegmatis_MC2_155 AVLDRKPQVVLVDELAHTNTPGSKNAKRWQDVDELLNAGITVISTVNVQH
Mvan_4762|M.vanbaalenii_PYR-1 AVLRRNPQVVLVDELAHTNTPGSKNTKRWQDIEELLDAGITVITTVNVQH
MAV_1170|M.avium_104 AVLARHPQVVLVDELAHTNTPGSKNPKRWQDVEELLDAGITVISTVNVQH
MAB_3251c|M.abscessus_ATCC_199 AVLERRPALVLIDEMAHTNVPGSRNPKRWQDIDEILDAGIDVLTTINVQH
Mflv_4711|M.gilvum_PYR-GCK -----------------------------------------MIFGSRRRI
MLBr_00774|M.leprae_Br4923 -----------------------------------------MIFSSRRRI
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
Mb1056c|M.bovis_AF2122/97 LEGLNDVVEQITGIEQKEKIPDEIVRAADQVELVDITPEALRRRLAHGNV
Rv1028c|M.tuberculosis_H37Rv LEGLNDVVEQITGIEQKEKIPDEIVRAADQVELVDITPEALRRRLAHGNV
MMAR_0634|M.marinum_M LESLNDVVAQITGIEQQEKVPDEIVRAAEQVELVDITPEALRRRLAHGNV
MSMEG_5395|M.smegmatis_MC2_155 LDSLNDVVAAITGIEQQETVPDEVVRSADQIELVDITPEALRRRLSHGNV
Mvan_4762|M.vanbaalenii_PYR-1 LESLNDVVTQITGIEQQEKVPDEVVRAADQVELVDITPEALRRRLAHGNV
MAV_1170|M.avium_104 LESLNDVVAQITGIEQKETVPDSVVRQASQVELIDITPEALRRRLSHGNV
MAB_3251c|M.abscessus_ATCC_199 LESLNDVVEQITGIVQRETVPDAVVRRAEQVELVDITPEALRRRMVHGNV
Mflv_4711|M.gilvum_PYR-GCK HR---RSAPLIRGLAALGRALSLAWRRSLQLRVVTLT-------------
MLBr_00774|M.leprae_Br4923 RGRWGRSGPMMRGMGALTRVVGVVWRRSLQLRVVALT-------------
TH_4550|M.thermoresistible__bu ----VSLRGRITIMSAAVSCAAAALLLAITYALVDLQ-------------
MUL_0464|M.ulcerans_Agy99 ---------MAERLPRAVQLRVGLVAATLALVLCGLLAS-----------
: : : :
Mb1056c|M.bovis_AF2122/97 YAAERVDAALSNYFRTGNLTALREIALLWLADQVDAALEKYRADKKITAT
Rv1028c|M.tuberculosis_H37Rv YAAERVDAALSNYFRTGNLTALREIALLWLADQVDAALEKYRADKKITAT
MMAR_0634|M.marinum_M YAAERVDAALANYFRTGNLTALRELALLWLADQVDAALEKYRADKKITAT
MSMEG_5395|M.smegmatis_MC2_155 YAPERIDAALSNYFRRGNLTALRELALLWLADQVDAALAKYRADNKITAL
Mvan_4762|M.vanbaalenii_PYR-1 YAPERVDAALSNYFRRGNLTALRELALLWLADQVDSALEKYRADNKITDT
MAV_1170|M.avium_104 YAPDRIDAALSNYFRRGNLTALRELALLWLADQVDTALAKYRAENKITDT
MAB_3251c|M.abscessus_ATCC_199 YAPEKVGSALSNYFRTGNLTALRELALLWLADQVDAALAKYRSDNRITKT
Mflv_4711|M.gilvum_PYR-GCK -------------------LGLSLAVILVLGFVLTSQITDRILEVKVGAA
MLBr_00774|M.leprae_Br4923 -------------------FGLSLAVILALGFVLTSQLTSRVLDVKVRVA
TH_4550|M.thermoresistible__bu ---------------------LSRRGPVVMRRSPPDTAPAEPTGPEVSGV
MUL_0464|M.ulcerans_Agy99 ----------------------GVAVTSILRHSLVSRIDSTLLEASRTWA
:
Mb1056c|M.bovis_AF2122/97 WEARERVVVAVTGGPESETLVRRASRIASKSSAELMVVHVIRGDDLAGVS
Rv1028c|M.tuberculosis_H37Rv WEARERVVVAVTGGPESETLVRRASRIASKSSAELMVVHVIRGDGLAGVS
