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VTTRASNASKRGELRIYLGAAPGVGKTYAMLGEAHRRLDRGTDLVAAVVETHGRKNTAELLAGIEVIPPR YIEYRGGRFPELDVPAVLDRKPQVVLVDELAHTNTPGSKNAKRWQDVDELLNAGITVISTVNVQHLDSLN DVVAAITGIEQQETVPDEVVRSADQIELVDITPEALRRRLSHGNVYAPERIDAALSNYFRRGNLTALREL ALLWLADQVDAALAKYRADNKITALWETRERVVVAVTGGTESETLVRRAFRIASKSSAELMVVHVVHGDG LTGISAAQMGKVRELAVSLGATVHTVVGDDVPTALLDFARDINATQLVLGTSRRSRWARMFDEGIGATVV QQSQKIDVHMVTHEAAKRGFRWSSTSPRQRHAASWAAALMVPSLICAFSVAILDPFLDVGGKSALFFVGV LVVALLGGVAPAALSAVLSGLLLNYFLTSPRHTFTMSDPDSALTIVVLLAVAVAVAALVDGAAKRAREAR HASREAELLALFAGSVLRGADLTALLERVRETYAQRAVSLLRETSDGATIVDCVGQDPCDRVAAADTAVE AGDEFWLLLSGRELPARDRRVLGAVANQAAGLVRQRELTEEAAKANAIAKADELSRSLLSAVSHDLRTPL AAAKAAASSLRSCDIDFSAEDTAELLATIEESVDALTALVGNLLDSSRLAAGVIHPELRPVYLEETVQRA LLGIRRGPTGYGRSAVDRVKVEVGDSVALADGGLLERVLANLIDNALRYAPDGLIRVTAGRVANKVLIAV VDEGPGIPRGAEDALFAPFQRLGDTNTTTGVGLGLSVAKGFVEAMGGTISAGDTPGGGLTVEIELAVPA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5395 | - | - | 100% (839) | sensor protein KdpD |
| M. smegmatis MC2 155 | MSMEG_5372 | - | 0.0 | 60.74% (838) | sensor protein KdpD |
| M. smegmatis MC2 155 | MSMEG_5487 | - | 7e-18 | 30.34% (234) | sensor histidine kinase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1056c | kdpD | 0.0 | 77.31% (833) | sensor protein KDPD |
| M. gilvum PYR-GCK | Mflv_4423 | - | 3e-21 | 30.92% (249) | multi-sensor signal transduction histidine kinase |
| M. tuberculosis H37Rv | Rv1028c | kdpD | 0.0 | 77.31% (833) | sensor protein KDPD |
| M. leprae Br4923 | MLBr_00774 | mtrB | 6e-17 | 29.65% (226) | putative two-component system sensor kinase |
| M. abscessus ATCC 19977 | MAB_3251c | - | 0.0 | 63.53% (828) | sensor protein KdpD |
| M. marinum M | MMAR_0634 | kdpD | 0.0 | 80.14% (831) | two-component system response phosphate sensor kinase, KdpD |
| M. avium 104 | MAV_1170 | - | 0.0 | 76.06% (848) | sensor protein KdpD |
| M. thermoresistible (build 8) | TH_2428 | - | 5e-20 | 32.61% (230) | PUTATIVE integral membrane sensor signal transduction histidine |
| M. ulcerans Agy99 | MUL_0464 | phoR | 4e-21 | 31.54% (279) | two component system response phosphate sensor kinase, PhoR |
| M. vanbaalenii PYR-1 | Mvan_4762 | - | 0.0 | 78.52% (838) | osmosensitive K+ channel signal transduction histidine kinase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1056c|M.bovis_AF2122/97 --------------------------------------------------
Rv1028c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0634|M.marinum_M --------------------------------------------------
MAV_1170|M.avium_104 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4762|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3251c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00774|M.leprae_Br4923 --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
TH_2428|M.thermoresistible__bu --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK MNWAQTPLGPTSEWPQSLQTAANILLSSRFPMWMAWGPDLTFFCNDAYRN
Mb1056c|M.bovis_AF2122/97 --------------------------------------------------
Rv1028c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0634|M.marinum_M --------------------------------------------------
MAV_1170|M.avium_104 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4762|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3251c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00774|M.leprae_Br4923 --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
TH_2428|M.thermoresistible__bu --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK VTLGRKYPWALGRPASEVWAEIWDDIGPRIERVLSTGVATWDTSLLLFLE
Mb1056c|M.bovis_AF2122/97 --------------------------------------------------
Rv1028c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0634|M.marinum_M --------------------------------------------------
MAV_1170|M.avium_104 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4762|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3251c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00774|M.leprae_Br4923 --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
TH_2428|M.thermoresistible__bu --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK RSGYTEESYHTFSYSPLRDDDGAVVGMLCVVSEDTLQVIGERRMATLRDL
Mb1056c|M.bovis_AF2122/97 --------------------------------------------------
Rv1028c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0634|M.marinum_M --------------------------------------------------
MAV_1170|M.avium_104 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4762|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3251c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00774|M.leprae_Br4923 --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
TH_2428|M.thermoresistible__bu --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK GSDPSVVRTEGEILSFVDRQLAQNLRDLPFTLTYLFDDDGSAHLAGMSGI
Mb1056c|M.bovis_AF2122/97 --------------------------------------------------
Rv1028c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0634|M.marinum_M --------------------------------------------------
MAV_1170|M.avium_104 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4762|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3251c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00774|M.leprae_Br4923 --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
TH_2428|M.thermoresistible__bu --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK TGDHPAAPDVLTGADGELWPVGPPAGGETVLLEVDTAPYPAMPTGDWREP
Mb1056c|M.bovis_AF2122/97 --------------------------------------------------
Rv1028c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0634|M.marinum_M --------------------------------------------------
MAV_1170|M.avium_104 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4762|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3251c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00774|M.leprae_Br4923 --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
TH_2428|M.thermoresistible__bu --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK PRQVLIVPLLQQGAAPTGFLVAGLNRYRVLDDAYRGFVALVAGHIAAGIG
Mb1056c|M.bovis_AF2122/97 --------------------------------------------------
Rv1028c|M.tuberculosis_H37Rv --------------------------------------------------
MMAR_0634|M.marinum_M --------------------------------------------------
MAV_1170|M.avium_104 --------------------------------------------------
MSMEG_5395|M.smegmatis_MC2_155 --------------------------------------------------
Mvan_4762|M.vanbaalenii_PYR-1 --------------------------------------------------
MAB_3251c|M.abscessus_ATCC_199 --------------------------------------------------
MLBr_00774|M.leprae_Br4923 --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
TH_2428|M.thermoresistible__bu --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK LSRSYRTQQMRAEELAELDRAKTTFFSNISHEFRTPLTLILDPVSELRRA