MMAR_0634|M.marinum_M WEARERVVVAVTGGPESETLVRRAFRIASKASAELMVVHLARGDGLSGVA
MSMEG_5395|M.smegmatis_MC2_155 WETRERVVVAVTGGTESETLVRRAFRIASKSSAELMVVHVVHGDGLTGIS
Mvan_4762|M.vanbaalenii_PYR-1 WEARERVVVAVTGGPESETLVRRASRIASKSSAELMVVHVVQGDGLSGVS
MAV_1170|M.avium_104 WEARERVVVAVTGGPESETLVRRASRIASKSSAELMVVHVIRGDGLAGLS
MAB_3251c|M.abscessus_ATCC_199 WEARERVVVAVTGGPESETLVRRASRIAAKSSAELLVVHVVRGDGLVGAS
Mflv_4711|M.gilvum_PYR-GCK TEEIERARTTVSGIVGGEETRSLDSSLQLARNTLIDR-KADAGAGLAGTF
MLBr_00774|M.leprae_Br4923 IEQIERARTTVTGIVNGEETRSLDSSLQLARNTLTSKTDPTSGAGLVGAF
TH_4550|M.thermoresistible__bu AAWMDRHRAELQEAATNSLLLYGAVAMAAVTALAAVVAWLVAGRVLS---
MUL_0464|M.ulcerans_Agy99 QASWRHSMPSVEGPDPARPPSKFYVRSISPDGRAMTAINDRNAEPALPAD
: : .
Mb1056c|M.bovis_AF2122/97 APQLGRVRELATSLGATMHTVVGD---DVPTALLDFAREMNATQLVVGTS
Rv1028c|M.tuberculosis_H37Rv APQLGRVRELATSLGATMHTVVGD---DVPTALLDFAREMNATQLVVGTS
MMAR_0634|M.marinum_M APQMGKVRELAASLGATVHTVVGD---DVPTALLDFAREMNATQLVLGTS
MSMEG_5395|M.smegmatis_MC2_155 AAQMGKVRELAVSLGATVHTVVGD---DVPTALLDFARDINATQLVLGTS
Mvan_4762|M.vanbaalenii_PYR-1 GPQMGKVRELAASIGATLHTVVGDGAGGVPAALLDFAREMNATQLVLGTS
MAV_1170|M.avium_104 ESRMAKIRELASSLDASLHTIVGD---EVPAALLEFAREMNATQLVIGTS
MAB_3251c|M.abscessus_ATCC_199 TAVMTRVRRLANDIGASVQAVTGD---DVPQTLLDFARGVNATQLVLGTS
Mflv_4711|M.gilvum_PYR-GCK DAVL-----VVAGDGPRAATAAGP-ADQVPAALRDFVKAG---------Q
MLBr_00774|M.leprae_Br4923 DAVL-----IVPGDGPRTATTAGP-VDQVPNSLRGFIKAG---------Q
TH_4550|M.thermoresistible__bu ----------------PLHRVTAT-------------------------A
MUL_0464|M.ulcerans_Agy99 NDVG--------SDPTTLPSVNGS-----------------------NIE
.
Mb1056c|M.bovis_AF2122/97 RRSRWARLFDEGIGARTVQESGGIDVHMVTHPAASRASGWSRVSP--RER
Rv1028c|M.tuberculosis_H37Rv RRSRWARLFDEGIGARTVQEPGGIDVHMVTHPAASRASGWSRVSP--RER
MMAR_0634|M.marinum_M RRSRWARVLDEGIGATVVQQSGPIDVHMVTHQEAGRPARWSWLWP--REH
MSMEG_5395|M.smegmatis_MC2_155 RRSRWARMFDEGIGATVVQQSQKIDVHMVTHEAAKRGFRWSSTSP--RQR
Mvan_4762|M.vanbaalenii_PYR-1 RRSRWARIFDEGIGATVVQKSGRIDVHMVTHEQAGGESLWARVSP--RQR
MAV_1170|M.avium_104 RRSRWARLFEEGIGPRIVELSGKIDVHLVTHEESKRGFRASSLAP--RER
MAB_3251c|M.abscessus_ATCC_199 RRSRWARILDEGVAAAVIRDSGAIDVHMVTHGHTSGRLRSWSVPQDGRKR
Mflv_4711|M.gilvum_PYR-GCK VSYQYATVHTDGFSGPALIVG-----------------------------
MLBr_00774|M.leprae_Br4923 AAYQYATVHTEGFSGPALIIG-----------------------------
TH_4550|M.thermoresistible__bu RRISRAPALSSGLRERIQLAG-----------------------------
MUL_0464|M.ulcerans_Agy99 WRAVSVHGPQGGLTTVAIDLS-----------------------------
. *.