Mb1056c|M.bovis_AF2122/97 ----------MTLLFADLCAIFTPYRWMIEHVTTKRGQLRIYLGAAPGVG
Rv1028c|M.tuberculosis_H37Rv ----------MTLLFADLCAIFTPYRWMIEHVTTKRGQLRIYLGAAPGVG
MMAR_0634|M.marinum_M ---------------------------MTPDYPRKRGELRIYLGAAPGVG
MAV_1170|M.avium_104 -------------------------MTDVRDHHPKRGELRIYLGAAPGVG
MSMEG_5395|M.smegmatis_MC2_155 ---------------------MTTRASNAS----KRGELRIYLGAAPGVG
Mvan_4762|M.vanbaalenii_PYR-1 ---------------------MDDESVAASPHKAKRGELRIYLGAAPGVG
MAB_3251c|M.abscessus_ATCC_199 ----------------------------MPDGLRARGTLRIYLGAAPGVG
MLBr_00774|M.leprae_Br4923 --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
TH_2428|M.thermoresistible__bu --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK DTLGDAARQELDVVWRNGLRLNKLVNTLLDFSRIEAGRTQAHYQPVDLGA
Mb1056c|M.bovis_AF2122/97 KTYAMLGEAHRRLERGTDVVAAVVETHGRNKTAKLLEGIEMIPPRYVEYR
Rv1028c|M.tuberculosis_H37Rv KTYAMLGEAHRRLERGTDVVAAVVETHGRNKTAKLLEGIEMIPPRYVEYR
MMAR_0634|M.marinum_M KTFAMLGEAQRRLERGTDVVAAVVETHGRKRTAELLEGIERIPPKFIEYR
MAV_1170|M.avium_104 KTYSMLGEAHRRLERGTDLVAGVVETHGRAKTAELLEGIEIIPPRYIEYR
MSMEG_5395|M.smegmatis_MC2_155 KTYAMLGEAHRRLDRGTDLVAAVVETHGRKNTAELLAGIEVIPPRYIEYR
Mvan_4762|M.vanbaalenii_PYR-1 KTYAMLGEAHRRLERGTDVVAAVVETHGRKKTAELFEGIEIVPPKLIAYR
MAB_3251c|M.abscessus_ATCC_199 KTFAMLNEAHRRAGRGTDVVAAVVETHGRSKTAELLDGLELIPPKEMVHR
MLBr_00774|M.leprae_Br4923 ----MIFSSRRRIRG-----------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
TH_2428|M.thermoresistible__bu --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK VTAELASVFRSAIERAGLVFDVDCPPLGEEAYVDLDMWEKVIFNLLSNAL
Mb1056c|M.bovis_AF2122/97 GARFPELDVEAVLRRHPQVVLVDELAHTNTPGSKNPKRWQDVQEILDAGI
Rv1028c|M.tuberculosis_H37Rv GARFPELDVEAVLRRHPQVVLVDELAHTNTPGSKNPKRWQDVQEILDAGI
MMAR_0634|M.marinum_M GSRFAELDVEAVLRRQPQVVLVDELAHTNTPGSKNPKRWQDVEELLDAGI
MAV_1170|M.avium_104 GGRFPELDVPAVLARHPQVVLVDELAHTNTPGSKNPKRWQDVEELLDAGI
MSMEG_5395|M.smegmatis_MC2_155 GGRFPELDVPAVLDRKPQVVLVDELAHTNTPGSKNAKRWQDVDELLNAGI
Mvan_4762|M.vanbaalenii_PYR-1 GSDFAELDVEAVLRRNPQVVLVDELAHTNTPGSKNTKRWQDIEELLDAGI
MAB_3251c|M.abscessus_ATCC_199 GTAMYELDVDAVLERRPALVLIDEMAHTNVPGSRNPKRWQDIDEILDAGI
MLBr_00774|M.leprae_Br4923 -------------------------------------RWGRSGPMMRG--
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
TH_2428|M.thermoresistible__bu --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK KFTFEGSVSVTARRDGRGAVITVSDTGTGVPADEMPRLFERFHRIENTRA
Mb1056c|M.bovis_AF2122/97 TVISTVNIQHLEGLNDVVEQITGIEQKEK------------------IPD
Rv1028c|M.tuberculosis_H37Rv TVISTVNIQHLEGLNDVVEQITGIEQKEK------------------IPD
MMAR_0634|M.marinum_M TVISTVNVQHLESLNDVVAQITGIEQQEK------------------VPD
MAV_1170|M.avium_104 TVISTVNVQHLESLNDVVAQITGIEQKET------------------VPD
MSMEG_5395|M.smegmatis_MC2_155 TVISTVNVQHLDSLNDVVAAITGIEQQET------------------VPD
Mvan_4762|M.vanbaalenii_PYR-1 TVITTVNVQHLESLNDVVTQITGIEQQEK------------------VPD
MAB_3251c|M.abscessus_ATCC_199 DVLTTINVQHLESLNDVVEQITGIVQRET------------------VPD
MLBr_00774|M.leprae_Br4923 -----------------------MGALTR------------------VVG
MUL_0464|M.ulcerans_Agy99 -------------------------MAER------------------LPR
TH_2428|M.thermoresistible__bu -----------------------MTFAQP------------------YPP
Mflv_4423|M.gilvum_PYR-GCK RSNEGSGIGLALVKELVGLHGGTIEADSAESRGTTFTIRLPWGAGHLPAD
Mb1056c|M.bovis_AF2122/97 EIVRAADQVELVDITPEALRRRLAHGNVYAAERVDAALSNYFRTGNLTAL
Rv1028c|M.tuberculosis_H37Rv EIVRAADQVELVDITPEALRRRLAHGNVYAAERVDAALSNYFRTGNLTAL
MMAR_0634|M.marinum_M EIVRAAEQVELVDITPEALRRRLAHGNVYAAERVDAALANYFRTGNLTAL
MAV_1170|M.avium_104 SVVRQASQVELIDITPEALRRRLSHGNVYAPDRIDAALSNYFRRGNLTAL
MSMEG_5395|M.smegmatis_MC2_155 EVVRSADQIELVDITPEALRRRLSHGNVYAPERIDAALSNYFRRGNLTAL
Mvan_4762|M.vanbaalenii_PYR-1 EVVRAADQVELVDITPEALRRRLAHGNVYAPERVDAALSNYFRRGNLTAL
MAB_3251c|M.abscessus_ATCC_199 AVVRRAEQVELVDITPEALRRRMVHGNVYAPEKVGSALSNYFRTGNLTAL
MLBr_00774|M.leprae_Br4923 VVWRRSLQLRVVALT--------------------------------FGL
MUL_0464|M.ulcerans_Agy99 AVQLRVGLVAAT-----------------------------------LAL
TH_2428|M.thermoresistible__bu SPPQRQATSQPAS-------------------------------------
Mflv_4423|M.gilvum_PYR-GCK AVASQPRERRPGNTVDAYVEEALRWTPDGVREYVAESAQPTTGPEKPIGT
Mb1056c|M.bovis_AF2122/97 REIALLWLADQVDAALEKYRADKKITATWEARERVVVAVTGGPESETLVR
Rv1028c|M.tuberculosis_H37Rv REIALLWLADQVDAALEKYRADKKITATWEARERVVVAVTGGPESETLVR
MMAR_0634|M.marinum_M RELALLWLADQVDAALEKYRADKKITATWEARERVVVAVTGGPESETLVR
MAV_1170|M.avium_104 RELALLWLADQVDTALAKYRAENKITDTWEARERVVVAVTGGPESETLVR
MSMEG_5395|M.smegmatis_MC2_155 RELALLWLADQVDAALAKYRADNKITALWETRERVVVAVTGGTESETLVR
Mvan_4762|M.vanbaalenii_PYR-1 RELALLWLADQVDSALEKYRADNKITDTWEARERVVVAVTGGPESETLVR
MAB_3251c|M.abscessus_ATCC_199 RELALLWLADQVDAALAKYRSDNRITKTWEARERVVVAVTGGPESETLVR
MLBr_00774|M.leprae_Br4923 SLAVILALGFVLTSQLTSRVLDVKVRVAIEQIERARTTVTGIVNGEETRS
MUL_0464|M.ulcerans_Agy99 VLCGLLASGVAVTSILRHSLVS-RIDSTLLEASRTWAQASWRHSMPSVEG
TH_2428|M.thermoresistible__bu -SLSLRWRVMLLAMSMVAMVVVLMSIALYAVVSRALYNDIDN----QLHS
Mflv_4423|M.gilvum_PYR-GCK GTLARVLVADDNADMREYLGRLLRSDGYAVEAVVDGWQALEAIRAEPPDL
Mb1056c|M.bovis_AF2122/97 RASRIASKSSAELMVVHVIRGDDLAGVSAPQLGRVRELATSLGATMHTVV
Rv1028c|M.tuberculosis_H37Rv RASRIASKSSAELMVVHVIRGDGLAGVSAPQLGRVRELATSLGATMHTVV
MMAR_0634|M.marinum_M RAFRIASKASAELMVVHLARGDGLSGVAAPQMGKVRELAASLGATVHTVV
MAV_1170|M.avium_104 RASRIASKSSAELMVVHVIRGDGLAGLSESRMAKIRELASSLDASLHTIV
MSMEG_5395|M.smegmatis_MC2_155 RAFRIASKSSAELMVVHVVHGDGLTGISAAQMGKVRELAVSLGATVHTVV
Mvan_4762|M.vanbaalenii_PYR-1 RASRIASKSSAELMVVHVVQGDGLSGVSGPQMGKVRELAASIGATLHTVV
MAB_3251c|M.abscessus_ATCC_199 RASRIAAKSSAELLVVHVVRGDGLVGASTAVMTRVRRLANDIGASVQAVT
MLBr_00774|M.leprae_Br4923 LDSSLQLARNTLTSKTDPTSGAGLVGAFDAVL-----IVPGDGPRTATTA
MUL_0464|M.ulcerans_Agy99 PDP--ARPPSKFYVRSISPDGRAMTAIN--------DRNAEPALPADNDV
TH_2428|M.thermoresistible__bu RARLLIESGSLAADPGRAIEGTAYSDVNAMLVNPGRSIYTANQQGEALPL
Mflv_4423|M.gilvum_PYR-GCK VISDVMMPRLDGLGLVAELRADRRTAAVPVLLLSARAGQEASISGLQAGA
.
Mb1056c|M.bovis_AF2122/97 GD---DVPTALLDFAREMNATQLVVGTSRRSRWARLFDEGIGARTVQESG
Rv1028c|M.tuberculosis_H37Rv GD---DVPTALLDFAREMNATQLVVGTSRRSRWARLFDEGIGARTVQEPG
MMAR_0634|M.marinum_M GD---DVPTALLDFAREMNATQLVLGTSRRSRWARVLDEGIGATVVQQSG
MAV_1170|M.avium_104 GD---EVPAALLEFAREMNATQLVIGTSRRSRWARLFEEGIGPRIVELSG
MSMEG_5395|M.smegmatis_MC2_155 GD---DVPTALLDFARDINATQLVLGTSRRSRWARMFDEGIGATVVQQSQ
Mvan_4762|M.vanbaalenii_PYR-1 GDGAGGVPAALLDFAREMNATQLVLGTSRRSRWARIFDEGIGATVVQKSG
MAB_3251c|M.abscessus_ATCC_199 GD---DVPQTLLDFARGVNATQLVLGTSRRSRWARILDEGVAAAVIRDSG
MLBr_00774|M.leprae_Br4923 GP-VDQVPNSLRGFIKAG---------QAAYQYATVHTEGFSGPALIIG-
MUL_0464|M.ulcerans_Agy99 GS----DPTTLPSVNGS------------NIEWRAVSVHGP---------
TH_2428|M.thermoresistible__bu GEPERQVLSGELVMS------------LRTADQQRVLAIHLS--------
Mflv_4423|M.gilvum_PYR-GCK DDYLVKPFAAAELLARVRANIQLARLREGHARWRTALVDSLQEAFFVCDE
. .