Mb1056c|M.bovis_AF2122/97 HIASWLAALVVPSVICAITVAWLDRFMGIGGESALFFIGVLIVALLGGVA
Rv1028c|M.tuberculosis_H37Rv HIASWLAALVVPSVICAITVAWLDRFMGIGGESALFFIGVLIVALLGGVA
MMAR_0634|M.marinum_M HLVSWLAAVVVPSLICALTVAWLDRFLAVGGESALFVIGVLVVALLGGVA
MSMEG_5395|M.smegmatis_MC2_155 HAASWAAALMVPSLICAFSVAILDPFLDVGGKSALFFVGVLVVALLGGVA
Mvan_4762|M.vanbaalenii_PYR-1 HAVSWLAALAVPGAICAATVLLLDRFLGIGGESAMFFIGVLVVALLGGVA
MAV_1170|M.avium_104 RVASWLAALIVPSVICAVTVTWLDPYLDTGGESALFFVGVLLVGLLGGIA
MAB_3251c|M.abscessus_ATCC_199 LIINWLAAILVP-PATALFIHFFDTAFGVGSKSALFLIAVLGVSLLGGVS
Mflv_4711|M.gilvum_PYR-GCK -------------------------------------------------S
MLBr_00774|M.leprae_Br4923 -------------------------------------------------T
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
Mb1056c|M.bovis_AF2122/97 PAALSALLSGMLLNYFLTEPRYTWTIAEPDAAVTEFVLLAMAVAVAVLVD
Rv1028c|M.tuberculosis_H37Rv PAALSALLSGMLLNYFLTEPRYTWTIAEPDAAVTEFVLLAMAVAVAVLVD
MMAR_0634|M.marinum_M PAALSAVLSGLLLNYFLIEPRYTFTIADPDNAVTTLVLLVVAVAVAALVD
MSMEG_5395|M.smegmatis_MC2_155 PAALSAVLSGLLLNYFLTSPRHTFTMSDPDSALTIVVLLAVAVAVAALVD
Mvan_4762|M.vanbaalenii_PYR-1 PAALSAVLSGVLLNFFLVEPRHTFTISEPDSAITIVVLLVVAVAVAALVD
MAV_1170|M.avium_104 PAALSAVLSGLLLNYYLIAPRHSFTIAEPNSAITELVLLLIAVAVAVLVD
MAB_3251c|M.abscessus_ATCC_199 TALVSAVISGLLLNFLFVAPRYSFTIGETDNALTILMMMVTAVAVAALVD
Mflv_4711|M.gilvum_PYR-GCK PTSSPVTNLELYLIFPLNSEDSTIALVRGTMATGGVVLLGLLAAIALLVA
MLBr_00774|M.leprae_Br4923 PTSSQVTNLELYLIFPLKNEQATVTLVRGTMATGGMVLLVLLSGIALLVS
TH_4550|M.thermoresistible__bu --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 ---------------DVQHTVRSLVWLQIGIGAGVLVVVGLAGFAVVQRS
Mb1056c|M.bovis_AF2122/97 GAASRTREARRASQEAELLALFAGSVLRGADLATLLQRVRETYSQRAVTM
Rv1028c|M.tuberculosis_H37Rv GAASRTREARRASQEAELLALFAGSVLRGADLATLLQRVRETYSQRAVTM
MMAR_0634|M.marinum_M NAAKRSREAGRASREAELLALFAGSVLRGADLEALLEKVRETYSQRAVSI
MSMEG_5395|M.smegmatis_MC2_155 GAAKRAREARHASREAELLALFAGSVLRGADLTALLERVRETYAQRAVSL
Mvan_4762|M.vanbaalenii_PYR-1 GAANRTRESRRAAREAELLALFAGAVLRGADLNTLLERVREAYSQQSVTL
MAV_1170|M.avium_104 FAAKRTREARRASQEAELLTLFAGSVLRGADLETLLERVRETYAQRSVSM
MAB_3251c|M.abscessus_ATCC_199 AAATRARQARRASREAELLALFAGGVLVNSDLSALLERVRTTYNQTAVSL
Mflv_4711|M.gilvum_PYR-GCK RQIVLP--VRSASRIAERFAEGHLTERMPVRGEDDMARLAVSFNDMAESL
MLBr_00774|M.leprae_Br4923 RQVVVP--VRSASRIAERFAEGHLSERMPVRGEDDMARLAVSFNDMAESL
TH_4550|M.thermoresistible__bu -------------------------------PADEVKDLADTFDQMLCRL
MUL_0464|M.ulcerans_Agy99 LRPLSEVEQTAAAIASGQLDRRVPERDPRTEVGQLSLAMNGMLSQIQVAL
: : :
Mb1056c|M.bovis_AF2122/97 LR----VRQGASTGETVACVGTNPCRDVDSADTAIEVGD----DEFWMLM