Mb1056c|M.bovis_AF2122/97 GIDVHMVTHPAASRASGWSRVSP-----------RERHIASWLAALVVPS
Rv1028c|M.tuberculosis_H37Rv GIDVHMVTHPAASRASGWSRVSP-----------RERHIASWLAALVVPS
MMAR_0634|M.marinum_M PIDVHMVTHQEAGRPARWSWLWP-----------REHHLVSWLAAVVVPS
MAV_1170|M.avium_104 KIDVHLVTHEESKRGFRASSLAP-----------RERRVASWLAALIVPS
MSMEG_5395|M.smegmatis_MC2_155 KIDVHMVTHEAAKRGFRWSSTSP-----------RQRHAASWAAALMVPS
Mvan_4762|M.vanbaalenii_PYR-1 RIDVHMVTHEQAGGESLWARVSP-----------RQRHAVSWLAALAVPG
MAB_3251c|M.abscessus_ATCC_199 AIDVHMVTHGHTSGRLRSWSVPQD---------GRKRLIINWLAAILVP-
MLBr_00774|M.leprae_Br4923 --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
TH_2428|M.thermoresistible__bu --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK HGAVVEINPAFTEILGYDSTGLPYPLMHPWWPLKGSDAEANRRVEEAFGS
Mb1056c|M.bovis_AF2122/97 VICAITVAWLDRFMGIGGESALFFIGVLIVALLGGVAPAALSALLSGMLL
Rv1028c|M.tuberculosis_H37Rv VICAITVAWLDRFMGIGGESALFFIGVLIVALLGGVAPAALSALLSGMLL
MMAR_0634|M.marinum_M LICALTVAWLDRFLAVGGESALFVIGVLVVALLGGVAPAALSAVLSGLLL
MAV_1170|M.avium_104 VICAVTVTWLDPYLDTGGESALFFVGVLLVGLLGGIAPAALSAVLSGLLL
MSMEG_5395|M.smegmatis_MC2_155 LICAFSVAILDPFLDVGGKSALFFVGVLVVALLGGVAPAALSAVLSGLLL
Mvan_4762|M.vanbaalenii_PYR-1 AICAATVLLLDRFLGIGGESAMFFIGVLVVALLGGVAPAALSAVLSGVLL
MAB_3251c|M.abscessus_ATCC_199 PATALFIHFFDTAFGVGSKSALFLIAVLGVSLLGGVSTALVSAVISGLLL
MLBr_00774|M.leprae_Br4923 ------------------------------------TPTSSQVTNLELYL
MUL_0464|M.ulcerans_Agy99 -------------------------------------QGGLTTVAIDLSD
TH_2428|M.thermoresistible__bu -------------------------------------NGSSLLISKSLAP
Mflv_4423|M.gilvum_PYR-GCK FMRDPHGTLTEVPVTHRDGHRLYVTVTFSHADDPETGRDVIVGTLRDVTA
:
Mb1056c|M.bovis_AF2122/97 NYFLTEPRYTWTIAEPDAAVTEFVLLAMAVAVAVLVDGAASRTREARRAS
Rv1028c|M.tuberculosis_H37Rv NYFLTEPRYTWTIAEPDAAVTEFVLLAMAVAVAVLVDGAASRTREARRAS
MMAR_0634|M.marinum_M NYFLIEPRYTFTIADPDNAVTTLVLLVVAVAVAALVDNAAKRSREAGRAS
MAV_1170|M.avium_104 NYYLIAPRHSFTIAEPNSAITELVLLLIAVAVAVLVDFAAKRTREARRAS
MSMEG_5395|M.smegmatis_MC2_155 NYFLTSPRHTFTMSDPDSALTIVVLLAVAVAVAALVDGAAKRAREARHAS
Mvan_4762|M.vanbaalenii_PYR-1 NFFLVEPRHTFTISEPDSAITIVVLLVVAVAVAALVDGAANRTRESRRAA
MAB_3251c|M.abscessus_ATCC_199 NFLFVAPRYSFTIGETDNALTILMMMVTAVAVAALVDAAATRARQARRAS
MLBr_00774|M.leprae_Br4923 IFPLKNEQATVTLVRGTMATGGMVLLVLLSGIALLVSRQVVVP--VRSAS
MUL_0464|M.ulcerans_Agy99 VQHTVRSLVWLQIGIGAGVLVVVGLAGFAVVQRSLRPLSEVEQTAAAIAS
TH_2428|M.thermoresistible__bu TMEVLRRLGTVLLIVGGIGVAVAAIAGGMVARAGLRP--------VSRLT
Mflv_4423|M.gilvum_PYR-GCK ERYIVQRESALASLNEKLAQADTLDDAVLAAAEEFSSIWSARRVVAATWP
: .
Mb1056c|M.bovis_AF2122/97 QEAELLALFAGSVLRGADLATLLQRVRETYSQRAVTMLR----VRQGAST
Rv1028c|M.tuberculosis_H37Rv QEAELLALFAGSVLRGADLATLLQRVRETYSQRAVTMLR----VRQGAST
MMAR_0634|M.marinum_M REAELLALFAGSVLRGADLEALLEKVRETYSQRAVSILR----IEAGTSQ
MAV_1170|M.avium_104 QEAELLTLFAGSVLRGADLETLLERVRETYAQRSVSMLRESEDARAGGTK
MSMEG_5395|M.smegmatis_MC2_155 REAELLALFAGSVLRGADLTALLERVRETYAQRAVSLLR------ETSDG
Mvan_4762|M.vanbaalenii_PYR-1 REAELLALFAGAVLRGADLNTLLERVREAYSQQSVTLVR------GEAHG
MAB_3251c|M.abscessus_ATCC_199 REAELLALFAGGVLVNSDLSALLERVRTTYNQTAVSLLC---------AE
MLBr_00774|M.leprae_Br4923 RIAERFAEGHLSERMPVRGEDDMARLAVSFNDMAESLSR-----------
MUL_0464|M.ulcerans_Agy99 GQLDRRVPERDPRTEVGQLSLAMNGMLSQIQVALAASED-----------
TH_2428|M.thermoresistible__bu EAAERVARTDDLRPIPVVGSDELARLTEAFNMMLRALAE-----------
Mflv_4423|M.gilvum_PYR-GCK DEPDGEHESDAPSLTVVGAPATWDGLPGSARELILTLRRDHLLAPHTSDA
: : :
Mb1056c|M.bovis_AF2122/97 GETVACVGTNPCRDVDSADTAIEVG----DDEFWMLMAGRKLAARDRRVL
Rv1028c|M.tuberculosis_H37Rv GETVACVGTNPCRDVDSADTAIEVG----DDEFWMLMAGRKLAARDRRVL
MMAR_0634|M.marinum_M GAIVSCVGEDPCVDVDTADTAIDVG----DDEFWMLMAGRKLLARDRRVL
MAV_1170|M.avium_104 TQVVACVGRDPCVSVDAADTAIEVGGPD-SSEFQMLLAGRKLSARDRRVL
MSMEG_5395|M.smegmatis_MC2_155 ATIVDCVGQDPCDRVAAADTAVEAG-----DEFWLLLSGRELPARDRRVL
Mvan_4762|M.vanbaalenii_PYR-1 GGVVGCAGSEPCVTVETADTAIEVGSKDDPEEFWLLLAGRRLDARDRRVL
MAB_3251c|M.abscessus_ATCC_199 GPAVASVGEDPPTRESEADSVFRVD----DGAYALALNGPPVPSSDARVL
MLBr_00774|M.leprae_Br4923 --------------------------------------------------
MUL_0464|M.ulcerans_Agy99 --------------------------------------------------
TH_2428|M.thermoresistible__bu --------------------------------------------------
Mflv_4423|M.gilvum_PYR-GCK GAAGVALRHPRGVLVLYVELPEQRLFTAEDDTLLTVLAGRLGQGLQRVHQ
Mb1056c|M.bovis_AF2122/97 TAVATQAAGLVKQRELAEEAGQAEAIARADELRRSLLSAVSHDLR-----
Rv1028c|M.tuberculosis_H37Rv TAVATQAAGLVKQRELAEEAGQAEAIARADELRRSLLSAVSHDLR-----
MMAR_0634|M.marinum_M TAVAKQAAGLIKQRELADEAGKAQAIEQADQLRRALLSAVSHDLR-----
MAV_1170|M.avium_104 SAVARQAAGLIRQRELAEEASRTEAIVRADELRRSLLSAVSHDLR-----
MSMEG_5395|M.smegmatis_MC2_155 GAVANQAAGLVRQRELTEEAAKANAIAKADELSRSLLSAVSHDLR-----
Mvan_4762|M.vanbaalenii_PYR-1 GAVANQAAGLARQRELAEEAGRAEAIARADELRRSLLSAVSHDLR-----
MAB_3251c|M.abscessus_ATCC_199 QVVAGTAVGLVRSARLAEEASQASALAEADRLRRALLSAVSHDLR-----
MLBr_00774|M.leprae_Br4923 ---------------------QITQLEEFGNLQRRFTSDVSHELR-----
MUL_0464|M.ulcerans_Agy99 ---------------------SAEKARSSEERMRRFITDASHELR-----
TH_2428|M.thermoresistible__bu ----------------------------SRERQARLVADAGHELR-----
Mflv_4423|M.gilvum_PYR-GCK IDQQRETALALQHAILGPSLSSAFAVRYQPATRPLQVGGDWYDVVDLEDG
:::
Mb1056c|M.bovis_AF2122/97 -----------------TPLAAAKVAVSSLRTEDV----AFSPEDTAELL
Rv1028c|M.tuberculosis_H37Rv -----------------TPLAAAKVAVSSLRTEDV----AFSPEDTAELL