Rv1028c|M.tuberculosis_H37Rv LR----VRQGASTGETVACVGTNPCRDVDSADTAIEVGD----DEFWMLM
MMAR_0634|M.marinum_M LR----IEAGTSQGAIVSCVGEDPCVDVDTADTAIDVGD----DEFWMLM
MSMEG_5395|M.smegmatis_MC2_155 LR----ETSDG--ATIVDCVGQDPCDRVAAADTAVEAG-----DEFWLLL
Mvan_4762|M.vanbaalenii_PYR-1 VR----GEAHG--GGVVGCAGSEPCVTVETADTAIEVGSKDDPEEFWLLL
MAV_1170|M.avium_104 LRESEDARAGGTKTQVVACVGRDPCVSVDAADTAIEVGGPDS-SEFQMLL
MAB_3251c|M.abscessus_ATCC_199 LC---------AEGPAVASVGEDPPTRESEADSVFRVDD----GAYALAL
Mflv_4711|M.gilvum_PYR-GCK HR------------------------------------------------
MLBr_00774|M.leprae_Br4923 SR------------------------------------------------
TH_4550|M.thermoresistible__bu DR------------------------------------------------
MUL_0464|M.ulcerans_Agy99 AAS-----------------------------------------------
Mb1056c|M.bovis_AF2122/97 AGRKLAARDRRVLTAVATQAAGLVKQRELAEEAGQAEAIARADELRRSLL
Rv1028c|M.tuberculosis_H37Rv AGRKLAARDRRVLTAVATQAAGLVKQRELAEEAGQAEAIARADELRRSLL
MMAR_0634|M.marinum_M AGRKLLARDRRVLTAVAKQAAGLIKQRELADEAGKAQAIEQADQLRRALL
MSMEG_5395|M.smegmatis_MC2_155 SGRELPARDRRVLGAVANQAAGLVRQRELTEEAAKANAIAKADELSRSLL
Mvan_4762|M.vanbaalenii_PYR-1 AGRRLDARDRRVLGAVANQAAGLARQRELAEEAGRAEAIARADELRRSLL
MAV_1170|M.avium_104 AGRKLSARDRRVLSAVARQAAGLIRQRELAEEASRTEAIVRADELRRSLL
MAB_3251c|M.abscessus_ATCC_199 NGPPVPSSDARVLQVVAGTAVGLVRSARLAEEASQASALAEADRLRRALL
Mflv_4711|M.gilvum_PYR-GCK ----------------------------------QITQLEEFGNLQRRFT
MLBr_00774|M.leprae_Br4923 ----------------------------------QITQLEEFGNLQRRFT
TH_4550|M.thermoresistible__bu -----------------------------------------AFAGQRRFV
MUL_0464|M.ulcerans_Agy99 --------------------------------EDSAEKARSSEERMRRFI
* :
Mb1056c|M.bovis_AF2122/97 SAVSHDLRTPLAAAKVAVSSLRTEDVAFSPEDTAELLATIEESIDQLT--
Rv1028c|M.tuberculosis_H37Rv SAVSHDLRTPLAAAKVAVSSLRTEDVAFSPEDTAELLATIEESIDQLT--
MMAR_0634|M.marinum_M SAVSHDLRTPLAAAKAAVSSLRSDDVDFSADDMGELLATIEESVDQLT--
MSMEG_5395|M.smegmatis_MC2_155 SAVSHDLRTPLAAAKAAASSLRSCDIDFSAEDTAELLATIEESVDALT--
Mvan_4762|M.vanbaalenii_PYR-1 SAVSHDLRTPLAAAKAAVSSLRSEDVGFSPEDTAELLATVEESIDQLS--
MAV_1170|M.avium_104 SAVSHDLRTPLAAAKVAVSSLRAEDVAFSPTDTAELLATIEESIDQLT--
MAB_3251c|M.abscessus_ATCC_199 SAVSHDLRTPLAAVKAAVSSLRSPDIEFSPEDTAELLATVEESADQLT--
Mflv_4711|M.gilvum_PYR-GCK SDVSHELRTPLTTVRMAADLIHDHIHDSPDDLDPALRRSTELMVNELDRF
MLBr_00774|M.leprae_Br4923 SDVSHELRTPLTTVRMAADLIYDHSS----DLDPTLRRSTELMVSELDRF
TH_4550|M.thermoresistible__bu GDASHELRTPVAVSRAMIELAMRRNPG-----SPELIRLGTDLLEVNERL
MUL_0464|M.ulcerans_Agy99 TDASHELRTPLTTIRGFAELYRQGAAR----DVAMLLSRIESEASRMG--
.**:****::. : . * .