MMAR_0634|M.marinum_M -----------------TPLAAAKAAVSSLRSDDV----DFSADDMGELL
MAV_1170|M.avium_104 -----------------TPLAAAKVAVSSLRAEDV----AFSPTDTAELL
MSMEG_5395|M.smegmatis_MC2_155 -----------------TPLAAAKAAASSLRSCDI----DFSAEDTAELL
Mvan_4762|M.vanbaalenii_PYR-1 -----------------TPLAAAKAAVSSLRSEDV----GFSPEDTAELL
MAB_3251c|M.abscessus_ATCC_199 -----------------TPLAAVKAAVSSLRSPDI----EFSPEDTAELL
MLBr_00774|M.leprae_Br4923 -----------------TPLTTVRMAADLIYDHSS----DLDP-TLRRST
MUL_0464|M.ulcerans_Agy99 -----------------TPLTTIRGFAELYRQG--------AARDVAMLL
TH_2428|M.thermoresistible__bu -----------------TPLTSLRTNVELLMASQQPGAPGLPEEEMAGLR
Mflv_4423|M.gilvum_PYR-GCK RIGLIVGDCVGHGLAAATVMGQLRSACRALLLEHPSPAAALSALDRFAAR
* : :
Mb1056c|M.bovis_AF2122/97 ATIEESIDQLTALVAN-LLDSSRLAAGVIRPQLRRAYLEEAVQRALVSIG
Rv1028c|M.tuberculosis_H37Rv ATIEESIDQLTALVAN-LLDSSRLAAGVIRPQLRRAYLEEAVQRALVSIG
MMAR_0634|M.marinum_M ATIEESVDQLTALVGN-LLDSSRLAAGVVRPQLRRVYLEETVQRALLGIS
MAV_1170|M.avium_104 ATIEESIDQLTALVGN-LLDSSRLAAGAIHPDLRRVYLEEAVQRALVSIG
MSMEG_5395|M.smegmatis_MC2_155 ATIEESVDALTALVGN-LLDSSRLAAGVIHPELRPVYLEETVQRALLGIR
Mvan_4762|M.vanbaalenii_PYR-1 ATVEESIDQLSGLVGN-LLDSSRLAAGVVRPELQPVYLEEAVPRALLGIS
MAB_3251c|M.abscessus_ATCC_199 ATVEESADQLTALVGN-LLDSSRLAAGVVKPRAVPVYVDEIAQRALLGAT
MLBr_00774|M.leprae_Br4923 ELMVSELDRFETLLND-LLEISRHDAGVAELSVEAVDLRVMVNNALGNVG
MUL_0464|M.ulcerans_Agy99 SRIESEASRMGLLVDD-LLTLARLDV---QRPLERNRVDLLVLAADAVHD
TH_2428|M.thermoresistible__bu ADVIAQIEELSTLVGD-LVDLTRDDAG--GVIHEPVDIADVVDRSLERVR
Mflv_4423|M.gilvum_PYR-GCK LPGARCTTAFCAVLDPRIGEVVYSCAGHPPPIMVTADRTTELLEGARATP
: :: : . .
Mb1056c|M.bovis_AF2122/97 KGATGFYRSGIDRVKVDVGDAVAMADAGLLERVLANLIDNALRYAPDCVV
Rv1028c|M.tuberculosis_H37Rv KGATGFYRSGIDRVKVDVGDAVAMADAGLLERVLANLIDNALRYAPDCVV
MMAR_0634|M.marinum_M RGATGYGRSGLDRVKVEVGGAVAIADAGLLERVLANLIDNGLRYAPDSPV
MAV_1170|M.avium_104 KGATGFFRSAIDRVKVDVGDAMVMADAGLLERVLANLIDNALRYAPNCVV
MSMEG_5395|M.smegmatis_MC2_155 RGPTGYGRSAVDRVKVEVGDSVALADGGLLERVLANLIDNALRYAPDGLI
Mvan_4762|M.vanbaalenii_PYR-1 RGSTGL-RAGLDRVKVEVGDTVVMADSGLLERVLANVIDNALRYAPDGPV
MAB_3251c|M.abscessus_ATCC_199 E-------NDRKRVHLDLGGAVVRADPGLLERVLANLVDNALRYS-QGEV
MLBr_00774|M.leprae_Br4923 HLAEEAG--IELLVDMPVDEVIAEVDARRVERILRNLIANAIDHSEHKPV
MUL_0464|M.ulcerans_Agy99 ARAIDRKRAITVEVLEGPGTPEVLGDEPRLRQVLSNLVGNALQHTPDSAD
TH_2428|M.thermoresistible__bu RRRND------IDFDIEVVPWQVYGDAAGLSRAVMNLLDNAAKWSPSGGR
Mflv_4423|M.gilvum_PYR-GCK LGLKNPPHRTEARVTMPARATLLLYTDGLVERRRE-SIDDGIARATDVVQ
. : : : :. :
Mb1056c|M.bovis_AF2122/97 R-VNAGRVR-ERVLINVIDEGPGVPRGTEEQLFAP---------------
Rv1028c|M.tuberculosis_H37Rv R-VNAGRVR-ERVLINVIDEGPGVPRGTEEQLFAP---------------
MMAR_0634|M.marinum_M R-VYAGRVG-DRVLINVADEGPGIPRGAEEQMFAP---------------
MAV_1170|M.avium_104 R-VNAGQVG-DRVLINVIDEGPGIPHGAEEQIFEA---------------
MSMEG_5395|M.smegmatis_MC2_155 R-VTAGRVA-NKVLIAVVDEGPGIPRGAEDALFAP---------------
Mvan_4762|M.vanbaalenii_PYR-1 R-VTAGRVA-DRVLIAVADEGPGVARGAETELFAP---------------
MAB_3251c|M.abscessus_ATCC_199 R-VSHEEVD-DRTLVIVADHGKGLEASKRGAAFDA---------------
MLBr_00774|M.leprae_Br4923 R-IRMAADE-DTVAVTVRDYGIGLRPGEEKLVFSR---------------
MUL_0464|M.ulcerans_Agy99 VTVRVGTAG-ENAVLEVADKGPGMPAEDAARVFER---------------
TH_2428|M.thermoresistible__bu VGVRLTQVDPVHAELVVSDHGPGIPPQERRLVFER---------------
Mflv_4423|M.gilvum_PYR-GCK GNRATDLDQLANVIMARLAPADGYHDDVALLLYRQPEPLDLDFPADVAEL
. : . * :
Mb1056c|M.bovis_AF2122/97 -----FQR--PGDHDNTTGVGLGMSVARGFVEAMGGTISATDTPGGG---
Rv1028c|M.tuberculosis_H37Rv -----FQR--PGDHDNTTGVGLGMSVARGFVEAMGGTISATDTPGGG---
MMAR_0634|M.marinum_M -----FQR--LGDRDNRIGVGLGLSVAKGFVEAMGGTISATDTPGGG---
MAV_1170|M.avium_104 -----FQR--LGDHDNTTGVGLGMSVARGFVEAMGGTITATDTPGGG---
MSMEG_5395|M.smegmatis_MC2_155 -----FQR--LGDTNTTTGVGLGLSVAKGFVEAMGGTISAGDTPGGG---
Mvan_4762|M.vanbaalenii_PYR-1 -----FQR--LGDQDTSSGVGLGLSVARGFVEAMGGTISATDTPGGG---
MAB_3251c|M.abscessus_ATCC_199 -----FQR--LGDRDNTVGVGLGLSVVKGFVEAMEGTVNATDTAGGG---
MLBr_00774|M.leprae_Br4923 -----FWRSDPSRVRRSGGTGLGLAISIEDARLHQGRLEAWGEPGQG---
MUL_0464|M.ulcerans_Agy99 -----FYRTDSSRARASGGTGLGLSIVHSLVKAHGGDVTLTTAPGEG---
TH_2428|M.thermoresistible__bu -----FYR--STTARSMPGSGLGLAIVKQVVLKHGGTLRVEDTVPGGQPP
Mflv_4423|M.gilvum_PYR-GCK AGSRTVLRGWLDSAGVPQDQALDVLIAVGEALANAIEHGHRDDPGGR---
. * . .*.: : .
Mb1056c|M.bovis_AF2122/97 -LTVVIDLAAPEDRP-----------------------------------
Rv1028c|M.tuberculosis_H37Rv -LTVVIDLAAPEDRP-----------------------------------
MMAR_0634|M.marinum_M -LTVVVDLAAA---------------------------------------
MAV_1170|M.avium_104 -LTVMVDMAAPQSEGAA---------------------------------
MSMEG_5395|M.smegmatis_MC2_155 -LTVEIELAVPA--------------------------------------
Mvan_4762|M.vanbaalenii_PYR-1 -MTVEIDLAAPR--------------------------------------
MAB_3251c|M.abscessus_ATCC_199 -LTMIVDLPSAGSAPTGAIR------------------------------
MLBr_00774|M.leprae_Br4923 -ACFRLTLPLVRGHKVTTSPLPMKPILQPSPQASTAGQQHGTQRQRLREH
MUL_0464|M.ulcerans_Agy99 -CCFRVTLPRVSEAAVELTEPVS---------------------------
TH_2428|M.thermoresistible__bu GTSIHVVLPGRPLSGVPPASQEPQPPQHAPGADPHAPTQTGNDAVQSVFT
Mflv_4423|M.gilvum_PYR-GCK VRLRAVALPDRVQLTIIDTGSWKAPDDVPALHRGRGIALMKALMQDVTID
: :.
Mb1056c|M.bovis_AF2122/97 ---------------
Rv1028c|M.tuberculosis_H37Rv ---------------
MMAR_0634|M.marinum_M ---------------
MAV_1170|M.avium_104 ---------------
MSMEG_5395|M.smegmatis_MC2_155 ---------------
Mvan_4762|M.vanbaalenii_PYR-1 ---------------
MAB_3251c|M.abscessus_ATCC_199 ---------------
MLBr_00774|M.leprae_Br4923 AERSR----------
MUL_0464|M.ulcerans_Agy99 ---------------
TH_2428|M.thermoresistible__bu AENK-----------
Mflv_4423|M.gilvum_PYR-GCK SQTTGTTVHMNTRIA