Mb1056c|M.bovis_AF2122/97 -ALVANLLDSSRLAAGVIRPQLRRAYLEEAVQRALVSIGKGATGFYRSGI
Rv1028c|M.tuberculosis_H37Rv -ALVANLLDSSRLAAGVIRPQLRRAYLEEAVQRALVSIGKGATGFYRSGI
MMAR_0634|M.marinum_M -ALVGNLLDSSRLAAGVVRPQLRRVYLEETVQRALLGISRGATGYGRSGL
MSMEG_5395|M.smegmatis_MC2_155 -ALVGNLLDSSRLAAGVIHPELRPVYLEETVQRALLGIRRGPTGYGRSAV
Mvan_4762|M.vanbaalenii_PYR-1 -GLVGNLLDSSRLAAGVVRPELQPVYLEEAVPRALLGISRGSTGL-RAGL
MAV_1170|M.avium_104 -ALVGNLLDSSRLAAGAIHPDLRRVYLEEAVQRALVSIGKGATGFFRSAI
MAB_3251c|M.abscessus_ATCC_199 -ALVGNLLDSSRLAAGVVKPRAVPVYVDEIAQRALLGATE-------NDR
Mflv_4711|M.gilvum_PYR-GCK ESLLNDLLEISRHDAGVAELAVEAVDLRSIVQRALDNVGHLAEG--ADVE
MLBr_00774|M.leprae_Br4923 ETLLNDLLEISRHDAGVAELSVEAVDLRVMVNNALGNVGHLAEE--AGIE
TH_4550|M.thermoresistible__bu ERLITGLLALTNAENGVID--AHTVDLADVAGHAAAQLAGTAR----ARS
MUL_0464|M.ulcerans_Agy99 -LLVDDLLTLARLDV-QRPLERNRVDLLVLAADAVHDARAIDRK--RAIT
*: .** :. . : . *
Mb1056c|M.bovis_AF2122/97 DRVKVDVGDAVAMADAGLLERVLANLIDNALRYAPDCVVRVNAGR---VR
Rv1028c|M.tuberculosis_H37Rv DRVKVDVGDAVAMADAGLLERVLANLIDNALRYAPDCVVRVNAGR---VR
MMAR_0634|M.marinum_M DRVKVEVGGAVAIADAGLLERVLANLIDNGLRYAPDSPVRVYAGR---VG
MSMEG_5395|M.smegmatis_MC2_155 DRVKVEVGDSVALADGGLLERVLANLIDNALRYAPDGLIRVTAGR---VA
Mvan_4762|M.vanbaalenii_PYR-1 DRVKVEVGDTVVMADSGLLERVLANVIDNALRYAPDGPVRVTAGR---VA
MAV_1170|M.avium_104 DRVKVDVGDAMVMADAGLLERVLANLIDNALRYAPNCVVRVNAGQ---VG
MAB_3251c|M.abscessus_ATCC_199 KRVHLDLGGAVVRADPGLLERVLANLVDNALRYS-QGEVRVSHEE---VD
Mflv_4711|M.gilvum_PYR-GCK MDVEMPPDDVIAEVDPRRVERILRNLIANAIDHAEHKPVQIRMAA---DV
MLBr_00774|M.leprae_Br4923 LLVDMPVDEVIAEVDARRVERILRNLIANAIDHSEHKPVRIRMAA---DE
TH_4550|M.thermoresistible__bu VEVDTTLSEAVTRGDATLLERLAHNLIENAVKYSGDDSPRVVVTTGSLSD
MUL_0464|M.ulcerans_Agy99 VEVLEGPGTPEVLGDEPRLRQVLSNLVGNALQHTPDSADVTVRVG--TAG
* . . * :.:: *:: *.: :: .
Mb1056c|M.bovis_AF2122/97 ERVLINVIDEGPGVPRGTEEQLFAPFQR--PGDHDNTTGVGLGMSVARGF
Rv1028c|M.tuberculosis_H37Rv ERVLINVIDEGPGVPRGTEEQLFAPFQR--PGDHDNTTGVGLGMSVARGF
MMAR_0634|M.marinum_M DRVLINVADEGPGIPRGAEEQMFAPFQR--LGDRDNRIGVGLGLSVAKGF
MSMEG_5395|M.smegmatis_MC2_155 NKVLIAVVDEGPGIPRGAEDALFAPFQR--LGDTNTTTGVGLGLSVAKGF
Mvan_4762|M.vanbaalenii_PYR-1 DRVLIAVADEGPGVARGAETELFAPFQR--LGDQDTSSGVGLGLSVARGF
MAV_1170|M.avium_104 DRVLINVIDEGPGIPHGAEEQIFEAFQR--LGDHDNTTGVGLGMSVARGF
MAB_3251c|M.abscessus_ATCC_199 DRTLVIVADHGKGLEASKRGAAFDAFQR--LGDRDNTVGVGLGLSVVKGF
Mflv_4711|M.gilvum_PYR-GCK DTVAVTVRDFGVGLRPGEEKLVFSRFWRADPSRVRRSGGTGLGLAISIED
MLBr_00774|M.leprae_Br4923 DTVAVTVRDYGIGLRPGEEKLVFSRFWRSDPSRVRRSGGTGLGLAISIED
TH_4550|M.thermoresistible__bu SQVFLRVSNNGEPIRDEDLPTLFEPFRR--LTRDTRASGAGLGLSIAAAI
MUL_0464|M.ulcerans_Agy99 ENAVLEVADKGPGMPAEDAARVFERFYRTDSSRARASGGTGLGLSIVHSL
. . : * : * : * * * *.***:::
Mb1056c|M.bovis_AF2122/97 VEAMGGTISATDTPGGGLTVVIDLAAPEDRP-------------------
Rv1028c|M.tuberculosis_H37Rv VEAMGGTISATDTPGGGLTVVIDLAAPEDRP-------------------
MMAR_0634|M.marinum_M VEAMGGTISATDTPGGGLTVVVDLAAA-----------------------
MSMEG_5395|M.smegmatis_MC2_155 VEAMGGTISAGDTPGGGLTVEIELAVPA----------------------
Mvan_4762|M.vanbaalenii_PYR-1 VEAMGGTISATDTPGGGMTVEIDLAAPR----------------------
MAV_1170|M.avium_104 VEAMGGTITATDTPGGGLTVMVDMAAPQSEGAA-----------------
MAB_3251c|M.abscessus_ATCC_199 VEAMEGTVNATDTAGGGLTMIVDLPSAGSAPTGAIR--------------
Mflv_4711|M.gilvum_PYR-GCK ARLHQGRLEAWGEPGKGACFRLTLPLVRGHKVTSSPLPVKPIET----AA
MLBr_00774|M.leprae_Br4923 ARLHQGRLEAWGEPGQGACFRLTLPLVRGHKVTTSPLPMKPILQPSPQAS
TH_4550|M.thermoresistible__bu VQAHQGTIEATARPDGGLTVEVVLPAPAAARP------------------
MUL_0464|M.ulcerans_Agy99 VKAHGGDVTLTTAPGEGCCFRVTLPRVSEAAVELTEPVS-----------
.. * : .. * . : :.
Mb1056c|M.bovis_AF2122/97 ---------------------
Rv1028c|M.tuberculosis_H37Rv ---------------------
MMAR_0634|M.marinum_M ---------------------
MSMEG_5395|M.smegmatis_MC2_155 ---------------------
Mvan_4762|M.vanbaalenii_PYR-1 ---------------------
MAV_1170|M.avium_104 ---------------------
MAB_3251c|M.abscessus_ATCC_199 ---------------------
Mflv_4711|M.gilvum_PYR-GCK GAG-------RRVREPAGESV
MLBr_00774|M.leprae_Br4923 TAGQQHGTQRQRLREHAERSR
TH_4550|M.thermoresistible__bu ---------------------
MUL_0464|M.ulcerans_Agy99 ---------------------